N'Golo Kante was omitted as Frank Lampard named his first starting line-up since returning to Chelsea as caretaker manager, with the midfielder rested ahead of the Blues' Champions League trip to Real Madrid.

Lampard opted to make two changes to Chelsea's side for Saturday's Premier League trip to Wolves, introducing England internationals Raheem Sterling and Conor Gallagher.

With Chelsea reverting to a back four after Bruno Saltor used a 3-5-2 system in Tuesday's goalless draw with Liverpool, Ben Chilwell was dropped to the bench and Kante was absent entirely.

Kante made his first Premier League start since last August against Liverpool, having missed the majority of the campaign with a hamstring injury.

However, Lampard played down any concerns regarding Kante's condition before kick-off, telling Sky Sports: "There's no worries with N'Golo. We're fine with him and managing him through. 

"He's been out for a long time so we have a way of managing him. I was aware of that when I was at the club before.

"Then there are a couple of other selection issues, some small concerns, so we have to protect a couple of the players in the squad."

Mason Mount was also absent for the Blues, with reports suggesting the midfielder suffered a recurrence of a previous injury in training on Friday.

The Athletic reported Mount – who has been linked with a move away after failing to agree a new contract with the Blues – could also miss the first leg of Chelsea's quarter-final tie with Madrid.

Chelsea travel to the Santiago Bernabeu to face Carlo Ancelotti's European champions on Wednesday, before welcoming Los Blancos to Stamford Bridge six days later.

Arsenal face another major obstacle in their quest to land a first Premier League title in 19 years when they travel to Liverpool on Sunday.

The Gunners have historically struggled at Anfield, though Mikel Arteta's men have passed most tests this season en route to opening up a healthy lead over Manchester City.

While Arsenal will be looking to continue their good form, having won seven league games in a row, it is the start of another new chapter for Chelsea when they head to Wolves.

Frank Lampard was this week appointed as caretaker manager for the rest of the season following the sacking of Graham Potter, with Chelsea way down in 11th place.

There are plenty of other big games at the top and bottom of the division this weekend, not least at Old Trafford where Manchester United and Everton face off.

United got their top-four hopes back on track in midweek and will be seeking some momentum when they take on an Everton side sitting level on points with the bottom three.

Here, with the help of Opta data, Stats Perform has provided some key insights and predictions.

Manchester United v Everton

United have dominated this fixture down the years, with their 38 Premier League wins against Everton the second most one team has over another after the Red Devils themselves against Tottenham (39 wins).

Erik ten Hag's men have won both meetings with Everton in all competitions this term – 2-1 in the league at Goodison Park and 3-1 in the FA Cup on home soil – and could make it three wins in a single campaign against them for the third time (after 1993-94 and 2015-16 seasons).

Everton have improved since Sean Dyche took charge, picking up 12 points from their nine league games under him, with that seven more than they managed in their final 12 games under Lampard.

Best bet – Everton to score at Old Trafford: The Toffees' away form this season may be terrible, as is their overall record at United, but they have scored in each of their past nine Premier League games at Old Trafford, with that the Red Devils' longest run without a clean sheet against a single opponent in the competition.

Long shot – Everton to avoid defeat: Scoring away at United is one thing; holding on for a point or more is another. Everton have won just one of their past 29 away league meetings with United, but their past three visits to Old Trafford have finished all square.

Opta prediction: United failed to win any of their six matches in the early Saturday kick-off slot last season, but they have won all three such games this campaign, including a 2-1 win over Manchester City in January. Everton have won just two of their past 31 away league games, meanwhile, and Opta's model gives them only a 20.6 per cent chance of winning at Old Trafford. United are given a 52.7 per cent chance of success, meanwhile, and the draw is rated at 26.7 per cent.

Wolves v Chelsea

Chelsea have failed to win on their past two league visits to Molineux, but the good news is that their most recent victory there came in September 2019 under Lampard.

Wolves are unbeaten in their three Premier League games against opponents from London under the watch of Julen Lopetegui, having failed to win any of their previous 11 such matches prior to the Spaniard's arrival.

The Blues have picked up just 16 points from 14 away top-flight matches, which is their lowest return after 14 road games in a single campaign since 2000-01 (nine).

Best bet – Wolves to win without conceding: Given Chelsea's form, a Wolves win this weekend would hardly be the biggest of surprises – especially considering Lopetegui's men have won their past three league games against sides starting the day above them without letting in a goal (1-0 v West Ham, 3-0 v Liverpool and 1-0 v Tottenham).

Long shot – Raheem Sterling to score or assist: The Chelsea winger has been directly involved in just one goal in his past six matches, but since the start of the 2019-20 campaign, only Manchester City playmaker Kevin De Bruyne (nine) has been directly involved in more league goals at Molineux than Sterling among visiting players (three goals, two assists).

Opta prediction: Wolves are winless in their past four Premier League games against Chelsea since beating them 2-1 at Molineux in December 2020. The Blues will be hoping the new (well, returning) manager bounce pays off and the Opta model makes them favourites to win with a 42.3 per cent backing, compared to 27.9 per cent for Wolves and 29.8 per cent for the draw.

Liverpool v Arsenal

Arsenal are facing Liverpool as Premier League leaders for the ninth time, with the previous eight occasions producing a total of 33 goals at an average of over four per game.

Since briefly surrendering top spot to Man City following a 3-1 defeat in February, Arsenal have won their last seven Premier League games. They have scored at least three goals in six of these, including the last five in a row.

