Diego Schwartzman

"There is a lot of work, a lot of sacrifice and I think some tears left in my eyes," the 19-year-old said during his on-court interview.

"I'm really proud of myself, but now I'm going to work harder and focus on the next days."

Musetti, whose forehand was excellent, defeated both Stan Wawrinka and Kei Nishikori at the Internazionali d'Italia in Rome last year.

Top seed Stefanos Tsitsipas had no such trouble, easing into the second round, where he will face big-serving American John Isner.

The Greek world number five beat France's Benoit Paire 6-3 6-1, aided by a strong display on serve.

"I didn't know what to expect from Benoit today," Tsitsipas said. "I think it's kind of tricky playing a tournament you haven't played before."

On facing 27th-ranked Isner next up, Tsitsipas added: "He's a guy that serves really well so that's going to be the biggest element and the one thing that I'll really have to resolve during that match."

Fourth seed Milos Raonic sent down 13 aces as he defeated American Tommy Paul 7-6 (8-6) 6-4.

In the late match, fifth seed Grigor Dimitrov got past Adrian Mannarino, who retired when trailing 6-4 3-0.

The trio join Denis Shapovalov, Felix Auger-Aliassime and Diego Schwartzman for the team event which runs from September 24-26 at TD Garden in Boston.

Laver Cup newcomer Opelka rose to a career-high world number 23 ranking en route to his first ATP Masters 1000 final in Toronto and defeated world number three Stefanos Tsitsipas, who will play for Bjorn Borg's Team Europe.

Isner, who has featured for Team World since the inaugural event in 2017, reached the semi-finals in Toronto and claimed his 16th ATP Tour title in Atlanta at the start of August.

He described the Laver Cup as "a highlight of my year", adding: "To be on a team with guys we're normally competing against is so different and so much fun. We come together so well as a group, the chemistry is awesome and it's such a great environment to be part of."

Australian firebrand Kyrgios is a striking inclusion in Team World's roster, while Team Europe will be without their big three: Roger Federer, Rafael Nadal and Novak Djokovic.

Federer and Dominic Thiem were expected to take part in this year's event, though both were forced to withdraw with injuries.

However, Borg's men still boast six of the world's top 11. World number two Daniil Medvedev leads the line-up, with Tsitsipas and Tokyo Olympics gold medallist Alexander Zverev for company.

Casper Ruud, who collected a 14th win in his last 15 completed matches on tour when he beat Opelka on Wednesday, will feature, while Andrey Rublev and Wimbledon finalist Matteo Berrettini complete the six-man team.

Team Europe have landed the title in each of the three editions of the tournament so far, with Prague, Chicago and Geneva having served as hosts.

The enigmatic Australian triumphed 6-3 6-0 in 52 minutes to clinch a third round clash with Italian Fabio Fognini, who won in three sets against Japanese Taro Daniel.

The victory marks Kyrgios' third win over a top 10 opponent in the past two tournaments, having topped both Casper Ruud and Jannik Sinner at Indian Wells earlier this month.

Rublev had won titles in Marseille and Dubai earlier this season but was not allowed to settle by Kyrgios who sent down 10-5 aces and had a first serve percentage of 80 per cent.

"I know that he's a player who relies on a bit of rhythm, so I just tried to keep the points short and sharp, just play aggressive," Kyrgios said after the match.

"I'm just happy with my performance, whether it's 7-6 in the third or something like this, I'm just happy to get through."

Second seed Alexander Zverev was made to work for victory against Croatian Borna Coric, winning 6-4 3-6 6-3 in two hours and one minute.

The win marks the 2018 Miami Open runner-up's first triumph at the event since that run to the final.

Sixth seed Ruud eased past Henri Laaksonen 6-1 6-2, while ninth seed Sinner defeated Emil Ruusuvuori 6-4 3-6 7-6 (10-8) in two hours and 40 minutes.

Several seeds were beaten included 13th seed Diego Schwartzman who went down 4-6 7-6 (7-3) 6-4 to Thanasi Kokkinakis. Seeds Lorenzo Sonego, Grigor Dimitrov, Reilly Opelka and John Isner also exited.

Gael Monfils defeated Oscar Otte 7-6 (11-9) 6-1, Pablo Carreno Busta won 6-3 6-2 over David Goffin and 10th seed Cameron Norrie won 7-6 (7-5) 6-4 over Jack Draper.

