Juventus wide player Juan Cuadrado has tested positive for coronavirus and will miss the clash with Serie A leaders Milan on Wednesday.

The Colombia international is asymptomatic but has begun a period of self-isolation, the Italian champions confirmed.

The news comes just a day after left-back Alex Sandro was ruled out after returning a positive test for the virus.

It means head coach Andrea Pirlo will be without two of his first-choice full-backs for the game at San Siro against Stefano Pioli's side, who are the only unbeaten team in Europe's top five leagues in the 2020-21 season.

The club said in a statement: "Juventus Football Club announces that, during the checks provided for by the protocol in force, Juan Cuadrado has emerged positive with COVID-19. The player has already been placed in solitary confinement and is asymptomatic."

Cuadrado, 32, has made 13 appearances in Serie A this term, scoring once.

Juve head into the Milan contest with a 10-point deficit to the league leaders, albeit with a game in hand.

While they have lost only once in 14 matches, Juve have won just seven times, leaving them in fifth place with 27 points.

They are hoping to avoid losing back-to-back league games against the Rossoneri for the first time since 2010, having been beaten 4-2 in the previous meeting last July.

The last time they faced Milan when behind them in the table was in November 2015, when a Paulo Dybala goal secured a 1-0 victory.

The past 12 months saw another Juventus title in Serie A, but 2020 comes to a close with Milan back in the trophy hunt at the top of the table.

Although the Rossoneri have not won the Scudetto since 2011, they lead the way through 14 matches heading into the new year.

Rivals Inter are a point further back, while Juve are back in sixth after losing their unbeaten record last time out against Fiorentina.

To mark the end of an intriguing year, Opta calculated a 'Top XI' for Serie A in 2020, including a host of big names - but notably missing one superstar.

GOALKEEPER: MARCO SILVESTRI

Hellas Verona have conceded just 14 goals so far this season and, across the year as a whole, Silvestri saved 74 per cent of the shots he faced, trailing only Juan Musso among keepers with at least 10 appearances.

DEFENDER: JUAN CUADRADO

Juventus' converted winger Cuadrado continues to display his attacking qualities from right-back. Among all defenders in 2020, he played the most passes into the opposition half (1,044) and trailed only Cristiano Biraghi (eight) for assists with a haul of seven.

DEFENDER: MATTHIJS DE LIGT

Lining up next to his Bianconeri team-mate, De Ligt has played a huge role in Juve's continued success. They won 65 per cent of their Serie A matches and conceded 1.0 goals per game with the Dutchman in the side in 2020, coming out on top just 36 per cent of the time while conceding 1.4 goals on average when he was missing.

DEFENDER: FRANCESCO ACERBI

Lazio's form has fallen away a little this season, but Acerbi is certainly not to blame. He recovered the ball 177 times in the league in 2020; Rafael Toloi (179) was the only centre-back to do so on more occasions.

DEFENDER: THEO HERNANDEZ

The first Milan entry unsurprisingly belongs to left-back Hernandez. He was directly involved in 11 goals (six goals, five assists) in 2020 and also completed the most successful dribbles in the competition (57).

MIDFIELDER: RODRIGO DE PAUL

De Paul has been linked with a host of clubs, including Inter, where another player in this list would surely thrive on his service. The Udinese midfielder played more accurate crosses (36) than anyone else in Serie A this year.

MIDFIELDER: FRANCK KESSIE

A key part of Milan's climb up the table, Kessie has been a dominant force in the middle of midfield. He recovered the ball 246 times in 2020, the most of any outfield player in the league.

MIDFIELDER: HAKAN CALHANOGLU

Once Kessie wins the ball, it is over to Calhanoglu to get Milan on the attack. He created 99 chances and provided 14 assists in 2020, both league highs.

FORWARD: ALEJANDRO GOMEZ

Talisman Papu Gomez looks set to leave Atalanta in January but starred again in what may prove to be his final full year in Bergamo. Complementing his creative talents, he led the press by winning possession 28 times in the final third of the pitch - ranking third in this regard.

