Marco Silva conceded Fulham "cannot switch off for one second" in the Premier League, after Danny Ings' last-gasp equaliser denied the Cottagers all three points against West Ham.
The hosts appeared on course to take the spoils in the London derby at Craven Cottage, where Raul Jimenez put them in front after 24 minutes.
However, the visitors snatched a dramatic equaliser in the fifth minute of stoppage time, when substitute Ings fired past Fulham goalkeeper Bernd Leno.
And Silva acknowledged his side's brief lapse in concentration proved costly.
"It just shows that in this Premier League, you cannot switch off for one second," he told BBC Sport. "We are aware of the quick throws, and we have to keep focus and concentration.
"A big frustration for us because, before that, it was a good performance. It was clear we were the best team on the pitch. They did not have one shot [on target] in the first half.
"We should have won this game. It was not a game where West Ham pushed us back. The goal came after we switched off. It just shows you have to keep focus until the last second."
Silva also felt Fulham should have been awarded a first-half penalty when Adama Traore was challenged by Max Kilman.
"It was a clear, clear, penalty in my opinion," he added. "It's difficult to understand why it was not a penalty in that situation. I don't even want to say anything more about it."
Meanwhile, West Ham boss paid tribute to Ings, who was making only his second Premier League appearance of the season - with both coming as a late substitute.
"It was a very 'Danny Ings' goal!", Lopetegui told West Ham's official website. "He is always agile in those kinds of actions, and he took his chance very well.
"I'm really happy for him, because he hasn't played much up until now, but he is always ready to go. He is a really good example to all of his team-mates, and it's great to see his work pay off.
"As a player, it can be hard when you don't know when the coach is going to call you. The important thing is to try and always be ready, because you are going to be needed at some point.
"Scoring in the last minute today is important, because he's shown everyone that you have to believe until the end. Even though there were things we could do better today, we kept going, and we got something out of the game."
Shaw, Layzell on target as Man City stun holders Barcelona in Women's Champions League
Naomi Layzell enjoyed a dream Women's Champions League debut as her goal and assist helped Manchester City stun holders Barcelona 2-0 on Wednesday.
Layzell was playing her football in the Women's Super League last season with relegated Bristol City, but was the star of the show at the Joie Stadium.
City were making their first appearance in the competition since falling to a 4-2 quarter-final loss to the Catalan side in March 2021, and exacted their revenge with a plucky display.
The hosts, however, almost found themselves a goal behind with just three minutes on the clock when Caroline Hansen took aim and saw her effort cannon off the post, shortly before Lauren Hemp struck the woodwork with a strike of her own.
City grew into the contest and almost got the goal their performance merited in the 35th minute when Vivianne Miedema teed up Khadija Shaw, only to see her effort saved by Cata Coll.
But from the resulting corner, Gareth Taylor's side got their noses in front as Miedema brilliantly headed the ball from the back post and back into the danger area, with Layzell sliding in to mark her Champions League debut with a goal.
Barcelona had only failed to score once in their past 79 games heading into the encounter, and improved after the interval in their search for an equaliser.
Aitana Bonmati forced Ayaka Yamashita into making a smart save down to her right, with substitute Claudia Pina going close from distance as City were forced to withstand a relentless wave of pressure from the defending champions.
But the hosts landed a sucker punch in the 77th minute on the counter, with Layzell turning provider for Shaw, with the striker riding the challenge of Patri Guijarro before rounding Coll to seal a memorable triumph for City.
The Citizens ended the contest with an expected goals (xG) total of 1.68 compared to Barca's 1.5, despite having four fewer shots than their opponents.
Gareth Taylor's side sit level on points with Hammarby in Group D, after the Swedish side beat Austria's St. Polten 2-0 earlier on Wednesday.
Meanwhile, in Group C, Juventus edged out Norwegian side Valerenga to kickstart their campaign with a victory at the Intility Arena.
Sofia Cantore's 29th minute strike proved to be the difference, with the Italian curling a fine right-footed effort beyond the grasp of Tove Enblom against the run of play.
Juventus continued to struggle throughout the contest, with Valerenga registering 25 shots, with six of those on target, ending with an xG total of 2.2.
Man United's Diallo withdraws from Ivory Coast squad
Manchester United's Amad Diallo has withdrawn from the Ivory Coast's Africa Cup of Nations qualifying double-header against Sierra Leone due to illness.
Diallo, who has made six appearances for his country, has since returned to Manchester ahead of the Red Devils' upcoming Premier League fixture against Brentford.
The 22-year-old earned his first cap for the Elephants in 2021, and was recalled to Emerse Fae's group after a 15-month absence in June for wins over Zambia and Chad.
Ivory Coast know that two wins against the Leone Stars will seal their progression to the tournament, which takes place in Morocco at the end of next year.
A statement by the Elephants read, “The Ivorian Football Federation informs the Press and the public that the player, Amad DIALLO, arrived in group on Monday October 7, 2024, as part of the 3rd and 4th Days of the CAN qualifiers Morocco 2025, is declared forfeit for health reasons.”
Diallo is the latest player within Erik ten Hag's ranks to withdraw from international duty with their respective nations.
Argentina's Alejandro Garnacho, England's Kobbie Mainoo and Morocco's Noussair Mazraoui are the other players left out as a precaution.
Diallo has made 10 appearances for United this season in all competitions, scoring once in his side's 2-1 defeat to Brighton at the start of the 2024-25 campaign.
However, he has yet to fully nail down a starting berth, with Ten Hag so far rotating his wide options with Garnacho and Marcus Rashford.
Daniel Maldini the missing piece to Italy puzzle, believes Spalletti
Italy head coach Luciano Spalletti believes Daniel Maldini has been the creative spark the national side has been lacking ahead of their Nations League clash with Belgium.
Maldini could follow in the footsteps of his father, Paolo, and grandfather Cesare, both former Italy captains, should he represent the Azzurri at the Stadio Olimpico on Thursday.
The 22-year-old came through the ranks at Milan, managing 24 appearances in all competitions and scoring once, but spent three seasons out on loan from 2022 to 2024.
Maldini spent the second half of last season on loan with Monza before making his move permanent in July, netting five goals in 19 outings to help Raffaele Palladino's side to a 12th place finish in Serie A.
Now under the guidance of Alessandro Nesta, Maldini has begun to flourish, completing more dribbles (12) than any of his team-mates in the league so far.
The young Italian was one of four players given their senior call-up by Spalletti for their Nations League fixtures against Belgium and Israel, with the Monza forward replacing Lazio's Matteo Zaccagni.
And Spalletti is confident Maldini can make an impact, saying: "He is the (kind of) player we were missing."
Italy come into the contest off the back of an impressive opening to their Nations League A2 group, beating Israel and France last month.
After a disappointing Euro 2024 campaign that saw them lose to Switzerland in the round of 16, Spalletti insisted that their encounter against Belgium is crucial to their development.
"We will immediately become a great team in every match where we will be able to give the best of ourselves," Spalletti said.
"It is a crucial match for our future."
Spalletti, however, has his eyes set on the 2026 World Cup, a tournament the Azzurri have won on four occasions throughout their history.
But Italy failed to qualify for the 2018 and 2022 editions of the competition, but have since won the European Championships against England in 2021 under Roberto Mancini.
While Spalletti signified the importance of the World Cup's influence on the Azzurri's illustrious history, he said his players must focus on each game as it comes.
"It is a tournament that has determined our history, it has made many people happy," Spalletti concluded.
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