Italy will miss out on a second successive World Cup after Aleksandar Trajkovski's stoppage-time strike gave North Macedonia a sensational 1-0 victory at Renzo Barbera.

Having also failed to qualify for the 2018 tournament in Russia, the European champions will not go for glory in Qatar this year after suffering their first World Cup qualifying defeat on home soil.

Roberto Mancini's side dominated the game, but they were made to pay for their lack of a cutting edge in a dramatic finale.

Trajkovski was North Macedonia’s hero, beating Gianluigi Donnarumma from 25 years in the second minute of stoppage time set up a showdown with Portugal for a place in the World Cup.

UK Prime Minister Boris Johnson has dismissed the notion of Russia hosting Euro 2028 as "beyond satire", instead suggesting the tournament be awarded to Ukraine.

Russia launched a bid for either Euro 2028 or Euro 2032 on Wednesday, despite the country's ongoing invasion of their Eastern European neighbour.

That puts the 2018 World Cup hosts against a joint United Kingdom and Republic of Ireland bid for the former, an Italy bid for the latter and a Turkey bid for either event.

"The idea of Russia holding any idea of football tournament or any kind of cultural event right now is beyond satire," Johnson said in Brussels, where a Nato summit addressing Vladimir Putin's invasion is taking place.

"I can’t believe that anybody would seriously consider their suggestion."

Johnson appeared to forget that his own country had bid for Euro 2028 when he subsequently suggested the best path would be to hand it to Ukraine, who jointly hosted Euro 2012 with Poland.

"I think the best thing possible would be for the entire Russian forces to retire forthwith from Ukraine and hand the tournament to them," Johnson added.

Last year's rearranged Pan-European edition saw Italy triumph over England in a penalty shoot-out final at Wembley Stadium.

Hosts will be confirmed for 2028 and 2032 in September 2023, ahead of the next edition in Germany in 2024.

Roberto Mancini says Italy will not look beyond Thursday's play-off semi-final with North Macedonia as they aim to avoid more World Cup qualifying heartbreak.

Italy, then under the management of Gian Piero Ventura, failed to qualify for the last World Cup for the first time since 1958 after losing to Sweden in the play-offs.

The Azzurri bounced back from that disappointment by winning the European Championships last year for only the second time.

Just eight months on from that triumph, Mancini's men are once again relying on the play-offs to help them reach Qatar 2022 after finishing behind Switzerland in their group.

Should Italy overcome North Macedonia in Palermo, they then face a showdown with either Portugal or Turkey – who meet in Porto on Thursday – in next week's final.

Italy are strong favourites to beat North Macedonia, who are 61 places below their opponents in the FIFA rankings, but Mancini does not consider his side favourites.

"We all start the same; each game is 0-0 and anything can happen in those 90 minutes," he said at Wednesday's pre-match news conference.

"It's an obvious thing to say, but you have to play each game. I don't think there are favourites in these matches.

"North Macedonia defend well and have good technique. Don't forget they won away to Germany in the qualifiers. We need patience, but it starts from 0-0."

A large core of Italy's current contingent were also part of the squad that missed out on a place at Russia 2018, but Mancini is unsure if that works in his side's favour.

"I don't know if it can act as an advantage," he said. "This is part of the life of a sportsman. There are exciting moments in your career and others of disappointment.

"We just have to be focused on what we have to do. Italy know how to play football and we have to just think about ourselves, not other things."

UEFA has confirmed it received declarations of interest from four potential bidders for hosting rights to Euro 2028 and Euro 2032.

The United Kingdom and Republic of Ireland launched a joint-bid for Euro 2028 earlier on Wednesday, while a Russian official remarkably confirmed its own interest in holding either of the two tournaments.

Russia's teams are currently banned from UEFA and FIFA competitions following the country's invasion of Ukraine, but the 2018 World Cup hosts pushed ahead regardless.

Turkey has joined Russia in announcing to UEFA its willingness to stage the European Championship in either 2028 or 2032.

While the two countries are up against the UK and Ireland in the first of the two finals, Italy is the other interested party four years later.

The hosts of the two tournaments will be announced in September 2023.

Will it be Mohamed Salah or Sadio Mane? Italy or Portugal – or indeed neither? Can Canada end their long wait, and are the United States and Australia at risk of missing out?

