Harry Maguire and Tyrell Malacia put through their own goal late on as Manchester United squandered a comfortable lead in a 2-2 draw against Sevilla in the first leg of their Europa League quarter-final tie.

Captain Maguire deflected into his own net in the 92nd minute, just eight minutes after Malacia had turned past David de Gea as Sevilla somehow found a way back at Old Trafford in the quarter-final first leg.

A Marcel Sabitzer first-half double appeared to have Erik ten Hag's hosts in complete control, only for the late drama to leave United reeling by full-time.

Jose Luis Mendilibar's side will boast home advantage in a week's time as they eye a seventh Europa League title since the 2006-07 season.

Sevilla president Jose Castro rallied his side ahead of their Europa League tie against Manchester United after the Spanish outfit landed in England for the first leg.

Castro reflected on Sevilla's rich history in the competition as reason for optimism despite the backdrop of a poor LaLiga campaign that sees them in 12th.

This Europa League track record includes six titles, with the most recent coming in 2020 after a semi-final 2-1 win over United.

Castro said: "We have the opportunity after a bad league season that we are doing. In Europe, we are in remarkable shape, and if we advance, it would be outstanding.

"We are the king of the competition, we are going to make it difficult, and the squad is aware, because for Sevilla, the Europa League is something else.

"[United] have the environment, the stadium, the squad, the budget, the clubs they have eliminated... but we are in our competition, and we are going to try to make it difficult, with the memories of going through as we have done on other occasions against this team."

In 2019-20, goals from Suso and Luuk de Jong saw Julen Lopetegui's side through, while Sevilla also eliminated United from the Champions League last 16 in 2017-18.

They are big underdogs this time, however, with Sevilla's domestic form contrasting with a top-four push in Manchester as Erik ten Hag continues to impose his vision on his United squad.

"We know the difficulty of the tie, which is complicated because they are a great team with a huge squad," Castro added.

"Sevilla never give up. We have this opportunity, and we are going to try to take advantage of it against a great team who are showing a lot.

"I see more options now because I see the team more compact and better in everything, but above all because we have players recovering.

"So many injuries in the same positions have affected us a lot, and now the coach has more options, something that could be decisive."

Indeed, this could be a key factor in at least the first leg. As Sevilla players return, Marcus Rashford and Luke Shaw are out for United.

Manchester United are at their best when Anthony Martial is in the team, according to manager Erik ten Hag.

Martial's career at Old Trafford since signing from Monaco in 2015 has been plagued by injuries, with the forward loaned out to Sevilla for the second half of last season where he scored just once in 12 appearances.

A strong pre-season meant this campaign started with optimism, though he has again been in and out of the line-up because of his fitness with Marcus Rashford's goals proving crucial in his absence.

With Rashford ruled out for several games with a muscle injury and January loan signing Wout Weghorst struggling in front of goal, Ten Hag needs Martial to start firing if United are to add more silverware to the EFL Cup they lifted in February, which ended a six-year trophy drought.

Ten Hag is confident the 27-year-old will be a big help over the rest of the season, though he will not rush the forward back to the team before he is ready despite him scoring off the bench in the 2-0 victory over Everton at the weekend.

"We don't have to force things," Ten Hag told reporters. "We are careful. The front line against Everton worked really well.

"When he [Martial] is in the team, we play our best football and we have our best results as a team. The time he needs for a goal is less. I defend him because I point to the stats and see how he contributes."

Martial's first start since January could come against his former side Sevilla in the Europa League on Thursday as United meet the six-time winners in the first leg of their quarter-final clash at Old Trafford.

Ten Hag believes Martial is ready to play from the off for the first time since returning from a hip injury, saying: "I think he is ready to start.

"But the front line did very well against Brentford and we picked the same against Everton. The advantage was we could bring Martial back slowly, giving him minutes, but I think already against Everton he was ready to start the game."

