France resume their bid to win a first Six Nations title since 2010 with a trip to face wounded England at Twickenham, and Wales should made it four wins out of four this weekend.
A coronavirus outbreak in the French camp led to their clash with Scotland being postponed, but they will be back in action against the Red Rose on Saturday a month after beating Ireland.
Wales shattered England's hopes of retaining the title with a 40-24 win at the Principality Stadium and will be expected to stay perfect when they face Italy in Rome, also on Saturday.
Scotland will look to reignite their title challenge when they face Ireland at Murrayfield on Sunday.
We use Opta data to preview the round-four encounters.
ITALY v WALES
FORM
Wales have won their last 15 Tests against Italy, and a 16th would represent their longest ever winning run against a single opponent in Test rugby (they won 15 in a row against France from 1908 to 1927).
A win over England secured Wales' fifth Triple Crown of the Six Nations era, They completed the Grand Slam in each of their previous four Triple Crown-winning campaigns since 2000 (2005, 2008, 2012, 2019).
Italy's losing run in the competition stands at 30 games and they have lost 19 in a row at home, stretching back to a defeat of Ireland eight years ago.
ONES TO WATCH
Azzurri fly-half Paolo Garbisi has made more kicks in play (29) and recorded more kicking metres (1,142m) than any other player in this year's Six Nations.
Josh Adams marked his first match of the tournament by scoring a controversial try against England and the Wales wing will fancy his chances of touching down again in Rome.
ENGLAND v FRANCE
FORM
England have won nine of their 10 home games against France in the Six Nations, including the last seven in a row. Their only defeat came in February 2005, going down 18-17.
France have won seven of their last eight games in the Six Nations and will look for a fourth consecutive victory in the competition this weekend.
Les Bleus have scored the opening try of the game in 15 of their most previous 18 matches in this tournament, including their last eight in a row.
ONES TO WATCH
Wing Anthony Watson will win his 50th cap for England. He has the best average gain per carry rate (10.1 metres) of anyone to make 10 or more carries in the 2021 Six Nations and has also made the most post-contact metres (141).
France lock Paul Willemse has not missed any of his 34 tackles in the Six Nations this year and has made the joint-second most dominant tackles with four, England's Tom Curry (5) the only player to have made more.
SCOTLAND v IRELAND
FORM
Ireland have lost just three of their last 19 games against Scotland in the Six Nations, winning all the rest. Each of the men in green's defeats came by a margin of five points or fewer.
Scotland have lost their last two Test matches at Murrayfield. They have not been beaten in more consecutive games at their traditional home venue since losing four on the bounce between November 2014 and March 2015.
Gregor Townsend's side are the only team to average fewer than 10 missed tackles (8.5) per game in the Six Nations in 2021 and as a result boast the best tackle success rate of 92 per cent.
ONES TO WATCH
Hamish Watson has been an influential performer for Scotland, winning three turnovers and getting through a huge amount of work in the back row.
Ireland back-row Tadhg Beirne has recorded the most ruck arrivals (117) in the tournament, hitting the most rucks of anyone in both attack (87) and defence (30).
Farrell backs 'composed' Prendergast to shine on first Ireland start
Andy Farrell believes Sam Prendergast is ready to step up ahead of his first Ireland start against Fiji at the Aviva Stadium on Saturday.
Farrell has made seven changes to his team, handing first caps to Leinster's Gus McCarthy and Ulster's Cormac Izuchukwu for the penultimate game of the Autumn Nations Series.
The Ireland head coach has handed Prendergast the number 10 jersey for the first time after he was used off the bench in the closing stages of last week's win over Argentina.
Prendergast has only started eight games for Leinster, but Farrell had no hesitation in handing him a first start after he impressed on the Emerging Ireland tour of South Africa.
"I'm confident from what we've seen. We took him on the Emerging [Ireland] and he played in all of those games," said Farrell.
"The aim of that was to grab hold of that team and make sure that he treated it like it was his own, as though he was in charge, and he did that in spades.
"This week we've seen the benefit of that, but we need to see it transfer, obviously.
"Yes, his character is composed, confident but yet not over-confident. He's assertive in what he wants, and he has a nice way about how he goes about his business.”
Farrell also had a glowing review for Izuchukwu, saying: "Izzy has been in and around the squad for a while. The first Emerging Ireland tour was when we first came across his ability, his athleticism, his point of difference.
"That was a couple of years ago but the improvement in his maturity of his game, because he was young in the 15-a-side game when the first tour was on, but the difference between the first and second tour was like chalk and cheese.
"His ability and potential with that maturity, he deserves a shot to show us all what he's got."
On McCarthy, who captained the Ireland Under-20s to a Six Nations Grand Slam in 2023, Farrell said: "He's been a captain and you can see why because his maturity in how he goes about the game."
He added: "We took him on the training week [to Portugal] as a development player and he showed up unbelievably well. He forced our hand to keep him in the squad first and foremost and he deserves a shot to see what he can do as well."
Ciaran Frawley also returns to the bench after missing out last weekend on the back of a poor outing against New Zealand.
And Cian Healy must wait another week for a record-breaking 134th cap - having drawn level with Brian O'Driscoll against Argentina - after the prop was left out of the 23.
Ireland team to play Fiji
Jamie Osborne; Mack Hansen, Robbie Henshaw, Bundee Aki, Jacob Stockdale; Sam Prendergast, Craig Casey; Andrew Porter, Gus McCarthy, Finlay Bealham; Joe McCarthy, Tadhg Beirne; Cormac Izuchukwu, Josh van der Flier, Caelan Doris (capt).