Those questions and plenty more are set to be answered over the next week or so as World Cup qualifying concludes for many nations.

Just 15 of the 32 participants have so far been confirmed for Qatar 2022, leaving 48 teams battling for the 17 remaining spots.

Fourteen more countries will be assured of a finals berth come the end of next week in what is very much crunch time for those still in contention.

Stats Perform looks at the key talking points.

Egypt seeking revenge in AFCON final repeat

Less than two months on from meeting in the Africa Cup of Nations final, Egypt and Senegal face off over two legs for a place in Qatar.

Senegal prevailed in a penalty shoot-out to claim their first AFCON crown and, buoyed by that triumph, will consider themselves as favourites here.

While both teams boast an array of top-class talent, this fixture is being billed as a showdown between Liverpool team-mates Salah and Mane.

The two biggest stars in African football, only one of the pair will be part of the World Cup later this year – and neither will fancy watching it all unfold from home.

This is not the only grudge match taking place in the CAF section over the next week and a half, as fierce rivals Ghana and Nigeria will also face off in a two-legged play-off.

Cameroon are up against Algeria, Mali take on Tunisia and DR Congo meet Morocco in the other three ties, each of which will be concluded on March 29.

European heavyweights on collision course

Since the play-off draw in the UEFA section took place in November, all talk has centered around a potential meeting between Italy and Portugal for a place in the finals.

The winners of the past two European Championships, either the Azzurri or the Selecao will miss out on the biggest tournament of them all.

It should never have been this way, of course, as both teams were strong favourites to finish top of their groups and qualify automatically.

Italy finished second to Switzerland and Portugal were runners-up to Serbia, meaning the sides must now come through two qualifying ties.

First up for the reigning European champions is a meeting with North Macedonia in Palermo, while Portugal face Turkey in Porto, with the winners of both ties advancing.

Should, as expected, Italy and Portugal come through those semi-finals, the latter will have the advantage of staging the final on home soil five days later.

For Portugal skipper Cristiano Ronaldo, it presents what will surely be his last chance to play at a record-equalling fifth World Cup.

Pathways impacted by political events

Path C of UEFA qualifying is undoubtedly the most eye-catching, but there are also some tasty fixtures in the other two sections – not least a possible Home Nations derby.

Scotland and Wales were kept apart in the Path B semi-finals but could meet in the final should they overcome Ukraine and Austria respectively.

However, due to ongoing events in Ukraine, their game against Scotland has been pushed back – likely until June – as has the final involving either Wales or Austria.

In Path C, Russia had been due to face Poland, but the invasion of Ukraine forced FIFA and UEFA's hand and they have been banned from competing.

Poland have therefore been handed a bye to the qualifying play-off final, where either Sweden or the Czech Republic await. That match will be contested next week as planned.

Canada on verge of ending long wait, USA with work to do

The United States qualified for every World Cup between 1990 and 2014, but they missed out on a place at Russia 2018 after an embarrassing loss to Trinidad and Tobago.

Gregg Berhalter's side are by no means assured of one of the three automatic qualification spots in the CONCACAF section this time around, either.

USA sit second with three games to go, but they still have to travel to third-placed Mexico, as well as facing Panama and Costa Rica, who occupy fourth and fifth respectively.

Level on points with Mexico and four ahead of Costa Rica, it could be a tense finale to qualifying for the Stars and Stripes.

That should not be the case for Canada, who are eight points clear of fourth and are all but assured of ending their 36-year wait to make a second World Cup finals appearance.

Brazil and Argentina through, but who will join them?

The drawn-out South American qualifiers are nearing their conclusion and only four of the 10 sides know their fate at this juncture.

It has been plain sailing for Brazil and Argentina, who are assured of an automatic qualifying spot with three games to go, including a rescheduled meeting between the pair.

Behind those perennial World Cup representatives are Ecuador, who have been the surprise package in qualifying and can finish no lower than fifth.

Ecuador will not be content with anything other than a top-four finish, though, and they can make certain of that with victory over Paraguay.

Assuming Ecuador get over the line, that will leave Uruguay, Peru, Chile, Colombia and Bolivia battling it out for progression, which sets up some intriguing fixtures.

