Mikel Arteta suggested he would be "suspended for six months" if he gave his honest assessment of key refereeing decisions made during Arsenal's 3-0 north London derby defeat to Tottenham.

Arsenal went into what many considered as the most important north London derby in Premier League history knowing victory would secure Champions League football for next season.

But they were blown away by Spurs at the Tottenham Hotspur Stadium, with Rob Holding's 33rd-minute sending off for two bookings playing a big role – though the hosts were already 1-0 up thanks to a Harry Kane penalty.

Kane got Spurs' second shortly after Holding's dismissal and Son Heung-min put the game beyond the Gunners early in the second half, as Antonio Conte's men moved to within a point of Arsenal heading into the final two matchdays of the season.

Should Arsenal ultimately miss out on Champions League football again, many will point to this defeat as a pivotal moment, and Arteta seemingly laid the responsibility at the feet of the officials.

When asked for his "thoughts" on the game, Arteta told Sky Sports: "Well, if I say what I think, I'm suspended [for] six months, so I cannot say.

"I'm allowed to give my interpretation of what happened in the game, but I don't know how to lie so I prefer not to say what I think."

But it was unclear precisely which decision Arteta felt aggrieved by, as Holding was arguably lucky not to have been already sent off before his brutal barge on Son, which in itself could have potentially drawn a straight red.

That was his fourth foul of the game, more than he has ever committed in a single Premier League match despite playing just 33 minutes.

Similarly, the decision to penalise Cedric Soares for a shove on Son in the area appeared a clear-cut one by referee Paul Tierney.

Arteta initially refused to delve much deeper, as he reiterated the belief he would be banned if he was honest, but he did eventually call out the officials.

"You can ask the referee to come in front of the camera and explain his decisions," he said. "It's a shame because such a beautiful game was destroyed today."

Arsenal have two more matches to secure fourth – they face Newcastle United and Everton in their last games of the season.

Rafael Nadal suffered his earliest Internazionali d'Italia exit since 2008 at the hands of Denis Shapovalov on Thursday, but Novak Djokovic advanced to the quarter-finals. 

'King of Clay' Nadal fell to a 1-6 7-5 6-2 defeat to Shapovalov in the third round in Rome, with the Canadian surging to victory after winning 12 straight points from 2-2 in the deciding set. 

The legendary Spaniard stormed through the first set thanks to a series of brilliant returns, but his opponent dominated at the net in the second to take the match the distance. 

Shapovalov then flipped the narrative on its head by winning 14 of a possible 22 return points to set up a quarter-final meeting with Casper Ruud, who beat Jenson Brooksby 6-3 6-4. 

Djokovic is one win away from retaining his status as world number one after taking just 75 minutes to see off three-time grand slam winner Stan Wawrinka 6-2 6-2. 

After a lengthy spell out injured, Wawrinka ended a 15-month wait for an ATP Tour victory at Foro Italico before the Serbian brought his run to an end. 

"It is great to see Stan back and winning. He won two tough matches. You can see he is still not physically where he wants to be. But, nevertheless, he is Stan Wawrinka and he can hurt you if you give him time," Djokovic said. 

"I managed to do well from the beginning. I really moved him around the court and held my serve comfortably except for that loss of my serve in the second set." 

Felix Auger-Aliassime stands between Djokovic and the number one spot after overcoming lucky loser Marcos Giron 6-3 6-2. 

In the other half of the draw, Stefanos Tsitsipas and Jannik Sinner will play out an entertaining quarter-final after they beat Karen Khachano and Filip Krajinovic respectively. 

Alexander Zverev, the defeated finalist in Madrid last week, beat Alex De Minaur 6-3 7-6 (7-5) and will battle Cristian Garin for a place in the final four.

Karim Benzema moved level with Raul as Real Madrid's second-highest all-time top goalscorer and Vinicius Junior scored a hat-trick as the LaLiga champions relegated Levante with a 6-0 hammering.

Ferland Mendy got Carlo Ancelotti's side, who were crowned champions a fortnight ago, on their way early on, before Benzema joined Madrid icon Raul on 323 goals soon after.

