Tom Brady became the first player in NFL history to reach 100,000 passing yards during the first/second/third/fourth quarter against the Los Angeles Rams on Sunday.

The Tampa Bay Buccaneers quarterback was always likely to hit the landmark in the 2022 season, and the 45-year-old did exactly that against the Rams, achieving a feat that may never be matched.

Brady entered the Week 9 clash with 86,787 passing yards in the regular season, adding 13,049 yards in the postseason.

He stands more than 14,000 yards ahead of the second-placed quarterback all-time in that regard, Drew Brees.

Only once in the past 12 seasons has Brady failed to rack up more than 4,000 passing yards for the campaign, finishing with 3,554 in the 2016 season for the New England Patriots after missing the first four games due to his Deflategate suspension. Brady ended that season by leading the Patriots back from a 28-3 deficit to defeat the Atlanta Falcons in Super Bowl LI.

Despite the Bucs struggling mightily on offense in 2022, Brady is on pace to hit the 4,000 mark again this season, having entered Week 9 with 2,267 to his name.

Last season, Brady became the first player to throw 700 career touchdown passes, and when he does retire for good after swiftly reversing his decision to hang up the cleats this past offseason, he will undoubtedly do so as the greatest of all time.

The Los Angeles Rams and Tampa Bay Buccaneers meet in Week 9 in a matchup between two preseason NFC favourites who have spectacularly failed to live up to expectations.

Los Angeles and Tampa Bay produced a thrilling NFC Divisional Round playoff game last season, the Rams prevailing in overtime following a furious Bucs comeback en route to winning Super Bowl LVI.

Such excitement has been thin on the ground for both teams in 2022. They are a combined 6-9, with both of their offenses enduring significant struggles. 

Last week, the Rams (3-4) were thrashed 31-14 by their NFC West rivals the San Francisco 49ers, who completed a fourth successive regular-season sweep of Los Angeles.

That defeat marked the fourth time this season the Rams have scored 14 or fewer points and lost by double-digits. From 2017 through 2021 (head coach Sean McVay’s tenure prior to this season), they had six such games. Five of those 10 games have been against San Francisco.

Quarterback Matthew Stafford threw for 187 yards on 33 attempts against San Francisco. It was the 11th time in his career that he has thrown the ball at least 30 times and finished with fewer than 200 passing yards. His teams are 2-9 in those games.

Stafford averaged 4.71 air yards per attempt in the loss to the 49ers, the Rams' offense relying largely on the screen pass and rendered impotent in the second half after San Francisco succeeded in taking that away.

Los Angeles' lack of counterpunches when the Rams cannot get the ball to Cooper Kupp should offer the Tampa Bay defense, which is allowing the fourth-fewest yards per pass play (5.7) in the NFL, confidence it can contain Stafford and Co. as the 49ers did.

The Rams' distinct lack of a running game -- Los Angeles' run success rate of 24.3 per cent is by far the worst in the league -- will only further Tampa Bay's confidence in that regard, and the Buccaneers appeared closer to solving their problems on offense in Week 8.

Though the Buccaneers (3-5) lost for the third consecutive game, suffering a 27-22 defeat to the Baltimore Ravens, Tom Brady threw for 325 yards and zero interceptions. In his career, he is 54-7 when throwing 300 yards and no interceptions but is 1-2 in such games this season.

Still, Tampa Bay's three-game losing streak is their longest such run since the Buccaneers lost four in a row between Week 5 and Week 9 in 2019. In addition, they have scored 28 points just once this season, in a 41-31 loss to the Kansas City Chiefs. The Bucs were 12-0 when reaching that mark last season.

Both offenses appear likely to face plenty of third-and-long situations, and it may be the offense that does a better job of overcoming them that comes out on top.

The Buccaneers are five of 50 (10 per cent) on third down with six or more yards to go. That percentage ranks last in the NFL. The Rams' 17.5 per cent mark (7-for-40) is 28th in the NFL. Last season, the Rams were third at 35.0 per cent while the Bucs were 12th at 25.6 per cent.

It's a tale of two offenses experiencing a substantial downturn, but neither team is dead in the water, with the Buccaneers one game out of the NFC South lead and the Rams a game back in the loss column in the NFC West, which is led by the 5-3 Seattle Seahawks.

But time is running out for these teams to right their respective ships, and the loser of this game will be at significant risk of sinking out of contention even in an open NFC.

After a busy NFL trade deadline, the focus is back on the field this weekend.

Josh Allen faces Zach Wilson as the New York Jets confront a major test of their defense against the soaraway Buffalo Bills, while the Los Angeles Rams will look to keep up their remarkable record against the Tampa Bay Buccaneers.