FORWARD: ROMELU LUKAKU

Zlatan Ibrahimovic has been outstanding back at Milan, but he does not make the cut. Nor does Ciro Immobile. It is Inter striker Lukaku who leads the line after scoring 22 times in 2020, the most of any player to attempt fewer than 100 shots. Sixteen were from open play, behind only Cristiano Ronaldo and Immobile (both 17).

FORWARD: CRISTIANO RONALDO

Who else? Aged 35, Ronaldo scored 33 times in the league for Juve in 2020. Only Felice Borel (41 in 1933) and Gunnar Nordahl (36 in 1950) have ever topped that mark in Serie A.

Not content just to lead the Italian top flight, Ronaldo has the edge over Robert Lewandowski (32) across Europe's 'top five' leagues heading into the final matches of 2020. He scored the most goals across the continent in five calendar years between 2011 and 2019.

Andrea Pirlo refused to blame Juan Cuadrado's dismissal for Juventus' heavy home loss to Fiorentina and instead questioned the attitude of his players heading into the match.

Juve suffered their first Serie A defeat under Pirlo in his 13th league match in charge, going down 3-0 in what was also their heaviest loss since moving to the Allianz Stadium in 2011.

Cuadrado caught Gaetano Castrovilli on the shin and was issued a red card on his 200th appearance for the Turin giants – upgraded from a yellow following a VAR check – with only 18 minutes on the clock.

Dusan Vlahovic had given Fiorentina an early lead by that point and Juve could not respond, conceding again through Alex Sandro's own goal and Martin Caceres' tap-in.

Juve had a couple of penalty appeals turned down in Tuesday's match, their last of 2020, but Pirlo conceded his team simply failed to turn up.

"What happened with the red card cannot be used as an alibi," he told Sky Sport Italia. "The result was not down to Fiorentina's attitude but the lack of ours.

"When this is the case you face bad situations like this. In games before Christmas it can happen then you have your mind on the holidays. We were unfocused and could not recover.

"The images for the sending off seem clear to me. There could have been some decisions in our favour, but that's not something I want to comment on – you can see for yourself.

Juve had more possession than Fiorentina (54 per cent) and more shots (13 to 10) yet ultimately saw a 13-game unbeaten run come to a shuddering halt. 

Leonardo Bonucci in particular struggled – the experienced defender arguably at fault for all three of the opposition goals.

He lost possession six times in all and won only half of his 10 duels, but Pirlo stood by his skipper at full-time.

"Bad evenings like these happen to everyone," he said. "Up until this point he has made some great performances.

"It happens to everyone. He is our captain and we still have great faith in him."

Juve suffered a double title blow of sorts on Tuesday, this defeat to Fiorentina coming hours after Napoli won their appeal against October's abandoned fixture between the sides.

The Bianconeri had been awarded a 3-0 forfeit win after Napoli failed to turn up due to a travel ban put in place by local authorities after Piotr Zielinski, Eljif Elmas and a member of staff had tested positive for COVID-19.

But the Italian National Olympic Committee's Collegio di Garanzia dello Sport – the highest sports authority in the country – ruled in the Napoli's favour, meaning the game must be replayed in early 2021.

Juve are therefore three points worse off, now seven adrift of leaders Milan, and Pirlo questioned the fairness of the decision.

"We don't mind playing the game again. I'm more disappointed for the other teams that have travelled and played without far more players who had COVID," he said. "They showed great fairness by playing anyway.

"I won't say if the ruling was correct or not, but it didn't seem fair to the other teams who carried on and played in more difficult situations."

Ten-man Juventus' unbeaten start to the Serie A season was ended by Fiorentina as they suffered a humbling 3-0 loss at the Allianz Stadium.

The champions had gone 12 games without a loss in the top flight under Andrea Pirlo prior to Tuesday's setback, coming on the day they discovered their 3-0 forfeit win over Napoli in October has been revoked following their opponents' successful appeal.

Dusan Vlahovic scored early on for Fiorentina and Juve then lost Juan Cuadrado with 18 minutes played, the referee upgrading the yellow card he initially showed to a red following a VAR check.