Rodrygo and Vinicius added further goals before the interval, with the latter completing his treble in the second half at the Santiago Bernabeu on Thursday.

While the rout restored Madrid's 12-point advantage over Barcelona at the summit, it condemned Levante drop with two games to play.

Any hopes Levante had of causing an upset were dispelled in the 13th minute when Mendy powered into the penalty area and slotted past Daniel Cardenas.

Federico Valverde then steered a volley against the post, before Benzema doubled his side's advantage with a close-range header from Vinicius' cross after 19 minutes.

Rodrygo slid home Luka Modric's cross to make it three in the 34th minute, while Cardenas twice pushed Valverde drives onto the crossbar as Madrid dominated.

They made it four in the 45th minute, when Vinicius collected Modric's pass and curled past Cardenas from a tight angle.

Cardenas pawed away Modric's whipped effort and Vinicius saw an effort ruled out for offside after the interval. 

The Brazil international was not to be denied in the 68th minute, though, tapping into an empty net after Benzema had rounded Cardenas.

He had his hat-trick seven minutes from full-time courtesy of a cool finish from 10 yards out after breaking through Levante's dispirited backline. 

Mikel Arteta and Arsenal now face a thorough examination of their mentality and focus after Thursday's morale-sapping 3-0 north London derby defeat blew the race for fourth wide open.

While the importance of Champions League qualification might feel exaggerated to some given the financial muscle of practically every Premier League club, regardless of finishing in the top four or not, the end of 2021-22 will undoubtedly have significant implications for both clubs.

A top-four finish would be Arsenal's best Premier League season in six years and simultaneously the first time since the same season that they'd finished above their bitter rivals.

Champions League qualification would also be vindication of the faith placed in Arteta and a clear sign of genuine progress since he replaced Unai Emery.

For Spurs, on the other hand, it's difficult to look at these final 10 days of the season being anything other than a sliding-doors moment.

Failure to return to European football's top table would plausibly see Antonio Conte call it quits, whereas the possibilities could be endless under him with the extra cash, exposure and lure provided by the Champions League, particularly when you consider the transformational effect he's already had in north London and elsewhere previously.

With those points in mind, it was no surprise to see Thursday's contest – the first with fans present at the Tottenham Hotspur Stadium – labelled the most important north London derby in Premier League history, and it's fair to say the hosts handled the occasion far better than the Gunners.

Perhaps that wasn't actually as shocking as it initially felt during the match.

The turning point came with just 33 minutes on the clock. While Tottenham were already ahead thanks to a Harry Kane penalty, it was just past the half-hour mark when Rob Holding's pushed his luck once too often.

Having already been booked – frankly, he could have been carded several times by this point – Holding cynically blocked off the relentless Son Heung-min with a combination of shoulder and elbow, deservedly earning himself a second yellow and subsequent red card.

It had been coming. Holding's early duels with Son had the South Korean showing signs of frustration – not because he couldn't get the better of his opponent, but because he was getting the better of him. He just kept getting fouled by the Arsenal defender.

Holding's wry smile when walking away from an angry Son after a tangle that wouldn't have looked out of place on a Judo mat belied a degree of arrogance and misplaced confidence.

It was ill-judged to say the least.

But of course, this is by no means the first time indiscipline's been seen as the scourge of Arsenal. Since Arteta's appointment, the Gunners have been shown five more red cards (13 in total) in the Premier League than any other team.

Granted, they are the youngest team in the Premier League, so perhaps a hint of indiscipline is to be expected as a consequence of inexperience – but that argument can't really be applied to 26-year-old Holding.

Arsenal had actually started the match quite well. Their pressing intensity was excellent, so much so that a Spurs passage of play consisting exclusively of passes between the defence and Hugo Lloris drew significant jeers of derision and frustration from the home crowd.

But Spurs identified they could find joy by playing direct, which was exactly how the opener arrived, with Cedric Soares – no, not Holding this time! – the one guilty of barging Son over at the back post as he looked to reach a deep delivery.

Just four minutes after Holding's red card, Kane – who had endured a career-worst derby drought of two matches prior to Thursday – exploited Eddie Nketiah's lack of awareness to stoop in at the back post to head home his second goal of the game, extending his all-time record as this fixture's top scorer.