United could also be boosted by Christian Eriksen being available for the starting XI for the first time in over three months, after his strong start with the Red Devils was hampered by an ankle injury suffered against Reading in the FA Cup fourth round back in January.

Ten Hag believes the Denmark international's return will improve United's midfield, explaining: "I think the balance in the midfield was good with Casemiro, Eriksen and Bruno [Fernandes].

"Casemiro is the balance player, Eriksen can support him but also go to the final part of the game, can create chances with key passes.

"So yeah, a really important player and I think he had seven or eight assists in the league, which tells the story."

Marcus Rashford will miss Manchester United's next few games, the Premier League giants have confirmed.

Rashford suffered a muscle injury in United's 2-0 win against Everton on Saturday.

It was revealed on Wednesday that not only will the in-form forward be out for the Europa League quarter-final first leg against Sevilla on Thursday, but further games beyond that.

The 25-year-old has had a fine season for the Red Devils, scoring 28 goals in 47 outings, but will now miss the next "few games".

The club stated: "Marcus Rashford will be unavailable for Thursday’s UEFA Europa League quarter-final game against Sevilla because of a muscle injury.

"The forward was withdrawn in the 80th minute of Saturday’s 2-0 Premier League win over Everton at Old Trafford and immediately headed to the dressing room for treatment.

"Subsequent assessment of the injury suggested that Marcus will be unavailable for a few games, but is expected to be back for the season run-in."

United manager Erik ten Hag told the club's website he has confidence in other players stepping up to take on the goalscoring burden, with their next top scorers for the season after Rashford being Bruno Fernandes (10), Antony (7), Anthony Martial (7) and Fred (6).

"We have many more players across the squad who can score," he said. 

"I think we have players like Bruno, like Jadon Sancho, like Anthony Martial, like Scott McTominay, like Antony. We have enough players with the capabilities to score goals, definitely."

After they face Sevilla at Old Trafford, United visit Nottingham Forest in the Premier League on Sunday, before the return leg in Seville next Thursday.

France international Wissam Ben Yedder was sentenced to six months and one day in prison and fined €133,798 by a Spanish court on Tuesday for tax evasion.

The 32-year-old forward has had the prison sentence suspended, with the offence dating back to his time playing in Spain.

Ben Yedder spent three seasons at Sevilla, arriving from Toulouse in July 2016 and leaving to join Monaco in August 2019.

A ruling from the Provincial Court of Seville, dated March 9, was released and outlined how Ben Yedder failed to submit an income tax return on time and "consciously falsified" a self-assessment by not declaring interest he received as income in three accounts, also not declaring earnings from a sponsorship deal with Adidas.

The court said Ben Yedder paid €225,323.25 initially and later added a payment of €51,007.41 to cover for what was found to be the shortfall, plus interest, once it was discovered he should have paid €267,597.40.

The fine imposed on Ben Yedder, agreed by all parties, amounts to 50 per cent of the total described by the court as the "defrauded fee".

The prison element of the punishment has been suspended for two years, conditional on him not reoffending.

"In view of the imposed sentence of six months and one day in prison and the lack of a criminal record, together with the fact of having satisfied civil responsibilities, it is appropriate to agree to the suspension," the court stated.

Sevilla claim they have suffered "alarming" treatment at the hands of LaLiga referees this season and said the number of red cards shown should serve as an "urgent wake-up call" to league chiefs.

In an extraordinary statement issued by the club on Saturday, Sevilla pointed to the team receiving 91 yellows and 11 red cards despite committing just 329 fouls.

That aggregate of 102 cards is the most shown to any team in the Spanish top flight this term, despite 13 teams having more fouls to their name.

Sevilla sat 13th in the table after a 2-2 draw with Celta Vigo on Friday, in which Pape Gueye and Marcos Acuna were both dismissed and a 2-0 lead was relinquished in the closing moments.

This season's performance has been a frustrating one, after three consecutive fourth-placed finishes.

The club stated: "Sevilla FC want to place on record its deep concern and opposition to many of the refereeing decisions taken this season regarding the yellow and red cards issued to our players."