Juve were unable to hit back and conceded twice more in the final 14 minutes, with Alex Sandro putting into his net and their former player Martin Caceres tapping in to inflict a further Scudetto blow on Pirlo's men.
 

Manchester United, Inter and Ajax were the big Champions League casualties as the group stage wrapped up - but who have been the stars of the show so far?

Unsurprisingly, Erling Haaland featured prominently, scoring half of Borussia Dortmund's goals as they topped Group F.

But what should we make of Lionel Messi, whose three goals all came from the penalty spot for Barcelona? And were Inter incredibly unlucky to bow out?

Using Opta data, we took a closer look at how Europe's elite performed.

Haaland's hammer blows

The Norwegian's left foot is about the deadliest weapon in world football at the moment and it comes as no surprise to see him topping the scoring charts with six goals in four games.

That put him alongside Paris Saint-Germain's Neymar, United's Marcus Rashford and Juventus striker Alvaro Morata, all of whom played more games and minutes than the Dortmund marksman.

Five of Haaland's goals came from his trusty left boot, and it continued his rich vein of form in Europe after he hit eight goals in six group games for Salzburg last season and two for Dortmund in the knockouts. The 20-year-old's Champions League goals this season have come at one every 57.5 minutes, and among players to have scored more than twice that minutes-per-goal mark was second only to Chelsea's Olivier Giroud (five goals, one every 28.4 minutes).

Yet when it came to overall goal involvements in this term's group stage, it was another Bundesliga star who led the way in Europe, with Alassane Plea of Borussia Monchengladbach tallying eight - five goals and three assists.

Germany had a productive group stage as Dortmund, Gladbach, RB Leipzig and holders Bayern Munich all reached the last 16 - the first time four teams from the Bundesliga have advanced since the 2014-15 season (Bayer Leverkusen, Dortmund, Schalke, Bayern).

Haaland would have been disappointed to see Salzburg bow out, however, with the Austrian side becoming just the second team to score 16 or more goals in the first group stage yet be eliminated, after Chelsea in the 2012-13 campaign.

Messi's mixed bag

For the first time since registering his first Champions League goal in 2005-06, Messi failed to score from open play in the group stage.

From highs of eight open-play goals in the 2014-15 and 2016-17 seasons, his number crashed to zero this time even though Barcelona qualified with ease for the knockout stage.

The 33-year-old Argentinian stuck away a group-stage high of three penalties - a total matched by Chelsea's Timo Werner and Lazio striker Ciro Immobile - to ensure it was not a complete goal famine.

Going goalless was not for the want of trying - Messi had seven shots on target in this week's 3-0 defeat to Juventus, which is more than any other player has had in a Champions League game without scoring since at least 2003-04.

He also created more chances across the six games than any other player, with Messi's total of 16 putting him one ahead of Ajax's Dusan Tadic and United's Bruno Fernandes, both of whom only have Europa League football to enjoy in the new year.

Of those chances, however, only two gave Messi assists. Leading the way on that score was Juventus' Juan Cuadrado, who set up five goals.

Barcelona created more chances than any other team (84), followed by Real Madrid (77), Sevilla and Bayern (both 73). Eventual champions Bayern had 106 chances in the group stage last year, as they set the high standard they maintained all the way through the competition.

Barcelona also had the most opportunities defined by Opta as 'big chances' over this season's six rounds of games, with 26. They converted 46.15 per cent of those openings, which ranked them eighth among teams to have at least 15 – United led the way by scoring from 68.75 per cent of their 16 such opportunities.

Were Inter framed?

Inter could not get the winner against Shakhtar Donetsk this week that would have carried them through to the last 16, with Lautaro Martinez hitting the bar early on, extending his run of bad luck.

The Argentine striker hit the goal frame four times in the group stage, more than any other player and the most by anyone across an entire Champions League season since Robert Lewandowski struck the woodwork five times for Bayern during 2016-17.

Martinez only scored once as Inter bowed out, unlike Lewandowski who put away eight goals in nine games during that campaign.

Inter hit the woodwork seven times in total over their six games, the joint-highest number along with Real Madrid.