Liverpool have won five of their last six Premier League home games (D1), including each of the last three by an aggregate score 11-0. The Reds have not conceded in any of their past seven hours and 26 minutes of league football at Anfield, since Kiernan Dewsbury-Hall's strike for Leicester City in December.

Best bet – Mohamed Salah to score or assist: The Egypt international is expected to be recalled by Jurgen Klopp and that could spell bad news for Arsenal. Salah has been involved in 105 league goals in 105 games at Anfield for Liverpool (74 goals, 31 assists) and has scored in three successive home league appearances for the Reds.

Long shot – Arsenal to lose without scoring: The Gunners have lost on their last six league visits to Anfield, conceding at least three goals each time. They have failed to score against the Reds on 20 occasions in the Premier League era, which is their worst record against any team in the division.

Opta prediction: Arsenal won the reverse fixture with Liverpool 3-2 in the first major sign they were the real deal this season, though not since the 2009-10 campaign have they pulled off the league double in this fixture. They have a 22.6 per cent chance of doing so this weekend, according to the Opta model, while Liverpool are rated at 51 per cent to pick up the three points. A draw is given a 26.4 per cent chance of happening.

Wolves winger Daniel Podence has been charged by the Football Association (FA) for allegedly spitting at Nottingham Forest's Brennan Johnson in Saturday's 1-1 Premier League draw.

During a disagreement between the two sets of players towards the end of the second half, Podence and Johnson exchanged words at close proximity.

Although replays appeared to show Podence in the act of spitting, footage was unable to conclusively prove if the Portugal international actually spat, and therefore the VAR review did not lead to a red card.

Johnson was asked about the incident at full-time and, while he told Sky Sports he was not going to "allegate [Podence]", the Forest player also claimed he "felt like some sort of spit came towards my face".

The FA seemingly saw enough to deem Podence worthy of retrospective punishment on Wednesday.

A statement read: "Wolverhampton Wanderers' Daniel Podence has been charged after the forward allegedly spat at an opposing player during the 90th minute."

The FA also charged Forest for their players surrounding the referee in the first half, while both teams' assistant managers will answer charges of improper and/or violent conduct.

Liverpool are reportedly no longer pursuing Wolves midfielder Matheus Nunes and will instead pivot to Brighton and Hove Albion young gun Moises Caicedo or Chelsea and England talent Mason Mount.

The decision to turn their attention away from Nunes comes after Wolves removed a release clause in his contract that would have made him available for £44million in the upcoming transfer window, according to The Mirror.

The report states Wolves will still entertain the possibility of selling Nunes, but will now demand at least £50m for the player they paid £38m for in an August transfer from Sporting CP.

TOP STORY – LIVERPOOL TURN TO CAICEDO, MOUNT AFTER NUNES REVELATION

With Nunes out of the equation, The Mirror is reporting Borussia Dortmund's Jude Bellingham remains the top priority, but Liverpool will investigate more "realistic" moves for Caicedo or Mount.

Caicedo, 21, signed a new contract with Brighton after the club turned down a £70m offer from Arsenal in January, but according to Football Insider the Seagulls were primarily against letting a top talent leave mid-season and will be far more open to discussions in the off-season.

Mount, 24, now has 15 months remaining on his Chelsea contract and has shown no signs of signing an extension, making him a prime candidate to leave the club in an effort to balance their books after lavish spending in the past 12 months.

ROUND-UP

– The Daily Mail is reporting Manchester United, Liverpool and Tottenham are among a host of clubs with interest in the £40million (€45.6m) release clause of 26-year-old Napoli centre-back Kim Min-jae, who would prefer a Premier League move if he is to leave Serie A.

– According to Fabrizio Romano, Saudi Arabian club Al-Hilal have made an official offer to impending free agent Lionel Messi that would pay him £350m per year.

– Lazio are trying to convince star 28-year-old midfielder Sergej Milinkovic-Savic to sign a new two-year extension to repel interest from Paris Saint-Germain, Arsenal, Juventus, United and Chelsea, per Football Italia.

– Sky Sports Germany's Florian Plettenberg is reporting RB Leipzig and Inter are both pushing to sign breakout 23-year-old Tigre striker Mateo Retegui after the Argentine-born talent made his international debut for Italy recently.

– According to Mundo Deportivo, Atletico Madrid have offered 30-year-old striker Alvaro Morata a contract extension as he prepares to enter the final year of his current deal, although the club are willing to sell him if he would prefer a new challenge.

Sunday saw two more Premier League bosses dismissed from their roles.

Graham Potter's sacking by Chelsea followed on from Leicester City cutting ties with Brendan Rodgers.

That pair of dismissals took the total count of managerial departures for the season to 13 in England's top tier. Twelve of those have been sackings.

According to Opta, it is the most managerial sackings in a Premier League season by three.

The previous high mark of 10 (set in the 2013-14 season and equalled in 2017-18) was matched last season.

Yet this campaign has been even more extreme. Here, Stats Perform assesses the 13 managers to have departed.

Scott Parker - Bournemouth (August 30)

Just four league games had passed when Bournemouth became the first club to blink, sacking Parker on the back of a humiliating 9-0 defeat to Liverpool. Parker went on to join Club Brugge in Belgium, but lasted less than three months, winning just two of 12 matches. His replacement at Bournemouth, Gary O'Neil, has the Cherries in 16th, far from down and out.

