The Miami Dolphins rattled up the highest points total in the NFL since 1966 as they overwhelmed the winless Denver Broncos 70-20.
Rookie De’Von Achane ran for 203 yards, two touchdowns and collected a touchdown pass from Tua Tagovailoa – who completed his first 17 passes – while fellow running back Raheen Mostert ran for three touchdowns and caught another.
Coach Mike McDaniel opted against a last-ditch field-goal attempt which would have broken the record of 72 points set by Washington against the Giants 57 years ago.
AFC East rivals Buffalo Bills also had a commanding victory as they routed the Washington Commanders 37-3.
Josh Allen threw for one touchdown and ran for another as the Bills defence sacked home quarterback Sam Howell nine times.
Howell threw four interceptions, once of which was returned for a touchdown by AJ Epenesa – as the Commanders went scoreless until a field goal with 46 seconds left on the clock.
Elsewhere in the AFC East, the New England Patriots won 15-10 to beat the New York Jets for a 15th successive game and avoid a first 0-3 start since 2000.
Patrick Mahomes threw three touchdown passes, two to Jerick McKinnon, but had to take second billing to a watching Taylor Swift as Kansas City Chiefs ease passed the winless Chicago Bears 41-10.
Swift cheered on from a suite at the invitation of Chiefs tight end Travis Kelce, with whom she has been romantically linked and who also grabbed a touchdown pass from Mahomes.
Reigning MVP Mahomes threw for 272 yards, Isiah Pacheco and Clyde Edwards-Helaire adding touchdown runs as the Bears fell to a 13th straight defeat ahead of a clash with the Broncos next week.
Kenny Pickett passed for 235 yards with two touchdowns as the Pittsburgh Steelers held off a fourth quarter comeback from the Las Vegas Raiders to win 23-18.
The Raiders, who trailed 23-7 going into the final quarter, cut the deficit to eight points but opted to take a field goal on fourth and four in the closing moments.
Dallas Cowboys’ impressive start to the season hit came to an abrupt end as they lost 28-16 at Arizona Cardinals, Joshua Dobbs throwing for a touchdown and 189 yards to secure his first win as a starting quarterback in his seventh NFL season.
Quarterback Derek Carr was forced off with a shoulder injury as the New Orleans Saints coughed up a 17-0 lead to lose 18-7 to the Green Bay Packers while Kenneth Walker II rushed for a pair of touchdowns as the Seattle Seahawks won 37-27 over the winless Carolina Panthers.
The Minnesota Vikings are also 0-3 after they went down 28-24 to the Los Angeles Chargers, Justin Herbert completing 40 of 47 passes – a franchise record 18 of them to Keenan Allen – for 405 yards and three touchdowns.
Andrew Beck returned a kick-off 85 yards for a touchdown and CJ Stroud threw for two more as the Houston Texans beat the faltering Jacksonville Jaguars 37-17.
Matt Gay kicked four field goals from more than 50 yards, including the game winner in overtime from 53 yards, as the Indianapolis Colts won 22-19 to inflict a first defeat of the season on the Baltimore Ravens.
The Tennessee Titans totalled just 94 yards in offence as they went down 27-3 at the Cleveland Browns, while the Atlanta Falcons went down 20-6 at the Detroit Lions.
Dolphins' Tagovailoa throws 3 interceptions before leaving with concussion in Bills' rout
Tua Tagovailoa threw three interceptions before leaving with a concussion and James Cook had three touchdowns as the Buffalo Bills rolled to a 31-10 rout of the Miami Dolphins on Thursday night.
Tagovailoa, who has a history of dealing with head injuries, collided with Bills defensive back Demar Hamlin in the third quarter on a fourth-down keeper and hit the back of his head against the turf.
He remained down for about two minutes before getting to his feet and walking to the sideline. Tagovailoa made his way to the tunnel not long afterward, looking into the stands, appeared to smile and departed for the Dolphins' locker room.
The Dolphins needed almost no time before announcing it was a concussion.
Tagovailoa positioned himself for a big pay bump with an injury-free and productive 2023. He threw for 29 touchdowns and a league-best 4,624 yards.
Cook caught a 17-yard touchdown pass from Josh Allen and scored on runs of 1 and 49 yards in the first half, flipping into the end zone when he gave the Bills a 24-7 lead.