Sevilla said they "cannot agree with many of the decisions regarding the cards issued to our players, which in the long run has seriously harmed us in the league".

No team heading into Saturday's LaLiga games had received more red cards this season than Sevilla (Elche also had 11), while only Real Mallorca had been shown more yellows (98), which might be expected given they topped the fouls table (449).

"On average, one in three fouls committed by Sevilla FC results in a card," the club's statement added.

"Focusing on the match against RC Celta, Sevilla FC committed 11 fouls in the match and received four yellow cards and two reds, while Celta received two yellows for nine fouls committed.

"Sevilla FC are clearly not an aggressive team which is why these statistics are alarming.

"It is clear that many of these cards may have been for protesting, something that all players from all teams do, which shows that there is a lack of consistency in relation to protests or, to put it plainly, an outrageous leniency with some and a heavy-handedness with others."

Heading into Saturday's games, LaLiga had seen 108 red cards this season, compared to 28 in the Premier League, 33 in the Bundesliga, 50 in Serie A and 81 in Ligue 1.

While it used to be customary for LaLiga to see over 100 red cards brandished in a campaign, the three-figure threshold had not been passed in each of the last six seasons, with 103 reds in 2015-16 the last time such a figure was reached.

"The average figures for the Spanish league should lead to an urgent wake-up call," Sevilla added.

"La Liga is by far the league where referees show the most cards. The comparison with the Premier League, where a physical and much more contact-based style is played, speaks for itself: in the Premier League, with more matchdays played, 29 red cards have been shown to date; in La Liga, 108. More than triple.

"This is a striking difference. From Sevilla FC, we demand that these figures be analysed and that measures be taken when the decisions go against the spirit of the game.

"It is not about making excuses for the season the team is having. If Sevilla FC is where it is, it is based on sporting performance throughout the 28 league matches played, but it is about demanding equal treatment for all La Liga clubs and fairness when making decisions, something that unfortunately is not observed anywhere today."

UEFA has hit Eintracht Frankfurt and PSV with partial stadium closures after unsavoury scenes overshadowed European ties involving both clubs in February.

Both legs of Eintracht's 5-0 aggregate defeat to Napoli in the Champions League's last-16 were marred by violence, with clashes between supporters witnessed before the Partenopei's 2-0 away win on February 21.

Eintracht were subsequently charged with the lighting of fireworks and blocking of public passageways by UEFA, and the governing body has now fined the Bundesliga club a total of €70,000 and ordered them to close areas of Deutsche Bank Park for their next continental fixture.

The fear of further violence led Italian authorities to attempt to ban Eintracht supporters from travelling to Naples for the return fixture on March 15.

However, supporters clashed with local police after defying that measure, with footage on social media showing crowds throwing missiles at officers wielding riot shields.

Meanwhile, PSV have also been ordered to close sections of the Philips Stadion for their next UEFA game after a fan attacked Sevilla goalkeeper Marko Dmitrovic during a Europa League match.

PSV suffered a 3-2 aggregate defeat in the competition's knockout round play-offs, with the tie overshadowed by a supporter entering the pitch and throwing a punch at Dmitrovic in February's second leg in Eindhoven.

The 20-year-old man was given a two-month prison stint on March 8, as well as being made subject to a 40-year ban from PSV's stadium.

PSV have been fined €29,375 after UEFA investigated the incident, with the club also being charged with the throwing of objects at the same match.

With the last international window of the season over, domestic club campaigns now enter the final straight.

Everything is still to be decided – technically speaking. Title races, European qualification, relegation – all will come to a head over the next two months.

Of course, there are a few outcomes that already look like foregone conclusions, but there's still much to play for in each of the top five leagues.

With club football returning over the next few days, Stats Perform's Artificial Intelligence team have crunched the numbers using their supercomputer to predict the outcome of each league.

How's the outlook for your team?

Premier League

England is the scene of potentially most compelling title race among the top five leagues this season.