Thomas Tuchel - Chelsea (September 7)

Arguably the biggest shock sacking of the season came early on, when Tuchel was shown the door by Chelsea's new owners. Not long over a year on from leading the Blues to Champions League success, Tuchel was out of work. He is now back in a job, having succeeded Julian Nagelsmann at Bayern Munich in March.

Graham Potter - Brighton and Hove Albion to Chelsea (September 8)

Potter will feature again in this list, of course, but he does count as two of the 13 departures on Opta's list, given he left Brighton to fill the Chelsea vacancy. The Seagulls had enjoyed a brilliant start to the season and Potter had earned his shot at a big club. It would not, of course, go according to plan.

Bruno Lage - Wolves (October 2)

A full month had not passed by the time a third coach was given the boot. Lage had a decent first season at Wolves, but their form had tailed off towards the back end of the 2021-22 campaign, going winless in seven games. That poor form carried into this term, and having won just one of their first eight league games, Wolves decided to make a change.

Steven Gerrard - Aston Villa (October 20)

Gerrard made a bright start at Villa in 2021, and had been given a large transfer budget across two windows, but the former Rangers boss was struggling to make matters click, either with his team or the fanbase. Villa made the call to end the project before the World Cup, and moved efficiently to bring in Unai Emery, who has got them well clear of any danger. Since his first game in charge, only Arsenal (13) and Manchester City (10) have more Premier League wins than Villa.

Ralph Hasenhuttl - Southampton (November 7)

Hasenhuttl had provided Southampton with fresh life when he was appointed in 2018, but since reaching a pinnacle of topping the table in November of the 2020-21 season, it had been a constant struggle. Saints managed to scrape 40 points last season but were firmly in the relegation scrap when they decided time was up for the Austrian. His replacement, however, did not fare well.

Frank Lampard - Everton (January 23)

That glut of changes prior to the World Cup break was followed by the halting of Lampard's Everton tenure in late January. Results had been terrible, with Lampard managing just three wins all season - a tally already matched by his successor Sean Dyche. However, the nature of dismissing a manager so late in the transfer window left Everton with little time to reinforce their squad, and they are still firmly in the mire. Losses to Wolves, Brighton, Southampton and West Ham marked the end of Lampard's time at Goodison Park.

Jess Marsch - Leeds United (February 6)

After one relegation candidate blinked, so did another. Marsch was ditched by Leeds following a 1-0 defeat to Nottingham Forest, with the Whites - like Everton - once again faced with a scrap for their lives. Marsch, like Lampard on Merseyside, had managed to garner enough spirit and resolve to keep Leeds in the division last season, but the American was not an entirely popular figure among Leeds' fanbase, and whatever system he was trying to implement was clearly not working.

Nathan Jones - Southampton (February 12)

To put it frankly, Jones' time at St Mary's Stadium was downright bizarre. Brought in from Luton Town, Jones clearly had no lack of self-belief, but he lost his first four league games at the helm. Southampton appeared to be clicking into gear under Jones when they beat Crystal Palace in the FA Cup, Manchester City in the EFL Cup and then Everton in the league, yet the Weslhman – who was not shy at reeling off his strengths despite the lack of results – received his marching orders following the EFL Cup semi-final loss to Newcastle United and a 3-0 top-flight defeat to Brentford, with Saints bottom of the pile, where they remain.

Patrick Vieira - Crystal Palace (March 17)

A run of 13 games in all competitions without a win led to Vieira getting the boot midway through March. Palace lost 4-1 to league leaders Arsenal under the interim charge of Paddy McCarthy, and turned to former, supposedly retired, boss Roy Hodgson to try and push them away from danger. Hodgson made a good start, with the Eagles coming from behind to beat Leicester 2-1 on Saturday.

Antonio Conte - Tottenham (March 26)

An unhappy marriage came to an end when Conte left Spurs by mutual consent, just over a week on from lambasting his "selfish" squad, along with the entire club's mentality, following a 3-3 draw at Southampton. Conte had never seemed content at Tottenham, and now Cristian Stellini will oversee the rest of the season. The international break was a turbulent one for Spurs, with director of football Fabio Paratici now on a leave of absence after his ban from Italian football was made a worldwide one by FIFA last week.

Brendan Rodgers - Leicester City (April 2)

Leicester played the April fools on Saturday in their defeat at Selhurst Park, a result that left them in the relegation zone. Rodgers had earned the Foxes' backing with his achievements since taking over in 2019, having won the FA Cup and led Leicester into Europe twice. However, Leicester had won just two league games since the season restarted, and a change felt overdue.

Graham Potter - Chelsea (April 2)

Not long after the dust had settled on Rodgers' departure, Chelsea confirmed the news that Potter was no more. Well, not literally, but the man who had managed so much magic with Brighton could not replicate those tricks at Stamford Bridge. A three-game winning streak in March seemed to suggest a turnaround was in the offing, but a home draw with Everton and Saturday's 2-0 loss to Villa marked the end for Potter, who will perhaps regret leaving Brighton. He leaves Chelsea with the joint-lowest points-per-game total of any of the Blues' Premier League coaches (1.27).

Manchester United have been charged by the Football Association (FA) for their players' behaviour towards the referee during Sunday's 3-1 FA Cup quarter-final win over Fulham.

Wolves have also been charged for a similar incident in their 4-2 home defeat to Leeds United in the Premier League on Saturday.

