Dan Lydiate has been recalled to the Wales squad for the Six Nations but there is no place for Rhys Webb.
Back-row Lydiate last played for his country against Australia in 2018, but the 33-year-old is among the 36 players selected by head coach Wayne Pivac.
Scrum-half Webb has been overlooked, with Gareth Davies, Tomos Williams and Kieran Hardy getting the nod.
Scarlets back-row Josh Macleod is the only uncapped player in the squad for a tournament Wales will start with an encounter against Ireland at the Principality Stadium on February 7.
Pivac revealed he was unable to pick Rhys Priestland, despite the fly-half being set to return to his homeland with Cardiff Blues next season, due to the 60-cap rule.
Captain Alun Wyn Jones is hopeful of being fit to face Ireland in Dublin as he continues his recovery from a knee injury.
Ross Moriarty, Gareth Anscombe, Rhys Patchell and Scott Williams are among the players ruled out due to injury.
Pivac said: "We are hugely looking forward to meeting up as a squad on Monday and to the forthcoming campaign. The Guinness Six Nations is an important tournament and we have selected a squad accordingly.
"As we consistently spoke about, the autumn for us was about opportunity and development, looking ahead to RWC 2023 and it served that purpose for us.
"This campaign is different, it is tournament rugby and we are excited to get going and to play our part. We have picked a squad for this tournament based on form and we are excited to meet up on Monday and to get our preparation underway."
Wales squad:
Forwards: Rhys Carre, Wyn Jones, Rhodri Jones, Elliot Dee, Ryan Elias, Ken Owens, Leon Brown, Tomas Francis, Dillon Lewis, Jake Ball, Adam Beard, Alun Wyn Jones (captain), Will Rowlands, Cory Hill, Dan Lydiate, Josh Navidi, Aaron Wainwright, Taulupe Faletau, Josh MacLeod, Justin Tipuric.
Backs: Gareth Davies, Tomos Williams, Kieran Hardy, Dan Biggar, Callum Sheedy, Jarrod Evans, Johnny Williams, Jonathan Davies, Nick Tompkins, Owen Watkin, George North, Josh Adams, Hallam Amos, Louis Rees-Zammit, Leigh Halfpenny, Liam Williams.