Andy Murray was beaten by fellow veteran Fabio Fognini to suffer a disappointing first-round exit at the Italian Open.
Murray, fresh from claiming success at an ATP Challenger event in Aix-en-Provence on Sunday, had hoped to extend his five-match winning streak but instead saw his time in Rome end early to the 35-year-old home favourite.
A 6-4 4-6 6-4 defeat to the world number 130 halts the momentum of the Briton, who will now turn his attention to the French Open later this month.
Three-time grand slam winner Murray made the worst possible start in Italy with Fognini able to break him in his opening service game.
While the Scot did force a number of opportunities to break back at 3-2, he failed to seize the moment and his frustration boiled over later in the set with a debate occurring with umpire Mohamed Lahyani over a tight line call that saw Fognini go 5-3 up.
Fognini went on to clinch a 69-minute opener but quickly found himself 4-0 down in the second with Murray hitting his straps, albeit helped by a string of double-faults from his opponent.
A second-set wobble saw the veterans exchange breaks before Murray did force a decider with the encounter by that point edging past the two-hour mark.
Despite Fognini seemingly struggling physically during the second set, he found a new lease of life and took the initiative with an early break in the third.
Murray tried to keep pace with the Italian, who was mixing an array of baseline winners with unforced errors but a concern for the two-time Wimbledon winner occurred when he held his back during the seventh game of the third.
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It was not enough to stop the new world number 42 from continuing, and yet there would be no big fightback on this occasion with Fognini earning a fifth victory in nine meetings thanks to an ace after two hours and 55 minutes.
This latest first-round exit at an ATP 1000 event on clay, after similar losses in Madrid and Monto-Carlo, will give Murray around 10 days preparation before Roland Garros begins on May 22 where he is now unlikely to be seeded.
Elsewhere, fellow Briton Kyle Edmund was also knocked out in the Italian Open first round after he suffered a 6-1 6-3 defeat to Alexandre Muller.
World number 473 Edmund saw his struggles continue against a French player who broke into the top 100 last month.
Muller managed to wrap up the first set in 23 minutes in Rome and, while Edmund was able to push his opponent more in the second, the former Australian Open semi-finalist was consigned to a third consecutive loss.
Sinner inspires comeback to help Italy reach Davis Cup semi-finals
Jannik Sinner kept Italy's hopes of retaining the Davis Cup alive after winning matches in the singles and doubles to inspire a 2-1 comeback triumph over Argentina on Thursday.
Sinner and Matteo Berrettini edged Maximo Gonzalez and Andres Molteni 6-4 7-5 in the deciding game to set up a rematch of last year's showpiece against Australia in the final four.
However, the Italians started off on the back foot when Francisco Cerundolo downed Olympic bronze medallist Lorenzo Musetti 6-4 6-1 in an hour and 29 minutes.
Musetti converted just two of the eight break points he was presented with, as Cerundolo put Argentina on the brink of reaching the semi-finals for the first time since 2016.
But two-time grand slam champion Sinner, who won the ATP Finals last weekend, carried his momentum forward from Turin against Sebastian Baez.
The world number one breezed to a 6-2 6-1 win over his opponent, serving seven aces to the Argentine's one, while also saving all four break points he faced.
Sinner then returned to the court alongside Berrettini, with the pair replacing Simone Bolelli and Andrea Vavassori in the must-win clash.
The pair won 90% of their first-serve points and fended off all five break points they faced, earning a key break at 5-5 in the second set before surging to victory.
"It was a must-win match," said Sinner. "Very different conditions. The court is very, very fast and tough to play.
"I haven't had so much time to adapt to the conditions, but I'm happy about today."
Data Debrief: The Italian Job
Italy edged closer to becoming only the sixth nation to retain the Davis Cup since the final stage was introduced 52 years ago, and first since the Czech Republic in 2013.
But they were inspired by Sinner once again, who proved why he will end the year at the summit of the ATP rankings.