United's game against Fulham at Old Trafford took a spectacular turn in the second half when Willian was sent off for the visitors for blocking Jadon Sancho's goalbound shot with his arm, which led to furious reactions from Aleksandar Mitrovic and head coach Marco Silva, who also received red cards.

Mitrovic put his hands on referee Chris Kavanagh, and the FA confirmed that both had been charged, but added that "that standard punishment which would otherwise apply to Aleksandar Mitrovic for the sending off offence of violent conduct that he committed towards the match referee is clearly insufficient."

United's players also surrounded the referee during the incident and the club have been charged with failing to ensure their players "conducted themselves in an orderly fashion and/or do not behave in a way which is improper."

Meanwhile, Wolves' players and staff were incensed by the decision to award Leeds' fourth goal at Molineux after they felt Adama Traore had been fouled in the build-up.

The fallout led to substitute Matheus Nunes being shown a red card for his reaction, though that was later overturned on appeal.

Wolves have been charged with failing to ensure their players "and/or technical area occupants do not behave in a way which is improper towards an assistant referee and the fourth official."

Both clubs have until Monday to respond.

Chelsea seem to have resigned themselves to making a major loss on Romelu Lukaku, who has only netted five times on loan at Inter this term.

According to a Football Insider report, the Blues are ready to move him on in at the end of the season, with Inter unlikely to try to extend his stay in Milan.

Chelsea spent £97.5milion to bring Lukaku back to Stamford Bridge in August 2021, but they are unlikely to get anywhere near that now.

TOP STORY – GERMAN CHAMPIONS LINE UP SHOCK LUKAKU MOVE

Bayern Munich are lining up a shock move for Chelsea's Romelu Lukaku to bolster their attacking options, claims Fichajes.

The report claims Bayern boss Julian Nagelsmann is an admirer of the Belgium striker, who he believes is one of the world's best forwards if injury free.

Bayern will not commence negotiations with Chelsea until the end of the season. The German champions had been linked with Harry Kane as they look for someone to replace Robert Lewandowski, who left for Barcelona last year.

Calciomercato reports that Chelsea may try to land a deal with Roma with a swap deal involving Tammy Abraham.

ROUND-UP

– 90min claims Manchester City have reignited their interest in signing 19-year-old Bayer Leverkusen midfielder Florian Wirtz following a long-term knee injury which forced him to miss the 2022 World Cup. Fabrizio Romano claims Real Madrid will compete for the German's services too.

– Tottenham are interested in Manchester United goalkeeper Dean Henderson, reports ESPN. Henderson is currently on loan at Nottingham Forest from United, who could use Spurs' interest as leverage in a deal for Harry Kane, per the report

– Leeds United forward Wilfried Gnonto is drawing interest from Arsenal, Chelsea and Manchester City, according to Gazzetta dello Sport, while 90min claims Juventus and Napoli are among a list of Italian clubs tracking him too.

– Fabrizio Romano claims Barcelona on the cusp of agreeing to a deal with Athletic Bilbao centre-back Inigo Martinez to join the Blaugrana on a free transfer in the off-season.

– Paris Saint-Germain are prepared to let Portuguese midfielder Renato Sanches exit amid interest from Milan along with Premier League clubs Aston Villa, Liverpool, Newcastle United, Tottenham and Wolves, reports 90min.

– Football London reports Arsenal are ready to ramp up their interest in Real Sociedad midfielder Martin Zubimendi with a bid to come in the coming months, although he has a €60m release clause in his contract.

Wolves will have Matheus Nunes available for their next three matches after their appeal to the Football Association (FA) was upheld.

Nunes, an unused substitute, was sent off late on in Wolves' 4-2 home defeat to fellow strugglers Leeds United on Saturday.

The Portugal international had been remonstrating with the officials over the decision to allow Leeds' fourth goal, scored by Rodrigo, to stand despite what appeared to be a foul by Marc Roca in the build-up.

Julen Lopetegui confirmed Nunes was complaining about the linesman and that they would appeal the decision, with referee Michael Salisbury having incorrectly sent the midfielder off for violent conduct, which would have resulted in him missing games against Nottingham Forest, Chelsea and Brentford.

Wolves will be without Jonny, however, after the defender was sent off for a lunge on Luke Ayling.

The defeat left Wolves in 13th place in the Premier League, one point above Leeds and just three clear of the relegation zone.

Lopetegui thought his side were hard done by, with the former Spain coach claiming Wolves should have had a penalty.

"I'm not waiting for [further apologies]. I just want them [the officials] to do their job," he said.

Leeds United, Everton, Southampton and Leicester City all earned big results on Saturday in their efforts to beat the drop.

The Premier League's struggling sides were the big winners from the five matches to take place.

Leeds beat fellow relegation candidates Wolves 4-2, while Everton pegged back Chelsea twice at Stamford Bridge and Southampton came from 3-1 down to draw 3-3 with Tottenham.

Leicester, meanwhile, snatched a draw at Brentford, though 19th-placed Bournemouth lost 3-0 at Aston Villa.

Wolves 2-4 Leeds United: Six-goal thriller and two reds at Molineux

Leeds came out on top in an enthralling encounter at Molineux, with Javi Gracia's side claiming what could be a vital three points in their bid to survive this season.

Jack Harrison put them ahead early on, and he has now been directly involved in four goals (two goals, two assists) in his four Premier League games under Gracia, just one fewer than in his previous 21 matches under Jesse Marsch and Michael Skubala this season (five).

