Ireland will be without Garry Ringrose and Iain Henderson for Saturday's Grand Slam decider against England in the Six Nations after the duo suffered injuries in Sunday's win in Scotland.
Andy Farrell's side are on the brink of a first Grand Slam since 2018 after following up wins over Wales, France and Italy with a 22-7 triumph over Scotland at Murrayfield.
However, Ireland's latest win was marred by a serious-looking head injury sustained by Ringrose, with the centre requiring an oxygen mask as he left the field on a stretcher.
Henderson, meanwhile, will also miss the final game of Ireland's campaign as he undergoes surgery on a forearm fracture, a medical update revealed on Monday.
"Garry Ringrose is doing well today and has returned to Dublin," the update read. "He will take no further part in this year's Championship.
"Iain Henderson is due to undergo surgery today on a fractured forearm sustained in the first half of yesterday's game.
"The uncapped Ross Molony is added to the squad to provide additional second row cover."
Ireland said Dan Sheehan and Ronan Kelleher will be monitored ahead of Saturday's contest at the Aviva Stadium after both men sustained shoulder injuries, with Ulster’s Tom Stewart called up to the squad as cover.
Ireland's victory over Scotland was their seventh in succession in the Six Nations – their joint-best run in the Championship alongside a seven-game winning sequence between 2004 and 2005.
France still retain an outside chance of defending their title, however, and will be hoping to pile the pressure on Ireland with a bonus-point victory over Wales before Farrell's men meet England.
Full Ireland squad:
Forwards: Ryan Baird, Jack Conan, Gavin Coombes, Tadhg Furlong, Caelan Doris, Cian Healy, Rob Herring, Ronan Kelleher, Dave Kilcoyne, Ross Molony, Peter O'Mahony, Tom O'Toole, Andrew Porter, Cian Prendergast, James Ryan, Roman Salanoa, Dan Sheehan, Tom Stewart, Josh van der Flier.
Backs: Bundee Aki, Ross Byrne, Craig Casey, Jack Crowley, Ciaran Frawley, Jamison Gibson Park, Mack Hansen, Robbie Henshaw, Hugo Keenan, Jordan Larmour, James Lowe, Stuart McCloskey, Conor Murray, Jimmy O'Brien, Johnny Sexton, Jacob Stockdale, Nick Timoney, Kieran Treadwell.