Arsenal may have an eight-point lead at the summit, but Manchester City still have a game in hand. As such, the Gunners' chances of winning a first league title since 2004 are 56.2 per cent, perhaps smaller than many might have expected.

That comes down in part to the statistical value attached to City's historic results, particularly over the past few years during their Premier League domination, whereas Arsenal haven't come close to that level of success over the same period.

Therefore, the title race still looks tight.

A little further back, Manchester United (74.5 per cent) are near-certainties to finish third, while the race for fourth promises to be engrossing – Tottenham (19.3 per cent), Newcastle United (29.1 per cent) and Liverpool (24.5 per cent) look set to tussle it out, with Brighton and Hove Albion (10.7 per cent) considered rank outsiders.

At the bottom, Southampton's 41.6 per cent likelihood of finishing 20th suggests they've a huge battle on their hands, but the supercomputer reckons West Ham and Leicester City have enough to pull themselves clear of the drop zone.

The signs are that two of Bournemouth, Everton and Nottingham Forest will join Saints in the Championship.

 

Bundesliga

Germany's top flight may come to rival the Premier League's title race. Ahead of the weekend's Klassiker between Borussia Dortmund and Bayern Munich, BVB are a point clear.

Yet, Dortmund's probability of finishing top is just 22.4 per cent compared to Bayern's 76.4. Again, it largely comes down to their historic results and Die Roten's dominance suggesting they'll eventually get the job done.

But it's fair to say Bayern's decision makers aren't so confident given their brutal choice to sack Julian Nagelsmann on Friday, replacing him with former Dortmund coach Thomas Tuchel.

Union Berlin aren't out of it given they are only five points behind Dortmund, though this is obviously uncharted territory for them, hence the 0.9 per cent chance of winning their first top-flight title since 1923.

Third looks the best bet for them (40.3 per cent), while RB Leipzig are the most likely to fill out the top four (37.2 per cent).

It's even tighter in the relegation scrap. Only seven points separate 18th from 13th, so even rock-bottom Stuttgart are given a reasonable chance of finishing 14th (10.6 per cent) or 15th (15.2 per cent).

 

LaLiga

Following Barcelona's dramatic 2-1 win in El Clasico before the international break, LaLiga looks done and dusted at the top with the Blaugrana 12 points clear.

The supercomputer also reckons Atletico Madrid are nearly guaranteed third (80.3 per cent), leaving what is effectively a two-horse race for fourth.

Real Sociedad have fourth at the moment and are 43.7 per cent likely to finish there, though Real Betis (36.7 per cent) aim to push them all the way.

At the other end, Elche are given no more than a 0.1 per cent chance of getting out of the bottom three after taking just 13 points from 26 games.

Otherwise, relegation is difficult to call. Almeria in 19th are only six points behind Real Mallorca in 11th, meaning there are a host of clubs who could yet get dragged into a fight for their lives.

There are two particularly big names among those potentially in trouble. Valencia are in the bottom three and have a 21.9 per cent chance of being relegated, while Sevilla – who are on their third coach of the season after sacking Jorge Sampaoli – are only two points clear of safety.

The computer says Man Utd's next Europa League opponents only have a 5.8 per cent probability of going down, however.

 

Ligue 1

Paris Saint-Germain seemingly have little to worry about in Ligue 1, with the supercomputer calculating their title chances at 98 per cent.

The tiny hint of doubt gives Marseille (1.8 per cent) and Lens (0.2 per cent) a bit of hope – but even then, it's presumably nothing more than a pipe dream.

There is a similar degree of certainty at the bottom, where four teams will be relegated ahead of the league's size being reduced to 18 clubs next term.

Angers, with 10 points from 28 games, cannot get out of the bottom four according to the calculations, and the other three positions are currently taken up by Ajaccio, Troyes and Auxerre.

Brest and Strasbourg aren't out of the woods yet either, though the supercomputer believes those in the relegation zone are the ones most likely to drop into Ligue 2.