Could Derrick Henry have another monumental game in him after last week's big effort, and after he dispelled worries about a foot problem?

Stats Perform has taken a look at the numbers ahead of Sunday's games, beginning with the travails of the Brady bunch.

Los Angeles Rams (3-4) at Tampa Bay Buccaneers (3-5)

The Buccaneers are on the slide, and the Rams are just about the nightmare opponents this weekend, judging by recent games between the teams.

Including Los Angeles' win in last season's Divisional Round, the Rams are 9-1 in their last 10 games against the Bucs, and that includes a 5-0 streak in Tampa.

This game is big for both, and for the Bucs it offers a chance to halt a losing sequence of three. They were beaten 27-22 by the Baltimore last week and are on their longest single-season losing run since a dismal four-game run in the 2019 season.

It remains to be seen whether Tom Brady can get them out of this mess. Brady threw for 325 yards and zero interceptions in last week's loss to Baltimore. Across his stellar career, he is 54-7 when throwing 300 yards and no interceptions, but this season he is 1-2 in such games.

Brady might fancy the job against a Rams team who have scored 14 or fewer points and lost by double-digits four times already this season, including last time out in a 31-14 home loss to the San Francisco 49ers.

Rival quarterback Matthew Stafford threw for 187 yards last week on 33 attempts. His team are 2-9 in games where Stafford has thrown the ball at least 30 times and finished with fewer than 200 passing yards.

Buffalo Bills (6-1) at New York Jets (5-3)

The Buffalo Bills are 6-1 for the first time since 1993, the season they last made it through to the Super Bowl. This weekend they go after a fifth win in a row after getting the better of the Green Bay Packers last time out.

What's more, they have strung together a four-game winning streak in road games against the Jets, second only in franchise history to a seven-game streak from 1987 to 1993.

The Bills have outscored this season's opponents by 105 points (203-98) so far, the widest differential in the NFL.

Bills quarterback Josh Allen has urged the Jets to show patience with his struggling counterpart Zach Wilson, who has completed just 54.9 per cent of passes this season, the second-worst rate in the NFL heading into Week 9. Wilson has thrown for 1,048 yards across five games, with three touchdowns and five interceptions, compared to Allen's 2,198 yards for 19 TDs and six interceptions from seven games.

Stefon Diggs has at least 100 yards and a receiving touchdown in three straight games, the longest streak of the Bills wide receiver's career and tied for the longest streak in team history with Elbert Dubenion (1964). The last NFL player with a longer streak was Adam Thielen in 2018 (five). How Diggs fares against Jets rookie cornerback Sauce Gardner will be a factor.

The Jets have already topped last season's four wins, but they are 8-30 against divisional opponents since 2016, the worst record in the NFL.

Tennessee Titans (5-2) at Kansas City Chiefs (5-2)

What does Titans running back Henry have in store for an encore? Henry last week recorded his sixth career 200-yard rushing game, with 219 yards and two touchdowns against the Texans, tying Adrian Peterson and O.J. Simpson for the most all-time. All other active players have combined for just four such games.

The Chiefs will be wary of that threat, and will look to their own WR, JuJu Smith-Schuster, to make his own impact. After failing to reach 90 yards or find the endzone in his first five games this season, Smith-Schuster now has back-to-back games with at least 100 yards and a touchdown. He had not had such a game since Week 8, 2019 and now has eight such games in his career.

The Titans have won four straight regular season matchups with the Chiefs but lost in the 2020 AFC Championship Game in Kansas City.

Their respective 5-2 records this season disguise the fact each of those wins has been relatively close. The Titans and Vikings have only won by single digits this season. Only five teams in NFL history have seen such a streak reach six games – the 2020 Chiefs, 1997 Vikings, 1994 Giants, 1988 Saints and 1986 Giants. Of those, only the Chiefs' streak reached seven.

Elsewhere...

The Miami Dolphins (5-3) will be looking for a fourth consecutive road win against the Chicago Bears (3-5), which would make the Dolphins the first AFC team since the conference came into being in 1970 to have such a streak in Chicago. Miami's Tyreek Hill has gone 52 consecutive receptions without a receiving touchdown. That accounts for the longest streak of his career, nearly doubling his previous career-long streak (27, twice).

Memories of a record-setting 2014 game between the Carolina Panthers and the Bengals will be stoked when the teams meet in Cincinnati on Sunday. The last time these teams met at the home of the Bengals it finished in a 37-37 tie, and entering Week 9 in 2022 that remains the highest-scoring tie in an NFL game since the NFL and AFL merged in 1970.

