The Tampa Bay Rays are the only unbeaten team remaining after improving their record to 5-0 with a come-from-behind 10-6 road victory over the Washington Nationals on Tuesday.
Tampa Bay began their season with a three-game series sweep at home against the Detroit Tigers, and they have now won all five of their games by at least four runs.
But it was far from smooth sailing against the Nationals, despite the Rays jumping out to a 3-0 lead in the first inning.
Alex Call brought home two runners for Washington in the bottom of the first with a single, and after Jose Siri put Tampa ahead 4-2 with his solo home run in the second frame, the Nationals began to take over.
Lane Thomas tied the game up in the second with a two-RBI double, and Thomas then gave the Nats their first lead with his next at-bat in the fourth inning with an RBI single in an impressive three-hit, three-RBI showing from the right-fielder.
The Rays did not score from the third inning through the seventh, but Randy Arozarena injected some life back into the visitors with his second RBI double of the contest to cut the Nationals' lead to 6-5 going into the last.
Tampa Bay first baseman Luke Raley tied the contest with a solo home run from the very first pitch of the ninth inning, and just three pitches later the Rays had the lead after Josh Lowe followed suit with his own solo homer.
A single from Taylor Walls and a double from Siri put two more runners on base, setting up Yandy Diaz for the 414-foot, three-run bomb to seal the comeback win.
Alcantara shuts out the Twins
The Minnesota Twins came into Tuesday's action unbeaten, before running into a spectacular showing from reigning NL Cy Young Award winner Sandy Alcantara in a 1-0 Miami Marlins triumph.
Alcantara, who had a shaky start in his season opener against the New York Mets, looked right back to his best against the Twins. He pitched the complete nine innings for only three hits and one walk, while striking out five in his 100 pitches.
The only run of the contest came from a solo home run in the second inning from Miami right-fielder Avisail Garcia, snapping a three-game Marlins losing streak.
Another Riley rocket lifts the Braves
Atlanta Braves slugger Austin Riley hit his second home run in as many days to help lift his side to a 4-1 road win against the St Louis Cardinals.
Despite the loss, all 10 Cardinals players to take an at-bat finished with exactly one hit each, but they could not match the power of the Braves.
Following his monstrous 473-foot blast in the opening inning of Monday's game, Riley again went deep in the first inning, this time taking Steven Matz 410 feet over the left-field wall. Orlando Arcia followed Riley's two-run shot with his own solo home run in the second inning.
In his very first start in the majors, 24-year-old Braves rookie Dylan Dodd collected the win as he made it through five innings while giving up six hits and no walks for one run, striking out three in his 73 pitches.