Opening-day honours went to Bjorn Borg's Team Europe at TD Garden in Boston, where the defending champions moved into the box seat thanks to wins for Andrey Rublev, Matteo Berrettini and Casper Ruud in the singles on Friday.

John Isner and Denis Shapovalov managed to get Team World on the board in the evening's final doubles match against Alexander Zverev and Berrettini 4-6 7-6 (7-2) 10-1.

Roger Federer and Rod Laver were in the crowd as Team Europe – headlined by newly crowned US Open champion Daniil Medvedev and consisting of six of the world's top 10 – made a strong start courtesy of Norwegian Ruud, who overcame Reilly Opelka 6-3 7-6 (7-4), improving his career record to 3-0 against the towering American, and beating him in straight sets for the first time.

Italian star Berrettini then overcame Team World's Felix Auger-Aliassime 6-7 (3-7) 7-5 10-8 in the competition's longest match at two hours, 52 minutes.

Berrettini escaped with the second set after facing two break points in the penultimate game before prevailing against the Canadian in a thrilling match tie-break.

"One of the best matches bar none that I've ever seen played, absolutely just enthralling," said captain John McEnroe, whose Team World are eyeing their first Laver Cup trophy.

Rublev rallied past Argentina's Diego Schwartzman, who won the opening set and led 6-2 and 8-5 in the match tie-break before losing 4-6 6-3 11-9.

"Today we are a bit more lucky; Matteo won a tough match against Felix in a super tiebreak, now you saw my match," said Russian star Rublev.

"It was so close; Diego was leading all the super tiebreak, but in the end I find a way to win.

"This happens. This is tennis, this is sport. It’s emotions. Someone has to win, someone has to lose."

On day two, Stefanos Tsitsipas and Zverev headline the day session against Team World's Nick Kyrgios and Isner.

In the evening, Medvedev will meet Shapovalov before Rublev and Tsitsipas team up for a doubles battle with Kyrgios and Isner.

Londero progressed to the last eight of the ATP 250 tournament thanks to a 6-3 6-3 win over Argentinian compatriot Pedro Cachin on Thursday.

Cordoba was the scene of Londero's breakthrough ATP Tour title last year, the Argentine player capping a fairytale week by overcoming countryman Guido Pella in three sets.

Next up for Londero on the red clay is Serbian fourth seed Laslo Djere, who beat Spanish qualifier Pedro Martinez 6-3 6-4.

"I was a little nervous and that's why I talked to myself a lot and that's how I got in the game. The way I have to activate [myself] is by encouraging myself a lot. If I keep quiet, that doesn't happen. It was a game with many nerves for me, and I am glad I won it in straight sets," Londero said.

"For me, it is more a motivation than a pressure to play in Cordoba and try to defend the title. If I had to defend the tournament elsewhere, without having the support of my family, my friends who can see me live, the truth is that I think it would be more difficult anywhere else. I have been having a good time."

Albert Ramos-Vinolas – the fifth seed – outlasted Pablo Andujar 6-3 6-7 (4-7) 6-4 to set up a clash with Schwartzman, who defeated Jaume Munar 6-1 7-5.

World number one Medvedev fought back from a set down to defeat Aslan Karatsev 3-6 6-4 6-2 and advance to a quarter-final against fifth seed Roberto Bautista Agut, who was granted a walkover after Nick Kyrgios pulled out with an abdominal issue. 

The Russian got just 48 per cent of his first serves in during a blustery opening set before improving to 68 per cent in the second and controlling the decider as Karatsev struggled with injury. 

"It was tough to play [in] rhythm. It felt like many points were just whoever managed to put the ball in the court was going to win the point," Medvedev said of the tricky conditions. 

"It was not easy but I'm happy to win because that's the most important [thing]. 

"Last year was amazing. I played great tennis. Hopefully I can do the same this year. I like it here in Mallorca, so hopefully I can stay as long as possible in the tournament." 

Alongside Medvedev and Bautista Agut, Stefanos Tsitsipas is the only other seed left in the draw after he overcame Ilya Ivashka 6-4 6-4. 

Denis Shapovalov was a 6-4 6-1 loser against Benjamin Bonzi, Pablo Carreno Busta went down 6-3 6-4 to Antoine Bellier and Sebastian Baez's meeting with Daniel Altmaier ended in a 6-2 2-6 6-4 defeat for the Argentine. 