The New England Patriots are 4-4 for the fifth time in the Bill Belichick era (since 2000) as they approach a home game against the Indianapolis Colts (3-4-1). The other four times the Patriots started 4-4 under Belichick, they made the playoffs three times (2001, 2005, 2021) and missed the playoffs once (2002). Between the regular season and playoffs, Belichick owns an 18-9 career record against the Colts, with only Don Shula (36 wins as coach of the Dolphins from 1970 to 1995) having achieved more such wins.

Tom Brady says he is out to "do the best you can do" following a trying season for the Tampa Bay Buccaneers quarterback, ahead of this weekend's clash with the Los Angeles Rams.

The veteran seven-time Super Bowl winner, who originally called time on his career at the end of last season before reversing his decision, has endured a tough time on and off the field in recent months.

Brady has seen the Bucs fall to 3-5 following defeat to the Baltimore Ravens, while the 45-year-old has also been finalising his divorce from Gisele Bundchen over the past week.

But speaking ahead of Sunday's encounter with incumbent Super Bowl champions the Rams at Raymond James Stadium, he says he is focused on ensuring he is the strongest possible version of himself in all walks of life.

"I've always tried to do the best I could do here [at the Bucs' facility], and then when I leave here, I try to do the best I can do," he stated. "That's what we all try to do.

"I'm sure everyone sitting in this room, everyone sitting at home, is trying to wake up every day doing the best they could do for their families and their career.

"I'm no different. So just do the best you can do every day. We certainly try to do."

Brady is hoping the Bucs can gain revenge against the Rams, with the quarterback having gone 0-3 against them over the last two years, including an NFC divisional round exit last campaign.

He does not expect an easy campaign over the coming weeks, but insists the team do not want sympathy, adding: "It's not like it gets easier; it's not like it gets any less competitive.

"No one feels sorry for us, nor should they. They're trying to win those games. We're trying to win, and we just haven't done a good job the last six weeks doing that."

The Buffalo Bills would be "crazy" to rule out a move for free agent Odell Beckham Jr., says general manager Brandon Beane.

Beckham Jr.'s future has been the subject of speculation, with the wide receiver still without a franchise after suffering a torn anterior cruciate ligament in the Los Angeles Rams' victory over the Cincinnati Bengals in Super Bowl LVI.

The 29-year-old looks unlikely to sign for the Rams after he hit out at the franchise for offering him the "lowest of low" contracts last month, and Buffalo has been touted as an alternative destination.

Beane believes the opportunity to sign the three-time Pro Bowler upon his return to fitness would certainly be worthy of closer examination.

"OBJ's a heck of a talent," Beane told reporters on Wednesday. "You know where he was drafted, obviously he had the great catch and he might have been the MVP of that Super Bowl, does he not tear the ACL. 

"He's a heck of a player, everyone in this room knows who OBJ is. You know me, if we think he can help this team, we'd be crazy not to at least look into it."

The Bills moved to 6-1 for the season with an impressive 27-17 win against the Green Bay Packers on Sunday.

Beckham Jr. was clearly impressed by Buffalo's performance in that game, tweeting "damn Buffalo" alongside a saluting emoji after they raced to a 24-7 half-time advantage, adding further fuel to speculation he could join the AFC East leaders.

It's fair to say that, eight weeks into the 2022 NFL season, it has been a year of surprises.

The New York Giants have six wins, the Seattle Seahawks lead the NFC West and two preseason NFC favourites, the Tampa Bay Buccaneers and Green Bay Packers, have collapsed to 3-5 starts.

This is a campaign in which to expect the unexpected and, as such, three of the top quarterback displays from Week 8 heading into Monday Night Football are entirely in keeping with the theme of 2022.

While one star still shaking the rust off following an injury lay-off delivered the kind of game most have come to anticipate from him, the degree of accuracy displayed by the trio of signal-callers surrounding him at the top of Stats Perform's well-thrown rate chart by the end of Sunday's action was eyebrow-raising to say the least.

And there was one quarterback who tried and failed to find a new team in the offseason who rose above the rest. 

Jimmy G's perfect day

There will never be a game that definitively decides the endless Jimmy Garoppolo debate in the Bay Area, where the San Francisco 49ers' quarterback who was meant to be elsewhere this season remains a beloved but polarising figure.

But nobody could argue Garoppolo was not excellent in Week 8 as the 49ers scored 24 unanswered points to sweep the Los Angeles Rams with an emphatic 31-14 win at SoFi Stadium.

So much of the attention in the immediate aftermath was rightly on Christian McCaffrey, who became the fourth player with a touchdown pass, rushing touchdown and touchdown reception in a single game since the 1970 merger in a remarkable performance just 10 days on from his trade from the Carolina Panthers.

However, Garoppolo also deserves a share of the spotlight following what was, by at least one measure, a perfect game from a quarterback frequently criticised for his volatility.