Juventus attacker Juan Cuadrado cannot see Barcelona superstar Lionel Messi joining Cristiano Ronaldo at the Serie A champions.

Messi has sensationally told Barca he wants to leave the club, where the six-time Ballon d'Or winner has spent his entire professional career.

Manchester City, Paris Saint-Germain and Inter have been most strongly linked with moves for the 33-year-old.

Others have suggested Messi could join Ronaldo in Turin to bring together the two best players of the modern day, but Cuadrado would be surprised if such a move happened.

"I can't imagine it at all. The truth is that I don't," he told ESPN Nexo on Thursday.

Cuadrado added: "Just like with Cristiano, many people did not believe and suddenly he arrived."

Juve are preparing to begin their 2020-21 campaign under a new head coach after Andrea Pirlo replaced Maurizio Sarri at the helm earlier this month.

Cuadrado, who has been at Juve since 2015 and initially arrived on loan, said he was yet to hold talks with Pirlo about his plans.

"I have not had the opportunity to talk to him yet. When it is my turn I will surely tell him where I feel much more comfortable [playing]," he said.

"Hopefully what he knows and what a good player he was, he can contribute to the team and that we can get many titles together."

There was a predictable champion at the end of the 2019-20 Serie A campaign as Juventus clinched a ninth successive Scudetto, and their success is reflected in Opta's Team of the Season. 

Although Juve finished 2019-20 just a point ahead of second-placed Inter, they had wrapped up the title with two games to go – beating Sampdoria 2-0 on July 26.

Cristiano Ronaldo was unsurprisingly key, finishing as his team's top scorer, but for much of the season there were a few sides that looked like they might push Juve all the way.

Inter, Atalanta and Lazio all had their moments where they were able to dream and they each had individuals who impressed.

Following the conclusion on the campaign on Sunday, we teamed up with Opta to outline the Serie A Team of the Season.

OPTA'S SERIE A TEAM OF THE SEASON

GK: Wojciech Szczesny, Juventus

Poland international Szczesny has come a long way since struggling in the latter part of his Arsenal career. He was once again a dependable option between the posts, remaining first choice despite the return of Gianluigi Buffon. He ended the season with a 74.4 per cent save success rate, the best of the Serie A goalkeepers to have played 20 or more times.

RB: Juan Cuadrado, Juventus

Hardly the most convincing of defenders, granted, but Cuadrado boasts the versatility to play in a few roles down the right flank and he became an important figure for Maurizio Sarri – his 28 Serie A starts is just one fewer than he managed in the previous two seasons combined. The Colombian was certainly influential, too, as he was involved in more open-play sequences that ended with a shot made by someone else (132) than any other player this term. He also chipped in with two goals and five assists.

CB: Stefan de Vrij, Inter

No team conceded fewer goals in Serie A this season than an Inter side that Antonio Conte ensured was well-drilled. Netherlands centre-back De Vrij played a major role in that as he featured 34 times – though his efforts were not notable just for his defensive effectiveness. The former Feyenoord man scored three goals and also set up another three, making him the most productive centre-back in the league in this regard.

CB: Francesco Acerbi, Lazio

After Inter, the next-best defensive unit in Serie A was Lazio, who let in 42 (six more than Conte's men). Acerbi missed just two games all season and his form at the start of the season also saw him make three starts for Italy. The 32-year-old has proven himself to be one of Serie A's best stoppers, as evidenced by the fact he was dribbled past just six times this term. No other outfield player with more than 35 appearances did better than that.

LB: Theo Hernandez, Milan

Former France youth international Hernandez has rediscovered the early promise he showed during a fine loan spell at Deportivo Alaves in 2016-17. While question marks remain over his defensive abilities, the Atletico Madrid youth product has excited with his attacking tendencies in 2019-20. No defender completed more dribbles (57) than him, while he also had a hand in nine goals (six goals, three assists).

CM: Luis Alberto, Lazio

Since leaving Liverpool for Rome in 2016, Luis Alberto has arguably developed into one of the world's best creative midfielders. The Spain international sees passes few others can and he has put that to particularly good use in 2019-20, with his 106 chances created being a Serie A high. Similarly, his 15 assists was second only to Alejandro Gomez (16), as he helped Simone Inzaghi's men mount a title challenge. Often linked with a return home to Sevilla, Lazio will surely be doing everything they can to keep Luis Alberto at Stadio Olimpico.