At the Eastbourne International, second seed Sinner suffered a 6-3 3-6 6-3 loss to Tommy Paul as he made his return from a knee injury sustained at the French Open.

World number 13 Sinner remains without a grass-court win in his ATP Tour career, while Paul will next face defending champion Alex de Minaur, who overcame Lorenzo Sonego 7-6 (7-3) 6-2 in a repeat of last year's final. 

Jack Draper defeated fourth seed Diego Schwartzman 7-5 7-6 (7-3) to advance to the quarter-finals and Cameron Norrie cruised past Brandon Nakashima in straight sets.

There were also wins for Maxime Cressy, Alexander Bublik and Taylor Fritz. 

Medvedev won in straight sets against unseeded American Frances Tiafoe, hitting 24 winners.

Second seed Stefanos Tsitsipas won in straight sets against 24th seed Lorenzo Sonego, although the second went to a tie-break which the Greek dominated.

World number eight Andrey Rublev got past Marin Cilic in straight sets to book his last-eight spot.

Fifth seed Diego Schwartzman was the major casualty on Tuesday, losing to unseeded American Sebastian Korda in three sets. Seeds Josh Isner, Milos Raonic and Taylor Fritz also exited.

TOP SEED EASES INTO LAST EIGHT

World number two Medvedev was too good for Tiafoe in a 6-4 6-3 victory.

Medvedev improved his 2021 record to 17-2, sending down 11 aces with a dominant first-serve display while taking three of his four break points.

The 2021 Australian Open runner-up will meet seventh seed Roberto Bautista Agut in his maiden Miami Open quarter-finals appearance.

"It was definitely a tough match," the Russian said in his post-match on-court interview. "I am just looking forward to tomorrow. Roberto is a hell of a player.

"I feel like sometimes, when I have practised with him and played against him, that his ranking should be higher. There are reasons why it is not and I am going to try to do something with it tomorrow."

STEFANOS SIZZLES PAST SONEGO

Tsitsipas kept up his good form after making last month's Australian Open semi-finals, by booking his first Miami Open quarter-final appearance.

The Greek world number five defeated Sonego 6-2 7-6 (7-2) with a clinical performance to keep alive his dream of a maiden ATP Masters title.

Tsitsipas won in just over an hour and a half, proving too good on serve, having not offered up one break point and winning 89 per cent of first-serve points.

He was also too good with his return for the Italian, winning 35 per cent of the points on Sonego's serve.

The Greek will take on Polish 26th seed Hubert Hurkacz in the last eight, after he knocked out 12th seed Raonic 4-6 6-3 7-6 (7-4).

FIFTH SEED TOPPLED BY KORDA

World number nine Schwartzman was knocked out in three sets by Korda 6-3 4-6 7-5 as he continues his super run.

Florida resident Korda, 20, reached his maiden ATP 1000 quarter-final, showing fight after the Argentinian raised his game in the second set, winning after an early break in the last.

Rublev made light work of former US Open champion Marin Cilic, triumphing 6-4 6-4.

Bautista Agut got past 18th seed Isner 6-3 4-6 7-6 (9-7), while Jannik Sinner defeated Alexander Zverev's conqueror Emil Ruusuvuori 6-3 6-2.

Alexander Bublik, seeded 32nd, sent down 23 aces as he beat Taylor Fritz 6-7 (5-7) 6-3 6-4.

Dimitrov had been a set and a double break down against the Russian star on Wednesday, before launching a remarkable rally for his first win over a top-two opponent since 2016.

Meanwhile, second seed Stefanos Tsitsipas and third seed Alexander Zverev both won to secure their spots in the last eight.

MEDVEDEV SHOCKED IN THE DESERT

Dimitrov roared back to triumph 4-6 6-4 6-3 over Medvedev, who had won 18 of his past 19 matches on North American soil.

Bulgarian star Dimitrov trailed 4-1 in the second set after dropping the opener before stunning the first-time grand slam champion midweek.

"I just felt something at 1-4 and I calmed myself down and started to take better decisions and started to control the pace of the game, which I really believed helped me," Dimitrov – the 23rd seed – said. "In the end it was just very solid and smart play."

Dimitrov finished the match with 25 winners, while he was also excellent at the net, helping him claim his first quarter-final appearance at an ATP Masters 1000 event this season.

Medvedev sent down 5-1 aces but only managed a 54 per cent first-serve percentage, while he also faced 10 break points across the match. Dimitrov won five games in a row to claim the second set.