Luke Ayling netted his first league goal since doing so against Wolves exactly a year ago (March 18, 2022) to make it 2-0, with Rasmus Kristensen putting Leeds three ahead.

Their hopes of a comfortable win were dashed when Illan Meslier, on the day he became the youngest goalkeeper in Premier League history to reach 100 appearances, made a mistake that Jonny pounced on, volleying in from 41 yards. That is the furthest distance a player has scored from in the top flight since Wayne Rooney's 58-yard strike for Everton against West Ham in November 2017.

A deflected Matheus Cunha strike gave Wolves hope, but Jonny became the first Wolves player to both score and be sent off in any league game since September 2008. 

Julen Lopetegui was fuming that Wolves were not awarded a first-half penalty and that a foul was not given in the build-up to Rodrigo's late effort for Leeds, with Matheus Nunes then sent off even though he was on the substitutes' bench.

"I'm not waiting for [further apologies]. I just want them [the officials] to do their job," Lopetegui said.

Southampton 3-3 Tottenham: Conte left seething after Ward-Prowse seals comeback

Southampton came from two goals down to avoid defeat for a second time in the Premier League this season, with only Manchester City (P3 W2 D1) avoiding defeat having fallen two goals behind on more occasions this term.

Tottenham, who took the lead through Pedro Porro but saw it cancelled out by Che Adams, restored their advantage through Harry Kane – he has now scored nine headers in the league this season, equalling Duncan Ferguson's single-season record in the competition from 1997-98.

Ivan Perisic took Spurs' tally of Premier League scorers to 162, with only West Ham (164) having more different scorers in the competition's history, yet Theo Walcott pulled one back for Saints. The former Arsenal winger has more top-flight goal involvements (12) and goals (seven) against Tottenham than he does against any other opponent.

Yet Spurs conceded a 14th goal since the season restarted when Pape Sarr was deemed to have fouled Ainsley Maitland-Niles, and James Ward-Prowse converted the penalty. He has been involved in more Premier League goals against Tottenham than he has any other opponent (nine – five goals, four assists).

Brentford 1-1 Leicester City: Barnes holds the Bees

Brentford remain without a win against Leicester in the Premier League (P4 D2 L2). The Bees have not beaten the Foxes in the league since March 1953 (P8 D3 L5 since).

Leicester ended a run of four consecutive defeats in the Premier League but this was just the eighth point they have picked up in 2023 (P10 W2 D2 L6). Only Crystal Palace (five) have picked up fewer points since the turn of the year, while only Everton and Bournemouth (20 and 18 respectively) have conceded more goals in the competition this calendar year than Leicester's 17.

Only Ivan Toney (eight) has scored more home goals for Brentford in the Premier League this season than Mathias Jensen (five), whose goal was the Bees' 19th from a set-piece this term – more than any other side in the division.

Leicester scored from their only shot on target of the game. Harvey Barnes' goal was his ninth of the season – his joint-most in a single Premier League campaign (also nine in 2020-21).

Chelsea 2-2 Everton: Simms snatches huge point

Substitute Ellis Simms scored his first goal for Everton as Sean Dyche's team drew 2-2 at Stamford Bridge, twice coming from behind.

Chelsea are unbeaten in their last 28 Premier League home games against Everton (W15 D13), but the Toffees can take plenty of confidence from this result.

Joao Felix put Chelsea ahead with his first home goal for the Blues, but Abdoulaye Doucoure equalised from a corner; four of Everton's seven goals under Dyche have come from set-pieces.

Kai Havertz converted a spot-kick to restore Chelsea's lead. He has scored in three consecutive games for the Blues for the second time, previously doing so in March 2022.

However, Simms came on from the bench to earn a point for Everton. The Toffees have now had 13 different goalscorers in the competition this season, with only Arsenal, Chelsea and Leeds (14 each) having more.

Arsenal crashed out of the Europa League with a penalty shoot-out defeat to Sporting CP on Thursday, and Mikel Arteta will be looking for an instant response in the Premier League.

The title is now their sole focus, and with Manchester City in FA Cup action this weekend, the Gunners can move eight points clear at the top should they beat Crystal Palace, who on Friday sacked Arsenal great Patrick Vieira after an 11-game winless run.

Palace are 12th but only three points above the relegation zone, and that picture could change by the time they play on Sunday.

After Nottingham Forest welcome Newcastle United on Friday, Bournemouth visit Aston Villa, Leicester City have a tough trip to Brentford, Southampton host Tottenham, and Wolves and Leeds United face off in another big match at the bottom of the table. Everton, who are also in the relegation scrap, play Chelsea at Stamford Bridge.

Here, with the help of Opta data, Stats Perform has provided some key insights and predictions.

Southampton v Tottenham 

Between December 2019 and January 2021, Southampton won five of six Premier League games against sides starting the day in the top four of the table (L1). However, since then they are winless in 15 such games (D6 L9), conceding 43 goals and scoring just nine in return.

Southampton have scored at least once in each of their last 14 Premier League games against Spurs, since a 2-0 home loss in December 2015, but they have kept just one clean sheet in their last 21 against them, when they won 1-0 in January 2020.

In all competitions, Tottenham have lost each of their last four away games, the last three of which without scoring. This is Spurs' longest run of away defeats in succession since May 2019 (five in a row), while not since January 1983 have they lost four straight away matches without scoring (a run of five).