Garoppolo ended the defeat of the Rams with a 100 per cent well-thrown rate. Each of his 25 passes, excluding throwaways, was deemed to be accurate and well-thrown.

He is the 35th player to achieve such a feat and the second this season following Trevor Lawrence for the Jacksonville Jaguars in Week 2 against the Indianapolis Colts.

While Garoppolo averaged only 6.76 yards per attempt, he still completed a host of big-time throws, including a third-down touchdown shot to a leaping McCaffrey and a 56-yard bomb down the left sideline to Ross Dwelley that was followed by a perfectly placed ball to George Kittle in the back of the endzone on a sprint out pass that iced the game.

At 4-4 heading into the bye with a star-studded offense and a series of players still to return from injury on defense, the 49ers are ideally positioned for a surge down the stretch. They won't get perfect every game from Garoppolo, but if he maintains a level close to what he produced in Inglewood on Sunday, San Francisco will be a major threat in the NFC.

Air Marcus has Falcons on top

Marcus Mariota had hardly been trusted to throw the ball over the four games prior to Atlanta's wild win over the Carolina Panthers by head coach Arthur Smith.

Only once over those four games had he registered more than 20 passing attempts, but Mariota was allowed to air it out on Sunday, and the Falcons should be delighted by the manner in which he did so.

The former second overall pick delivered an accurate well-thrown ball on 92.6 per cent of his 27 pass attempts, maintaining remarkable accuracy while pushing the ball down field with consistency in a captivating shoot-out.

Mariota averaged 10.15 air yards per attempt against Carolina. Just five quarterbacks – Josh Allen (12.96), P.J. Walker (12.33), Tua Tagovailoa (11.79), Russell Wilson (11.04) and Jalen Hurts (11.04) – were more aggressive in that respect.

Of that quintet, Tagovailoa (82.4 per cent) and Wilson (84.6 per cent) were the only two signal-callers to even post a well-thrown rate of 80 per cent.

Mariota blended accuracy and deep-ball aggression in a way most quarterbacks struggle to replicate and, though he tossed an overtime interception that should have cost the Falcons the game, his performance may convince Smith to diversify his approach and shift to a more balanced attack as the 4-4 Falcons look to make a surprise run at the NFC South title.

Dak looks all the way back

The case could be made that the Cowboys were still running the 'Cooper Rush' offense in Prescott's first game back from a finger injury in Week 7 against the Detroit Lions.

Dallas laboured somewhat in that one before pulling away and, though the Week 8 performance was not a faultless one from Prescott, it was one to breed hope the Cowboys can legitimately contend to go deep into the NFC playoffs with him at the helm of the attack.

Prescott posted a well-thrown rate of 92.3 per cent in the Cowboys' 49-29 win over the Chicago Bears, with arguably his most aesthetically pleasing throw coming on his first touchdown pass as he split safeties Eddie Jackson and Jaquan Brisker on a 21-yard rope to CeeDee Lamb on third-and-nine.

Third down did not prove a challenge for Prescott at any point. He completed five of his six third-down throws for 85 yards and a touchdown, with a Bears defense ill-equipped to stop the Cowboys consistently frustrated when they got into positions to get off the field. 

An interception by Jackson was the sole blemish on the day for Prescott, who also had a rushing touchdown, and the room for improvement he clearly still has after a showing of this calibre should be of great excitement to the 6-2 Cowboys as they attack the second half of the season.

Fields fills Chicago with hope 

The Bears did not produce the all-round performance to keep pace with the Cowboys, but it was another effort by last year's first-round pick Justin Fields to boost optimism around his prospects of blossoming into one of the league's better quarterbacks.

After finally building a gameplan around his athleticism in the Monday Night Football win over the New England Patriots, the Bears once again leant on Fields' mobility. He threw seven times on the move, with Chicago also implementing play-action and the quarterback bootleg into the attack.

The results were impressive as Fields finished the game with a well-thrown rate of 90.9 per cent while averaging 9.5 air yards per attempt. On top of that, he did not throw a single interceptable pass, though he did have one pick called back because of a roughing the passer penalty.

Fields was perfect on play-action, with all six of his passes from those concepts well thrown, and he would have had significantly more than 151 passing yards to his name had rookie receiver Velus Jones not dropped an outstandingly placed moonball down the right sideline from the Chicago 47-yard line in the second quarter.

But Fields still accounted for three touchdowns, throwing two and rushing for another in a 60-yard display on the ground. Though the Bears' decision to trade defensive stars Robert Quinn and Roquan Smith will play a role in limiting their wins in 2022, the Bears will be increasingly convinced Fields is the right man to rebuild the team around if he continues in this vein of form.