"I don't remember myself losing three service games, even four service games ever, I guess, on hard courts," Medvedev said.

"That shows how slow this court is and the conditions, more like clay, I would say, which I don't like, because to lose serve four times is just unacceptable."

Dimitrov will face eighth seed Hubert Hurkacz in the quarter-finals after he got past Australian Open semi-finalist Aslan Karatsev 6-1 6-3.

Medvedev added: "Grigor played [the] second part of the match better than anybody did against me [at the] US Open that I won. Playing this level, I don't see him losing to anybody, but let's see the result."

ZVEREV MAKES STATEMENT WITH MONFILS WIN

Olympic Games gold medallist Zverev bulldozed his way past 14th seed Gael Monfils 6-1-6-3 en route to the last eight.

German star Zverev claimed his 20th win from his last 21 matches, needing just over an hour to dispatch Monfils.

Zverev claimed 19 of 25 points at the net, hitting 19 winners including 11 with his forehand, while converting four of eight break points.

"I felt well on the court today. Gael is someone I haven't beaten before, so I knew had to play my best tennis and I definitely was not far away," Zverev said during his on-court interview.

Zverev will take on American 31st seed Taylor Fritz, who defeated 10th seed Jannik Sinner 6-4 6-3.

TSITSIPAS OUTLASTS DE MINAUR

French Open runner-up Tsitsipas saw off a tough challenge from Australian Alex de Minaur to secure his spot in the quarter-finals 6-7 (3-7) 7-6 (7-3) 6-2.

Tsitsipas fought back from a set down to win against the 22nd seed, triumphing in two hours, 43 minutes.

Greek star Tsitsipas showed grit to outlast the tiring De Minaur and will face 29th seed Nikoloz Basilashvili after he knocked off fellow seed Karen Khachanov 6-4 7-6 (8-6).

"That was incredible the way I just stayed in the match," Tsitsipas said. "I had to go through so many difficulties in order to find a solution and I executed towards the end of the match."

There were further top-10 casualties, with sixth seed Casper Ruud also bowing out 6-3 6-3 to 11th seed Diego Schwartzman, who will meet Cameron Norrie in the quarters.

The 37-year-old Frenchman has not played competitively since August last year due to injury but was eliminated by Thompson 6-3 6-1 in one hour and five minutes.

The Australian was ruthless, converting four of six break points generated, while he did not offer up any to Monfils.

Monfils was rusty, committing 17 unforced errors to Thompson's five, but the veteran hit 14 winners.

Thompson's victory earns him a second-round meeting with second seed Stefanos Tsitsipas.

Brandon Nakashima won the battle of the Americans, getting past John Isner 7-6 (9-7) 6-3 in one hour and 39 minutes. Nakashima progresses to face fifth seed Daniil Medvedev.

China's Wu Yibing produced some thrilling tennis, including an astonishing volley, in his 6-7 (6-8) 6-0 7-6 (7-3) victory over Jaume Munar.

World number 38 Diego Schwartzman won 6-1 6-2 over fellow Argentinian Federico Coria, while 47th-ranked Jiri Lehecka got past Arthur Rinderknech 7-6 (7-4) 7-5.

Australia's Jason Kubler toppled Lorenzo Sonego 6-4 7-6 (7-4) in almost two hours, while 42nd-ranked Bernabe Zapata Miralles was beaten 6-2 7-6 (8-6) by Ugo Humbert.

Finland's Emil Ruusovuori triumphed with Constant Lestienne retiring down 6-4 4-1 and world number 46 Alexander Bublik was a shock casualty, going down 6-4 6-4 to Wu Ting-Lin.

Bublik and Murray have now beaten each other two times apiece this year after the third seed won 7-5 6-4 in Newport.

The Kazakh overpowered the three-time grand slam champion to move into the last four, winning 80 per cent of his first-serve points and breaking three times.

Murray hit back straight after being broken at the start of the second set, but the former world one trailed 4-3 after failing to hold for a third time and Bublik did not give him another look-in.

Bublik will do battle with Jason Kubler for a place in the final after he defeated fellow Australian James Duckworth 7-5 7-6 (7-3).

Sebastian Baez ended Thiem's encouraging run to the quarter-finals with a 6-2 6-7 (5-7) 6-4 win in Bastad.