Conte was a figure of calm after the first goal, but this time he wore his near-trademark terrifying jubilation with pride, presumably aware only a miracle would save Arsenal now.

The sparkling Son made sure any Arsenal hopes were thoroughly extinguished less than two minutes after the restart, pouncing on a loose ball in the area before steering beyond Aaron Ramsdale with the kind of expertise we've come to expect from a player only outscored by Mohamed Salah in the Premier League this season.

Arteta can console himself with the fact Arsenal remain fourth heading into their final two games of the season. Had you given him the option of being in that situation back in August, he'd have snapped your hand off.

But Thursday's ultimately crushing defeat once again raised questions of the Gunners' mentality and discipline, and their squad is becoming more depleted by the game. It's hardly an ideal combination when the pressure is on – and boy is it on now.

Tottenham – whose kind run-in sees them face Norwich City and Burnley – still need either Newcastle United or Everton to do them a favour at the very least.

But Thursday was evidence of Spurs keeping their cool when it matters. Arsenal didn't, and there's nothing to suggest they're too good to capitulate.

Tottenham secured a huge victory in the race for Champions League qualification by winning 3-0 against Arsenal, who played an hour of the north London derby with 10 men. 

A win for Arsenal would have been enough for them to clinch a top-four finish in the Premier League for the first time since 2016, but they are now just one point clear of Spurs with two games remaining. 

Harry Kane scored the opener from the penalty spot after Cedric Soares' foul on Son Heung-min and it was a coming together with the South Korean that resulted in Rob Holding being shown a second yellow card in the 33rd minute. 

Kane doubled his tally before half-time and Son put the result beyond doubt early in the second period, putting Antonio Conte's men firmly in contention for a Champions League spot. 

Tottenham were awarded a penalty in the 22nd minute when Cedric shoved Son over in the box and Kane showed great composure to send his spot-kick into the bottom-right corner.  

Holding was given his marching orders after catching Son in the head with his arm and Spurs doubled their advantage just four minutes later.  

Son's corner was helped on towards the back post by Rodrigo Bentancur, with Kane stooping to nod into the back of the net from close range.  

Things got worse for Arsenal just two minutes after the restart, with Son dinking the ball home through a crowd of bodies after Gabriel Magalhaes' tackle on Kane. 

Aaron Ramsdale made two saves in quick succession to deny Emerson Royal and Kane, while Son was unable to turn Ryan Sessegnon's pass on target despite being one-on-one with the keeper. 

Gabriel hobbled off late on with a hamstring injury for the Gunners, who were left to mull over a defeat that put a dent in their hopes of a return to the Champions League.

What does it mean? Gunners see red 

Arsenal were completely undone after Holding's dismissal, which was their 13th red card in the Premier League since Mikel Arteta's first game in charge in December 2019 – that is five more than any other team in the same timeframe. 

They were unable to keep things tight and consequently fell to a third straight away loss to Spurs in the league for the first time since August 1961.  

The Gunners must regroup ahead of a trip to Newcastle United and a clash with Everton, with Spurs still to face Burnley and Norwich City.

Another Kane-ing for Arsenal 

With his first-half double, Kane took his haul of top-flight goals against Arsenal to 13. The only team he has scored more against in the competition are Leicester City (17). Kane has now been involved in 52 goals in 69 London derby appearances in the Premier League, two behind Thierry Henry's record. 

No Holding on for Gunners 

While they still had their full complement, Arsenal had a chance of getting back into the game at 1-0 down. However, Holding managed to commit four fouls – the most he has made in a single Premier League appearance – in the opening 33 minutes and his red card ruined their hopes. 

What's next?  

Spurs entertain Burnley on Sunday, meaning Arsenal could be outside the top four when they play away at Newcastle United on Monday 

Liverpool forward Mohamed Salah did not mince his words when defending his place as he declared he is the best player in the world in his position.

The Egypt international is on track to win the Premier League Golden Boot, while also boasting the highest assist tally in the top flight, being directly involved in 35 goals from his 34 appearances.

