The Denver Nuggets are on the brink of sweeping the Los Angeles Lakers after opening up a 3-0 lead in the teams' first-round series on Thursday, registering their 11th straight win against them.

Aaron Gordon had a playoff career-high 29 points and added 15 rebounds, while Nikola Jokic was just short of a triple-double with 24 points, 15 rebounds and nine assists as Denver clinched a 112-105 win.

Having squandered a big lead in Game 2, the Lakers failed to respond at home as the Nuggets began the second half with a 24-10 run to pull away from their hosts. Los Angeles failed to get closer than eight points in the fourth. 

LeBron James had 26 points, six rebounds and nine assists, while Anthony Davis had 33 points and 15 rebounds, but Los Angeles were let down by their shooting from the field.

They shot just 5 of 27 from the floor, missing with 15 of their first 16 3-point attempts. 

Game 4 takes place at Crypto.com Arena on Saturday, with the Lakers needing to become the first team in NBA history to rally from a 0-3 playoff deficit to keep James' 21st season alive. 

A small group of home fans showed their displeasure with head coach Darvin Ham after the loss, staying behind to chant, "fire Darvin" as the rest of the crowd filtered out.

Embiid's half-century takes Knicks-Sixers to 2-1

Joel Embiid's huge 50-point haul breathed fresh life into the Philadelphia 76ers' series with the New York Knicks, bringing the Sixers back to 2-1 after two road losses to start the playoffs.

The 76ers triumphed 125-114 as Embiid became the first player in playoff history to score 50 points on fewer than 20 shots in a game, going 13 of 19 from the floor and making 19 of 21 free throws.

Philadelphia were three down at the half but produced a huge third quarter, Embiid dragging his team into a 98-85 lead with four 3s in that period.

Tyrese Maxey supported Embiid with 25 points and seven assists, after the NBA admitted the officials missed a foul on him in the closing stages of the Sixers' controversial Game 2 loss.

Jalen Brunson led the Knicks with 39 points and 13 assists while Josh Hart tacked on 20 points, but Donte DiVincenzo only had five after hitting the decisive 3-pointer in Game 2.

Cavs suffer worst playoff loss as Magic hit back

The Orlando Magic also hit back after losing the first two games of their first-round series, dealing the Cleveland Cavaliers the heaviest loss in their playoff history on Thursday.

Taking the series back to Kia Center after a pair of road losses, Orlando recorded a 121-83 win behind Paolo Banchero's 31 points, with Jalen Suggs adding 24 for the fifth seeds in the East.

Orlando led by as many as 43 points in the fourth quarter before ultimately settling for a 38-point margin. The Cavs' previous worst playoff loss was a 36-point defeat to the Washington Wizards in 2008.

Franz Wagner tacked on 16 points and eight assists for Orlando, who now have the chance to level the series at home in Game 4 on Sunday.

Cleveland had four players in double figures but none managed more than the 15 put up by both Jarrett Allen and Caris Levert, the visitors shooting a miserable 8 of 34 (23.5 per cent) from the floor.