Replacements: Rob Herring, Tom O'Toole, Thomas Clarkson, Iain Henderson, Cian Prendergast, Conor Murray, Ciaran Frawley, Stuart McCloskey.
McKenna fired up for 'biggest game in world football' against Man United
Kieran McKenna believes Ipswich Town's Premier League clash with Manchester United will be the "biggest game in world football" this weekend.
United are in action under new manager Ruben Amorim for the first time since the Portuguese officially replaced Arne Slot as head coach.
While plenty of focus is on the visitors at Portman Road, Ipswich are fired up after beating Tottenham 2-1 before the international break.
That was Ipswich's first league win of the season – and their first in the Premier League in 22 years – and now attention turns to facing United.
McKenna, who previously coached United, said at a fan event this week: "Sunday, what a game. It's one we're really, really looking forward to.
"Not for the personal connection, but as manager of Ipswich Town, to be on that stage, it's what we've worked so hard for.
"It's the biggest game in world football anywhere this weekend, the biggest game in the world in the biggest sport in the world and it's at Portman Road."
Ipswich's surprise win at Tottenham last time out moved them up to 17th, while United are 13th after beating Leicester City 3-0 in Ruud van Nistelrooy's final game in caretaker charge.
Amorim took his first training session on Monday, albeit with many first-team stars away on international duty, and the former Sporting CP boss believes his style of play will be clear to see from the off.
"I think you will see an idea," he told the club's website. "You could like it or not, I don't know, but you will see an idea.
"You will see a positioning. You will see something that we want to reach that kind of level. You will feel that.
"We have to know it's [only] two trainings before the first match. This is the best league in the world. But if I have to say something to you, [it's that] you will see an idea. This I can guarantee."
PLAYERS TO WATCH
Ipswich Town - Liam Delap
Delap scored what proved to be Ipswich's winner against Tottenham and has now netted six of his side's 12 Premier League goals this term.
That makes the Manchester City academy product one of only three players to have scored at least half of his side's goals in the competition this season, along with Erling Haaland at City (55%) and Chris Wood at Nottingham Forest (53%).
Manchester United - Alejandro Garnacho
Garnacho was among the scorers against Leicester two weeks ago and has now been directly involved in 20 Premier League goals for United (13 goals and seven assists).
The Argentina international is one of only two non-British players to reach that figure for United before turning 21, along with Cristiano Ronaldo (25 goals).
MATCH PREDICTION: MANCHESTER UNITED WIN
Ipswich are seeking back-to-back Premier League wins for the first time since February 2022, with that run also beginning with a 2-1 victory against Tottenham.
The Tractor Boys are the only side in the competition without a home win this season. Only five newly promoted clubs have failed to win any of their first six home matches, all of whom went back down.
United have won 17 of their past 19 Premier League games against newly promoted opponents, meanwhile, including nine wins in a row in away fixtures.
The Red Devils were 1-0 winners on their most recent league trip to Portman Road in April 2022, but only once have they won successive league games away to Ipswich.
However, the Tractor Boys have lost four of their past five league matches against Man United, failing to score in each of those losses.
OPTA WIN PROBABILITY
Ipswich Town - 22.2%
Draw - 23%
Manchester United - 54.8%
Slot deserves praise for modest approach to Liverpool job – Mills
Arne Slot deserves praise for not being "arrogant" with his approach to succeeding Jurgen Klopp as Liverpool boss, according to Danny Mills.
The Dutchman has made a hugely positive start to life at Anfield since replacing long-serving Klopp ahead of the 2024-25 season.
The 28 points Slot has collected is the joint-most of any manager in their opening 11 Premier League games along with Guus Hiddink at Chelsea.
Liverpool's only blemish on an otherwise perfect start to the top-flight campaign was a 1-0 loss to Nottingham Forest in September.
Indeed, only in 2019-20 (31 points) have Liverpool collected more points after 11 games of a Premier League season than their 28 this campaign.
Former Leeds United and Manchester City defender Mills has been particularly impressed by Slot's approach to a new era at Anfield.
"Arne Slot has surprised me," Mills told Stats Perform. "They did have a difficult defeat against Nottingham Forest at home. That was a defeat not many people saw that coming, but the start he's had is unbelievable. It's incredible.
"Training might be slightly different, but the style of play is very similar. The players are comfortable with it. They've been high-energy, closing people down, and playing at 100 miles an hour when they win the ball back.
"It shows managerial intelligence to understand the players' qualities and build on what they had when they were successful. He hasn't overthought it or tinkered too much.
"He hasn’t been arrogant and said, 'I'm going to rip it up and start fresh'. It wasn't broken; it was already successful. He's just added to it."
Liverpool won a first ever Premier League title during Klopp's eight-and-a-half years in charge, as well the Champions League in 2018-19.
Klopp also lifted the FA Cup, two EFL Cups, the UEFA Super Cup and FIFA Club World Cup, setting a high benchmark to follow.
"Liverpool identified the man they wanted, brought him in, and he's been very clever," Mills added. "He looked at the squad and thought, 'these are good players. I don't need to change too much'.
"That's smart because Liverpool were very successful under Klopp. If you come in and rip up the playbook and it doesn't work, players will question why they're not doing what worked under Klopp."
Liverpool have conceded just six goals in the Premier League this season – four fewer than next-best Nottingham Forest.
They are conceding at a rate of around 0.5 goals per game, compared to around 1.1 in Klopp's final season in charge (41 goals in 38 matches).
"Slot has tweaked things slightly, maybe made them more defensively solid, which they needed to really challenge," Mills said. "Championship-winning or Champions League-winning teams are built on solid defences.
"You don't win without that. He's shored up the defence and allowed the players to continue doing what they were doing before."
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