The striker revealed his decision to don the green jersey for a final time ahead of a friendly against Oman taking place the following week.
In a statement, the-then 36-year-old said: “I had always hoped this day would never come and I will miss putting on the Ireland jersey and walking out to a sea of green.
“But I am looking forward to the game against Oman and putting on the jersey and singing the national anthem one last time in front of the home crowd at the Aviva.
“It will be an emotional night for me, but I will savour each and every last moment.
“While this is the end of my international career, I hope to continue to play for some years yet. I love my time playing with LA Galaxy and intend to focus my energies on continuing my club football for a few more seasons.”
Keane made his 146th and final international appearance, where he scored a volley as Ireland beat Oman 4-0.
His goal brought to an end an 18-year career with his country and took him level with German great Gerd Muller on 68 international goals.
Having played for clubs including Tottenham, Liverpool and LA Galaxy, Keane then retired from football in 2018.
Coaches including Jose Mourinho, Fabio Capello, Zinedine Zidane, Carlo Ancelotti, Gareth Southgate and Fabio Capello have joined the 24-man UEFA football board, along with superstar former players Paolo Maldini, Luis Figo, Gareth Bale, Rio Ferdinand, Michael Laudrup, Philipp Lahm and Robbie Keane.
There is one non-European on the board, with Inter's Argentine vice-president Javier Zanetti joining a throng that also includes former Germany team-mates Rudi Voller and Jurgen Klinsmann, plus Netherlands boss Ronald Koeman, Rafael Benitez, Patrick Vieira and Eric Abidal.
The noticeably all-male board will hold its first meeting at UEFA's European House of Football headquarters on Monday.
European football's governing body said the group will "give an institutional yet independent voice of experience and expertise on fundamental football-related topics".
UEFA president Aleksander Ceferin said: "UEFA is delighted to see that the very ones who have shaped the game's history with their talents and philosophy through decades are gathered again around our common goal – to protect the game of football and its essential values. As we always say: football first!"
Ceferin is campaigning for clarity on football's handball rules, having recently described the law as "really obscure".
"No one understands it any more," Ceferin said. "So we really need a conversation here, finding solutions and clarifying some issues."
He said that would be an issue for the football board to look at, and it was confirmed on Thursday as being on the agenda for the meeting, along with discussions about the video assistant referee system, player behaviour and medical issues.
UEFA said its technical director and chief of football Zvonimir Boban would chair Monday's meeting, although he is not a member of the new board.
UEFA football board members: Jose Mourinho (Portugal), Carlo Ancelotti (Italy), Zinedine Zidane (France), Paolo Maldini (Italy), Fabio Capello (Italy), Javier Zanetti (Argentina), Luis Figo (Portugal), Philipp Lahm (Germany), Ronald Koeman (Netherlands), Gareth Southgate (England), Rio Ferdinand (England), Michael Laudrup (Denmark), Rafael Benitez (Spain), Roberto Martinez (Spain)
Predrag Mijatovic (Montenegro), Jurgen Klinsmann (Germany), Rudi Voller (Germany), Petr Cech (Czech Republic), Juan Mata (Spain), Robbie Keane (Republic of Ireland), Patrick Vieira (France), Henrik Larsson (Sweden), Eric Abidal (France), Gareth Bale (Wales).