And after leading Italy to their first Davis Cup title since 1976 with a victory against Australia's Alex de Minaur last year, he will fancy his chances this time around.
Ebden and Thompson send Australia to third straight Davis Cup semi
Matthew Ebden and Jordan Thompson booked Australia's place in the Davis Cup semi-finals after the pair clinched their deciding match against the United States to win 2-1.
The pair, who won gold at the Paris Olympics, beat Tommy Paul and Ben Shelton 6-4 6-4 to put Lleyton Hewitt's side into their third successive semi-final at the men's team event.
Australia, who have won the tournament 28 times, largely had Thanasi Kokkinakis to thank after his remarkable triumph over Shelton in the first match of the day.
Kokkinakis saved four match points and let slip six of his own before eventually prevailing 6-1 4-6 7-6 (16-14) in an engrossing encounter that lasted two hours and 14 minutes.
However, in the rematch of a recent ATP Finals group-stage match, Taylor Fritz emerged victorious over Alex De Minaur as he did in Turin a week ago.
Despite De Minaur going 2-0 up in the second set, Fritz roared back to earn a 6-3 6-4 victory to send the tie the distance in Malaga.
But Australia held their nerve, and will discover their opponents later on Thursday when reigning champions Italy take on Argentina.
Ebden and Thompson’s win came after United States’ captain Bob Bryan opted for a late change, with Paul and Shelton replacing Austin Krajicek and Rajeev Ram.
“We were expecting the other pair, but we knew they’ve got incredible players who can play doubles,” said Ebden.
“We were ready. A slight adjustment obviously. More huge serving singles players than the doubles craft, maybe, but it was just as big a challenge as any.
"Out here, finals live match, just to play with Jordan here was real fun. Following what Kokk did, unfortunately Alex went down, but what a day. So fun, so happy.”
Data Debrief: Australia ready to right Davis Cup wrongs
Australia have failed to win the Davis Cup since 2003, but they will be confident of halting that streak this time around.
If they take the trophy, they will have reason to thank Kokkinakis, whose tie-break win against Shelton was the longest an Australian player had featured in at the tournament, surpassing Pat Rafter's win over David Rikl in the 1997 quarter-finals of the competition (15-13).
Ebden and Thompson also shone when it mattered most, serving four aces compared to Paul and Shelton's two, while also winning 92% of their first-serve points.
Paolini and Bronzetti seal fifth Billie Jean King Cup for Italy
Victories for Jasmine Paolini and Lucia Bronzetti handed Italy their fifth Billie Jean King Cup title as they overcame Slovakia in Wednesday's final in Malaga.
Italy, who were beaten in last year's final by Canada, overcame Poland in the semi-finals on Monday as Paolini partnered Sara Errani for a decisive doubles win over world number two Iga Swiatek and Katarzyna Kawa.
The showpiece contest began with Bronzetti triumphing 6-2 6-4 against Viktoria Hruncakova, before Paolini took to the court to face Rebecca Sramkova.
The world number four – who won doubles gold at the Paris Olympics in August to cap her breakout year – eased past Sramkova by a 6-2 6-1 scoreline to ensure a doubles match was not required.
Speaking after Italy claimed the trophy for the first time since 2011, Bronzetti heaped praise upon her team-mate and revealed she had struggled to sleep before playing in front of 12-time grand slam champion King.
"Jasmine raised her level really high this year. She's an example for all of us," Bronzetti said.
Asked about King's presence in the crowd, Bronzetti added: "She is a great person, a great legend. I didn't sleep very well.
"You're not playing just for yourself. You're playing for your team and your country. We all want this trophy, and it is our dream, all Italians."
Data Debrief: Five-star Italy
Italy have claimed their fifth Billie Jean King Cup, having previously triumphed in 2006, 2009, 2010 and 2013.
Only the United States (18), Czechoslovakia/Czechia (11) and Australia (seven) have won more. Spain and Russia (also including the USSR and Russian Tennis Federation) have also tasted success five times.
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