After making their Concacaf Gold Cup return and debut respectively, Grenada and Qatar face off for the first time as Group D action resumes on Saturday night at BBVA Stadium in Houston, Texas.

Panama came from behind three times to draw with Qatar, while Honduras swept aside Grenada 4-0 in their opening CONCACAF Gold Cup matches on Tuesday.

In a tight game in Houston, six goals were scored in the second half as 2022 World Cup hosts Qatar hit the lead three times but failed to capitalise.

Panama's Rolando Blackburn levelled the game twice in a flurry of goals in the first 20 minutes after half-time, as Hassan Al Heidos put Qatar up 3-2 from the spot in the 63rd minute. Eric Davis equalised with a 79th-minute penalty.

Honduras dominated Grenada in the later game, with goals from Jerry Bengtson, Edwin Solano, Johnny Leveron and Romell Quioto.

Panama and Honduras will meet on Saturday in Houston after Grenada and Qatar face off at the same venue.

Australia have joined Qatar in withdrawing from the 2021 Copa America.

The Socceroos and the 2022 World Cup hosts had been scheduled to contest the tournament, due to be held in Argentina and Colombia in June and July, as invited guests of CONMEBOL.

However, the postponement of the remainder of the second round of AFC qualifying for the World Cup until June because of the COVID-19 pandemic has led both teams to pull out.

Qatar, who announced their withdrawal on Tuesday, are competing in the qualifying process to secure a place in the 2023 Asian Cup. They are top of Group E and will seal their spot if they win it.

Australia are top of Group B and on course to qualify for the Asian Cup and progress to the third round of the World Cup qualification progress.

"The Socceroos' players and staff were greatly looking forward to the unique opportunity of playing in the Copa America and it is unfortunate that, due to the COVID-19 pandemic, we will be unable to attend in 2021," Australia coach Graham Arnold said.

"On behalf of the team I thank CONMEBOL for the invitation, which would have presented our team with a fantastic opportunity to test itself against some of the world's best."