Emma Raducanu retired from her first-round match with Bianca Andreescu at the Internazionali d'Italia because of a lower back injury.

The world number 12 was trailing 6-2 2-1 when calling time on the match against Andreescu in a highly anticipated showdown between two of the past three US Open winners.

Raducanu initially left the court for treatment ahead of the seventh game of the opening set for a medical timeout and completed just four more games.

Speaking after her withdrawal, coming two weeks before the French Open, Raducanu explained she did not want to aggravate an injury sustained at last week's Madrid Open.

"I thought maybe taking one, two days off, it would go away because a lot of the other small niggles I've had, they've kind of gone away after taking, like, two days off," she said.

"Then I got here and I was training, but it just didn't seem to get better. I was training with some limitations. I wasn't moving really.

"I was just playing where I knew where the ball was coming, just staying in one corner. I think I must have underestimated the unpredictability of competition in a match.

"The last few weeks have been really positive. I've learned a lot about myself and my game has definitely improved on this surface but I need to make sure my back is fully right.

"I need to just keep on it. I don't want to play my next match with a feeling of limitation because I think that I learned my lesson from this week, when to push, when not to push." 

Ons Jabeur joined Andreescu in the last 32 with a 6-0 7-6 (7-1) victory over Sorana Cirstea to keep her impressive run of form going.

The Tunisian won her first WTA 1000 title in Madrid last week and has now won seven successive main draw matches for the first time in her career

Elsewhere in Tuesday's action, American qualifier Lauren Davis pulled off a shock 6-2 6-3 win against number 11 seed Jelena Ostapenko.

Fellow Americans Jessica Pegula, Madison Brengle and Amanda Anisimova also advanced, beating Liudmila Samsonova, Marta Kostyuk and Tereza Martincova respectively.

Anisimova, who is now the player with the most wins in three sets so far in 2022 with nine, will face Belinda Bencic for a place in the last 16.

Ons Jabeur became the first player representing an African country to land a WTA 1000 title as she fended off Jessica Pegula in the Madrid Open final.

The Tunisian beat her American opponent 7-5 0-6 6-2, regrouping well after a major dip in the second set to scoop the biggest title of her career.

The history-making victory means Jabeur will jump from 10th to seventh in the WTA rankings on Monday, matching a career high, and she earns €1,041,570 in prize money.

After losing to Belinda Bencic in the Charleston Open final last month, Jabeur's run on the Spanish clay shows she is becoming increasingly resilient, and comes as a timely boost ahead of the French Open getting under way in two weeks' time.

"We've lost a lot of finals, but today I'm happy I pulled out the win," Jabeur said at the end of the match, addressing her support team.

"It was very tough, especially last time in Charleston, so thank you guys for always believing in me and pushing me forward."

Jabeur came from 4-1 behind to take the opener, and she now holds a 17-0 match record when winning first sets this year.

Pegula broke in the fourth game, having fended off three break points in the opening game of the contest. Jabeur hit back and soon had the match back on serve, before saving a set point with a thumping backhand.

The 28-year-old Pegula, daughter of Buffalo Bills owners Terry and Kim Pegula, has carved out a successful career at the top level in tennis, reaching back-to-back Australian Open quarter-finals this season and last.

She was in trouble when she lost her serve in the 11th game though, and Jabeur capitalised to snatch the opener.

Pegula made a flying start to the second set, establishing a swift double break, and a flat Jabeur found no way back. A drop shot into the net on set point summed up her drastic drop in level.

Jabeur stopped the rot by breaking serve at the start of the decider. Pegula immediately got back on level terms, but another break for Jabeur saw her pull away, on her way to victory in an hour and 54 minutes, a tour-leading 12th win of the season on clay.

The impressive Jabeur is also the first Arab winner of a tournament at this lofty level.

Ons Jabeur became the first player representing an African nation to reach the final of a WTA 1000 tournament as she set up a clash with Jessica Pegula at the Madrid Open.

Tunisian Jabeur, who beat Olympic gold medallist Belinda Bencic and two-time grand slam winner Simona Halep to reach the semi-finals, needed just an hour and one minute to secure a routine last-four win over Ekaterina Alexandrova.