Cooper Kupp is hopeful he dodged "a bullet" with the right ankle injury he sustained late in the Los Angeles Rams' defeat to the San Francisco 49ers on Sunday.

The wide receiver was taped up during the postgame news conference, having looked to have rolled his ankle in the fourth quarter of his side's 14-31 loss, sparking fears of a potential lay-off.

But Kupp is optimistic he has not done serious damage as he waits to discover the extent of his injury.

"It just got rolled up a little bit," he said. "[My] foot got caught, but I think it was able to slide out of there before there was too much damage done.

"So, we'll see over these next few days how it responds. Right now, things are pointing towards dodging a bullet."

Rams head coach Sean McVay felt he should not have put Kupp - who made eight catches and scored a touchdown - in the position to suffer the injury in the first place.

The 29-year-old has no issue with his boss, stressing that such an injury is simply the nature of the game.

"Beyond just the coach that he is, he cares about his guys and about his players, and so I know he feels bad about that," he added.

"But at the end of the day you're playing a football game. So I obviously don't hold anything against him in that regard.

"It's a violent random game, and you play it as hard as you possibly can until the fourth quarter hits zero. And I can respect that and appreciate that."

Christian McCaffrey declared he was "proud to be a 49er" after his rare touchdown hat-trick inspired San Francisco's 31-14 win over the Los Angeles Rams.

Playing in only his second game for the Niners following his blockbuster trade from the Carolina Panthers, McCaffrey made a huge impact at SoFi Stadium on Sunday.

The star running back ran for a touchdown, took a pass from Jimmy Garoppolo to score another and also picked out Brandon Aiyuk with a 34-yard pass for a rare treble.

McCaffrey is the first NFL player since LaDainian Tomlinson in 2005 to achieve a touchdown trifecta feat.

He racked up 94 rushing yards and 55 receiving yards, as well as turning provider for wide receiver Aiyuk.

The 49ers stormed back in the second half to move to 4-4 ahead of their bye week and McCaffrey says the victory was more important than personal achievements. 

"Obviously, those things are really cool," McCaffrey said. "I think the biggest thing is coming out with a win and playing a second half like that, too. ... But I'm just proud to be a 49er and it felt good to get a win today."

Niners head coach Kyle Shanahan knows he is fortune to have McCaffrey after they got back on track despite being without Deebo Samuel.

"I think everyone knows how good of a player he is, but I just like how consistent he is and under control in what he does," Shanahan said.

"He's a very smart player, and he makes a lot of plays and stuff, but it's the consistency of how he plays his game. I feel like he was a great guy to add for us."

A win for the Niners leaves them second in the NFC West ahead of the 3-4 Rams.

Christian McCaffrey accomplished a feat not seen in 17 years as he delivered a starring performance in the San Francisco 49ers' 31-14 road win against the Los Angeles Rams on Sunday.

After being acquired in a trade from the Carolina Panthers less than two weeks ago, McCaffrey showed exactly why he is considered arguably the best running back of his generation.

Against the reigning champions, he became the first player since LaDainian Tomlinson in 2005 to score a rushing, receiving and passing touchdown in the same game.

His first score came through a trick play in the second quarter, as what appeared to be a regulation toss play to the right-hand side turned into a halfback pass as McCaffrey dialled up a 34-yard rainbow pass to Brandon Aiyuk in the end zone.

Rams quarterback Matthew Stafford had his side leading 14-10 at half-time after a one-yard quarterback sneak for a touchdown and a 16-yard toss to Cooper Kupp, but McCaffrey put the 49ers ahead with a nine-yard touchdown catch late in the third period.

It was followed by a quick Rams punt, before McCaffrey put the exclamation point on his day by punching in a one-yard touchdown to begin the fourth quarter.

The 49ers offense fired on all cylinders, with quarterback Jimmy Garoppolo completing 21 of his 25 passes for two touchdowns and no turnovers, as Aiyuk and George Kittle also caught touchdown passes.

McCaffrey finished with 18 carries for 94 yards on the ground, eight catches for 55 yards through the air, and completed his only pass attempt for 34 yards.

King Henry continues to own the Texans

Tennessee Titans workhorse Derrick Henry was unstoppable against the Houston Texans, carrying the ball 32 times for 219 yards and two touchdowns in a grinding 17-10 win.

Incredibly, it is the fourth consecutive matchup against the Texans where Henry has posted at least 200 yards and two touchdowns, and the sixth total time of his career against all teams. No other player in the history of the league has more than three career games of at least 200 yards and multiple touchdowns.

With his second touchdown, Henry – who had such a significant workload due to rookie quarterback Malik Willis making his debut start in place of the injured Ryan Tannehill – broke the Titans' career touchdown record with his 75th.