CM: Fabian Ruiz, Napoli

The other half of a Seville-centric midfield, Real Betis product Fabian probably hasn't impressed quite as much as he did in 2018-19, but he has nevertheless continued to show plenty of promise. Still only 24, Fabian attempted the most passes (2,331) of any player in the league this season, while he had a hand in nine goals, the same amount as in the previous campaign.

AM: Alejandro Gomez, Atalanta

Like a fine wine, 'Papu' Gomez just seems to get better with age. Now 32, the Argentinian has enjoyed a fantastic season for the often-exhilarating Atalanta. He scored seven goals for a second successive season, but his haul of 16 assists is five more than 2018-19. That figure is the highest since Opta records began in 2004-05.

FWD: Paulo Dybala, Juventus

The Sarri-Juventus combination continues to puzzle many, but if there's one thing he has got right, it's helping Dybala get back to something resembling his best. He had been strongly linked with a move away last year, but Dybala was involved in 17 Serie A goals this term (11 goals, six assists) and managed to coexist with Ronaldo more effectively. Of his 11 strikes, eight (73 per cent) were the opening goals of matches, the biggest quantity among players with 10 or more.

FWD: Cristiano Ronaldo, Juventus

Considering there being murmurs of discontent between himself and Sarri, and suggestions the coach hasn't been able to get the best out of the Portugal great, Ronaldo's had a pretty effective year. With 31 league goals, it's been his best goal-scoring campaign domestically since getting 35 with Real Madrid in 2015-16, while his goals have secured 24 points, more than any other player.

FWD: Ciro Immobile, Lazio

What a season Immobile has had. With 36 league goals, the Italy international equalled Gonzalo Higuain's record for a single campaign, while that haul also won him the coveted European Golden Shoe. On top of that, his record of nine assists was bettered by only Gomez, Luis Alberto and Domenico Berardi. If he can keep it up, Lazio will surely fancy themselves of challenging Juve again next term.

Maurizio Sarri explained his decision to rest Cristiano Ronaldo for Juventus' 2-0 victory over Brescia, saying the 35-year-old forward "cannot play 75 games" a year.

Ronaldo was left out of the squad after scoring 10 goals in his previous six Serie A appearances to take his tally to 20 this season, but Paulo Dybala and Juan Cuadrado found the net in his absence on Sunday.

Sarri was also without injured quartet Douglas Costa, Federico Bernardeschi, Sami Khedira, and Merih Demiral, but Giorgio Chiellini made his first appearance since August as a second-half substitute.

Juve boss Sarri felt Portugal star Ronaldo needed time to put his feet up given the workload he has for club and country.

Sarri said: "It is difficult; we have many strong players and some are out.

"They are all atypical players, without a specific role. We have many situations to fix.

"Ronaldo is a centre-forward who starts off-centre. Today Cristiano had to rest; he cannot play 75 games there a year between the national team and the club, so we decided to let him recover."

On Chiellini, he added: "He put himself in the team. He had said it since yesterday. He made six months of great sacrifices."

Sarri admitted his side's performance against Brescia left plenty of room for improvement after seeing the Serie A champions pick up only their second win in five matches.

Defeats to Napoli and Hellas Verona either side of a victory over Fiorentina preceded Juve's 1-1 Coppa Italia draw with Milan ahead of the win over Brescia on Sunday, and they face SPAL on Saturday with Ronaldo set to play his 1,000th career game.

"We can improve on everything," said Sarri.

"On a defensive level we have room for improvement. We also have room for improvement in attack.

"We have hit the post five times in the last two games, so a little more luck would help us. We must focus on ourselves, instead of looking to others."

Paulo Dybala scored his sixth Serie A goal of the season and Juan Cuadrado was also on target as Juventus earned a 2-0 victory over 10-man Brescia that moved the Bianconeri top of Serie A ahead of Inter's evening kick-off at Lazio.

