England head coach Eddie Jones has named a new-look front row and recalled George Ford for the Six Nations game against Italy on Saturday.

The reigning champions went down 11-6 to Scotland on the opening weekend of the 2021 tournament, their first defeat to their Calcutta Cup rivals at Twickenham in 38 years. 

As he looks for a response following that setback, Jones has selected Ford at fly-half in his starting XV, meaning captain Owen Farrell switches to inside centre for the clash with the Azzurri. 

In the pack, the fit-again Mako Vunipola comes in to play opposite fellow prop Kyle Sinckler, while Luke Cowan-Dickie gets the nod at hooker ahead of Jamie George, who is on the bench. 

Courtney Lawes also gets a start at flanker, joining Tom Curry and Billy Vunipola in the back row.  

Ollie Lawrence – who was handed his first Six Nations start against Scotland – is absent from the 23-man squad entirely, with Henry Slade picked to play next to Farrell in midfield.  

"As always, we've picked what we think is our strongest 23 to try and win the game," Jones said.

"We're pleased to have Mako and Kyle back into the team and we've made some changes to our starting XV, but our finishers are just as important to our gameplan. We look at the whole 80 minutes.  

"We've trained very well this week, I've been very pleased with the players' attitudes and work-rate. We're hoping to put on a good performance on Saturday and kick on with our Six Nations campaign." 

England team to face Italy at Twickenham:

Elliot Daly, Anthony Watson, Henry Slade, Owen Farrell (captain), Jonny May, George Ford, Ben Youngs; Mako Vunipola, Luke Cowan-Dickie, Kyle Sinckler, Maro Itoje, Jonny Hill, Courtney Lawes, Tom Curry, Billy Vunipola

Replacements: Jamie George, Ellis Genge, Will Stuart, Charlie Ewels, Ben Earl, Jack Willi, Dan Robson, Max Malins.

Props Kyle Sinckler and Mako Vunipola have returned to the England squad for the Six Nations encounter with Italy at Twickenham on Saturday.

British and Irish Lions duo Sinckler and Vunipola missed the 11-6 Calcutta Cup defeat to Scotland on the opening day of the tournament due to suspension and an Achilles injury respectively.

They will be available to beef up the defending champions' pack against an Azzurri side smarting from a 50-10 hammering at the hands of a rampant France at Stadio Olimpico.

Harry Williams and Tom West will not feature for Eddie Jones' side after they were released to return to their clubs.

The Red Rose never got going in a poor performance versus dominant Scotland, but they won the tournament last year after losing their opening match to France and number eight Billy Vunipola said they can respond again.

He said: "It is frustrating. I won't lie. But this happened last year, and we managed to pull it back so it's massive for all of us to make sure we get around each other and whatever we need to fix this week we do as soon as possible.

"We only have a week to do it, which is probably the best thing for us. We don't have a fallow week to let that settle in and frustrate us.

"You never really forget these days, you never really forget these moments, and to be honest I don't really want to forget them.

"I want to move on from it, but I don't want to forget it as it keeps you sharp. Losing like this at Twickenham is never what you dream of."

England start their quest to retain the Six Nations title against Scotland on Saturday just over three months after they were crowned champions. 

The Red Rose dethroned Wales at the end of October, pipping France on points difference in a dramatic finale to a tournament that ended almost nine months after it started due to the COVID-19 pandemic. 

Eddie Jones' side are favourites to win the competition again, but Les Bleus are also well fancied to end an 11-year wait for Six Nations glory and face Italy in the first match. 

England do battle with Scotland for the Calcutta Cup at Twickenham, with Wales and Ireland locking horns in Cardiff on Sunday. 

Ahead of the opening round, we preview the upcoming matches with help from Opta.

ITALY v FRANCE

FORM

France have won 19 of their 21 previous Six Nations matches against Italy (L2), including their last seven in a row. Their two defeats in that time both came in Rome, in 2011 and 2013.  

Italy have lost their last 27 Six Nations matches, the longest losing streak in the history of the competition. Their last victory came at Murrayfield against Scotland in 2015, while they have not won at home since 2013. 

Les Bleus achieved a cumulative points difference of +31 in the first 20 minutes of their 2020 Six Nations matches. No other side managed a positive double-digit points difference in that period of matches, but Italy had a -39 difference. 

ONES TO WATCH

France wing Teddy Thomas scored a try in his last Test against Italy and is capable of lighting up the tournament. He can get off to a storming start in Rome.

Paolo Garbisi caught the eye at fly-half last year after being handed his debut against Ireland in October. Hopefully for his country, there is still much more to come from the 20-year-old.

ENGLAND v SCOTLAND

FORM

The last time England hosted Scotland in the Six Nations they drew 38-38 two years ago. Scotland clawed back the biggest ever half-time deficit (-24 pts, 7-31) by a side to avoid defeat in the tournament’s history, almost snatching victory before a late George Ford try denied them. 

Scotland have never beaten England at Twickenham in the Six Nations (D1, L9), their last victory against them the Red Rose at the London venue came in 1983 in the Five Nations (22-12).  

Gregor Townsend's side concluded the 2020 edition by winning their last three games in a row, their best run in the Championship since Italy joined in 2000. 

ONES TO WATCH

England captain Owen Farrell has scored exactly 1,000 Test points, one of just six men to reach that milestone. He is just four points away from reaching a century against Scotland.

Finn Russell returns to the Scotland side and the creativity provided by the fly-half will be key for Townsend's men.

WALES v IRELAND

FORM

Wales have lost their last two home games in the Six Nations, the last time they suffered three consecutive defeats at home was in 2002-03. Wayne Pivac's side have lost their last four games in the competition, their worst streak since 2006-07 (L5).  

No team scored more tries than Ireland in the Six Nations last year (17, along with France), four of those were launched from the back of a scrum. Wales (2) were the only other side to score multiple tries following a scrum.  

Ireland scored seven tries in the final quarter of their fixtures in 2020, more than any other side. Wales, meanwhile, scored the joint-second most in that period (6, level with England). 

ONES TO WATCH

Louis Rees-Zammit turned 20 this week and the Wales wing can celebrate in style with a livewire display at the Principality Stadium.

Ireland centre Garry Ringrose had terrible luck with injuries last year, but he is ready to fire on all cylinders in 2021.

French Rugby Federation (FFR) president Bernard Laporte says there is "no question" that the Six Nations will be staged this year.

The Telegraph this weekend reported that the tournament was in doubt after the French sports ministry imposed a ban on playing cross-border elite sports with clubs from the United Kingdom due to a new strain of coronavirus.

With the European Champions Cup and Challenge Cup reportedly set to be suspended, the French government and Six Nations officials are expected to hold talks on Monday.

Yet Laporte does not believe there is any doubt that the competition, which starts in just four weeks' time, can be staged. 

He told RMC on Sunday: "It's a puzzle, but I think we should not be alarmed for the Six Nations tournament.

"The tournament will be played, with a health protocol dictated by the government, and linked to this mutant virus. Everything went well in the autumn [when the Autumn Nations Cup was staged], so will the upcoming Six Nations tournament, I'm no more worried than that."

The former Les Bleus coach added: "We have a meeting at the beginning of the week with the ministry of sports, a meeting also with the Six Nations Council.

"But we already talked to each other every day, and today there is no question of considering anything, except that we will play the tournament."

France are due to face Italy in the first game of the Six Nations at Stadio Olimpico on February 6.