San Francisco 49ers wide receiver Deebo Samuel will miss Sunday’s game against NFC West rivals the Los Angeles Rams with a hamstring injury.

Samuel, a first team All-Pro selection in 2021, was injured in the 49ers’ 44-23 loss to the Kansas City Chiefs last week. The dynamic playmaker played through the issue during the game, but did not practice at all this week.

Niners head coach Kyle Shanahan on Friday said he is hopeful Samuel can return for San Francisco’s November 13 game against the Los Angeles Chargers following a Week 9 bye.

"He's not good enough to go," Shanahan said. "The fact that he even had a chance hopefully means he'll be good with the week off and be ready for the next game."

Samuel has compiled 387 receiving yards and two touchdowns on 32 catches so far this season, while adding 138 rushing yards and a touchdown on 24 attempts.

His best performance in 2022 came against the Rams in Week 4, when the fourth-year pro had six receptions for 115 yards and contributed a 57-yard touchdown catch to the 49ers' 24-9 victory.

Including the 2021 NFC Championship Game, Samuel has amassed 621 yards from scrimmage with five total touchdowns in five meetings with the Rams dating back to Week 12 of the 2020 campaign. The 49ers won all four of the regular-season matchups between the teams during that stretch.

Shanahan added that fellow wide receiver Jauan Jennings will be listed as questionable for Sunday’s game due to a hamstring injury of his own.

Jennings ranks fourth among San Francisco players with 14 catches and 180 receiving yards in seven games this season.

The San Francisco 49ers are looking to continue their regular-season dominance over the Los Angeles Rams, and may need to lean on new running back Christian McCaffrey to help them do so.

San Francisco's trip to SoFi Stadium marks a critical game for these NFC West rivals, who have both struggled to produce their best this season.

After a bye week, the defending Super Bowl champion Rams are 3-3, while the 49ers are coming off back-to-back losses, which have dropped them to 3-4.

However, the 49ers have plenty of reason for confidence of getting back on track before their bye week against an opponent they defeated 24-9 in Week 4.

That victory made it seven straight regular-season wins over the Rams for the Niners, their second-longest streak against Los Angeles all-time (17 straight from December 1990 – December 1998).

But the 49ers will not have happy memories from their previous visit to Los Angeles, the Rams having prevailed 20-17 in last season's NFC Championship Game to book their place in the Super Bowl.

Wide receiver Deebo Samuel played a critical role in that game and has been a key feature in the 49ers' success against the Rams. 

Samuel has accounted for seven regular-season touchdowns in his career against the Rams (three receiving, three rushing, one passing) but will be unavailable for San Francisco this weekend due to a hamstring injury.

The loss of the best running wide receiver in the NFL may see greater onus placed on arguably the best receiving running back, with McCaffrey sure to be an integral part of the gameplan after the 49ers traded four draft picks to acquire him from the Carolina Panthers.

McCaffrey averaged 6.2 yards on his 10 touches in his debut against the Kansas City Chiefs and, though the 49ers will look for him to boost a run game that has a disappointing success rate of 33.7 per cent through seven weeks, the absence of Samuel and their underwhelming ground game could see San Francisco feature the former Panther heavily in the passing game.

San Francisco's 44-23 loss to the Chiefs last week marked the first time they have lost back-to-back games by at least 14 points since Weeks 9-10, 2020. They followed those games up with a 23-20 win against the Rams in Los Angeles.

The 49ers will look for a defensive upturn after their struggles against Kansas City, though defensive coordinator DeMeco Ryans' group is still battling injuries in the front seven.

Holding the Rams in check will be critical to San Francisco's hopes of overcoming their absences. Los Angeles have scored at least 20 points in all three of their wins this season and 10 or fewer points in all three losses. 

Rams quarterback Matthew Stafford's record against the 49ers should also offer optimism to Kyle Shanahan's team. Stafford is 1-6 in his regular-season career against the 49ers, his worst record against any NFC opponent.

Stafford has thrown four touchdown passes and five interceptions in his three games against them since joining the Rams, losing each one. Whether he improves on Sunday is likely to have a huge say in which teams emerge from the NFC West.

The big boys are back in Week 8 as the NFL season edges its way closer to the playoffs.

The Philadelphia Eagles, Buffalo Bills and Minnesota Vikings all return after a bye week, as do the defending champion Los Angeles Rams, who will look to increase the pressure on the San Francisco 49ers.

The Eagles are aiming to maintain their 100 per cent record when the Pittsburgh Steelers come to town, while the Bills host Aaron Rodgers and his wobbling Green Bay Packers.

Stats Perform has taken a look at the numbers ahead of Sunday's games, starting in the city of brotherly love.