Allen, playing with a glove on his left non-throwing hand after hurting it in Buffalo's opener, completed 13 of 19 passes for 139 yards. He's 12-2 against the Dolphins and the Bills are 14-2 against Miami since coach Sean McDermott’s first year as head coach in 2017.
Miami’s star receiver Tyreek Hill was held to three catches for 24 yards during a week in which he dominated national headlines. Hill was pulled from his sports car by Miami-Dade County police officers, pushed face-first onto a street and handcuffed during a traffic stop outside the Dolphins’ home stadium hours before their season opener.
Bengals QB Burrow insists injured wrist no longer affecting throws
Joe Burrow insists the wrist injury that ended his 2023 season is not preventing him from making downfield throws after struggling in the Cincinnati Bengals' Week 1 loss.
The Bengals' 2024 campaign got off to a miserable start as they were beaten 16-10 by the New England Patriots, who had the joint-second worst record in the league last year at 4-13.
Burrow threw for 164 yards with no touchdowns or interceptions, being sacked three times. He did complete 21 of his 29 attempted passes, but only six of those completed passes travelled more than 10 yards in the air.
Burrow – who was recently surpassed as the NFL's highest-paid player by Dallas Cowboys quarterback Dak Prescott – was repeatedly seen flexing his wrist during the game.
He suffered a wrist ligament injury versus the Baltimore Ravens in Week 11 last season, leading him to undergo reconstructive surgery.
However, he is adamant he is no longer feeling the effects of that issue, saying: "It feels better this week than it did last week, than it did the week before, so it's continually getting better.
"That's part of ligament injuries. If you don't move it, you're going to lose it.
"I'm always moving it around, keeping it loose, keeping my mobility the way it's supposed to be, so it's going to continue to happen."
Having sat out the final seven games of 2023 as the Bengals missed the playoffs for the first time since 2020, Burrow is simply grateful to be back out on the field.
"It's a luxury right now to be criticised by you guys about how we played on Sunday, because I was sitting in the wings for seven weeks last year," he said. "I'm just excited to be out there."
The Bengals face the Kansas City Chiefs in a rematch of the AFC Championship games from the 2021 and 2022 seasons on Sunday, before taking on the Washington Commanders in Week 3.
'I know I'm going to be a Cowboy' - Parsons confident over Dallas stay
Micah Parsons is confident he will remain with the Dallas Cowboys but is currently more focused on winning than signing a lucrative extension.
The Cowboys have already signed Dak Prescott and CeeDee Lamb to new deals, with Parsons next in line to be given a new contract.
He is in the final year of his four-year rookie contract, with Dallas already exercising their $21million fifth-year option on his deal.
The former Defensive Rookie of the Year could land a deal that makes him the NFL's richest defensive player.
However, Parsons is in no hurry to put pen to paper as he knows his future lies in Texas.
"I know I'm going to be a Cowboy," he said on Monday on his 'The Edge with Micah Parsons' podcast. "There's nothing like Cowboy Nation. I think the love is very mutual.
"As for me, I'm just focused on winning games. I want to win those big games. I want to win those playoff games, get to the Super Bowl. For me, the contract is not really what I'm worried about."
Prescott and the Cowboys agreed to a four-year deal worth $240m hours before they opened the season with a win over the Cleveland Browns on Sunday, while Lamb signed his four-year, $136m contract two weeks earlier, making him the second-highest-paid non-quarterback in NFL history.
Parsons was happy to see his team-mates commit their future to the club, in particular heaping praise on Prescott's influence.
"We're happy it gets done because now, it puts a lot of talk to the side," Parsons added. "We're like, 'Man, we got our quarterback now.'
"We can really just focus, like Dak said, on winning games. ... So, having our guys, CeeDee Lamb and Dak done, it means the world to us.
"Dak is that guy, no BS. He deserves everything that he [gets]. He never cheated the game, he comes in every day with a positive attitude, great work ethic, and he's always first one in, last one out. Consistently being the best person/player you could possibly be.
"He never cheats the game, and that's the most important part. So, when a guy like that gets his money, you say he earned every single dollar. I could not be more happy for him."
The Cowboys will play their first NFL home game of the season against the New Orleans Saints on Sunday.
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