Wales need a victory against France in Paris to reclaim the Six Nations crown, and complete a Grand Slam in the process.
Wayne Pivac's team have enjoyed a sensational turnaround in fortunes this year and last week's 48-7 thrashing of lowly Italy made it four wins from four.
With France subsequently losing to England at Twickenham, Wales will wrap up the title with a win on Saturday, while even a losing bonus point could be enough, though that may still leave the door open for Les Bleus to snatch glory should they win their postponed fixture against Scotland.
England are well out of the race, but their captain Owen Farrell is eyeing up a points landmark when the 2020 champions take on Ireland in Dublin.
Scotland, meanwhile, round off what will ultimately go down as a frustrating campaign against Italy.
We use Opta data to preview the round-five, Super Saturday encounters.
SCOTLAND V ITALY
FORM
Scotland have won their last five Six Nations games against Italy – the previous 10 clashes between the sides had seen them share five wins each.
Italy have lost 52 of 54 away games in the Six Nations, with their only two victories on the road coming in Scotland in 2007 and 2015.
That victory at Murrayfield in 2015 was Italy's last in the competition. Their losing streak now stands at 31 games, and they will pick up the wooden spoon for the 16th time in Six Nations history.
ONES TO WATCH
Scotland have the best tackle success rate (92 per cent) of any side in this year's competition. Hamish Watson leads the way in that regard, completing all 44 of his attempted tackles – he has made 133 consecutive tackles in the tournament without missing one, the second-longest such run in Six Nations history, behind Lionel Nallet's 154 for France.
Italy's Sebastian Negri has made 127 post-contact metres in the 2021 Six Nations, the most of any forward in the championship.
IRELAND V ENGLAND
FORM
England have won their last two meetings with Ireland in the Six Nations and could win three in a row against them for only the second time, after doing so between 2012 and 2014.
Ireland lost to France in their last home game, only once before have they suffered defeat in back-to-back home games in the Six Nations – in 2010 versus Scotland at Croke Park and 2011 versus France at the Aviva Stadium.
Jones' England have won their last four Tests against Ireland, preventing them from scoring any first-half points in their last two meetings and scoring an average of 4.3 tries per game in that run.
ONES TO WATCH
CJ Stander announced his retirement this week, with the 31-year-old set to hang up his boots at the end of the season. This will be his final appearance for Ireland, having won his 50th cap in the 27-24 win over Scotland in round four.
Owen Farrell, son of Ireland coach Andy, is the top scorer in the Six Nations this year (44) and is just six points away from 500 in the championship. Only Ronan O'Gara (557) has reached that milestone exclusively in the Six Nations (since 2000).
FRANCE V WALES
FORM
Wales are bidding to win a sixth Six Nations title (since 2000), only England (seven) have won the championship more often. If they win this match it would be their fifth
Grand Slam – no other side has more than three.
Recent history is on Wales' side heading to the Stade de France. They have won three of their last four away games against Les Bleus in the Six Nations (L1), triumphing in their last trip to Paris (24-19 in 2019) despite trailing by 16 points at half-time – the biggest comeback for a team in the competition.
Indeed, pre-tournament favourites France have won only two of their last nine Six Nations games against Wales (L7) after winning nine of the previous 12 (L3).
ONES TO WATCH
Antoine Dupont already has four try assists in this Six Nations, only five players have ever recorded more in an edition of the championship, with Frederic Michalak
(seven in 2006) the only Frenchman to do so.
Louis Rees-Zammit is the joint top try scorer in the 2021 Six Nations (four, level with England's Anthony Watson). Shane Williams (six in 2008) is the only Welsh player to score more than four in an edition of the tournament.
'Job not done' for Springboks after All Blacks triumph, says Kolisi
South Africa captain Siya Kolisi warned his team the job is far from done despite them rallying for a thrilling victory over New Zealand in the Rugby Championship on Saturday.
The Springboks secured a 31-27 win over the All Blacks at Ellis Park, coming from behind with two late tries from Sacha Feinberg-Mngomezulu and Grant Williams.