 

Serie A

If there's one league in Europe that's got a foregone conclusion at the top, it's Serie A.

Napoli have more than a 99.9 per cent chance of winning a first Scudetto since 1990, with the unrelenting Partenopei a whopping 19 points clear of second already.

The race for Champions League qualification promises to be a little more tense.

Eleven points is the gap between Lazio in second and Juventus in seventh. While the Bianconeri are very much outsiders, the other five teams have at least a 15 per cent chance of finishing in the top four.

Lazio, Inter and Milan appear to be the most likely to take those spots, though Roma and Atalanta will fancy their chances of putting a cat among the pigeons.

In the relegation fight, there's a rather clearer picture.

Cremonese and Sampdoria look doomed, while Hellas Verona in 18th are five points adrift of safety, giving them just an 18.8 per cent probability of avoiding relegation.

 

Sevilla have confirmed the appointment of Jose Luis Mendilibar as coach on a short-term contract after sacking Jorge Sampaoli.

A dismal run of form has seen Sevilla lose four of their last seven LaLiga games and they sit just two points above the relegation zone.

Sampaoli's second spell at the club came to an end on Tuesday following a 2-0 defeat at Getafe, which proved the final straw.

The Argentine replaced Julen Lopetegui in October but managed just six wins out of 19 LaLiga matches in charge, although he did lead Sevilla into the Europa League quarter-finals.

Sevilla moved quickly to confirm a replacement, with former Real Valladolid, Alaves and Eibar boss Mendilibar drafted in on a contract until June 30.

His first match in charge will be after the international break, with Sevilla visiting fellow strugglers Cadiz. They then host Celta Vigo on April 7 before travelling to Old Trafford for the first leg of their Europa League quarter-final tie against Manchester United six days later.

Mendilibar has overseen 448 LaLiga games as a coach, winning 128 and losing 195.

Jorge Sampaoli has been sacked by Sevilla after a poor run of form left them just two points above the relegation zone in LaLiga.

A 2-0 defeat at fellow strugglers Getafe on Sunday proved the final straw for Sampaoli, who had only returned for his second spell in charge in October.

Sevilla have won just twice in their past seven LaLiga matches, losing four games in that run.

Sampaoli did steer Sevilla into the quarter-finals of the Europa League, but a different coach will now be in the dugout when they go head to head with Manchester United.

A Sevilla statement read: "Sevilla have terminated the contract of coach Jorge Sampaoli after the team's defeat in Getafe, which has once again placed the team on the verge of relegation places.

"The fact that the team has not managed to get out of the lowest positions in the table since his incorporation as coach and the image offered in the last matches of the team have led the club to make this decision, in search of a reaction in the 12 games that remain in the league.

"Sevilla thanks Sampaoli for the services he has provided and wishes him the best of luck in his future."

The club said they planned to appoint a new coach later on Tuesday, to be in charge in time to take an early-evening training session. Former Real Valladolid and Eibar boss Jose Luis Mendilibar has been strongly linked with the job.

Sampaoli was first put in charge in Sevilla ahead of the 2016-17 season and led them to a fourth-placed finish in LaLiga before leaving to take over as Argentina head coach.

PSV have handed the man who attacked Sevilla goalkeeper Marko Dmitrovic during their Europa League meeting a 40-year stadium ban. 

The Eredivisie club were eliminated from the competition despite a 2-0 second-leg victory in their knockout round play-off tie last month at Philips Stadion, having lost 3-0 in Spain.

Ugly scenes marred the final moments of clash in Eindhoven, however, when a 20-year-old supporter entered the pitch and attacked Dmitrovic, who subsequently pinned the man before security escorted him away.

The man in question was given an initial two-month prison stint on March 8, and sentenced to an additional one-month inside if he re-offends.

PSV have now confirmed he will face further long-term punishment for his actions, with a stadium ban stretching until 2063.

