Ciaran Frawley will make his first Test start in Ireland’s Guinness Six Nations clash with Wales after being selected in place of injured full-back Hugo Keenan.
The versatile 26-year-old won his two previous caps as a replacement, including playing the final four minutes of the championship curtain-raiser away to France.
Keenan has been virtually ever-present in his country’s number 15 jersey during the past three years but will miss Saturday’s match in Dublin due to a knee injury suffered in the round-two victory over Italy.
Head coach Andy Farrell, who has included uncapped Munster prop Oli Jager among the replacements, has made seven personnel changes to his starting XV from the 36-0 win over the Azzurri Italy on February 11.
Captain Peter O’Mahony, prop Tadhg Furlong and centre Bundee Aki return following injuries, while lock Tadhg Beirne, scrum-half Jamison Gibson-Park and flanker Josh Van Der Flier are also recalled.
Second-row James Ryan, flanker Ryan Baird, number eight Jack Conan and centre Stuart McCloskey drop to a bench containing a six-two split of forwards and backs.
Prop Finlay Bealham and scrum-half Craig Casey have been left out of the matchday 23 after starting against Italy.
Lock Iain Henderson, who suffered a foot injury playing for Ulster last weekend, is not involved, while centre Garry Ringrose remains absent after missing the opening two rounds with a shoulder issue.
Frawley has been battling Jack Crowley and Harry Byrne for action at fly-half but Farrell has limited back-up options at full-back due to Jimmy O’Brien and Mack Hansen being ruled out of the entire tournament.
The full debutant has played a total of just 44 minutes of international rugby, during cameos in last summer’s World Cup warm-up win over Italy and the 38-17 victory over Les Bleus at the start of the month.
Crowley continues in the number 10 role, partnering Gibson-Park, with Aki and Robbie Henshaw in midfield and Calvin Nash and James Lowe retained on the wings.
In the front row, returning tighthead Furlong will pack down alongside Leinster team-mates Andrew Porter and Dan Sheehan, ahead of the second row pairing of Joe McCarthy and Beirne.
Caelan Doris, who stood in as skipper last time out, reverts from openside flanker to number eight. Van der Flier returns to the number seven role, while O’Mahony is back in at blindside flanker.
Hooker Ronan Kelleher, prop Cian Healy and scrum-half Conor Murray complete the bench.
Ireland are seeking a third successive win in this year’s championship – and an 18th in a row at home – after launching their title defence with back-to-back bonus-point victories over France and Italy.
Opponents Wales began with narrow defeats to Scotland and England and have not won a Six Nations fixture in Dublin since 2012.
Healy in line to equal Ireland cap record versus Argentina
Cian Healy is set to equal Brian O'Driscoll's Ireland cap record when they face New Zealand in Friday's autumn international in Dublin.
The 37-year-old prop has represented his country on 132 occasions and, after being named on the bench, will equal O'Driscoll's mark if introduced versus the Pumas.
Ireland suffered their first home defeat since 2021 last time out, going down by a 23-13 scoreline against New Zealand.
Despite that loss, head coach Andy Farrell has only made one change to Ireland's starting lineup, bringing Robbie Henshaw in at inside centre in place of Bundee Aki.
Argentina also named their team on Wednesday, with vice-captain Pablo Matera, Guido Petti and Matias Moroni replacing Santiago Grondona, Franco Molina and Matias Orlando.
Ireland team: Hugo Keenan; Mack Hansen, Garry Ringrose, Robbie Henshaw, James Lowe; Jack Crowley, Jamison Gibson-Park; Andrew Porter, Ronan Kelleher, Finlay Bealham; Joe McCarthy, James Ryan; Tadhg Beirne, Josh van der Flier, Caelan Doris.
Replacements: Rob Herring, Cian Healy, Thomas Clarkson, Ryan Baird, Peter O'Mahony, Craig Casey, Sam Prendergast, Jamie Osborne.
Argentina team: Juan Cruz Mallia; Rodrigo Isgro, Lucio Cinti, Matias Moroni, Bautista Delguy; Tomas Albornoz, Gonzalo Bertranou; Thomas Gallo, Julian Montoya, Joel Sclavi; Guido Petti, Pedro Rubiolo; Pablo Matera, Juan Martin Gonzalez, Joaquin Oviedo.
Replacements: Ignacio Ruiz, Ignacio Calles, Francisco Gomez Kodela, Franco Molina, Santiago Grondona, Gonzalo Garcia, Santiago Carreras, Justo Piccardo.
Pressure to win for England is a 'privilege', says Wigglesworth
Senior England coach Richard Wigglesworth believes that the pressure to win matches is part of the privilege of playing for the national team.
England face world champions South Africa at the Allianz Stadium on Saturday with displeasure growing after four straight defeats.
Included in that run were narrow losses in their first two Autumn Nations Series games against New Zealand and Australia.
Though England have won three of their last four games against South Africa at Allianz Stadium, Wigglesworth insisted everyone within the squad wants to improve.
"This job of being part of the England team is such a privilege, because so many people care, which makes your feeling on the matter really big," Wigglesworth told BBC Sport.
"Our job is to step back from that and see what was right, what was wrong, and what can we fix.
"We need to see the game for what it is, make the decisions for what they are, and get better every week.
"It is our job to make sure the players understand as much as they can that they can’t get affected by that as well.
"We know the attention the team gets is result-dependent, and rightly so."
The last time England and South Africa faced one another was in the Rugby World Cup semi-final in 2023, in which the Springboks came back from 15-6 down to win 16-15.
England will have to be wise to how the visitors have evolved since that game according to Wigglesworth.
"They have a squad and a plan they have done for a while, and when you are successful you tend to stick to things," he said.
"I have really enjoyed watching what they do, and how they do it. It is our job to meet that and rise to it."
Springboks aiming to have 'two best teams in the world', says Esterhuizen
South Africa centre Andre Esterhuizen said that the Springboks are aiming to have "the two best teams in the world" ahead of their Autumn Nations Series clash against England.
The world champions were pushed all the way by Scotland in their narrow victory at Murrayfield on Sunday, though head coach Rassie Erasmus opted to rotate some key starting positions.
South Africa captain Siya Kolisi and flanker Pieter-Steph du Toit started on the bench, with the changes a common theme during Erasmus' seven-year tenure.
Their opening Autumn Nations Series victory also put them back on top of the world rankings after Ireland's first defeat in 19 home games by New Zealand on Friday.
"One of the good things is that everyone is getting game time now," Esterhuizen told the BBC's Rugby Union Weekly podcast.
"It is also about looking forward, you've got to be able to spare all the guys for the next World Cup and build experience into it.
"The aim is to have the two best teams in the world, all in one squad.
"We want to make it second nature for people slotting in, so if someone steps in, they can just slot in and play the same if not better than the other player."
South Africa next face England, who are yet to pick up a win this autumn, at Twickenham on Saturday.
Steve Borthwick's side suffered a narrow two-point defeat by New Zealand, before conceding an injury-time winning try to Australia on Saturday.
England have now lost each of their last four Test matches, their longest such run since losing five straight games in 2018, but Esterhuizen's former Harlequins team-mate Marcus Smith has been impressive for the Red Roses.
"It's a great space, I obviously love to play there," Esterhuizen added. "It will be great to be running at Marcus, not run off him.
"It's going to be a great match, England have played well in the last few games, it's unfortunate that it hasn't been the results that they want. I think it's going to be a big one."
The Springboks have won three of their last four matches against England (L1), including each of their last two. Three of the last five games between England and South Africa have been decided by single-point margins.
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