The victory hauled South Africa onto 14 points in the Championship standings as they bid to end New Zealand's four-year stranglehold on the title, but Kolisi says there is still work to be done.
Addressing the capacity crowd in his post-match interview, Kolisi said: "We play for a lot but you people are our number one motivation.
"We appreciate you every single day. Please don't stop. When times are tough, please keep supporting us. We cannot do it without you.
"We respect the All Blacks. No matter what people say about them, when they need to turn up, they turn up. We believed in ourselves, we didn't panic, and we did what we wanted.
"They were catching us on the exit. After the first try in the second half, we picked it up. I'm really proud of the boys but the job is not done."
All Blacks captain Scott Barrett, meanwhile, was proud of his team-mates' efforts but admitted they had just fallen short of putting together a complete performance.
"Well done to the Springboks, it showed the class team they are," he said. "We weren't quite good enough. We were good for 62 minutes and it's an 80-minute game.
"There were two key moments after kick-offs where we couldn't quite get out of our half and they punished us. It was a huge effort, we're certainly proud, but it was just not quite to be.
"We'll regroup pretty quickly. Some guys have played here for the first time. It's intense and we'll have to be better next week."
South Africa host New Zealand again in Cape Town next week, while Australia go to Argentina for their round-three matchup.
Bayer Leverkusen 2-3 Leipzig: Visitors fightback halts unbeaten streak for Alonso's side
Bayer Leverkusen suffered their first defeat in 36 Bundesliga matches, as Leipzig came from behind to stun Xabi Alonso's side 3-2 at BayArena.
Lois Openda struck twice for Marco Rose's, who recovered from 2-0 down to make it two wins from two and move to the summit of the table.
It looked like business as usual for the reigning Bundesliga champions when they scored twice in the last seven minutes of the first half through Jeremie Frimpong and Alejandro Grimaldo.
However, Leipzig replied deep into first-half stoppage time with Kevin Kampl reducing the deficit.
Openda then brought the visitors level in the 57th minute, before a stunning long-range strike completed the turnaround 10 minutes from time, condemning Leverkusen to their first league defeat in 15 months.
Data Debrief: Leverkusen's long streak comes to a shuddering halt
Leipzig became the first side to beat Leverkusen in a Bundesliga match since Bochum achieved the feat a staggering 462 days earlier.
The visitors have begun a Bundesliga season with two wins from two for only the second time, also doing so in 2019-20.
They are also now unbeaten in 13 league matches, their longest such streak since Rose took charge.
As for Leverkusen, their invincible streak is officially history, as is their 29-game unbeaten run on home soil.
Record-breaking Root edges England closer to Sri Lanka victory
Joe Root hit a record-breaking century as England edged closer to sealing their series victory over Sri Lanka at Lord's.
Root, who equalled Alastair Cook's record during the first innings of the second Test, made 103 from 111 balls for his 34th Test ton.
England resumed on 25-1 at the start of day three, with Root leading the way for the hosts and the crowd rose as one when a sweeping four completed his landmark century.
He helped his nation set their opponents a target of 483 after they were 251 all out.
As the light faded over Lord's, so too did Sri Lanka's momentum in their record-attempting chase, with Gus Atkinson and Olly Stone claiming Nishan Madushka and Pathum Nissanka respectively.
Play was eventually halted due to bad light, and called off to be resumed on Sunday with the tourists at 53-2 with Dimuth Karunaratne (23) and Prabath Jayasuriya (three) at the crease.
Data Debrief: Root revels on record-breaking day
Day three of the second Test belonged to Root, whose century was also his quickest in Test cricket.
Adding to his 143 in England's first innings, he registered two tons in a match for the first time, while becoming only the fourth player to achieve that feat in a Test at Lord's.
Root also joins Brian Lara and Sachin Tendulkar in scoring 5,000 Test runs in two different decades, while closing the gap on Cook's all-time England tally (12,472) to just 95.
If that was not enough for him, he also took the catches for both of Sri Lanka's wickets, making him the first England player to reach 200 in Test cricket.
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