"PSV [have] imposed a 40-year-long ban on the individual who invaded the pitch during the Europa League match against Sevilla," the club said in a statement.

"The 40-year-long ban comes on top of a possible fine imposed by UEFA. The pitch invader is currently serving a three-month sentence with one month suspended imposed by the East Brabant District Court.

"He is also barred from the area around the stadium for two years."

PSV also revealed the individual had already been serving a ban from the Royal Dutch Football Association (KNVB).

Sevilla secured their place in the quarter-finals of the Europa League last week following a 2-1 aggregate victory over Fenerbahce.

They will face Manchester United in the last eight in April, after the international break.

Manchester United must overcome Europa League specialists Sevilla in order to reach a semi-final against either Juventus or Sporting CP.

United defeated Real Betis in the last 16 and will now face their city rivals Sevilla, six-time winners of the UEFA Cup and Europa League.

The sides have met three times previously, with Sevilla knocking United out of the 2017-18 Champions League over a two-legged tie before beating the Red Devils again in a one-off 2019-20 Europa League semi-final.

It is a daunting draw for United, who could then have to play Juventus in the last four.

The semi-final draw, which was also conducted on Friday, paired the winners of United's tie with Juventus or Sporting, who eliminated Arsenal on Thursday.

Even in the final, should Erik ten Hag's men make it that far, United could be set for a reunion with former manager Jose Mourinho.

Mourinho's Roma were drawn against Feyenoord in the quarter-finals in a repeat of last season's Europa Conference League final, which the Giallorossi won.

Bayer Leverkusen meet Union Saint-Gilloise in the final last-eight tie, playing for the right to face Roma or Feyenoord.


Europa League quarter-final draw in full:

Manchester United v Sevilla
Juventus v Sporting CP
Bayer Leverkusen v Union Saint-Gilloise
Feyenoord v Roma

Diego Simeone set a new record for matches in charge of Atletico Madrid on Saturday and his players provided a stunning tribute as they crushed Sevilla 6-1 at the Civitas Metropolitano.

Simeone, 54, was presiding over his 613th match as Atletico coach, breaking the record set by the late Luis Aragones.

He was handed with a framed commemorative jersey with "Legend, Simeone, 613" across the back before the LaLiga game, with Aragones' son and three of Simeone's children joining him for the presentation.

Simeone's side followed that up with a fitting homage as they brutally swept aside another of their coach's former clubs.

Memphis Depay scored twice in quick succession before the half-hour mark, his second an emphatic strike from the edge of the box, with Youssef En-Nesyri halving the deficit from close range late in the half.

Atletico need not have worried, however. Antoine Griezmann restored the two-goal lead early in the second half and Yannick Carrasco made it 4-1.

Alvaro Morata netted twice late on – his first coming just after Ivan Rakitic missed a penalty – to wrap up a memorable victory on a momentous day for Simeone.

"A night to enjoy and one that [Simeone] will surely not forget," club captain Koke told Movistar after the game. "But hey, I'm sure he's already thinking about the Girona game because his philosophy in life is like that.

"Bygones are bygones, and he always looks to the next game."

He added: "You can't imagine an Atletico Madrid without Simeone. I've been here for 11 years, he came with a very clear idea, he changed the mentality, brought us all together, given the club the stability it needed and hopefully it will continue for many years.

"He has a year and a half left on his contract and we'll see what happens later."

Griezmann celebrated his goal by running over to Simeone and wrapping him in a huge hug.

Explaining the gesture, Griezmann said: "What is an important day for him is an important day for me. I wanted it to be a magical day for the fans and for my team-mates."

For Simeone, however, his focus turned to Aragones, whom he was coached by as a player at Sevilla.

Aragones died in February 2014, but ahead of Saturday's game Simeone posted a letter to him on social media, an act the Argentinian felt was necessary to outline his emotions.

Discussing the letter after the Sevilla game, Simeone told reporters: "Explaining feelings and emotions is difficult.

