After a scintillating game between the Minnesota Vikings and New Orleans Saints last week, Tottenham Hotspur Stadium plays host to NFL action again as the New York Giants and Green Bay Packers lock horns.
The Giants travelled across the pond for Sunday's London game beset by injuries at wide receiver in their stuttering offense.
No receiver had 20 or more yards in their 20-12 victory over the Chicago Bears last week.
It was the second time in six games that has happened for New York, the team having had just one such instance over their previous 231 outings, but they still improved to a surprise 3-1 record.
Victory against the Bears came with just 71 passing yards, with the Giants yet to have over 200 passing yards in a game so far this season.
Their gross passing yards total this term stands at 642, the second-lowest tally across the NFL behind only the struggling Bears (471).
Rushing has been the name of the game for the Giants offensively.
They boast the NFL's most net rushing yards (770), the fourth-most average carries per game (33.5) and the second-highest average gain per carry (5.75).
While the Packers are heavy favourites to slow New York’s fast start to the season, the odds of them halting running back Saquon Barkley's renaissance look slim.
No player in the NFL is averaging more yards per game than Barkley's 115.8, while a Packers defense that has traditionally struggled against the run is surrendering 4.97 yards per rush, the 11th-most in the league.
Packers linebacker Rashan Gary will be part of a defense hoping to prevent the Giants' charge after recording two sacks in the 27-24 overtime win against the New England Patriots.
He has at least one sack in all four of Green Bay's contests this season and no Packers player has ever registered a sack in each of the opening five games of a campaign.
In total, the Packers, who also hold a 3-1 record, have 11 sacks this season, five of which have come from Gary himself.
Only six teams have more than Green Bay's sack total and just three NFL players have more than Gary so far in 2022.
Offensively, Aaron Rodgers has already racked up some big gains with the Packers recording 17 passes of 20 or more yards this season, only behind the Detroit Lions (18) and Denver Broncos (21).
The veteran QB had two passing TDs in each of his last three contests, all of which have been victories for Green Bay as they bounced back well from a disappointing opening loss to the Vikings.
Bayer Leverkusen 2-3 Leipzig: Visitors fightback halts unbeaten streak for Alonso's side
Bayer Leverkusen suffered their first defeat in 36 Bundesliga matches, as Leipzig came from behind to stun Xabi Alonso's side 3-2 at BayArena.
Lois Openda struck twice for Marco Rose's, who recovered from 2-0 down to make it two wins from two and move to the summit of the table.
It looked like business as usual for the reigning Bundesliga champions when they scored twice in the last seven minutes of the first half through Jeremie Frimpong and Alejandro Grimaldo.
However, Leipzig replied deep into first-half stoppage time with Kevin Kampl reducing the deficit.
Openda then brought the visitors level in the 57th minute, before a stunning long-range strike completed the turnaround 10 minutes from time, condemning Leverkusen to their first league defeat in 15 months.
Data Debrief: Leverkusen's long streak comes to a shuddering halt
Leipzig became the first side to beat Leverkusen in a Bundesliga match since Bochum achieved the feat a staggering 462 days earlier.
The visitors have begun a Bundesliga season with two wins from two for only the second time, also doing so in 2019-20.
They are also now unbeaten in 13 league matches, their longest such streak since Rose took charge.
As for Leverkusen, their invincible streak is officially history, as is their 29-game unbeaten run on home soil.
'We really let ourselves down' - Coleman slams Everton after late Bournemouth collapse
Seamus Coleman acknowledged Everton "really let ourselves down" and must "look at ourselves in the mirror" following their spectacular late collapse against Bournemouth.
Sean Dyche's side, who were seeking their first points of the season, led 2-0 in the 87th minute at Goodison Park through goals from Michael Keane and Dominic Calvert-Lewin.
However, the hosts were undone by three crosses in the latter stages, with Antoine Semenyo pulling a goal back and Lewis Cook levelling, before Luis Sinisterra completed a sensational turnaround in the sixth minute of stoppage time.
Boos rung around Goodison Park as the Toffees remained pointless and rooted to the foot of the Premier League table, and Coleman echoed the supporters' frustrations.
"We really let ourselves down in front of our fans," the skipper said. "We cannot take our foot off the gas at this level. Unfortunately, we did that.
"We cannot be conceding the goals that we did. We have to look at ourselves in the mirror."
Meanwhile, Dyche bemoaned the lack of responsibility amongst his players, as they became the first side in Premier League history to lose a game after leading by two or more goals in the 87th minute.
"We did so much right until they scored their first goal," the Everton head coach said. "The game should have been out of sight. We conceded one and then threw it away. I can't put my finger on it right now.
"They kept raining it forward and got their reward in the end. They were playing it forward and crossing it into the box, and we didn't deal with it. Simple stuff, but we threw it away. It is the third game we have thrown away this season.
"Everyone was looking at someone else to deal with things and that is when there is trouble. You could see the body language change. You have to see games through, and we have enough experience to do that, but today we didn't."
Bournemouth boss Andoni Iraola added: "It was the worst game we played this season. Everton deserved to win today, but the players kept pushing.
"I always have hope because this team has spirit. We have done it before and had some good comebacks. The spark of the first goal made us believe we could do it again."
Nottingham Forest 1-1 Wolves: Bellegarde beauty earns visitors first point
Wolves earned their first point of the Premier League season following a 1-1 draw with Nottingham Forest.
Chris Wood's towering header was cancelled out by Jean-Ricner Bellegarde's stunning strike as the spoils were shared at the City Ground.
The hosts took the lead in the 10th minute as Wood rose to nod home from Elliot Anderson's corner.
However, the visitors were level just two minutes later in spectacular fashion, with Bellegarde firing a stunning long-range volley into the roof of the net.
Gary O'Neil's side had Sam Johnstone to thank after the break, with the debutant producing a strong hand to deny Wood his second goal of the game.
Matheus Cunha curled a shot just wide while the offside flag denied Wood later on, with Forest unable to snatch victory but extending their unbeaten start to the campaign.
Data Debrief: Wolves end losing streak while Wood matches Collymore
After opening the season with two defeats and eight goals conceded, Wolves stopped the rot with a welcome point against their Midlands rivals, while ending a five-game Premier League losing streak in the process.
Meanwhile, Forest remain unbeaten in their opening three games of a top-flight season for the first time since 1995-96.
Heading his side into the lead, Wood became only the second Forest player to score in both their first two home matches in a Premier League season since Stan Collymore 30 years previously.
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