Thiem, who has endured an injury nightmare, won his first match 14 months by beating Emil Ruusuvuori in the first round and followed that up by getting the better of Roberto Bautista Agut, but the former US Open champion will go no further.

Argentinian Baez will now come up against Andrey Rublev after the second seed from Russia saw off Laslo Djere 7-5 6-4.

Pablo Carreno Busta blew Diego Schwartzman away in a 6-1 6-0 thrashing, while Francisco Cerundolo got past Aslan Karatsev in straight sets.

Murray – a three-time grand slam champion – defeated Kudla 6-3 6-2 in just over an hour, winning an outstanding 28 of 31 (90 per cent) first-serve points on Tuesday.

The 34-year-old Murray was also on top on return, converting three of four break-point opportunities against Kudla, to complete a comprehensive display.

Murray – currently ranked 116th in the world – will face second seed Ruud next at the ATP 250 tournament.

Elsewhere, Grigor Dimitrov was made to work for his 6-3 1-6 7-5 victory over Hungarian Marton Fucsovics.

Former world number three Dimitrov triumphed in two hours, seven minutes, confirming a spot in the second round, where he will face US Open semi-finalist Felix Auger-Aliassime.

Diego Schwartzman – the sixth seed – progressed with a 6-2 6-3 win over Italian qualifier Federico Gaio.

Young American Sebastian Korda beat Tommy Paul 6-3 5-7 6-1 in more than two hours, while ninth seed Lorenzo Sonego, Cameron Norrie and Lloyd Harris were also victorious.

Two days on from beating Frances Tiafoe in a three-set epic, Murray fell to a 6-4 7-6 (8-6) loss to the second-seeded Argentine in Antwerp.

The three-time grand slam winner, who in January 2019 underwent hip resurfacing surgery, was 4-1 up in the first set but was reeled back in and lost out in a hard-fought contest.

Following the defeat, a frustrated Murray said: "I didn't make as many good decisions as I would have liked in the second set dealing with adversity.

"Mentally I was poor, and my attitude was poor on the court."

Murray is still slated to play in Austria and Stockholm before the season is out, while he could also enter the Paris Masters either via a wildcard entry or going through the qualifiers.

"There'll be a decision on the final Paris wildcard on Monday, but I might even play the qualis there," Murray added. 

"Sport is a results business. Play well or poorly doesn't really matter if you lose matches. You need to be winning. 

"That's what I want in the last few tournaments. They are really strong tournaments and there are no guarantees the results will come, but I want to win more matches."

Murray defeated the veteran Frenchman 6-4 6-4 on a rainy opening day in Cincinnati, capitalising on a strong service game to advance. 

Murray had 14 aces to just two double faults and won 81 per cent of points on his first serve while saving four of the five break points he faced. 

A two-time champion at the ATP 1000 event, he will face the winner of Tuesday's match between Alejandro Davidovich Fokina and ninth seed Hubert Hurkacz in the second round. 

Two players who shared a birthday Monday also prevailed on their big day. 

On the day he turned 20, 11th seed Jannik Sinner defeated Federico Delbonis 6-2 7-5, while 10th seed Diego Schwartzman had to work a bit harder on his 28th birthday to down Daneil Evans 6-2 4-6 6-3. 

Elsewhere, 12th seed Felix Auger-Aliassime beat Marton Fucsovics 7-6 (7-0) 6-3, while 14th seed Alex de Minaur rallied to down Filip Krajinovic 0-6 6-4 6-4. 

Fifteenth seed David Goffin fell 6-3 6-3 to Guido Pella in the only seeded upset of the day. 

Other winners Monday included Karen Khachanov, Fabio Fognini, Lloyd Harris, Dominik Koepfer, Benoit Paire, Albert Ramos Vinolas and Mackenzie McDonald. 

Among those set to play their opening matches Tuesday are third seed Alexander Zverev, who will face Harris, and sixth seed Denis Shapovalov, who plays Paire. 

The three-time grand slam champion was largely in control against his Austrian opponent, hitting nine aces and saving all three break points against his serve, while Thiem could only save one of the three he faced as Murray won 6-3 6-4.

He will now play 14th seed Denis Shapovalov after the Canadian beat Ugo Humbert 7-6 (7-1) 6-3.

The winner of that contest will have a last-16 meeting against the victor of Novak Djokovic and Gael Monfils after the latter eased into the round of 32 to set up a clash with the Serbian.