"I had no doubts seven or eight days ago, I began to think about what was happening and I understood that there was a person before everything that I had to write to, Luis. I talked about it with the family and they said it was a good idea.

"Why? We have travelled the same path; that respect for an eternal person; and passing the point that places me – by numbers, not by capacity – in the history of Atletico.

"Where I am, [Aragones] knows the difficulty. He knows the anger, the egos, living with the emotions, what the club needs, the coaching staff, that we must not make mistakes, that I must say the right word at the right time.

"We have made mistakes several times, but I am calm, I am at peace, because I am in the place where I want to be, I do what I like.

"I am excited to see when the team stands up and continues fighting until the end."

UEFA has launched an investigation after Sevilla goalkeeper Marko Dmitrovic was punched by a PSV fan during Thursday's Europa League match.

The on-field skirmish came near the end of the game, which saw PSV win 2-0 but suffer a 3-2 aggregate elimination against their LaLiga opponents.

Dmitrovic pinned down the pitch invader and held him to the ground before security arrived to escort him away.

UEFA is understood to have opened a case following the incident, which has been condemned by PSV, who said the fan should not have been in the stadium in the first place.

The Dutch club said in a statement: "PSV strongly condemn the incident on Thursday evening when a man invaded the pitch and confronted the goalkeeper. The person involved had already been handed a stadium ban."

PSV general manager Marcel Brands said: "This  is not what we stand for at PSV. We feel ashamed and there is no place for that type of behaviour.

"We will consult the organisations involved to discuss how we can enforce stadium bans better, hopefully through reporting obligations. All PSV supporter organisations, who cheered on their team last night, unanimously and explicitly distance themselves from this disgraceful pitch invasion."

PSV said they would "await the investigations into the pitch invader made by the police and look to recover any financial damages".

Sevilla have been drawn to face Turkish Super Lig outfit Fenerbahce in the last-16 stage.

Six-time champions Sevilla are looking to extend their record haul in the competition, which began in its previous guise as the UEFA Cup, having last lifted the trophy in 2020 against Inter.

Manchester United have been drawn to face Real Betis in the Europa League's round of 16, while Arsenal will battle Sporting CP for a quarter-final spot.

United came from behind to clinch a 2-1 victory over Barcelona at Old Trafford on Thursday, and their reward for a 4-3 aggregate triumph over the Blaugrana is a tie against another Spanish opponent.

Having not lifted any silverware since winning this competition in 2017, United are in the hunt for four trophies this term, though Erik ten Hag's men will be tested by a side sat fifth in LaLiga.

Betis boss Manuel Pellegrini has faced United on four previous occasions in European competitions, with all four games finishing goalless during his time with Villarreal (in the 2005-06 and 2008-09 Champions League group stages).

Premier League leaders Arsenal will face Sporting after Ruben Amorim's team thrashed Midtjylland 5-1 on aggregate in the knockout round play-offs.

Sporting have progressed from each of their previous six ties against English teams in the knockout stages of the UEFA Cup/Europa League, with all six coming against different teams.

The other standout last-16 ties see Juventus meet Freiburg, while Jose Mourinho's Roma will take on Real Sociedad as they bid to follow up last season's inaugural Europa Conference League triumph.  

Feyenoord, who Roma beat in the final of that competition, have been paired with Shakhtar Donetsk, while surprise Bundesliga challengers Union Berlin will face Belgium's Union Saint-Gilloise.

Six-time winners Sevilla – the most successful club in UEFA Cup/Europa League history – will face Fenerbahce, while Bayer Leverkusen will take on Ferencvaros. 

The first legs of the last-16 ties will take place on March 9, with the group-stage winners hosting the return fixtures one week later. 

Europa League last-16 draw in full

Bayer Leverkusen v Ferencvaros
Juventus v Freiburg
Manchester United v Real Betis
Roma v Real Sociedad
Sevilla v Fenerbahce
Shakhtar Donetsk v Feyenoord
Sporting CP v Arsenal
Union Berlin v Union Saint-Gilloise

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