The New York Jets entered the week with Zach Wilson "possible" to start the season opener, but those hopes have now been dashed.
Coach Robert Saleh announced on Wednesday that the second-year quarterback would be sidelined until Week 4 at the earliest.
On Monday, Saleh said it was possible Wilson would be on the field against the Baltimore Ravens after he threw some passes and tested his right knee during a workout.
Wilson suffered a bone bruise and torn meniscus in the knee while scrambling in the Jets' preseason opener on August 12.
The 23-year-old had successful arthroscopic surgery four days later, and the original diagnosis was he would be out for two to four weeks.
Saleh, however, is now saying Wilson will be out until at least October 2, when his team face the Pittsburgh Steelers.
"We are going to make sure both mind and body are 110 per cent and make sure we do right by him," Saleh told reporters. "And we feel talking to the doctors and everyone, it's going to be that Pittsburgh week.
"After all the information gathering, it's just not worth the risk in terms of getting him out there. There's the knee element, there's the mind element, there's the practice element, there are a whole lot of things other than the knee."
Joe Flacco will feature on Sunday when the Jets host the Ravens. He spent his first 11 NFL seasons with Baltimore and guided the team to a championship in 2012 while being named Super Bowl MVP.
The 37-year-old Flacco is the Ravens' all-time leader in passing yards (38,245) and touchdown throws (212).
"I've been in a bunch of games where guys have played their past teams," Flacco said. "Usually, the emotions are definitely crazy. Guys try to act like they're so cool during the week. I've probably thought about it a tiny bit."