Ireland have brought in Rob Herring for injured hooker Dan Sheehan for Saturday's huge Six Nations clash with France, who named an unchanged line-up.
Sheehan started nine of Ireland's past 10 matches, but a hamstring injury sees him drop out for the match at the Aviva Stadium in a possible title and Grand Slam showdown.
Herring will deputise for Sheehan, while Conor Murray has been passed fit to continue his half-back partnership with captain Johnny Sexton, who was himself a fitness doubt.
"It's not nice for Dan," Ireland head coach Andy Farrell said on Thursday. "He's a fantastic player at the top of his game. Anyone would miss a player in that kind of form.
"I sound like a broken record, but it's great because this is exactly what's going to happen down the track in the World Cup.
"International rugby is only going to get bigger and better so it's always going to be about the squad.
"When you get to the World Cup, you've a small squad. There's rightly a 12-day turnaround as far as concussions are concerned, so you're always going to be numbers down."
Jamison Gibson-Park, Tadhg Furlong and Cian Healy all missed Ireland's opening 34-10 win over Wales and remain out of the matchday 23 to face France.
Ireland, who finished second to France in last year's tournament, are ranked number one in the world and have won 21 of their past 22 home games, including each of the past 12.
They host a France side on a 14-match winning run – their best ever streak – most recently overcoming Italy 29-24 in a tight contest last weekend.
Fabien Galthie has stuck with the same XV that started the game in Rome, meaning Romain Ntamack is retained at number 10, despite Matthieu Jalibert's impact from the bench.
Francois Cros returns to the replacements' bench as one of two changes, along with Baptiste Couilloud, with Thomas Lavault and Nolann Le Garrec dropping out.
"Firstly, we have gone with the same personnel due to the performance [against Italy], the victory with a bonus point, which meant they achieved their target," Galthie said.
"Coherence, too, as it is three weeks that we have worked with this group.
"And also confidence because we have confidence in our players who for three years have progressed together; that is why there are no surprises in the starting XV."
France have won each of their past three meetings with Ireland, this after winning just one of their previous nine Test encounters (D2 L6).
'Job not done' for Springboks after All Blacks triumph, says Kolisi
South Africa captain Siya Kolisi warned his team the job is far from done despite them rallying for a thrilling victory over New Zealand in the Rugby Championship on Saturday.
The Springboks secured a 31-27 win over the All Blacks at Ellis Park, coming from behind with two late tries from Sacha Feinberg-Mngomezulu and Grant Williams.
The victory hauled South Africa onto 14 points in the Championship standings as they bid to end New Zealand's four-year stranglehold on the title, but Kolisi says there is still work to be done.
Addressing the capacity crowd in his post-match interview, Kolisi said: "We play for a lot but you people are our number one motivation.
"We appreciate you every single day. Please don't stop. When times are tough, please keep supporting us. We cannot do it without you.
"We respect the All Blacks. No matter what people say about them, when they need to turn up, they turn up. We believed in ourselves, we didn't panic, and we did what we wanted.
"They were catching us on the exit. After the first try in the second half, we picked it up. I'm really proud of the boys but the job is not done."
All Blacks captain Scott Barrett, meanwhile, was proud of his team-mates' efforts but admitted they had just fallen short of putting together a complete performance.
"Well done to the Springboks, it showed the class team they are," he said. "We weren't quite good enough. We were good for 62 minutes and it's an 80-minute game.
"There were two key moments after kick-offs where we couldn't quite get out of our half and they punished us. It was a huge effort, we're certainly proud, but it was just not quite to be.
"We'll regroup pretty quickly. Some guys have played here for the first time. It's intense and we'll have to be better next week."
South Africa host New Zealand again in Cape Town next week, while Australia go to Argentina for their round-three matchup.
Bayer Leverkusen 2-3 Leipzig: Visitors fightback halts unbeaten streak for Alonso's side
Bayer Leverkusen suffered their first defeat in 36 Bundesliga matches, as Leipzig came from behind to stun Xabi Alonso's side 3-2 at BayArena.
Lois Openda struck twice for Marco Rose's, who recovered from 2-0 down to make it two wins from two and move to the summit of the table.
It looked like business as usual for the reigning Bundesliga champions when they scored twice in the last seven minutes of the first half through Jeremie Frimpong and Alejandro Grimaldo.
However, Leipzig replied deep into first-half stoppage time with Kevin Kampl reducing the deficit.
Openda then brought the visitors level in the 57th minute, before a stunning long-range strike completed the turnaround 10 minutes from time, condemning Leverkusen to their first league defeat in 15 months.
Data Debrief: Leverkusen's long streak comes to a shuddering halt
Leipzig became the first side to beat Leverkusen in a Bundesliga match since Bochum achieved the feat a staggering 462 days earlier.
The visitors have begun a Bundesliga season with two wins from two for only the second time, also doing so in 2019-20.
They are also now unbeaten in 13 league matches, their longest such streak since Rose took charge.
As for Leverkusen, their invincible streak is officially history, as is their 29-game unbeaten run on home soil.
'We really let ourselves down' - Coleman slams Everton after late Bournemouth collapse
Seamus Coleman acknowledged Everton "really let ourselves down" and must "look at ourselves in the mirror" following their spectacular late collapse against Bournemouth.
Sean Dyche's side, who were seeking their first points of the season, led 2-0 in the 87th minute at Goodison Park through goals from Michael Keane and Dominic Calvert-Lewin.
However, the hosts were undone by three crosses in the latter stages, with Antoine Semenyo pulling a goal back and Lewis Cook levelling, before Luis Sinisterra completed a sensational turnaround in the sixth minute of stoppage time.
Boos rung around Goodison Park as the Toffees remained pointless and rooted to the foot of the Premier League table, and Coleman echoed the supporters' frustrations.
"We really let ourselves down in front of our fans," the skipper said. "We cannot take our foot off the gas at this level. Unfortunately, we did that.
"We cannot be conceding the goals that we did. We have to look at ourselves in the mirror."
Meanwhile, Dyche bemoaned the lack of responsibility amongst his players, as they became the first side in Premier League history to lose a game after leading by two or more goals in the 87th minute.
"We did so much right until they scored their first goal," the Everton head coach said. "The game should have been out of sight. We conceded one and then threw it away. I can't put my finger on it right now.
"They kept raining it forward and got their reward in the end. They were playing it forward and crossing it into the box, and we didn't deal with it. Simple stuff, but we threw it away. It is the third game we have thrown away this season.
"Everyone was looking at someone else to deal with things and that is when there is trouble. You could see the body language change. You have to see games through, and we have enough experience to do that, but today we didn't."
Bournemouth boss Andoni Iraola added: "It was the worst game we played this season. Everton deserved to win today, but the players kept pushing.
"I always have hope because this team has spirit. We have done it before and had some good comebacks. The spark of the first goal made us believe we could do it again."
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