Monfils defeated wildcard Carlos Gimeno Valero 6-3 6-0 in less than an hour, while Alejandro Davidovich Fokina also advanced with a 7-5 6-3 win against Lloyd Harris.

Dusan Lajovic set up a second-round match against fifth seed Casper Ruud, who defeated Borna Coric 6-3 4-6 6-4, and ninth seed Cameron Norrie will go up against John Isner, the Briton having overcome Soonwoo Kwon 7-5 7-5.

An interesting tie awaits the much-talked about Carlos Alcaraz after Nikoloz Basilashvili beat Fabio Fognini 7-5 6-4, with the Georgian to face the number seven seeded teenager next.

Jannik Sinner, the 10th seed, scraped through a hard-fought encounter against American Tommy Paul 6-7 (4-7) 7-6 (7-4) 6-3, and will play Alex de Minaur next after the Australian beat Pedro Martinez 7-6 (7-2) 1-6 6-3.

Diego Schwartzman will take on Grigor Dimitrov in the second round. The Argentine 13th seed beat Benoit Paire 6-2 6-7 (5-7) 6-1, while Dimitrov overcame Maxime Cressy 6-2 7-6 (7-4).

World number 20 Musetti is still just 20 years old, making him the third-youngest player inside the top-40. The only younger players are 19-year-olds Carlos Alcaraz (world number two) and Holger Rune (world number nine).

The talented Italian has two ATP Tour titles to his name, but none outside of Europe, and he will hope to change that after he advanced to the quarter-finals in Buenos Aires.

Musetti will play Peru's Juan Pablo Varillas next after he prevailed 6-4 6-4 against former world number three Dominic Thiem.

Fifth seed Francisco Cerundolo did his part to set up an all-Argentine quarter-final clash after dominating Jaume Munar 6-2 6-1, but compatriot Diego Schwartzman could not hold up his end of the deal, falling 6-1 6-3 to Spain's Bernabe Zapata Miralles.

Meanwhile, world number seven Taylor Fritz made a winning start to his Delray Beach Open campaign, defeating Ecuador's Emilio Gomez 6-4 6-3.

Fritz will play France's Adrian Mannarino in the quarter-final after the 34-year-old veteran eliminated 24-year-old American J.J. Wolf 7-5 6-2.

Second seed Tommy Paul was too strong for Denis Kudla in a 6-3 6-4 triumph, and he will play Radu Albot for a place in the semi-final after the Romanian emerged the 6-4 6-4 victor against Australia's Aleksandar Vukic.

Top seed Nadal secured an opening-set bagel in just 30 minutes, but Nishikori hit back to force a decider before the 20-time grand slam champion prevailed 6-0 2-6 6-2.

Nishikori hit only three winners as he was blown away in the first set, but broke twice in the second to ensure Nadal was taken to three sets in back-to-back matches for the first time in this tournament – having overcome Ilya Ivashka in the second round.

The world number three saved three break points from 0-40 down in the final set and Nishikori saw another two come and go, with a more clinical Nadal breaking twice to advance.

Nadal will now face unseeded Brit Cameron Norrie, who also won the first set 6-0 and was 5-3 down to David Goffin in the second when the Belgian retired due to a leg injury.

Newly-crowned Monte Carlo Masters champion Tsitsipas defeated Alex de Minaur 7-5 6-3, stretching his straight-sets winning streak to seven matches.

Next up for the second seed is a meeting with Felix Auger-Aliassime, who beat fellow Canadian Denis Shapovalov 6-2 6-3, while Jannik Sinner beat Roberto Bautista Agut 7-6 (11-9) 6-2.

Andrey Rublev, Diego Schwartzman and Pablo Carreno Busta also made it through.

Two seeds fell in the Serbia Open, with Federico Delbonis taking out Dusan Lajovic 6-3 2-6 6-4 and Taro Daniel defeating John Millman 3-6 6-2 6-3.

Gianluca Mager moved into the quarter-finals at the expense of Alexei Popyrin and Aslan Karatsev battled past Aljaz Bedene 6-3 4-6 7-6 (7-5) in Belgrade.

Competing in his first tournament since February, Nadal has looked in fine form in Rome and followed up Wednesday's impressive 6-1 6-1 dismantling of Pablo Carreno Busta with another encouraging display, beating Lajovic 6-1 6-3.

Lajovic did show some fight during the early exchanges, responding well to a break of serve by breaking back – and to love.