Uruguay occupy fourth place, meaning their qualifying aspirations are in their own hands, but they have Peru and Chile – the two sides behind them – still to face.

Socceroos sweating on finals spot

Only four teams advance automatically from the CONMEBOL section, with the team in fifth entering a play-off against the winner of the AFC fourth round in a one-off tie in June.

That may well turn out to be Australia as the Socceroos are five and four points behind top two Saudi Arabia and Japan in Group B with two games to go.

However, those remaining two fixtures are against those nations occupying automatic qualification places, so Australia may yet sneak through.

Iran and South Korea have already made certain of progression in Group A, meanwhile, leaving the United Arab Emirates, Lebanon and Iraq to compete for third place.

The two third-placed finishers – which, as it stands, are Australia and the UAE – will meet in a one-legged match ahead of that aforementioned play-off with a CONMEBOL side.

Italy were jolted ahead of the World Cup play-off against North Macedonia when two members of the Azzurri staff tested positive for COVID-19.

The European champions are bidding to qualify for the Qatar 2022 tournament, knowing a win over Thursday's opponents would see them go into a straight fight with Portugal or Turkey for a place in the finals next Tuesday.

Those have tested positive have gone into isolation.

Italy boss Roberto Mancini will hope there are no further cases detected at the Coverciano training base, particularly among his playing squad.

The identities of those who have tested positive have not yet been disclosed by the FIGC, Italy's football federation, which said targeted checks would continue.

A statement from the FIGC said: "During the preventive anti-COVID checks at the entrance to the national team meeting, two cases of COVID positivity were found among the members of the national team staff. The people were promptly isolated and re-entry was organised.

"Other positive cases relating to the organisational support staff to the national team emerged upon the arrival of the staff in Coverciano and, also in this case, the parties concerned were isolated and not admitted to the technical centre."

UEFA has confirmed that the game between Italy and Argentina to be played on Wednesday, June 1 in the first "Finalissima" in 29 years, will take place at Wembley Stadium.

The match was initially announced in September, with confirmation in December that a "renewed and extended Memorandum of Understanding (MoU) lasting until 30 June 2028" had been signed between UEFA and CONMEBOL, leading to a game to be played in London on June 1.

The original iteration, pitting the winner of the most recent European Championship against the winner of the most recent Copa America, was previously known as the Artemio Franchi Trophy and was held in 1985 and 1993.

France beat Uruguay 2-0 in the inaugural edition in 1985, while the 1993 game saw Argentina – led by Diego Maradona – beat Denmark in a penalty shoot-out.

As had been expected, the venue for this year's encounter has now been confirmed as Wembley, where the capacity will be 86,000 and tickets sold on a "first-come, first-served basis".

A statement from UEFA on Tuesday confirmed that: "[It] will give fans the chance to watch the current champions of the world's two best footballing continents contest the coveted CONMEBOL-UEFA Cup of Champions.

"Twenty-nine years after its last edition, the relaunch of this legendary footballing encounter is the result of the long-standing partnership between UEFA and CONMEBOL and will serve as a catalyst for the global development of football – uniting countries, continents, and cultures, while also demonstrating to fans around the globe that football can be a force of good in turbulent times."

Wembley holds fond memories for Italy as the venue of their Euro 2020 final victory over England last year.

Marco Verratti has come to the defence of his Paris Saint-Germain and Italy team-mate Gianluigi Donnarumma.

The goalkeeper came in for criticism following PSG's recent Champions League elimination at the hands of Real Madrid, in particular for his error that led to Karim Benzema scoring the Spanish side's first goal at the Santiago Bernabeu in an eventual 3-2 aggregate loss for the Parisians.

Donnarumma has conceded six goals in his last two club appearances, but ahead of Italy's World Cup qualifying play-off against North Macedonia, Verratti wants Azzurri fans to remember his performances during the run to winning Euro 2020.

"We need to be confident. Thursday will be an important match against a team that deserves to be here," Verratti told a news conference.

"As we did during the Euros, we have to go far with enthusiasm and desire.

"Each of us has different stories with our clubs, then here, we have to give everything. With the national team we have always managed to move forward."

It was put to the 29-year-old midfielder that players from PSG and Juventus who were knocked out of the Champions League could bring their dented confidence with them, and he was specifically asked about Donnarumma's mood.

