Charlton, who also took 100m hurdles silver at the 2022 Commonwealth Games in Birmingham, won ahead of Americans Tia Jones (7.80) and Masai Russell (7.88).
She also took the 60m hurdles at the UK Rod McCravy Memorial in Louisville in 7.88 on January 13.
Elsewhere on the track, Jamaican Texas Tech sophomore and former Wolmer’s Boys and Kingston College standout Shaemar Uter ran 46.04 for second in the men’s 400m behind Oklahoma senior Zarik Brown (46.03). Dubem Nwachukwu, running unattached, was third in 46.30.
In the field, Kentucky junior Luke Brown jumped 16.80m to win the men’s triple jump ahead of Miami’s Russell Robinson (16.59m) and Texas Tech’s Garison Breeding (15.82m).
Ralford Mullings threw 18.58m for top spot in the men’s shot put ahead of Baylor’s Gary Moore (18.20m) and Miami’s Milton Ingraham (18.07m).
Texas A&M’s Distin, who has yet to lose indoors this season, jumped 1.97m to win ahead of teammate Bara Sajdokova who produced 1.87m while Georgia’s Elena Kulichenko jumped 1.84m for third.
Distin’s mark equals her own outdoor national record which she did on her way to winning gold at the NCAA Championships.
The 2022 Commonwealth Games gold medallist has now achieved winning clearances this season of 1.90m at the Razorback Classic on January 27, 1.94m at the New Mexico Collegiate Classic on February 3 and 1.97m on Saturday.
Elsewhere, 2019 World Championships shot put silver medallist Danniel Thomas-Dodd threw 18.74m to comfortably win the event ahead of Hannah Hall who threw 16.71m and Ana da Silva who threw 16.60m for third.
Jamaicans also occupied the top two spots in the Men’s triple jump as Virginia’s Owayne Owens produced 16.59m for victory ahead of Kentucky’s Luke Brown who produced 16.43m. Ohio State’s Clarence Foote-Talley was third with 15.88m.
Lyston, who earlier this season claimed both the SEC and NCAA Indoor 60m titles, produced her first sub-11 time to finish in a close second behind Favour Ofili of Tiger Olympians who won in 10.85.
McKenzie Long of Ole Miss was third in 10.89.
Interestingly, this was Lyston's first 100m race since the Class One final at the 2022 ISSA/GraceKennedy Boys and Girls Championships.
Elsewhere, LSU’s Jahiem Stern ran 13.43 for third in the men’s 110m hurdles behind the Texas A&M pair Jaqualon Scott (13.34) and Connor Schulman (13.42).
Mississippi State’s Tyrese Reid ran a personal best 1:45.76 for second in the men’s 800m won by Texas A&M’s Sam Whitmarsh in 1:44.46.
Marcus Dropik of Ole Miss ran 1:47.82 in third.
In the field, Kentucky’s Luke Brown produced 16.40m to take the win in the men’s triple jump ahead of Ole Miss’s Iangelo Atkinstall-Daley (15.25m) and Georgia’s Zavien Wolfe (14.84m).