England recorded a 29-12 victory to do the double over Canada at the StoneX Stadium.
The visitors had to play over an hour with 14 players after Gabrielle Senft was sent off for a high tackle on Hannah Botterman in the 17th minute.
They trailed 10-0 at that point as Marlie Packer and Ellie Kildunne had scored tries in the opening 13 minutes for England.
Canada made a fight of it despite their numerical disadvantage but further tries from Maud Muir, Amber Reed and Jess Breach secured victory for the Red Roses.
Captain Packer, who touched down during the 50-24 win at Sandy Park last weekend against the same opposition, got the scoring started when she forced the ball over from a dominant driving maul.
Kildunne doubled the hosts’ score after 13 minutes following some good pressing, with a second conversion from Meg Jones unsuccessful.
After Senft’s dismissal, Canada reduced the deficit through a 26th-minute Sara Svoboda try.
But England crossed the whitewash again through Muir on the stroke of half-time, with Jones this time adding the extras to make it 17-5 at the break.
The Red Roses extended their lead further 10 minutes into the second half as Bristol’s Reed found a gap in the Canada defence and pounced over. Jones was again on target with the conversion.
Breach crossed over following a great run from Jones to put England’s victory beyond doubt – moments after replacement scrum-half Lucy Packer limped off.
Canada reduced the deficit through a converted Taylor Perry try late on but the Red Roses comfortably held on.
'It's always personal' – Kolisi says South Africa highly motivated for England clash
South Africa captain Siya Kolisi insists the world champions will not be lacking in motivation for Saturday's clash with England at Twickenham, saying the teams' meetings are "always personal".
The Springboks are aiming to inflict a fifth straight defeat on Steve Borthwick's troubled hosts, who suffered a dramatic 42-37 defeat to Australia last week.
England's most recent meeting with South Africa – in the semi-finals of last year's World Cup – was overshadowed by Tom Curry accusing Bongi Mbonambi of directing a racist slur towards him, an allegation the Springboks hooker denied.
South Africa won that match 16-15 thanks to a late Handre Pollard penalty before beating New Zealand in the final, and Kolisi knows they now have a target on their backs.
"It's always personal. That's just how we prepare ourselves for games," Kolisi said on Friday.
"It's got to be personal. It's another man trying to run through you in-game, it doesn't get more personal than that. So every game for us is personal.
"This one, in Twickenham, is a big game and we know what England have been going through. We've been in their position before.
"We know we've got a target on our back at all times. Every single team that plays against us... we've got to make it as personal as possible because we want to stay where we are."
England have recalled full-back Freddie Steward for the match, after he lost his place to George Furbank during the Six Nations earlier this year.
The 23-year-old is delighted to be back in the fold and is determined to make the most of his opportunity.
"It was one of the hardest things I've had to deal with," Steward told BBC Radio 5 Live. "When you have something for a while and then you lose it, it puts into perspective how important that thing is to you.
"Not having that over the last couple of months has been really challenging. Emotionally, it has been tough, but I've had to use that as fuel to keep pushing and wanting to get better and win that place back.
"It can be a kick in the teeth but you have to use those experiences, and I'm sat here now as a better rugby player and a stronger person."
Steward and Van Poortvleit among England changes for Springboks Test
Freddie Steward and Jack van Poortvliet will return for England on Saturday, with Steve Borthwick making four changes against South Africa.
England were unchanged for their narrow defeats against New Zealand and Australia, but the Leicester pair, who were not included in the squad for either of those matches, come straight in to replace George Furbank and Ben Spencer.
Ollie Sleightholme scored his first international tries in the defeat to Australia and is rewarded with a maiden Test start in place of Immanuel Feyi-Waboso, while Sam Underhill comes in for Tom Curry, with both players missing due to head injuries.
England have lost each of their last four Test matches, their longest such run since losing five straight games in 2018.
"We're excited to challenge ourselves against the world's top-ranked team and back-to-back Rugby World Cup champions," Borthwick said.
"Test matches against South Africa are always thrilling contests, and I'm sure Saturday will be no exception."
Meanwhile, South Africa have made 12 changes to their starting XV from their 32-15 win over Scotland on Sunday.
Captain Siya Kolisi and Pieter-Steph du Toit return in the back row, while Cheslin Kobe is also named in the side.
The world champions have got a more balanced look to their bench this time around though, with coach Rassie Erasmus opting not to name seven forwards among the replacements this time around.
England squad in full:
Freddie Steward, Tommy Freeman, Ollie Lawrence, Henry Slade, Ollie Sleightholme, Marcus Smith, Jack van Poortvliet, Ellis Genge, Jamie George (captain), Will Stuart, Maro Itoje, George Martin, Chandler Cunningham-South, Sam Underhill, Ben Earl.
Replacements: Luke Cowan-Dickie, Fin Baxter, Dan Cole, Nick Isiekwe, Alex Dombrandt, Harry Randall, George Ford, Tom Roebuck.
South Africa squad in full:
Alphelele Fassi, Cheslin Kolbe, Jesse Kriel, Damian De Allende, Kurt-Lee Arendse, Maine Libbok, Grant Williams, Ox Nche, Bongi Mbonambi, Wilco Loux, Eben Etzebeth, RG Snyman, Siya Kolisi (captain), Pieter-Steph Du Toit, Jasper Wiese.
Replacements: Malcolm Marx, Gerhard Steenekamp, Vincent Koch, Elrigh Louw, Kwagga Smith, Cobus Reinach, Handre Pollard, Lukhanyo Am.
Healy in line to equal Ireland cap record versus Argentina
Cian Healy is set to equal Brian O'Driscoll's Ireland cap record when they face New Zealand in Friday's autumn international in Dublin.
The 37-year-old prop has represented his country on 132 occasions and, after being named on the bench, will equal O'Driscoll's mark if introduced versus the Pumas.
Ireland suffered their first home defeat since 2021 last time out, going down by a 23-13 scoreline against New Zealand.
Despite that loss, head coach Andy Farrell has only made one change to Ireland's starting lineup, bringing Robbie Henshaw in at inside centre in place of Bundee Aki.
Argentina also named their team on Wednesday, with vice-captain Pablo Matera, Guido Petti and Matias Moroni replacing Santiago Grondona, Franco Molina and Matias Orlando.
Ireland team: Hugo Keenan; Mack Hansen, Garry Ringrose, Robbie Henshaw, James Lowe; Jack Crowley, Jamison Gibson-Park; Andrew Porter, Ronan Kelleher, Finlay Bealham; Joe McCarthy, James Ryan; Tadhg Beirne, Josh van der Flier, Caelan Doris.
Replacements: Rob Herring, Cian Healy, Thomas Clarkson, Ryan Baird, Peter O'Mahony, Craig Casey, Sam Prendergast, Jamie Osborne.
Argentina team: Juan Cruz Mallia; Rodrigo Isgro, Lucio Cinti, Matias Moroni, Bautista Delguy; Tomas Albornoz, Gonzalo Bertranou; Thomas Gallo, Julian Montoya, Joel Sclavi; Guido Petti, Pedro Rubiolo; Pablo Matera, Juan Martin Gonzalez, Joaquin Oviedo.
Replacements: Ignacio Ruiz, Ignacio Calles, Francisco Gomez Kodela, Franco Molina, Santiago Grondona, Gonzalo Garcia, Santiago Carreras, Justo Piccardo.
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