"When you walk into Coverciano [Italy's training complex], you forget everything that happened before, the defeats with our clubs, and you remember what we did last year," Verratti retorted. "We are back to talking about the victory of the European Championship, it's different.

"He [Donnarumma] is sorry for his error against Real Madrid, but Gigio is a special guy. He was already back working the next day with the same enthusiasm.

"Let us not forget what he did for Italy during the Euros. He is one of the best goalkeepers in the world."

Donnarumma played seven games at the rescheduled tournament last year, making 10 stops at a save percentage of 71.43, conceding four goals and making key penalty saves from Jadon Sancho and Bukayo Saka in the final shoot-out against England to clinch the trophy at Wembley Stadium.

Italy are looking to make amends having failed to qualify for the 2018 World Cup, and Verratti insists they will "give everything" to get to Qatar.

"We are accustomed to playing under this kind of pressure," he said. "We know it's a very important moment and we cannot afford to be out of the World Cup, but the only thing I know is to work, give my best and do everything there is.

"When Roberto Mancini arrived [in 2018], we were a broken team and he took us to win the European Championship. He worked on our minds above all, now we are a completely different side and we will do everything to go to Qatar."

Italy head coach Roberto Mancini expressed his optimism for World Cup qualification as he called on his Euro 2020-winning side to prove the doubters wrong again.

The Azzurri failed to qualify for the 2018 World Cup but followed that up by winning the delayed European Championships last year.

Italy are now staring at a familiar fate, however, after not progressing through their World Cup qualifying group, leaving them having to beat North Macedonia in Thursday's play-off semi-final to keep their Qatar 2022 hopes alive.

Mancini's side would then have to negotiate past Cristiano Ronaldo's Portugal or Turkey in the final, but the former Manchester City boss spoke optimistically before the clash with North Macedonia in Palermo.

"We should not take the first game for granted. It won't be easy and, in case we win, we'll have four days to prepare for the final," he told reporters at a news conference on Monday.

"We have built a solid base, we are positive and we must think that everything will go well. We have two tough games ahead. We were not supposed to be here, but it happens to struggle sometimes.

"We must continue playing as we've always done. We didn't reach our targets by coincidence. We didn't want to play these games, but the lads are feeling well and that's important.

"I am optimistic because I have players who won the Euros starting from nothing when nobody believed in it. We must think about what we did to have more self-confidence, the team is solid and with quality.

"Our target is to win the World Cup, and in order to do it, we must win the next two games. We want to go to the World Cup to win it."

Mancini has handed maiden call-ups to Luiz Felipe and Joao Pedro, while Lorenzo Insigne and Nicolo Barella made the cut despite underperforming for their clubs.

Gianluigi Donnarumma, whose second-leg blunder proved costly in Paris Saint-Germain's Champions League last-16 loss against Real Madrid, is another familiar face among the Azzurri ranks, and Mancini is backing in the players he has selected.

"I am not worried, they [Insigne and Barella] have always done well with the national team," Mancini said when asked about the pair's form with Napoli and Inter respectively.

"Of course, there are highs and lows during a season. [Giorgio] Chiellini is feeling quite well and it's good that he played a little. 

"He probably won't play two games, but we'll talk and decide together. He knows his condition and he will tell me if he can play two games in five days.

Pressed whether Donnarumma's form was concerning, Mancini responded: "Absolutely not, it's better to have him with us than against."

Mancini also has Domenico Berardi and Gianluca Scamacca to call upon in his frontline, though he is slightly light on numbers at the back due to injuries, with right-back Giovanni Di Lorenzo having to be replaced in the squad by Mattia De Sciglio.

"Berardi and Scamacca are doing well, but I can't reveal the line-up today. We'll make our assessments starting from tomorrow. Except for defenders, the others are feeling quite well," Mancini said.

"I don't think there are big problems in midfield and attack."

Italy great Fabio Cannavaro insists the Azzurri cannot afford to fail to qualify for two consecutive World Cups.

The reigning European champions could not top their World Cup qualifying group, leaving them having to beat North Macedonia in the playoffs semi-final on Thursday to keep their hopes alive.