Best bet – Harry Kane to score or assist: Harry Kane has been directly involved in 17 goals in 15 Premier League appearances against Southampton (11 goals, six assists), having only had a hand in more goals against Leicester (22). The England captain has scored nine away goals in the competition this season – no other player in Premier League history has netted 10 times on the road in more than four separate campaigns, whereas Kane is on the verge of doing so for the seventh time.

Long shot – Richarlison to score: Richarlison was desperately unlucky not to break his duck for Spurs in the win over Forest last week, with a fierce finish ruled out for offside. The Brazil forward has netted five times in his last seven league appearances against Saints, making them his favourite team to play against when it comes to goals, but he is yet to score in the Premier League this season.

Opta prediction: Spurs are made favourites for this one by Opta's supercomputer, with Antonio Conte's team given a 54 per cent chance of victory. There is roughly a one in four chance of a draw (25.7 per cent), while Southampton, who prop up the table but could move as high as 15th with a win, are given a 20.3 per cent chance of claiming the spoils.

Wolves v Leeds United

Having been unbeaten in six league games against Leeds between 2017 and 2021 (W5 D1), Wolves have lost their last two against the Whites. Indeed, Leeds are looking to complete their first league double over Wolves since 2015-16 and their first in the top flight since 1973-74.

Leeds, who will be without key midfielder Tyler Adams due to a hamstring issue, have earned four points from their three Premier League games under Javi Gracia (W1 D1 L1), as many as they had in their 10 games before his arrival (W0 D4 L6). However, they are winless in their last seven away matches (D2 L5). 

Wolves boss Julen Lopetegui has won both of his previous meetings with Gracia in all competitions. These games came in the 2020-21 campaign, with Lopetegui's Sevilla beating Gracia's Valencia 1-0 in LaLiga and 3-0 in the Copa Del Rey.

Best bet – Wolves to avoid defeat: No side have fewer away wins (one) or away points (six) in the Premier League this season than Leeds, who have lost nine of their 13 away league games this term. Wolves, meanwhile, have won three of their last four home league games (L1), more than they had in their previous 12 (W2 D3 L7). 

Long shot – Wolves to score over two goals: Wolves have a shot conversion rate of 6.8 per cent in the Premier League this season, their lowest in any of their nine campaigns in the competition. Only once have they scored more than twice in a top-flight game this term, when they beat Liverpool 3-0 in February.

Opta prediction: Expect this one to be close, based on the prediction model, which makes Wolves the slight favourites (39.3 per cent), although Leeds are at 31.3 per cent. A draw is certainly feasible and is given a 29.4 per cent chance.

Chelsea v Everton

Chelsea are unbeaten in their last 27 Premier League home games against Everton (W15 D12) since a 1-0 loss in November 1994. Against no side have they ever had a longer unbeaten run at Stamford Bridge in their top-flight history. Everton managed a 1-1 draw with a makeshift side in the corresponding fixture last season, but a win still evades them.

Before this season, Everton had beaten Chelsea in each of the last four Premier League campaigns, although all of their victories were at home. They have not beaten the Blues in five straight league seasons since the 1930s.

Everton have won three of their seven Premier League games under Sean Dyche so far (D1 L3), as many as they had in their 20 matches under Frank Lampard this season (D6 L11), but again all of those wins have come at home.

Best bet – Chelsea to win: Everton are winless in their last 11 Premier League away games against London sides (D3 L8), failing to score in each of the last four, and Chelsea have only failed to beat the Toffees at home twice since the start of the 2016-17 season.

Long shot – Everton to win 1-0: If the visitors are to claim a victory, expect it to be a cagey one. In fact, 40 per cent (30) of Dyche's 75 Premier League wins have been by a 1-0 scoreline, including his three as Everton boss. Of the 52 managers with at least 50 wins in the competition, only Tony Pulis (42 per cent – 41 of 98) has won a higher share by a 1-0 scoreline.

Opta prediction: Given Everton's torrid form on the road – they have won fewer Premier League away games (three) and earned fewer points on the road (18) than any of the 17 ever-present sides since the start of last season – and dismal record at Stamford Bridge, Chelsea are the overwhelming favourites at 54.1 per cent on Opta's model. Everton are handed a slim 19.3 per cent chance of success, while the draw is rated at 26.6 per cent.

Arsenal v Crystal Palace 

Palace elected to part ways with Arsenal legend Vieira and could well be further embroiled in the relegation battle by the end of Sunday's game. After all, the Gunners have won their last five Premier League matches, netting at least three goals in four of those, including each of the last three. 

Arsenal have won eight of their nine London derbies in the Premier League this season (D1); in English Football League history, no side have ever won nine all-London match-ups in a single season. Palace, on the other hand, have won just one of their eight derbies this term. The Eagles have, however, avoided defeat in their last four Premier League away games against Arsenal, with each of the last three ending level (W1).

Since his Premier League debut for Arsenal in January, no player has been involved in more goals for the Gunners than Leandro Trossard (six – one goal, five assists). He has five assists in his last four Premier League games, as many as in his previous 64 appearances.

Best bet – Gabriel Martinelli to have 2+ shots on target: After missing the crucial penalty in Arsenal's shoot-out loss to Sporting in Europe, Martinelli will be determined to put things right. He is Arsenal's highest goalscorer in the Premier League this season with 12 goals, including five in his last five appearances. 