With in-form Cristiano Ronaldo rested by head coach Maurizio Sarri, Argentina international Dybala provided the firepower the champions needed from a first-half free-kick after Brescia forward Florian Aye was sent off.

Sarri's men were guilty of wasteful finishing against their 19th-placed visitors, who might have ground out a point towards their battle against relegation had they kept 11 men on the field, but Cuadrado kept his cool to double their lead after 75 minutes.

It was far from a vintage performance, but two goals proved enough to earn Juve a first win in three matches and relieve some of the pressure mounting around Sarri's position.

Giorgio Chiellini's appearance as a second-half substitute following a long injury lay-off also boosted the home crowd.

An early clash with Gonzalo Higuain left Brescia goalkeeper Enrico Alfonso unable to continue and he was replaced by the club's third-choice stopper Lorenzo Andrenacci after nine minutes.

But Brescia's impressive first half fell apart 10 minutes before the interval.

Aye brought down Aaron Ramsey on the edge of the box and received his second yellow card in four minutes, before Dybala curled a sublime free-kick into the left corner of the net with Andrenacci rooted to the spot.

Andrenacci kept the deficit to one goal at the break with a superb one-handed save, turning a Daniele Rugani header onto the crossbar when the Juve defender looked certain to score.

Leonardo Bonucci was denied early in the second half, Andrenacci parrying the Italy international's powerful header away from danger.

Dybala danced through the Brescia box after 66 minutes only to have his shot from 12 yards blocked by Birkir Bjarnason.

Bjarnason blazed over the crossbar when the ball fell to him unmarked on the edge of the box moments before Cuadrado made sure of the victory, playing a neat one-two with Blaise Matuidi and applying a cool, dinked finish past Andrenacci from six yards out.

Higuain saw a header disallowed for offside late on and Dybala hit the bar right at the death, with Juventus comfortable in the end.

What does it mean? Sarri keeps Pep talk on hold

A run of two defeats in three Serie A games handed the title race initiative to Inter and led to speculation that Pep Guardiola could replace Sarri at the end of the season.

While unspectacular, this win steadied the ship and reassured Juve supporters that their side are not reliant on Ronaldo to keep them winning.

Dybala does the business

It was an all-action performance from Dybala, who linked up with Cuadrado and Higuain to great effect throughout, took his goal superbly and rattled the crossbar with his rising drive on the stroke of full-time.

Clumsy Aye costs Brescia

Just four minutes after being booked for a needless foul on Danilo, Aye got his legs tangled up with Ramsey in a dangerous position, got himself sent off and conceded the free-kick from which Dybala scored.

What's next?

Ronaldo is in line to play his 1,000th career match as Juventus travel to Ferrara to face SPAL on Saturday, with Brescia hosting Napoli on Friday.

Juan Cuadrado was wrongly sent off as Juventus lost 3-1 away to Lazio in Serie A on Saturday, according to Maurizio Sarri.

The Bianconeri coach saw his side lose for the first time since his arrival despite Cristiano Ronaldo's goal putting the champions in front at the Stadio Olimpico.

Luiz Felipe headed Lazio's equaliser before the turning point of the match, Cuadrado seeing red after bringing down Manuel Lazzari as he ran through on goal.

Referee Michael Fabbri initially opted to book Cuadrado but then changed the yellow card to red after consulting pitchside monitors, and Lazio made the most of their man advantage.

Sergej Milinkovic-Savic brilliantly scored from Luis Alberto's lofted pass, and Felipe Caicedo struck deep in added time to secure Lazio's first home league win over Juve since 2003.

"We didn't respect our duties, because players were in the wrong position," Sarri told DAZN of the incident leading to Cuadrado's dismissal. "It was a distraction and you pay for that.

"We had decided before the game on certain positions and we didn't cover them.

"I do not entirely agree that it was a clear scoring opportunity, as the ball was going wide. I thought a yellow card was the right ruling, but the fact remains that is out of our control and we made a mistake to create the situation."

Sarri, who said Rodrigo Bentancur needs tests on a ligament injury, felt there were positives to take from Juve's performance despite a second straight league game without a win.