Italy would then have to bypass either Turkey or Cristiano Ronaldo's Portugal in the final to secure their spot at Qatar 2022, which means one of the previous two European Championship winners will not be present at the World Cup.

Robert Mancini's reinvigorated Azzurri responded to failure to qualify for FIFA's showpiece event in 2018 by lifting the delayed Euro 2020, and Cannavaro explained that it is vitally that they find a way through this year.

"Between us and qualifying for Qatar there could be Portugal, but also Turkey would not be a walk in the park," Cannavaro, who won the World Cup in 2006, told Italian newspaper Il Mattino.

"And even before that in Palermo, we must beat [North] Macedonia. We threw away a chance in Rome against Switzerland [in the group stages], there is no way we can not qualify for the World Cup for eight years.

"It would be a disaster for everyone. Mancini will find the resources to be able to qualify."

While Italy push for World Cup qualification, Russia will not be featuring in Qatar after FIFA excluded them due to the ongoing invasion of Ukraine, a decision Cannavaro supports.

When asked if FIFA had made the right call, he added: "Yes. Football is not a world apart. It had to give a signal and it did."

Dan Biggar could not hide his bitter disappointment following Wales’ shock 22-21 defeat by Italy in the Six Nations.

The skipper was earning his 100th cap, becoming only the seventh Welshman to achieve the feat, while Alun Wyn Jones became the first player to reach 150 Test appearances for a single nation, but their big days were marred in Cardiff.

Edoardo Padovani barged over late on to hand Italy a first victory in 37 attempts in the Six Nations.

Meanwhile, Wales suffered consecutive home defeats in the competition for the first time in 15 years, and Biggar pulled no punches when assessing his side's performance.

"It's probably the toughest interview I've had to do, simply not good enough," he said.

"We've said in the huddle now that's probably the last chance for a lot of players.

"We were chasing as high as we could get and from the get go, we weren't quite at it and you get punished.

"Too many boys not quite up to speed, we were second to loose balls and balls in the air.

"It's really disappointing that something that we pride ourselves on that requires no talent is work ethic."

By contrast, counterpart Michele Lamaro lauded his team-mates after their long-awaited win, their first Six Nations success since 2015.

"It's just unreal. I couldn't believe it," he smiled. "I want to stay with my family and team-mates and celebrate with them because we deserve it and we worked so hard to get here.

"It's the first step of our long process that we just started. I think just being in the moment until the end took us to the win."

Edoardo Padovani scored a last-gasp try as Wales' Six Nations campaign ended with a shock 22-21 defeat against Italy at the Principality Stadium.

Josh Adams had appeared to spare the blushes of the lacklustre when he crossed 11 minutes from time to put Wales ahead.

Kieran Crowley's Italy looked set for a 37th successive defeat in the competition at that stage, but there was to be one final twist in Cardiff.

Ange Capuozzo burst away from the tiring Welsh defence and offloaded to Padovani, who went in under the posts before Paolo Garbisi converted to complete a remarkable victory.

Italy head coach Roberto Mancini has left out Mario Balotelli from his squad for the upcoming World Cup playoffs, while handing maiden call-ups to Joao Pedro and Luiz Felipe.

The Azzurri failed to top their World Cup qualifying group, which leaves them having to beat North Macedonia in the playoff semi-finals on Thursday to set up a meeting against Turkey or Portugal five days later.

The draw means one of the two previous European Championship winners, Portugal and Italy, will not feature at the 2022 World Cup in Qatar.

Mancini has named a 33-man squad for the upcoming clash against North Macedonia in Palermo, with Balotelli snubbed for the introduction of Cagliari forward Joao Pedro, who was born in Brazil but has an Italian passport.

Lazio defender Luiz Felipe also qualifies under the same criteria and he features in the Italy squad for the first time, while Federico Chiesa and Leonardo Spinazzola miss out through injury.

Moise Kean, Alessio Romagnoli and Davide Calabria were also notable omissions, with Cristiano Biraghi expected to take Spinazzola's full-back spot and Roma's Nicolo Zaniolo filling in for Chiesa.

Matteo Politano, Stefano Sensi and Pierluigi Gollini - who replaces the injured Napoli goalkeeper Alex Meret - all return, with Manuel Locatelli called up despite testing positive for COVID-19 on Thursday.