Salah was recently named the Football Writers' Association Player of the Year in England, and has a chance to make history with this Liverpool team as they have won the EFL Cup, and are still in the hunt for the Premier League title, FA Cup and Champions League.

Speaking to beIN SPORTS, Salah was adamant that there is no forward in world football scaling his heights.

"If you compare me with any player in my position, not only in my team but in the world, you will find that I am the best," he said.

"I always focus on my work and do my best, and my numbers are the best proof of my words.

"I like to always create a new challenge for me, to work in a different way and to make a difference, and that is my duty."

Ahead of Liverpool's Champions League final against Real Madrid – which is a rematch from the 2018 final, when the Spaniards won 3-1 – Salah called it "revenge time".

"Yeah – when we lost in the final, it was a sad day for all of us," he said. "But, yes, I think it's revenge time."

Sebastian Munoz made PGA Tour history by shooting his second 60 of the season at the AT&T Byron Nelson on Thursday. 

World number 73 Munoz became the first PGA Tour player with two rounds of 60 or better in the same season by going 12-under par at TPC Craig Ranch.  

It followed the Colombian's 10-under 60 in the opening round of the RSM Classic at Sea Island Resort last November. On that occasion he finished third. 

After bogeying the par-four eighth to slip to two under, Munoz gained six shots across the next four holes – eagles at nine and 12 for the second straight year sandwiching consecutive birdies. 

Munoz added birdies at 14, 16 and 17 before recovering from a wayward approach shot at the last by getting up and down for a further gain and a back nine of 28. 

Despite heading to the clubhouse with a comfortable lead, Munoz was disappointed not to have gone under 60 for the first time in his career. 

Asked what he was thinking while stood on the 18th fairway, he replied: "59. Yeah. I wanted to give myself a chance. 

"I think it was 250 [yards] to the pin into the wind. I kind of wanted to hit like a bullet, like a little draw. I knew if I want to hit it close it had to be a fady, soft-landed shot; I tried to do that. Overdid it and ended up with a 60, which is really good around here. 

"It's a great feeling whenever everything is clicking, hitting the tee shots, ball is coming out in the window that you imagined, you're reading good the putts well. When everything is going it's just stay out of the way and just kind of let it happen. 

"So that's what I did. I had a tough putt on 12 for eagle and like I was thinking like, it's okay if I don't make this one. Then it was like, I know I can make it, just kind of stay in it, trust what you're doing ... I made it. 

"Yeah, coming in it was a great stretch and [I'm] really happy." 

Arnaud Demare enjoyed another successful day at the Giro d'Italia as he registered his second stage victory of this year's race.

Demare pipped Caleb Ewan in a thrilling sprint finish to stage six on Thursday, just nudging the tip of his wheel ahead of the Lotto Soudal rider as they crossed the finish line in Scalea.

At the end of a relatively flat route, Mark Cavendish made a late push, but was unable to latch onto the front two at the end.

"It was a really calm stage and everybody had fresh legs. Yesterday it was a collective job and today we had everyone as well," said Groupama-FDJ rider Demare.

"At each roundabout we were perfectly placed. Around 500m, Jacopo [Guarnieri] did a great job and I got myself into the wheels. The sprint lasted about 100m and I managed to get there.

"I thought maybe it was me that was second until we saw the photo."

It was a frustrating day for Fernando Gaviria (UAE Team Emirates), meanwhile.

The Colombian had expressed frustration with his bike after stage five, saying "what a s*** bike", and this time he collided with Alberto Dainese and Cees Bol on the home stretch.

Gaviria was deemed to be at fault and relegated, so he has dropped from third to fifth in the points classification, losing 13 points.

There was little change in the general classification standings, with Juan Pedro Lopez keeping hold of the maglia rosa, though his lead was cut by a second.

DEMARE MAKING FRANCE PROUD

That was Demare's seventh stage win at the Giro d'Italia, meaning he has now won more stages in the Grand Tour event than any other French rider.

According to the Giro's official data, across the 13-second sprint, Demare averaged a remarkable 68.4 km/h speed, while maxing out at 1,410 watts of power.

