William Saliba's red card marked Arsenal's third dismissal in just eight Premier League games, leaving Mikel Arteta frustrated by the mistakes that led to their 2-0 defeat to Bournemouth.
The France centre-back was sent off following a VAR review in the 30th minute for bringing down Evanilson and denying him a goalscoring opportunity.
Despite digging in, Arsenal were unable to maintain their unbeaten start, as Ryan Christie and Justin Kluivert's second-half goals subjected them to a first defeat of the season.
It is the first campaign since 2011-12 that the Gunners have had as many as three players sent off in their opening eight matches of a Premier League season.
In fact, since Arteta's first game in charge of Arsenal on Boxing Day 2019, they have been shown 18 red cards in the top flight, at least five more than any other side.
While they managed to hold onto results against Brighton and Manchester City after going down to 10, Arteta admitted it was going to cost them eventually.
"It's very difficult to win in the Premier League with 10 men for 60-70 minutes, it's just an accident waiting to happen. We have had to go through it in three games and that cost us the game," he told BBC Match of the Day.
"We had the big chance and the moment in the game to score and have a different result, and then we conceded a goal. We try to stick to the rules. The three [red cards] have been different ones and three very different outcomes.
"The team tried, the effort with 10 men was fantastic, but today it was not enough to win the game. It took us a while to understand what we had to do in the first 15 minutes to start with, then we grabbed the game, but after 30 minutes, the game changed."
Bournemouth secured just their second-ever Premier League victory over Arsenal in 15 meetings, and their first since January 2018, when they won 2-1.
Andoni Iraola's substitutes did the damage for the Cherries, with Kluivert both scoring and assisting in a Premier League game for the first time.
Iraola was delighted by the maturity shown in his team's performance as they bounced back from a disappointing loss to Leicester City before the break.
"It was quite a mature win because it is a tricky situation [playing against 10 men]," Iraola told Sky Sports.
"We started well for the first 30 minutes and then the red card changes the game. We had to control the game, attack but not lose our minds, as even with 10 men, set plays, free-kicks they could be a threat. Luckily for us, we took the benefit of having one man more.
"Before half-time, we missed a couple of chances and at the beginning of the second half we managed not to finish, so we had to have patience to take the benefit of having one more player without losing our heads.
"We were playing very well the first 30 minutes. It was a very level game, which is very good when you face this opposition. It became easier with 11 v 10 but everything is not done, you have to finish the job, and we did it."
Cuba overturn deficit in 5-2 aggregate Play-In win over St Kitts and Nevis to book Gold Cup prelims spot
Cuba booked their spot in the Concacaf Gold Cup prelims after they turned the tables on St Kitts and Nevis in their Concacaf Nations League Play-In tie on Monday.
Needing to overturn a deficit from their 1-2 first-leg loss, Cuba did just that in commanding fashion as they blanked St Kitts and Nevis 4-0 in a lopsided return-leg encounter at Estadio Antonio Maceo in Santiago de Cuba.
After bossing possession for most of the first half, Cuba inevitably broke the deadlock when Onel Hernandez produced a decent solo run on his way to driving home a right-footer from the top of the penalty area to level the series on aggregate at that point.
But the hosts were far from done and doubled the lead on the stroke of the break as Yosel Piedra also converted from close range in the 45+3 to make it 2-0 at the break and 3-2 on aggregate.
With St Kitts and Nevis offering very little resistance on the resumption, Cuba extended their lead in the 50th courtesy of Luis Paradela’s close-range finish.
Maykel Reyes then converted an 87th-minute penalty to cap the win as Cuba continued their march towards making the cut for next year’s Concacaf Gold Cup. A win in the preliminary rounds would see them achieving that feat.
Bayern's Palhinha sidelined for weeks with adductor injury
Bayern Munich confirmed Joao Palhinha will be sidelined for several weeks after suffering an adductor injury while on international duty.
The midfielder sustained the issue while training with Portugal, and withdrew from the squad, missing both of their Nations League fixtures against Poland and Croatia.
Palhinha, who joined Bayern on a four-year contract in July from Fulham, has made 13 appearances in all competitions and boasts a 100% tackle completion rate in the Bundesliga (7/7).
"FC Bayern's medical department has confirmed that Joao Palhinha suffered a torn muscle fibre in his right adductor while training with the Portugal national team," the club said. "The midfielder will therefore be sidelined for the coming weeks."
Bayern have been boosted by Aleksandar Pavlovic's return to first-team training over the international break, though he has still not returned to full fitness.
The Bavarians, top of the Bundesliga with a five-point advantage over RB Leipzig, have a busy schedule ahead of them with four matches in 11 days.
Bayern take on Augsburg in the league on Friday before hosting Paris Saint-Germain in the Champions League next Tuesday. They then travel to Borussia Dortmund in the Bundesliga and face holders Bayer Leverkusen in the DFB-Pokal on December 3.
Curacao secure League A promotion, Gold Cup berth after 4-1 win over St Lucia in Group B
Curacao secured promotion to League A and direct qualification for next year’s Concacaf Gold Cup after they topped Group B of League B in the Concacaf Nations League action on Monday.
The Dutch-speaking Caribbean Island bettered St Lucia 4-1 in their top-of-the-table clash at the Ergilio Hato Stadium in Willemstad, Curaçao.
Gervane Kastaneer opened the scoring in the 27th with a tidy finish on the volley as he connected well from Jearl Margaritha’s weighted cross.
St Lucia pulled level in the 29th courtesy of Ryan Charles, who won possession at the top of the penalty area and finished at close range.
However, Kastaneer grabbed his brace to put Curacao back on top as he produced another decent close range finish to make it 2-1 at the break.
Any hopes St Lucia had of a comeback were dashed in the 73rd when Juninho Bacuna displayed nippy footwork to dismiss markers and slot home.
Bacuna then completed his brace and Curacao’s rout when he fired home in the 79th to secure their promotion to League A and, by extension, a berth in the Gold Cup.
They topped the group with 13 points, four more than St Lucia (nine points), while Grenada, who were 3-0 winners over St Martin in the other group contest, ended on seven points.
Rahim Dennis (39th) and Keelan Lebon (87th and 90+3) sealed Grenada’s win against St Martin to ensure they stay up in League B for another edition.
By virtue of that loss, St Martin, who finished last on the four-team standings on six points, have been relegated to League C for the next edition of the Nations League.
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