Locatelli's Juventus colleague Leonardo Bonucci has made the squad even though he suffered a reoccurring problem with his calf in Wednesday's 3-0 Champions League aggregate loss to Villarreal.

Italy squad:

Alessio Cragno (Cagliari), Gianluigi Donnarumma (Paris Saint-Germain), Pierluigi Gollini (Tottenham), Salvatore Sirigu (Genoa); Francesco Acerbi (Lazio), Alessandro Bastoni (Inter), Cristiano Biraghi (Fiorentina), Leonardo Bonucci (Juventus), Giorgio Chiellini (Juventus), Giovanni Di Lorenzo (Napoli), Emerson Palmieri (Lyon), Alessandro Florenzi (Milan), Luiz Felipe (Lazio), Gianluca Mancini (Roma); Nicolo Barella (Inter), Bryan Cristante (Roma), Jorginho (Chelsea), Manuel Locatelli (Juventus), Lorenzo Pellegrini (Roma), Matteo Pessina (Atalanta), Stefano Sensi (Sampdoria), Sandro Tonali (Milan), Marco Verratti (Paris Saint-Germain); Andrea Belotti (Torino), Domenico Berardi (Sassuolo), Ciro Immobile (Lazio), Lorenzo Insigne (Napoli), Joao Pedro (Cagliari), Matteo Politano (Napoli), Giacomo Raspadori (Sassuolo), Gianluca Scamacca (Sassuolo) Mattia Zaccagni (Lazio), Nicolo Zaniolo (Roma).

Manchester City defender Ruben Dias has been left out of Portugal's squad for this month's crucial World Cup play-offs, as the 24-year-old continues his recovery from a hamstring injury.

The central defender has been out of action since sustaining the injury in the Premier League champions' FA Cup win over Peterborough United last month.

Fernando Santos will also be unable to call upon fellow injury absences Renato Sanches and Nelson Semedo, as he seeks to avoid being the first Portugal coach to fail to qualify for a major tournament since the country missed out on the 1998 World Cup in France.

After a last-gasp 2-1 loss to Serbia saw Portugal fail to qualify automatically for the World Cup, Portugal will host Turkey in a play-off semi-final on March 24, before the winner of that clash takes on either Italy or North Macedonia five days later for a place in Qatar.

Dias was named Premier League player of the season for the 2020-21 campaign, and has contributed to the league leaders keeping a joint-high 17 clean sheets in 29 top-flight games this term. 

In Dias' absence, uncapped Sporting CP defender Goncalo Inacio gets his second senior call-up, with 38-year-old Lille defender Jose Fonte and Porto's 39-year-old stalwart Pepe likely to form an experienced defensive partnership.

Cristiano Ronaldo, who has hit 115 goals in 184 appearances for his country's senior team, is one of three Manchester United players to make the squad, being joined by Diego Dalot and Bruno Fernandes.

Speaking to the press after announcing his squad, Santos emphasised the importance of the Turkey match, and insisted his 37-year-old captain remains a crucial part of his group.

"We have to win," said the Euro 2016 winner. "We have a goal, we have to fulfil it, it's a goal of the people. 

"All the national team's games will always be very important for the people. [We must] play for Portugal, as there have been others who have marked the history of Portuguese football.

"More important than anything is Portugal. That is the case for us and for the people that we are going to play for, and that also includes our captain Cristiano Ronaldo, who is a very important piece."

Although Dias will not play any part in the crucial match-up with Turkey, club team-mates Joao Cancelo and Bernardo Silva have both been named in Santos' squad.

Portugal squad: Anthony Lopes (Lyon), Diogo Costa (FC Porto), Rui Patricio (Roma); Cedric Soares (Arsenal), Joao Cancelo (Manchester City), Diogo Dalot (Manchester United), Goncalo Inacio (Sporting CP), Jose Fonte (Lille), Pepe (FC Porto), Nuno Mendes (Paris Saint-Germain), Raphael Guerreiro (Borussia Dortmund); Danilo Pereira (Paris Saint-Germain), Matheus Nunes (Sporting CP), William Carvalho (Real Betis), Ruben Neves (Wolves), Bruno Fernandes (Manchester United), Joao Moutinho (Wolves), Otavio Monteiro (FC Porto); Bernardo Silva (Manchester City), Joao Felix (Atletico Madrid), Diogo Jota (Liverpool), Goncalo Guedes (Valencia), Rafael Leao (Milan); Andre Silva (RB Leipzig), Cristiano Ronaldo (Manchester United).

