The Indianapolis Colts will be without Anthony Richardson for Sunday's visit to the Jacksonville Jaguars.
And it sounds like the rookie quarterback could miss a few more games.
Colts coach Shane Steichen confirmed on Monday that Richardson "will miss some time" with a sprained AC joint in his right throwing shoulder.
Backup quarterback Gardner Minshew will start Sunday against his former team, as the Colts face the Jaguars in a matchup of teams tied atop the AFC South with 3-2 records.
Steichen was unsure how many games Richardson would miss, and he may end up needing surgery. It's possible the team could end up placing him on injured reserve, which would keep him out at least four games.
Richardson has made four starts since the Colts drafted him fourth overall in this year's draft, but the dual-threat QB has only been able to finish one game as injuries have forced him out of the other three.
In Sunday's 23-16 win over the Tennessee Titans, Richardson was hurt with just over 4 1/2 minutes to go in the second quarter when he was tackled by two Titans on a 4-yard run. He took a hit to the left shoulder but appeared to land awkwardly on the right one.
Minshew then replaced Richardson and completed 11-of-14 passes for 155 yards, leading Indianapolis to three scoring drives.
In the Colts' 31-20 victory over the Houston Texans in Week 2 on September 17, Richardson suffered a concussion when he took a hard hit to the head at the end of a 15-yard touchdown run. Minshew came in and threw for 171 yards and a touchdown.
Richardson was unable to clear the NFL's concussion protocol and Minshew led Indianapolis to a 22-19 overtime win over the Baltimore Ravens in Week 3. Richardson returned for last Sunday's overtime loss to the Los Angeles Rams - the first game of his young career he was able to complete.
Richardson also suffered a knee bruise on a hard hit near the goal line in the final minutes of a 31-21 season-opening loss to the Jacksonville Jaguars. Steichen said he could have returned, however, and he was taken out as a precaution.
On the season, he has completed 59.5 per cent of his throws for 577 yards with three touchdowns and one interception for an 87.3 passer rating. He has also rushed for 136 yards with four TDs on the ground.
Minshew has completed 68.7 per cent of his passes for 553 yards with two TDs and no picks for a 95.1 rating.