"In the second half, when the game seemed to be in a more balanced state, the red card changed everything," he said. "We lost the match, but, to be honest, I saw improvements in my team."

Lazio have won seven games in a row in Serie A and are only five points behind leaders Inter, prompting suggestions they could be in the title race.

They last won the league 20 years ago, and coach Simone Inzaghi feels topping the table may be a realistic target for his impressive side.

"We are in a great period of form," he told DAZN. "We should be ambitious, knowing also that six weeks ago people said we weren't getting results but I remained calm.

"The club was always close to me, even when we lost, reassuring me there were no problems.

"I also have a squad that is always at the disposal of my staff and I. Now we enjoy this victory, which we hadn't managed for 16 years here, a game I remember, because I was on the bench.

"We enjoy it for a few hours, but from Thursday we must get right back on track and aim to stay in the Europa League. We played well, created many chances and could have scored more goals, so I praise these lads for something extraordinary."

Sergej Milinkovic-Savic and Felipe Caicedo netted as Lazio came from behind to shock Juventus 3-1 at home and inflict Maurizio Sarri's first defeat as Bianconeri coach.

Juve, held 2-2 at Sassuolo last time out, took the lead through Cristiano Ronaldo but were pegged back before the break by Luiz Felipe's header in a gripping Serie A encounter.

Juan Cuadrado's red card opened the door for Lazio and they charged through it, Luis Alberto setting up Milinkovic-Savic for a superb strike to edge in front.

There was time for more drama, though, Juve goalkeeper Wojciech Szczesny saving Ciro Immobile's penalty, and Caicedo added a third deep in added time to leave Inter two points clear at the top.

Winger Juan Cuadrado has signed a two-and-a-half-year contract extension at Juventus, the Serie A champions have confirmed.

The 31-year-old Colombia international joined Juve initially in August 2015, in the first of two consecutive season-long loans from Chelsea.

A permanent €20million switch was finally secured ahead of the 2017-18 season.

Cuadrado has won the Scudetto in each of his four seasons in Serie A, along with three Coppas Italia and a Supercoppa Italiana.

The former Fiorentina man has 15 goals and 28 assists in Juve colours, although he has generally been more concerned with defensive duties this season.

Injury problems forced Maurizio Sarri to field Cuadrado as a full-back, and the majority of his 14 appearances in all competitions this term have come on the right-hand side of defence.

Cuadrado is the second senior member of Juventus' squad to pen fresh terms this week after Italy centre-back Leonardo Bonucci renewed until June 2024.

Juan Cuadrado expects Antonio Conte's fast-starting Inter to pose a genuine Serie A title threat to Juventus this season.

Inter overcame Alexis Sanchez's red card to beat Sampdoria 3-1 on Saturday and extend their winning start to six matches.

Juve earlier saw off SPAL 2-0 in Turin but remain two points adrift of the leaders ahead of next Sunday's crucial top-of-the-table clash at San Siro.

Colombia international Cuadrado has seen enough from the Nerazzurri to know his team will not be allowed to cruise to another Scudetto.

"Inter are a great team," Cuadrado told Sky Sport Italia.

"They have everything [required] to be up there. We have to keep fighting to stay ahead. It will be a great battle next Sunday and we hope to be at 100 per cent."

Cuadrado, 31, completed 90 minutes at right-back against SPAL, plugging a defensive gap following injuries to Danilo and Mattia De Sciglio.

Though naturally a winger, he will likely have to continue at the back until after the international break.

Cuadrado believes the recently retired Andrea Barzagli's return to the club in a technical coaching role can help hone the defensive side of his game.

"I've always played on the wing but I'm at the coach's disposal to give everything I can," the former Fiorentina and Chelsea man said.

"Even more so in this moment of emergency, I will try to give my best and do the defensive phase well.

"I've already talked with Barzagli about it. His experience will surely help."

Before the Inter match, Juve must negotiate a Champions League meeting versus Bayer Leverkusen on Tuesday.

Maurizio Sarri's men squandered a two-goal lead in drawing 2-2 at Atletico Madrid in their Group D opener.

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