All eyes will be on the Stade de France on Saturday as the 2022 Six Nations comes to a conclusion when leaders France take on England.

While the visitors can finish no higher than third place, Eddie Jones' men will revel in being the ultimate party poopers in Paris.

Victory for France in 'Le Crunch' will seal a first Grand Slam since 2010, though Les Blues could still finish top and land a first title since then should Ireland fail to beat Scotland.

Saturday's other fixture sees Wales take on pointless Italy in Cardiff and, while there may be little riding on that game, it will be a milestone occasion for a couple of players.

Ahead of the final round of fixtures, Stats Perform previews each match with help from Opta.

FRANCE V ENGLAND

FORM

The omens are good for France as two of their previous three Six Nations Grand Slams have been completed with victory over England in the final round, in 2004 and again six years later, while just one of the past nine games between these sides in the competition has been won by the visitors – England prevailing 31-21 in 2016.

Fabien Galthie's charges have lost just one of their past eight home games in the competition, with that solitary defeat coming at the hands of Scotland last year as they chased a big winning margin to pip Wales to the title.

England are aiming to avoid losing three matches in a single edition of the Six Nations for the third time in seven years playing under Eddie Jones, having also done so in 2018 and 2021, and for a fifth time overall. 

ONES TO WATCH

Damian Penaud, who has a joint-high three tries in this year's tournament, is back in France's starting XV after recovering from coronavirus, replacing the injured Yoram Moefana. France have scored seven tries from counter-attacks this year, which is at least three more than any other team, so pacey Penaud could cause some damage this weekend.

England will need to work incredibly hard if they are to stop arguably the world's top side right now and hope that their key players turn up. In Marcus Smith they boast a player who leads the way for points in 2022 with 63, 19 more than next-best Melvyn Jaminet.

IRELAND V SCOTLAND

FORM

Ireland must beat Scotland earlier on Saturday if they are to remain in title contention and they have a great recent record in this fixture, winning seven of their last eight Six Nations meetings.

That record is even better on home soil, meanwhile, having been victorious in 10 of the last 11 encounters in the competition, including each of the last five in a row. Scotland's only win in that run came at Croke Park in 2010.

Fourth-placed Scotland have won five of their last six away games in the tournament, however, which is as many as they had managed in their previous 43.

ONES TO WATCH

Ireland were made to work hard for their victory against an England side that played almost the entire 80 minutes with 14 men last week, but they did ultimately get the job done. Jamison Gibson-Park led the way for passes in that match with 59 – more than double any opposition player – and he has a joint-high three assists in this edition.

Finn Russell is level with Gibson-Park on three assists, but he has been surprisingly omitted from Scotland's squad for the match at the Aviva Stadium due to his growing indiscipline and poor form. Ali Price is next for Scotland on the assists list with two, and there will now be more focus on him on what is his 51st cap.

WALES V ITALY

FORM

Wales are aiming to climb two places and finish third and will be confident of fulfilling their half of the bargain by claiming a bonus-point win against bottom side Italy. The Dragons have won each of their last 14 in this fixture, last tasting defeat in 2007.

After losing at home to France in their most recent home match, Wales are aiming to avoid successive losses at the Principality Stadium in the competition for the first time in 15 years, when losing their final such game in 2006 and first in 2007.

Italy will claim the Wooden Spoon once again having lost all five games this year, stretching their record losing run in the tournament to 36 matches. The Azzurri's most recent win away from home came against Scotland in 2015.

ONES TO WATCH

This will be a special occasion for Dan Biggar, who is in line for his 100th cap, and Alun Wyn Jones, who returns for the first time since suffering a shoulder injury against New Zealand in October for his 150th appearance. That makes the Wales skipper the first player to win 150 or more caps for a single nation in history.

Ange Capuozzo has been handed a first Test start after making a big impression in an otherwise disappointing campaign for Italy. The Grenoble full-back has scored two tries in this year's Six Nations, accounting for half of Italy's total, with both of those coming in a 34-minute appearance against Scotland in round four.