Long shot – Palace to keep a clean sheet: Palace have kept just one clean sheet in 22 away league games against Arsenal (49 goals conceded), a goalless draw in January 2021, while the Gunners have scored in all but one of their league games at Emirates Stadium this season.

Opta prediction: Arsenal are the favourites, although given the respective form of these sides, a 54.6 per cent win prediction perhaps feels a bit low – a reflection of Palace's recent unbeaten run at Emirates Stadium. Opta gives the draw a 26.5 per cent chance, while the supercomputer has a Palace win ranked at 18.9 per cent.

Julen Lopetegui claimed Wolves were denied a "very, very clear penalty" by referee Andy Madley in Sunday's 2-1 defeat at Newcastle United.

Wolves were furious in January when they had a late goal disallowed for offside against Liverpool in the FA Cup at Anfield, and they remain convinced that was an injustice.

Madley was also the man in the middle that time, with Wolves denied what would almost certainly have been a winning goal as the game finished 2-2, with Liverpool going on to edge the replay 1-0 at Molineux.

That incident has not been forgotten by Lopetegui, and he was aghast at Wolves being denied a spot-kick early on against Newcastle at St James' Park.

Newcastle goalkeeper Nick Pope took a poor touch and gave away the ball to Wolves striker Raul Jimenez, before seeming to bundle the Mexican to the floor.

Wolves wanted a penalty and a red card but got neither, and Lopetegui said afterwards: "It's true that, for me, it was a very, very clear penalty for us. We are very unlucky with the referee. This is a pity for us.

"It doesn't matter what I think. The more important thing is that this is true that we have suffered a big mistake a lot of matches ago at Liverpool, and for me [Sunday's incident] was a penalty, but the VAR can't help in this case the referee. We were very unlucky with the decision. We didn't have a penalty since I arrived here."

Alexander Isak headed Newcastle ahead in the first half, but Hwang Hee-chan brought Wolves level in the 70th minute.

The visitors sat deep and were punished by a fine finish from Miguel Almiron nine minutes later.

Newcastle head coach Eddie Howe told Sky Sports he felt there would have been no justification in awarding Wolves a penalty for the clash between Pope and Jimenez, which came when the game was goalless.

Howe said: "I didn't think it was a penalty at the time. You might say I was biassed, but I didn't. I thought it was Jimenez going down before the contact was made, that was my initial assessment."

Substitute Almiron delighted Howe with his contribution off the bench, having been a regular starter up to now.

"Not that he necessarily needed to give a response, it was a case of us just trying to freshen him up," Howe said. "It's an outstanding season that he's had, he's contributed in lots of different ways, and you see the work rate he gives every week. He made a massive impact, and I'm delighted for him."

Howe was glad to halt a five-game winless run, with the Magpies jumping above Liverpool into fifth place.

"I just think it reignites us," he said. "Hopefully it re-sparks us into action and restores confidence levels to where they should be."

Leandro Trossard and Casemiro were two of the standout players in Sunday's Premier League action – though for contrasting reasons.

Belgium international Trossard was inspirational as Arsenal's title tilt remained on track, while Casemiro was shown a second red card in three Premier League appearances as Manchester United slipped up again.

Miguel Almiron was Newcastle United's hero, Eddie Howe's men closing on the Champions League places again, and Ollie Watkins continued his fine form for Aston Villa in their draw with West Ham.

After the conclusion of the day's drama, Stats Perform highlights the pick of the Opta numbers.

Manchester United 0-0 Southampton: Another Casemiro red threatens to derail Ten Hag's men

Casemiro has undoubtedly been one of United's best players this season, but if they now miss out on the top four, the Brazil international will have to take part of the blame.

His sending off in the first half on Sunday for a heavy challenge on Carlos Alcaraz proved costly, with United only able to scrape a point thereafter.

That made him the first United player to receive two red cards in one Premier League season since Nemanja Vidic in 2013-14, and just the second to earn a pair of reds in his first campaign for the club after Darren Fletcher (2003-04).

He will now miss their next four matches – at the end of that run, he will have been suspended for eight games this year alone.

While some United fans might have had the perception this was always going to be the risk that came with signing a player like Casemiro, he had never been shown a straight red in his entire senior career before moving to Old Trafford.

Of course, for Southampton, Casemiro's dismissal proved helpful. While they could not get the win they might feel they deserved, Saints managed to keep a third clean sheet in four games under Ruben Selles – that is one more than in their previous 34 league games.

Fulham 0-3 Arsenal: Trossard inspirational as Gunners continue to deal out capital punishment

Arsenal's comprehensive win at Craven Cottage was their fifth successive away London derby win without conceding a goal.

That is a feat no club has managed previously in the Premier League.

Trossard played a vital role with a unique feat of his own, setting up all three of Arsenal's goals, with each one coming in the first half.

Thus, the Belgian became the first player to ever tally a hat-trick of assists in the first half of a Premier League away game.

Trossard's second was a looping cross that found Gabriel Martinelli for a close-range header, the Brazilian nodding in his 23rd top-flight goal for the club.

He is now only one away from surpassing Nicolas Anelka as the foreign player with the most Premier League strikes for the club before turning 22.

That first-half flurry keeps the Gunners on track in the title race, five points clear of Manchester City in second.

West Ham 1-1 Aston Villa: Watkins in a groove

Unai Emery has certainly managed to steady the ship at Aston Villa since replacing Steven Gerrard in the dugout, and the form of Watkins has been among the most notable improvements.