But a marathon game, which included six instances of deuce, followed and Nadal prevailed to go 3-1 up, before going on to lose just four more points when closing out the opening set.

Lajovic looked set to lose with a whimper when successive breaks gave Nadal a 4-0 lead in the second, and although the former responded by winning three games on the bounce, he had given himself too much to do and the Spaniard cruised to victory.

Nadal was a class above for much of the contest, cleverly pulling the Serbian this way and that, and the world number two does not think he could be doing much better.

"I played I think a very positive level of tennis. Of course it needs to keep improving," Nadal said. "I need to keep working on a couple of things that are not coming automatically, but I can't ask for more.

"[It was] another great evening for me against another good opponent. Can't complain at all. Much better [than] what I expected.

"The first set was 6-1, but a super-tough beginning of the match. A lot of good points. I'm very happy, it's an important victory for me after such a long time. To start the tournament with these two victories is great news."

Earlier in the day, world number one Djokovic felt he was "pushed to the limit" by fellow Serbian Filip Krajinovic as he won 7-6 (9-7) 6-3 to reach the last eight in the tournament for a 14th successive year.

It was the first time in more than a decade that the two friends had met on the court and Djokovic was made to work particularly hard, saving five of six break points over the course of the contest and fighting back from 4-1 down in the tie-break before ultimately outlasting his compatriot.

Djokovic's next opponent will be Dominik Koepfer, who dealt with Lorenzo Musetti in relatively comfortable fashion, winning 6-4 6-0.

Fourth seed Matteo Berrettini was pushed all the way by fellow Italian Stefano Travaglia to secure his spot in the next round, coming through a tense 7-6 (7-5) 7-6 (7-1) to set up a meeting with Casper Ruud, who beat Marin Cilic 6-2 7-6 (8-6).

Eighth seed Diego Schwartzman was given a run for his money by Poland's Hubert Hurkacz, but the Argentinian came from behind to prevail 3-6 6-2 6-4.

He will be up next for Nadal, while the other quarter-final will be contested between Grigor Dimitrov and Denis Shapovalov, both of whom came through three-setters on Friday.

World number two Nadal is bidding to win the ATP Masters 1000 tournament for the first time and fought from a set down to triumph 4-6 7-5 6-1 and improve his record against his fellow Spaniard to 7-0.

With Schwartzman having lost his quarter-final against Daniil Medvedev 6-3 6-1 earlier on Friday, Carreno Busta needed to win back-to-back titles in Paris and Sofia to stop the Argentinian taking the last remaining qualifying spot for the season-ending tournament.

He appeared to have a significant chance of keeping his hopes alive when he engineered three break points at the start of the second set, but 20-time grand slam champion Nadal held firm and forced his way into a final-four meeting with Alexander Zverev or Stan Wawrinka.

Nadal came under early pressure on his serve and Carreno Busta took his second chance to break, his impressive groundstrokes proving difficult for his opponent to cope with.

Back-to-back brilliant backhands put him on the brink of going a set and a break up in the first game of the second, but Nadal dug in to hold and began to step through the gears.

Carreno Busta showed impressive resilience to keep the contest on serve in games two and eight, before a wicked forehand down the line forced the match to a decider.

The ninth seed was broken to love in game four of the decider and won just two more points as Nadal surged to victory.

In the other semi-final Medvedev will take on Milos Raonic after the Russian took just 63 minutes to dispatch of Schwartzman.

Things were not as easy for Raonic, who staved off two match points and sent down 25 aces as he overcame Ugo Humbert 6-3 3-6 7-6 (9-7).

The Canadian saved all three of the break points he faced in the third set – and five out of six overall – and closed out the victory with a final ace.

Nadal's fellow Spaniard Feliciano Lopez went close to a major upset as the veteran pushed him all the way, but Nadal came through 4-6 7-6 (7-5) 6-4.

After sweeping to French Open glory last month without dropping a set, Wednesday's match marked Nadal's return to action and it took him two hours and 30 minutes to get the job done.

He sits fourth on the list of players with the most wins in the Open Era, behind Jimmy Connors, Roger Federer and Ivan Lendl.

There were also victories for Alexander Zverev, Diego Schwartzman, Milos Raonic and Alex de Minaur. while Daniil Medvedev went through after opponent Kevin Anderson retired due to injury during a first-set tie-break.

