The red-hot Green Bay Packers ended the Arizona Cardinals' perfect start to the season while extending their winning streak to seven games following a 24-21 victory in the NFL on Thursday.

Kyler Murray's Cardinals had won seven consecutive games to open the season, but Arizona finally came unstuck against Aaron Rodgers and the high-flying Packers.

Rodgers (22-of-37 passing for 184 yards without an interception) threw two touchdown passes to Randall Cobb as the Packers held on to beat the Cardinals – playing for the first time without star defensive end JJ Watt – after Murray's stunning last-gasp interception.

Chase Edmonds' 11-yard run gave the Cardinals a first-quarter lead – the Arizona star had entered Week 8 with 397 rushing yards this season, the most by any player in the NFL without a rushing TD.

Rodgers and the Packers took control from that point as Jones' second-quarter TD run and Green Bay's superstar quarterback Rodgers' pass to Cobb in the third quarter put the visitors ahead 17-7.

James Conner did strike before the end of the third to close the gap to three points, though the Rodgers-Cobb combination struck again early in the fourth to make it 24-14 in the Packers' favour.

Conner's second rushing touchdown set up a thrilling finish but as the Cardinals attempted to rally to their eighth straight victory, Murray (22-of-33 passing for 274 yards, no TDs and two interceptions) threw an interception on second-and-goal with 12 seconds remaining – Rasul Douglas on hand to snatch the ball in the corner of the end zone.