The striker netted again on Sunday, opening the scoring at London Stadium as he headed in from Alex Moreno's cross.

Since the World Cup, only Marcus Rashford (10), Erling Haaland (10) and Harry Kane (eight) have scored more Premier League goals than Watkins (seven).

That includes goals in each of his past four Premier League away games, which is the longest such scoring run by a Villa player since Dwight Yorke between March and May 1998 (also four).

Unfortunately for Villa, West Ham levelled just nine minutes later through Said Benrahma, who was lively throughout.

His penalty continued his 100 per cent record from the spot in English league football, with that his third from three for West Ham having also converted 4/4 at Brentford.

Over the course of the 90 minutes, Benrahma had 10 shots, which is the joint-most on record (since the 2003-04 season) for a West Ham player in a single Premier League game.

He could not single-handedly inspire a turnaround, however.

Newcastle United 2-1 Wolves: Almiron comes up trumps yet again

Almiron has stepped up this season, becoming a key player for Newcastle and a regular source of goals.

A recent dip in form saw him dropped from the starting XI for the visit of Wolves on Sunday, but he responded well.

Eleven minutes after his second-half introduction, he found space in the right side of the box and saw a deflected effort beat Jose Sa following Joe Willock's well-timed pass.

That was his fourth winning goal of the season – the most among Newcastle players – and his 11th goal in total in the Premier League, which is four than his previous four campaigns combined.

Earlier, Hwang Hee-chan had equalised just 57 seconds after coming off the bench, making it the second-fastest substitute goal of the season.

But the day belonged to Almiron as Newcastle ended a five-match winless streak.

Harry Kane has rallied his Tottenham team-mates, calling on them to make the most of the rest of the Premier League season as they aim for the top four.

Spurs slipped to a defeat against Wolves on Saturday, with Adama Traore's late strike snatching a 1-0 victory for the hosts at Molineux.

It saw Tottenham, in what is set to be their final game under temporary boss Cristian Stellini before Antonio Conte returns from his enforced lay-off, fail to build on the four-point cushion over fifth-place Newcastle United, who lost 2-0 at Manchester City.

Coupled with a shock FA Cup exit to Championship side Sheffield United on Wednesday, Kane acknowledged it has been a tough spell, but the England captain backed his team-mates to turn Spurs' fortunes around.

"It's been tough, a really disappointing week," he said. "All we can do is look forward now. We have 12 or 13 games now to push for that top-four place.

"The games come around quick, and we have to look to the next one. If we had won today, we would've been in a good spot with the last third of the season to play.

"[But] there's still going to be points dropped, and we need to concentrate on ourselves and finish as strong as possible."

Stellini, meanwhile, has overseen a tepid end to his interim time at the helm, and he knows Spurs must be at their best in order to translate their performances into crucial results.

"It was a good performance. We started well in the game," Stellini told Sky Sports. "We had chances to score and we could've killed the game. 

"It was a tough game like we expected but we were ready to challenge, to fight, to play a great game. We missed some chances in the first half and maybe it could've been a bit different."

Of the tussle for Champions League qualification, Stellini added: "It will be a tough race. We are not alone with Newcastle, other teams will arrive. We have to be ready to play these type of games again.

"Maybe we have to have more of the killer instinct, to kill the game when you have the possibility to do [so]. In the first half, it was really under control, and we needed to kill it."

Adama Traore's late strike saw Tottenham stunned by Wolves in the Premier League on Saturday, as the north London side slipped to a 1-0 defeat at Molineux.

The Spain international netted in the 82nd minute, crashing his finish in off the crossbar after Fraser Forster had parried Raul Jimenez's shot towards him.

Traore's goal condemned the visitors to back-to-back defeats under temporary boss Cristian Stellini, after their shock FA Cup exit to Sheffield United on Wednesday.

But while Antonio Conte will return to a side in disarray, opposite number Julen Lopetegui will delight in a big result that provides a major boost to his team's top-flight survival bid. 

Lionel Messi, Kylian Mbappe and Neymar were a joy to play alongside but Pablo Sarabia nevertheless wanted to leave Paris Saint-Germain.

Sarabia swapped hopes of a Ligue 1 title and push for Champions League glory with PSG for a relegation battle in the Premier League with Wolves in January.

The Spain international reunited with Julen Lopetegui, who he had previously worked under in La Roja's under-21s team.

Lopetegui has lifted Wolves off the bottom of the table and out of the relegation zone, though ahead of Saturday's meeting with Tottenham they have failed to win their last three games.

Sarabia is enjoying life in England, however, despite no longer playing alongside three of the world's best players.

In an interview with The Telegraph, the 30-year-old said: "It was amazing to play with Messi, Mbappe and Neymar.

"It was a very good experience, but for me the most crucial thing is to feel important in the team."

Sarabia also suggested the unity at Wolves is greater than that of PSG, adding: "I prefer to play in another team to feel that unity, to be part of it, to be a member of the team and of a family, rather than just an addition of individuals.

"I was not happy not to play. It's very difficult to play considering the level of PSG players, so I made the decision to come here. In my career I have been through a lot of difficult moments, but now I want to enjoy it.

"I feel that at this moment, I'm in the prime of my career."

Sarabia has scored once in six league appearances for Wolves, with five of those coming as starts.

He started only three Ligue 1 games for PSG this term prior to his January transfer, having spent last season on loan at Sporting CP, where he netted 21 goals.