Rassie Erasmus says South Africa will "explore any option" to ensure they do not miss out on facing the British and Irish Lions.
The Lions are scheduled to lock horns with the world champions in July and August, but the tour is in doubt due to the coronavirus pandemic.
Playing the series in the United Kingdom has been mooted as a potential alternative to the Lions flying out to South Africa.
Delaying the tour until next year could be another alternative and a decision is expected to be made next month, with talks among the Lions board ongoing.
South Africa's director of rugby Rassie Erasmus, who who coached the Springboks to Rugby World Cup glory in 2019, says the Webb Ellis Cup holders are willing to be flexible over where and when they take on the Lions.
"We desperately want to play the Lions, and we will do anything to play them," he said in a press conference.
"This series only comes around every 12 years. I have heard the different calls and opinions about the tour, and although we didn't play in the Rugby Championship because of player welfare, it was also because we knew there was this big series in 2021.
"If option one of playing in South Africa doesn't work out, we will go to option Z to make it happen.
"We don't want to lose out on the Lions series, we feel we deserve to play against them. I want to, Jacques Nienaber [Springboks head coach] wants to, the players want to. So from our side, we'll do anything.
"But yes, we will explore any option to play the Lions, we will play next year, we will play over there. This is the view from a player and management perspective."
'World-class' Scotland will provide Wallabies' sternest test – Skelton
Australia will face their sternest test to date when they continue their autumn tour against a "world-class" Scotland team at Murrayfield on Sunday.
That is the view of forward Will Skelton, who believes the Wallabies' victories in England and Wales have brought a new energy and confidence to their camp.
Having crashed out in the pool stage at last year's World Cup in France before finishing last in the Rugby Championship, Australia have looked a team reborn in recent weeks.
A first victory at Twickenham since 2015 and a 52-20 rout of Wales – their biggest-ever away win in matches between the teams – have made it an excellent tour to date for Joe Schmidt's side.
But La Rochelle lock Skelton feels their toughest assignment is to come this week, saying: "We've won two games, we're very aware of that.
"The Test against Scotland is going to be the hardest one yet. We're excited about this weekend and we're looking forward to ripping into it.
"Physically they're up there with the top five in the world. I think set-piece wise they're really strong.
"You've got a guy like Finn Russell who's a maestro at the back there. I think it's going be a close one and we'll be up for it.
"There's some class players in the Scottish team and, when they're at it they're world-class, so we're going to have to be on top of our game."
Wales must 'show courage and front up' against South Africa, says Gatland
Warren Gatland has urged Wales to "show real courage and front up" in their final Autumn Nations clash against South Africa.
Gatland's side bring the curtain down on a disappointing year when they welcome the reigning world champions to the Principality Stadium on Saturday.
Wales have lost an unprecedented 11 straight Tests, and could go an entire calendar year without tasting success for the first time since 1937.
Gatland has made four changes from last weekend's 52-20 defeat to Australia, with Sam Costelow, Rio Dyer, Christ Tshiunza and Taine Plumtree all coming into the starting XV.
Gareth Anscombe, Aaron Wainwright and Cameron Winnett drop out of the squad, while Adam Beard misses out through injury.
And Gatland wants his players to demonstrate fighting spirit against the Springboks.
"Last week's result hurts, and we are just as disappointed by it as the fans," he told reporters during his pre-match press conference.
"Our focus now is on training and preparing well for our final game of this Autumn Nations Series.
"There were good elements that we can definitely build on going into Saturday, but we have to improve our accuracy.
"We know what a quality side South Africa are and the physicality they bring. This week, we need to show real courage and front up against the world champions."
'Playing for England is the Mecca' according to Itoje amid global breakaway talk
Maro Itoje has reaffirmed his commitment to England amid talks of a proposed global breakaway league.
Steve Borthwick’s side are looking to end their five-match losing run when they face Japan in their final match of the autumn series on Sunday.
But there is fear that Borthwick could lose many of his players to the new league that reportedly are offering 40 £1m-a-season contracts for marquee players and more periods of rests for the players.
The Rugby Football Union (RFU) only select players for the national team from English clubs, meaning any player joining the breakaway league would jeopardise their Test career.
But Itoje has insisted that playing for England is the pinnacle for him and his teammates.
"I don't really know any of the details of it as yet, but wearing this rose is extremely important to me and my teammates," said Itoje.
"Playing for England is the Mecca."
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