Pittsburgh Steelers (2-5) @ Philadelphia Eagles (6-0)

It promises to be a tricky trip for Pittsburgh, as the Eagles own a nine-game winning streak at home against them, a streak that started in 1966 (Pittsburgh's last win there was Week 6, 1965). It is the Eagles' longest home winning streak against a single opponent in franchise history.

The Steelers lost 16-10 at the Miami Dolphins last week, and are averaging just 15.3 points per game, the second fewest in the NFL (Denver Broncos, 14.3). The last time they finished in the bottom two of the NFL in scoring was 1969 (15.6 points per game, second worst).

The Eagles have held a lead of at least 14 points in each of their six games this season. The last team to do so in seven straight games to begin the season was the 2007 Patriots (eight straight).

Philadelphia have won Jalen Hurts' last nine starts, tied for the longest quarterback win streak in franchise history with Carson Wentz (2017), Donovan McNabb (2003) and Norm Van Brocklin (1960). The Eagles were 6-10 in Hurts' first 16 career starts in the NFL.

San Francisco 49ers (3-4) @ Los Angeles Rams (3-3)

Including a 24-9 home win in Week 4, the 49ers have won seven straight regular-season games against Los Angeles, their second-longest streak against the Rams all-time (17 straight from December 1990 to December 1998). However, the Rams beat the 49ers in last season's NFC Championship Game at SoFi Stadium.

San Francisco lost to the Kansas City Chiefs, 44-23, at home last week. It was the first time they have lost back-to-back games by at least 14 points since Weeks 9-10 in 2020. They followed those games up with a 23-20 win against the Rams in Los Angeles.

Last week, Jimmy Garoppolo threw for 303 yards, the 11th game in his career with at least 300 yards. The 49ers won the first seven of those games but are just 1-3 in the last four. The only win in that span came on the road against the Rams in Week 18 last season.

Rams QB Matthew Stafford is 1-6 in his regular season career against the 49ers, his worst record against any NFC opponent. He has thrown four touchdown passes and five interceptions in his three games against them since joining the Rams, losing each one.

Green Bay Packers (3-4) @ Buffalo Bills (5-1)

The Packers have won their last four home games against the Bills, but are 0-6 all-time in Buffalo, most recently losing a 21-13 game there in Week 15, 2014. The Bills are the only active franchise the Packers have never beaten on the road.

Green Bay lost 23-21 to the Washington Commanders last week, and have lost three straight games for the first time since Weeks 11-13 in 2018. They have not lost four straight since Weeks 8-11 in 2016. The last time they lost four of their first seven games was in 2006 (also 3-4).

The Bills are coming off their bye week following a 24-20 win in Kansas City in Week 6. Since the Bills' last Super Bowl appearance in 1993, they have begun a season 5-1 four times – 1995, 2008, 2019, and this year.

Buffalo's offense has faced a blitz on 35.3 per cent of its passing plays this season, the fourth highest in the league. The Packers have faced a blitz just 20.2 per cent of the time, second lowest in the league (Miami, 18.2). The Bills have blitzed opponents just 12.9 per cent of the time, the lowest in the league.

Elsewhere…

Dak Prescott should face the Chicago Bears (3-4) after making his return in the Dallas Cowboys' (5-2) win over the Detroit Lions last week, moving his career record as a starter to 54-33 (.621). Since 2016. The Cowboys are 9-8 when Prescott does not start (.530) while averaging almost 60 total yards fewer per game when he is not the starter (382.3 with, 322.9 without).

The New York Jets (5-2) enter their clash with the New England Patriots (3-4) with a chance to break their current 12-game losing streak against them, which dates back to the 2016 season. With a loss, the streak would match Denver's 13-game losing streak to Kansas City as the longest active one in the NFL.

Saquon Barkley (110 rushing yards) and Daniel Jones (107) each ran for over 100 yards last week, the third time a New York Giants (6-1) duo has eclipsed that mark. Brandon Jacobs and Ahmad Bradshaw did so in Week 14, 2010 and Week 16, 2007. The only other team with such a duo this season was the New Orleans Saints in Week 5 against the Giants' opponents for Week 8, the Seattle Seahawks (4-3).

The Tennessee Titans (4-2) own a four-game win streak after a 19-10 win at home against the Indianapolis Colts. This is the Titans' sixth-straight season with a winning streak of at least four games, and it could go to five with a win at the Houston Texans (1-4-1).

Los Angeles Rams defensive tackle Aaron Donald cut his ties with brand management agency Donda Sports amid further condemnation for its owner Kanye West.

The three-time NFL Defensive Player of the Year signed with the company following victory at Super Bowl LVI in February, alongside Boston Celtics swingman Jaylen Brown.

