The Miami Dolphins rattled up the highest points total in the NFL since 1966 as they overwhelmed the winless Denver Broncos 70-20.
Rookie De’Von Achane ran for 203 yards, two touchdowns and collected a touchdown pass from Tua Tagovailoa – who completed his first 17 passes – while fellow running back Raheen Mostert ran for three touchdowns and caught another.
Coach Mike McDaniel opted against a last-ditch field-goal attempt which would have broken the record of 72 points set by Washington against the Giants 57 years ago.
AFC East rivals Buffalo Bills also had a commanding victory as they routed the Washington Commanders 37-3.
Josh Allen threw for one touchdown and ran for another as the Bills defence sacked home quarterback Sam Howell nine times.
Howell threw four interceptions, once of which was returned for a touchdown by AJ Epenesa – as the Commanders went scoreless until a field goal with 46 seconds left on the clock.
Elsewhere in the AFC East, the New England Patriots won 15-10 to beat the New York Jets for a 15th successive game and avoid a first 0-3 start since 2000.
Patrick Mahomes threw three touchdown passes, two to Jerick McKinnon, but had to take second billing to a watching Taylor Swift as Kansas City Chiefs ease passed the winless Chicago Bears 41-10.
Swift cheered on from a suite at the invitation of Chiefs tight end Travis Kelce, with whom she has been romantically linked and who also grabbed a touchdown pass from Mahomes.
Reigning MVP Mahomes threw for 272 yards, Isiah Pacheco and Clyde Edwards-Helaire adding touchdown runs as the Bears fell to a 13th straight defeat ahead of a clash with the Broncos next week.
Kenny Pickett passed for 235 yards with two touchdowns as the Pittsburgh Steelers held off a fourth quarter comeback from the Las Vegas Raiders to win 23-18.
The Raiders, who trailed 23-7 going into the final quarter, cut the deficit to eight points but opted to take a field goal on fourth and four in the closing moments.
Dallas Cowboys’ impressive start to the season hit came to an abrupt end as they lost 28-16 at Arizona Cardinals, Joshua Dobbs throwing for a touchdown and 189 yards to secure his first win as a starting quarterback in his seventh NFL season.
Quarterback Derek Carr was forced off with a shoulder injury as the New Orleans Saints coughed up a 17-0 lead to lose 18-7 to the Green Bay Packers while Kenneth Walker II rushed for a pair of touchdowns as the Seattle Seahawks won 37-27 over the winless Carolina Panthers.
The Minnesota Vikings are also 0-3 after they went down 28-24 to the Los Angeles Chargers, Justin Herbert completing 40 of 47 passes – a franchise record 18 of them to Keenan Allen – for 405 yards and three touchdowns.
Andrew Beck returned a kick-off 85 yards for a touchdown and CJ Stroud threw for two more as the Houston Texans beat the faltering Jacksonville Jaguars 37-17.
Matt Gay kicked four field goals from more than 50 yards, including the game winner in overtime from 53 yards, as the Indianapolis Colts won 22-19 to inflict a first defeat of the season on the Baltimore Ravens.
The Tennessee Titans totalled just 94 yards in offence as they went down 27-3 at the Cleveland Browns, while the Atlanta Falcons went down 20-6 at the Detroit Lions.
Cowboys quarterback Prescott reportedly expected to miss multiple weeks with hamstring injury
The path to the play-offs is now even tougher for the Dallas Cowboys.
Quarterback Dak Prescott will reportedly miss several weeks with a hamstring injury sustained in Sunday's 27-21 loss to the Atlanta Falcons.
The severity of the injury was determined following an MRI, and reported Monday from multiple media outlets.
Prescott is planning to get a second opinion, and the Cowboys have not decided if they will place him on injured reserve, which would keep him on the sideline a minimum of four games.
Prescott, who signed a record-breaking, $240million contract hours before this season's opener, suffered the injury late in the third quarter.
He was replaced by Cooper Rush, and the seven-year backup will get the start this Sunday against the Philadelphia Eagles.
Rush completed 13-of-25 passes for 115 yards and a touchdown against the Falcons, but couldn't rally Dallas all the way back.
The Cowboys ended up losing their third straight game to drop to 3-5, which matches the total number of losses the team had each of the last three seasons.
They now sit in third place in the NFC East, 3 1/2 games behind the division-leading Washington Commanders.
Rush has found some success as a fill-in starter for the Cowboys, though, the 30-year-old hasn't been forced into the starting role since 2022.
In six career starts for Dallas, he's gone 5-1 with 1,281 passing yards with seven touchdowns, four interceptions and an 83.6 rating.
There is some good news for the Cowboys, though, as star defensive end Micah Parsons is likely to return this Sunday after missing the last four games with a high-ankle sprain.
Cowboys quarterback Prescott expected to miss multiple weeks with hamstring injury
The path to the play-offs is now even tougher for the Dallas Cowboys.
Quarterback Dak Prescott will reportedly miss several weeks with a hamstring injury sustained in Sunday's 27-21 loss to the Atlanta Falcons.
The severity of the injury was determined Monday following an MRI.
Prescott is planning to get a second opinion, and the Cowboys have not decided if they will place him on injured reserve, which would keep him on the sideline a minimum of four games.
Prescott, who signed a record-breaking, $240million contract hours before this season's opener, suffered the injury late in the third quarter.
He was replaced by Cooper Rush, and the seven-year backup will get the start this Sunday against the Philadelphia Eagles.
Rush completed 13-of-25 passes for 115 yards and a touchdown against the Falcons, but couldn't rally Dallas all the way back.
The Cowboys ended up losing their third straight game to drop to 3-5, which matches the total number of losses the team had each of the last three seasons.
They now sit in third place in the NFC East, 3 1/2 games behind the division-leading Washington Commanders.
Rush has found some success as a fill-in starter for the Cowboys, though, the 30-year-old hasn't been forced into the starting role since 2022.
In six career starts for Dallas, he's gone 5-1 with 1,281 passing yards with seven touchdowns, four interceptions and an 83.6 rating.
There is some good news for the Cowboys, though, as star defensive end Micah Parsons is likely to return this Sunday after missing the last four games with a high-ankle sprain.
Stumbling Saints fire head coach Allen
The New Orleans Saints fired head coach Dennis Allen on Monday, one day after the team’s losing streak reached seven games with a 23-22 defeat to the lowly Carolina Panthers.
New Orleans got off to an unexpected strong start to the 2024 season by outscoring its first two opponents 91-29 in a pair of victories.
The Saints lost their next two games by just a combined five points, but then it really started to unravel for the team.
New Orleans’ next four defeats all came by 13 points or more, and on Sunday, the Panthers pulled out a 23-22 win over the Saints after Carolina entered the meeting with a 1-7 record.
Allen was promoted from New Orleans' defensive coordinator to head coach after the 2021 season, and the Saints posted an 18-25 record under him with no play-off appearances.
The Saints (2-7) are expected to name special teams coordinator Darren Rizzi as interim head coach ahead of their Week 10 visit from the NFC South-leading Atlanta Falcons (6-3).
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