The world number 10 dominated her Russian opponent in a 6-2 6-3 win, before setting her sights on victory in what will be her sixth career final on the WTA Tour but first at such a high tier.

"I'm going to put a positive here. I want to win this final," Jabeur said after her win. "I'm going to put my heart, my favourite drop shot, my forehand in.

"I'm just going to really give my best. I don't want to regret [anything]. The main important thing for me, I know it's winning the title, but [also] knowing that I gave it all during the match and not regretting that. I know if this one [title] is not coming, then there is another one.

"I keep pushing myself to do better. The proof is that from Charleston [where Jabeur lost the final to Bencic last month], I worked really hard to be in the finals here. Like I said, I'm going to leave my heart on the court on Saturday."

Jabeur will face American Pegula in Saturday's final after she registered a 6-3 6-4 triumph over Switzerland's Jil Teichmann.

The 12th seed was tested when Teichmann fought back from a break down to 4-4 in the second set, with 28-year-old Pegula managing to dig deep to break once more and reach what is also her first WTA 1000 final.

Saturday's contest will represent just the fourth final of Pegula's career, and the first since losing to compatriot Serena Williams in straight sets at the 2020 Auckland Open, but she will enter the top 10 of the WTA rankings with a win.

"I knew I was close to the top 10, but it's so hard, you have to step up and do really well to win a tournament," Pegula said on court.

"I'm just so happy to be in the final, it's my first final in a 1000. I've been knocking on the door in the last few tournaments, [but] I was able to take care of business today."

Jabeur and Pegula have met on four previous occasions with each player boasting two victories each, Jabeur winning their last meeting at the last-16 stage of this year's Dubai Tennis Championships.

Ons Jabeur produced a fine display as she made light work for Simona Halep to secure her place in the Madrid Open semi-finals.

Former world number one Halep was the only player to have won the competition to have reached the last eight, but she was no match for the Tunisian, who won 6-3 6-2 in just over an hour.

After a difficult start to the year, Jabeur has hit her stride in recent times and will be contesting a second semi-final in three tournaments.

While Jabeur caught the eye, particularly with her penchant for a dropshot, Halep proved to be her own worst enemy, recording 12 more unforced errors (20) than winners (eight).

Up next for Jabeur is qualifier Ekaterina Alexandrova, who beat 2019 French Open semi-finalist Amanda Anisimova 6-4 6-3 to reach her first WTA 1000 last-four clash.

Alexandrova has won six of her previous seven meetings with Jabeur.

Meanwhile, Anhelina Kalinina saw her impressive run ended by Jil Teichmann. The Ukrainian had seen off three major winners on the bounce in Sloane Stephens, Garbine Muguruza and Emma Raducanu, but she was beaten in straight sets this time.

Teichmann – who won 6-3 6-4 – will face Jessica Pegula for a place in the final, with the American eliminating Spain's final hope of a home winner in Sara Sorribes Tormo, 6-4 6-2.

Ons Jabuer avenged her recent loss to Belinda Bencic with a win at the Madrid Open, while Coco Gauff is out after being beaten in straight sets in the round of 16 by Simona Halep on Monday.

Gauff joins other big names in exiting the WTA 1000 event, with Naomi Osaka, Garbine Muguruza, Danielle Collins, Paula Badosa and Maria Sakkari among those crashing out in the second round.

The number 14 seed did not put up much resistance against her Romanian opponent, with Halep winning 6-4 6-4 in just 77 minutes.

Gauff struggled on her own serve in particular, making six double faults and only winning 61.5 per cent of her first-serve points, compared to 83.8 from Halep on hers.

The former world number one and two-time Madrid champion will now face the only remaining top-eight seed in the tournament in the quarter-final, Jabeur, who defeated Bencic 6-2 3-6 6-2.

The Tunisian was out for revenge after losing to Bencic at the same stage last year, as well as in the Charleston Open final last month, and took it well as she sealed victory in just over two hours.

"I came here to take my revenge," Jabeur said after the win. "I wish I played like that in the final in Charleston, to be honest.

"Part of me is very proud of myself for coming today and getting the win. Belinda is such an amazing player and it's very tough to play against her. I'm very happy with the level I showed today, and hopefully this level will continue for the rest of the tournament."