But both men have now left the organisation amid further derogatory and antisemitic comments by its musician and businessmen founder, who is now known as Ye.

"We felt a responsibility to send a clear message that hateful words and actions have consequences and that we must do better as human beings," Donald said via a statement issued alongside his wife Erica.

"We do not feel our beliefs, voices and actions belong anywhere near a space that misrepresents and oppresses people of any background, ethnicity or race."

Ye saw his ties severed with apparel giant Adidas on Tuesday, having held a near-decade-long lucrative sportswear partnership with the German brand.

Carolina Panthers interim coach Steve Wilks says "no one is bigger than the team" after he kicked Robbie Anderson out mid-game in their 24-10 loss to the Los Angeles Rams on Sunday.

The Panthers wide receiver was seen in a heated argument with position coach Joe Dailey late in the first half, before resuming their verbal exchange midway through the third quarter. Anderson had been benched for the third quarter and had been sitting alone on a cooler, before the second argument.

Wilks, who was taking charge for the first time after Matt Rhule was fired in midweek, intervened and sent Anderson to the locker room.

"No one is bigger than the team," Wilks told reporters. "I'm not going to focus and put a lot of attention on one individual… I'm not putting a lot of energy into one individual."

Anderson has been linked with a trade away from Carolina and Wilks said when asked about the 29-year-old's future: "Right now everybody is being evaluated, as well as myself.

"We've got to figure out what's going to be right chemistry to put out on the field, offensively and defensively."

Anderson proactively spoke to reporters after the game, stating he was "honestly confused" by the situation.

"I wanted to be in the game. I've never had somebody yell to get out of the game," Anderson said.

"I was honestly confused and upset by that. I should be. I don't see nobody that is a true competitor, that knows the value they bring and has true passion for the game, that will be okay with being told not to do something or being taken out of something when they didn't do nothing wrong."

Anderson failed to have a catch in Sunday's game, having entered the game with 13 receptions for 206 yards.

The former New York Jets receiver had signed a two-year $29.5 million extension through 2023 prior to last season, but only had 53 receptions for 519 yards in 2021.

"I wouldn't say I want to be traded," Anderson said. "I'm going to let God follow his plans for my life. I'll let things take his course on his time.

"I've been in trade rumours before. It's part of the game. I don't let it affect me."

The Buffalo Bills claimed a statement win as John Allen threw three touchdown passes as they improved to 5-1 with a 24-20 victory over the Kansas City Chiefs on Sunday.

Allen, who completed 27 of 40 attempts for 329 yards with no interceptions, found Dawson Knox for the game-winning touchdown with 1:04 left in the fourth quarter at Arrowhead Stadium.

The Bills sealed the win when Von Miller broke a double team to apply pressure on Chiefs QB Patrick Mahomes whose pass for Skyy Moore was picked by cornerback Taron Johnson with 0:41 remaining.

It ended a seesawing contest that had four lead changes, was tied at every change and was within one score throughout, with the AFC East-leading Bills moving ahead of the AFC West-leading Chiefs who fall to 4-2.

Mahomes made 25 of 40 attempts for 338 yards with two touchdowns and two interceptions, with Bills rookie Kaiir Elam picking off a redzone pass in the first quarter. Chiefs wide receiver Travis Kelce made franchise history by reaching the record for consecutive games with a reception (132), finishing with eight receptions for 108 yards but no TDs.

JuJu Smith-Schuster, who had five receptions for 113 yards, spun past two defenders after receiving a Mahomes pass for the opening TD, before Allen found Gabe Davis to reply before half-time, with Harrison Butker's franchise-record 62-yard field goal tying it up at half-time.

Stefon Diggs, who had 10 receptions for 148 yards, added his sixth receiving touchdown this season when Allen found him for 17-yard score but the Chiefs responded again as Mahomes punched a pass to Mecole Hardman.

Butker put the Chiefs up 20-17 in the fourth quarter, but Allen found Knox in the endzone to flip the script.

Rams respond as Anderson thrown out by Panthers

The Los Angeles Rams ground their way to a 24-10 victory over the Carolina Panthers to snap their two-game skid and move to 3-3.

Scores were locked at 10-10 with 16 seconds remaining in the third quarter when wide receiver Ben Skowronek swept down the outside and into the endzone for his career-first TD.

Matthew Stafford shook off the Rams' offensive issues to complete 26 of 33 passes for 253 yards and one touchdown for Allen Robinson, while Darrell Henderson rushed a fourth-quarter TD to pad the win.

Amid the Panthers' own offensive struggles, interim coach Steve Wilks threw Robbie Anderson out of the game after a heated argument with position coach Joe Dailey.