Away from clay, Nadal looks vulnerable in Paris

Nadal was imperious at Roland Garros, roaring through the draw on the way to his 13th French Open title.

Across town, at the Bercy Arena, it has been a different story throughout Nadal's career.

The indoor hard-court event is one he has never won and has often skipped, with this just his eighth appearances in the main draw, and this was almost a brief visit as Lopez made a storming start.

Lopez managed what nobody could at Roland Garros by swiping that first set after a break of serve in the opening game of the match, but 20-time grand slam winner Nadal stepped up his game to reach the last-16 stage and chalk up a landmark win.

The 39-year-old Lopez saved five break points in the second set to earn a tie-break, only for Nadal to edge it and then break serve for the first time at the outset of the decider.

With his hard-fought success, Nadal, 34, extended his head-to-head winning record to 10-4 against Lopez, with their rivalry having begun on an indoor carpet court in Basel back in 2003.

Likely challengers come through

German fourth seed Zverev swept to a 6-2 6-2 win against Serbian Miomir Kecmanovic, while Schwartzman swatted away Richard Gasquet, landing a 7-5 6-3 win over the Frenchman.

There was more disappointment for French hopes as Pierre-Hugues Herbert lost 6-4 6-4 to Canadian Raonic, and Russian Medvedev was embroiled in a battle with Anderson when the South African pulled out of the contest.

Sonego's early exit

Lorenzo Sonego arrived in Paris off the back of a successful week in Vienna, where he knocked out Novak Djokovic in the quarter-finals and went on to finish runner-up to Andrey Rublev.

This week will linger less in the memory for the Italian, who went down 6-3 7-5 to De Minaur.

Nadal, 34, has won the competition more times than anyone else in its history and looked in good shape as he returned to the court for the first time since losing to Stefano Tsitsipas in the Australian Open quarter-finals on February 17.

He needed just 81 minutes to get past the Argentinian qualifier 6-1 6-2 as he improved his record in the tournament to 72-5, breaking Delbonis' serve five times and only dropping his own once.

He is not getting carried away, however, with Grigor Dimitrov likely to provide a sterner test in the next round after beating Jeremy Chardy 7-6 (7-3) 6-4.

"It was solid match, I think. Of course, a very positive result. He's a good player on clay. [It was a] positive start for me," Nadal said in his post-match interview.

"I think I just really played a solid match. Nothing unbelievable, but nothing wrong. Just a solid match, a positive start. I think I did what I had to do."

On Dimitrov, Nadal added: "We've had some great matches. In Melbourne, of course... we played another great match in Beijing, another one in Shanghai. He's a good friend, a good guy, and a great player. It's going to be a tough test in my second round.

"It's going to be his third. I need to be ready for it. I hope to be ready for it. I am just excited to play a tough match very early in the tournament."

A little earlier in the day, world number one Djokovic was in a similarly unforgiving mood as he overcame the potentially tricky obstacle of Jannik Sinner, the Serbian and two-time Monte Carlo champion winning 6-4 6-2.

Like Nadal, Djokovic was back in action for the first time since the Australian Open – which he won – and appeared fresh as he gave the promising young Italian something of a lesson in game management, reaching 10 matches unbeaten at the start of a season for the sixth time.

"It feels great [to be back and] also playing in Monaco, where I reside," Djokovic said. "I have used this club as a training base for almost 15 years, so it feels like playing at home."

Despite the rather commanding nature of his win, Djokovic was keen to pay tribute to the 19-year-old Sinner, adding: "It was a very good encounter. I thought it was a great first match [and] a big challenge for me. Jannik is in form. He played the final [in] Miami and has been playing well. I just hung in there today and managed to find the right shots and the right game at the right time.

"He has got a lot of talent and he has proven that he is the future of our sport. Actually, he is already the present of our sport. He played a final [in an] ATP Masters 1000 [tournament] already. He is making big strides in professional tennis."

Dan Evans awaits Djokovic after an impressive 6-4 6-1 win over Miami champion Hubert Hurkacz, while Alexander Zverez and Andrey Rublev – the fifth and sixth seeds – moved into the next round with respective straight-set victories over Lorenzo Sonego and Salvatore Caruso.

There were mixed fortunes for the other two top-10 seeds in action on Wednesday, as Pablo Carreno-Busta defeated Karen Khachanov 6-2 6-3, but Diego Schwartzman was sent packing by Casper Ruud, the Norwegian winning 6-3 6-3.