Elsewhere, Victoria Azarenka is out after the number 15 seed was beaten 6-1 6-4 by Amanda Anisimova, who will now face Ekaterina Alexandrova in the last eight after she overcame Marie Bouzkova 6-7 (4-7) 6-0 7-5.

Simona Halep blew Paula Badosa away with a Madrid Open masterclass to reach the round of 16 on Saturday.

Second seed Badosa had no answer to the brilliance of Halep in her homeland as the relentless Romanian won 6-3 6-1 at the Caja Magica.

Unseeded two-time grand slam champion Halep took just an hour and 17 minutes to eliminate Badosa, breaking three times in the first set and twice in the second.

Halep, in a new era with Patrick Mouratoglou in her corner, won 84 per cent of points when she landed her first serve in, staying in the hunt to win this tournament for a third time with the French Open on the horizon.

The former world number one will face Coco Gauff for a place in the quarter-finals following the American's 6-1 2-6 6-4 late-night defeat of Yulia Putintseva.

Gauff, the 14th seed, racked up 10 double faults and was pushed all the way by Putintseva, but served out the match after securing a third break in a tight final set.

Ons Jabeur earlier advanced into the third round at the expense of Varvara Gracheva, recovering from a second-set bagel to win 7-5 0-6 6-4.

Jabeur faces a meeting with Belinda Bencic after the Swiss dispatched Karolina Muchova 6-3 4-6 7-5.

Victoria Azarenka came from a set down to beat Tamara Zidansek 3-6 6-1 6-3 to set up a meeting with Amanda Anisimova, who also had to come from behind to dispatch Petra Martic 3-6 6-3 6-2.

Ekaterina Alexandrova and Marie Bouzkova also progressed in the Spanish capital.

Amanda Anisimova celebrated her fifth career top-10 win by beating Aryna Sabalenka again at the Madrid Open.

The 20-year-old American would have headed into Thursday's match-up full of confidence having also defeated the world number four in Charleston earlier this month.

And again Anisimova came out on top, this time at a tournament where Sabalenka was the defending champion.

Sabalenka is now 0-4 against Anisimova, losing three times on clay, with this the underdog's first ever victory in Madrid.

A 6-2 3-6 6-4 triumph was sealed in an hour and 55 minutes, with Anisimova relishing the opportunity to take on one of the sport's foremost stars once more.

"It's always enjoyable to accept the challenge, even when it's a tough match, and push yourself and see how far you can go," Anisimova said.

"I enjoy these matches, even though they're very tough – especially when you get to win them."

While Anisimova can look forward to facing Petra Martic in round two, hers was not the only upset win, with Karolina Pliskova and Jelena Ostapenko also ousted.

Pliskova lost in straight sets to fellow Czech Marie Bouzkova, as Ostapenko went down in three to Ekaterina Alexandrova.

Simona Halep and next opponent Paula Badosa both came through unscathed, though, as did Belinda Bencic, Coco Gauff and Ons Jabeur.

Jabeur's 11-9 first-set tie-break success against Jasmine Paolini was the closest any of that quintet came to dropping a set on day one.

Belinda Bencic continued her strong run of form in the United States as she defeated world number 10 Ons Jabeur 6-1 5-7 6-4 to win the Charleston Open.

Sunday's success made it 10 victories from her past 11 matches for Bencic, with the lone defeat coming in a semi-final against Naomi Osaka at the Miami Open.

The Swiss Olympic gold medallist flew out of the gates in the opening set, winning 80 per cent of her points on serve (16 of 20) and breaking Jabeur twice.

It was a far more competitive second set as Jabeur's return game improved, the Tunisian also saving six of eight break points to force a decider.

Bencic prevailed in a rollercoaster of a third set, where Jabeur converted two breaks of serve, but the eventual champion managed three, finding a response every time she was challenged.

Jabeur becomes the second top-10 scalp claimed by Bencic this tournament after also defeating world number three Paula Badosa in three sets in the quarter-finals.

Belinda Bencic wondered if she would ever be able to compete for titles on clay but will do exactly that on Sunday.

The Swiss reached her first ever WTA Tour final on the red dirt of the Charleston Open, beating semi-final opponent Ekaterina Alexandrova 6-4 6-3.