STAGE RESULT  

1. Arnaud Demare (Groupama-FDJ) 5:02:33
2. Caleb Ewan (Lotto Soudal) same time  
3. Mark Cavendish (Quick-Step Alpha Vinyl Team) same time 
4. Biniam Girmay (Intermarche-Wanty-Gobert) same time
5. Giacomo Nizzolo (Israel-Premier Tech) same time

CLASSIFICATION STANDINGS   

General Classification  

1. Juan Pedro Lopez (Trek-Segafredo) 23:23:36
2. Lennard Kaemna (Bora-Hansgrohe) +0:38
3. Rein Taaramae (Intermarche-Wanty-Gobert) +0:58

Points Classification

1. Arnaud Demare (Groupama-FDJ) 147
2. Biniam Girmay (Intermarche-Wanty-Gobert) 94
3. Mark Cavendish (Quick-Step Alpha Vinyl Team) 78

King of the Mountains  

1. Lennard Kamna (Bora-Hansgrohe) 43
2. Mirco Maestri (EOLO-Kometa Cycling Team) 18  
3. Juan Pedro Lopez (Trek-Segafredo) 18

Former England captain Michael Atherton has praised the "bold and imaginative" appointment of Brendon McCullum by England.

McCullum was named England's new Test head coach on Thursday, replacing Chris Silverwood after his dismissal in the wake of the 4-0 Ashes defeat in Australia.

Rob Key decided to bring in separate Test and white-ball head coaches after he was appointed as managing director of England men's cricket last month and chose McCullum for the longer form of the game.

"I think it's a very bold and imaginative choice, and an inspiring choice from Rob Key," Atherton told Sky Sports.

"Giving Ben Stokes the captaincy was the obvious choice and so his first big decision was to give Brendon McCullum the Test job.

"A week or so ago I don't think that was on anybody's radars, so he's not made the obvious choice here, but I think it's a very bold choice."

McCullum captained New Zealand and has coached in limited overs cricket in the Caribbean and Indian Premier Leagues, but this is his first coaching job in Test cricket.

Atherton does not think that lack of experience is a problem, however.

"I don't think it's a concern. Some other people within the professional coaching environment may think so," the former Lancashire batsman said.

"His limited coaching experience has come in the IPL with the Kolkata Knight Riders and in the CPL with their sister team. But he did play 100 Tests, scored a Test match triple hundred and he was very significant in Test cricket in his own right.

"As captain, he really led New Zealand into a brave new era, from the moment he took over – in Cape Town 2013 – the very first innings New Zealand were bowled out for 45. It was a really low ebb and a very difficult transition from Ross Taylor.

"But after that, he led boldly and fearlessly, and transformed that New Zealand team to the point which he laid the foundations for Kane Williamson's team that became World Test champions and have been very significant players in ICC events. So as a captain and as a leader, he's got plenty of experience in Test cricket."

Atherton also believes the relationship between McCullum and new England skipper Ben Stokes should thrive given both have similar aggressive approaches to the game.

"He's a nice fit with Stokes, they both approach the game and play the game in a similar manner and they'll look to give very clear message, captain and coach, and show they're singing from the same hymn sheet to a team you now expect to be given a bit of freedom and licence to play," he said.

"Neither Stokes nor McCullum are shy characters when it comes to playing the game of cricket, they like to take the game on and play it aggressively.

"One assumes that McCullum as a coach is going to be very similar to McCullum as a player and captain."

Fabinho has been ruled out of Saturday's FA Cup final, but Liverpool manager Jurgen Klopp hopes the midfielder will return before the end of the season.

Brazil international Fabinho was forced off during the first half of Liverpool's 2-1 win over Aston Villa on Tuesday.

It was subsequently confirmed that the 28-year-old had sustained a muscle problem and Klopp has confirmed he will not feature against Chelsea at Wembley.

However, Klopp is confident that Fabinho will make his comeback in time to play against Real Madrid in the Champions League final on May 28.

"There's a good chance that he will be available for the Champions League final," Klopp told Liverpool's official website. "Not for the weekend."

Liverpool trail Manchester City by three points in the Premier League, with two games remaining. They face Southampton next week and host Wolves in the final fixture of the campaign.