Although she has four WTA titles to her name, this was only Bencic's third last-four appearance on clay – losing the prior two, including a 2014 Charleston challenge as a 17-year-old.

But she finally has glory in her sights, and the omens are good for the final, facing Ons Jabeur having won their only prior meeting in 2021 at the Madrid Open, another clay-court event.

"I'm happy this moment came," Bencic said. "I didn't think it would, but I'm super happy with how I played today. I thought it was a great match in tough conditions."

Bencic needed only 78 minutes to complete the job, but Jabeur found life tougher, forced to rally from a set down to Amanda Anisimova.

The 20-year-old American had herself recovered to eliminate top seed Aryna Sabalenka earlier in the tournament but was now on the wrong side of such a comeback.

Jabeur, who lost in the final of the WTA 250 Charleston Open II last year, prevailed 2-6 6-1 6-4.

Meanwhile, at the Copa Colsanitas, there will be no repeat win for Camila Osorio after the defending champion and top seed lost to Laura Pigossi in straight sets in the semis.

Tatjana Maria is now Pigossi's opponent in the title match.

Belinda Bencic has beaten world number three Paula Badosa 2-6 7-6 (7-2) 6-4 to move on to the semi-finals of the Charleston Open.

Bencic, the 10th seed, appeared overmatched early on as she won less than half (12-25) of her service points in the opening set, getting her serve broken twice.

But as Bencic found her rhythm with her serve – winning 77 per cent of her first-serve points in the second set (24-31) – she wrestled the momentum away from Badosa, dominating the tie-break before breaking in the opening game of the third frame.

Bencic will face Ekaterina Alexandrova in the semi-final after the Russian dominated Magda Linette 6-0 6-2.

For the match, Alexandrova won 62 per cent of her points on serve (28-45) and 62 per cent of her points on return (26-42).

Fourth seed Ons Jabeur needed just 64 minutes to get the job done 6-3 6-2 against Anhelina Kalinina, winning 81 per cent of her successful first serves (29-36).

Jabeur will play 15th seed Amanda Anisimova in the semi-final after the American cruised past compatriot Coco Vandeweghe 6-1 6-2.

It was not a perfect performance from Anisimova, but she saved all five break points that she faced to never allow her opponent to get close.

Meanwhile, in Bogota at the Copa Colsanitas, top seed Camila Osorio is through to the semi-final after defeating Elina Avanesyan 6-1 6-4, where she will meet Laura Pigossi.

World number five and the tournament's top seed, Aryna Sabalenka, was upset by American Amanda Anisimova 3-6 6-4 6-3 in the third round at the Charleston Open.

Sabalenka's serve was the key to her early success, connecting on 73 per cent of her first serves, and winning 15 of the 19 points in that situation (79 per cent).

When Sabalenka's first serve percentage fell to 48 in the second set, Anisimova found her footing, breaking twice in the frame, before pouncing on the Belarusian's lacklustre second serve in the deciding set, winning seven of nine opportunities to earn the break and the win.

Sixth seed Jessica Pegula was also bounced in surprising fashion, losing 6-4 3-6 6-4 to unseeded compatriot Coco Vandeweghe.

In a razor-close contest, it came down to who took their chances, as Vandeweghe saved seven of the 10 break points she faced, while Pegula could only save one of five.

World number 10 Ons Jabeur had no problem navigating the challenge of Emma Navarro, winning 6-3 6-2 as she broke her opponent's serve on six occasions.

Canadian seventh seed Leylah Hernandez also fell victim to an unseeded upset, going down 3-6 6-3 6-4 against Poland's Magda Linette.

In a meeting between two top-10 seeds, Belinda Bencic got the better of Madison Keys to edge it 6-4 6-4.

Second seed Paula Badosa had to come from a set down to eventually get the better of Claire Liu 3-6 7-6 (10-8) 6-1.

In the late session, French 12th seed Alize Cornet went down in a close tussle against Ukraine's Anhelina Kalinina 7-6 (7-5) 7-5, while Jabeur won her second match of the day, beating Irina Begu 6-3 6-2.

Meanwhile, in Bogota at the Copa Colsanitas, top seed Camila Osorio dispatched Turkish opponent Ipek Oz 6-3 7-6 (7-4) to move on to the quarter-final where she will meet Elina Avanesyan.