Katie Boulter will fly the British flag on her own on day six at Wimbledon as she plays Elena Rybakina.
World number one Carlos Alcaraz opens Centre Court for the second successive day as he takes on Chilean Nicolas Jarry.
Elsewhere, last year’s runner-up Ons Jabeur will face former US Open winner Bianca Andreescu and second seed Aryna Sabalenka will be in action.
Here, the PA news agency takes a look at Saturday’s action.
Heavyweights clash earlyIt was just two years ago that Matteo Berrettini made the final at Wimbledon, but injuries have seen him slide down the rankings.
As a result he was not seeded for this tournament and it meant the prospect of a tricky draw.
And having beaten 15th seed Alex De Minaur in the second round, he now squares off with 19th seed Alexander Zverev.
The German, too, is feeling his way back from a serious injury and in days gone by this match-up would not have been out of place in the latter part of the second week.
With Berrettini serving brilliantly against De Minaur and Zverev not traditionally an outstanding performer at SW19, the Italian could send another seed packing.
Match of the dayTwo entertainers will meet on Centre Court as Ons Jabeur takes on Bianca Andreescu in a third-round clash.
Jabeur, last year’s beaten finalist, regularly practises with her Canadian opponent and recently taught her how to play the tweener.
Andreescu is a former US Open champion, but will be playing her third match in three days as she has had to play catch-up with the weather, while Jabeur is well rested after a trouble-free first three matches.
There will be slices, drop shots and possibly tweeners galore as both women eye a place in the second week.
Brit watchAfter a chastening afternoon for the British men on Friday, when Cameron Norrie, Andy Murray and Liam Broady all lost within 90 minutes of each other, Katie Boulter is flying the flag for home players in the singles.
She has one of the toughest tests possible as she plays defending champion Elena Rybakina on Centre Court.
The third seed has not exactly been too convincing in her opening two rounds and Boulter will try and feed off a partisan home crowd as she looks to reach the fourth round for the first time.
Order of play
Centre Court
Carlos Alcaraz v Nicolas Jarry
Ons Jabeur v Bianca Andreescu
Katie Boulter v Elena Rybakina
Court One
Daniil Medvedev v Martin Fucsovics
Aryna Sabalenka v Anna Blinkova
Alexander Zverev v Matteo Berrettini
Hot and humid with the chance of thundery showers.
Alcaraz matches Nadal record as reigning champion scrapes into Madrid Open quarters
Jan-Lennard Struff made life difficult for Carlos Alcaraz, but the reigning Madrid Champion eventually made it through.
Alcaraz had won both of his opening games with the minimum of fuss, but he needed three sets to get beyond Struff, who won a second-set tie-break.
However, Alcaraz eventually prevailed in the decider, clinching a 6-3 6-7 (5-7) 7-6 (7-4) victory.
Alcaraz, who is in the hunt for a third straight title in Madrid, will now face seventh-seed Andrey Rublev for a place in the last four.
Data Debrief: Prodigal son matches the master
There have been plenty of comparisons between Alcaraz and his fellow Spaniard Rafael Nadal.
And with his win on Tuesday, Alcaraz matched Nadal's record for the longest winning run at the Madrid Open, at 14 matches, since the tournament began in 2002.
Sinner fights back to reach first Madrid Open quarter-final
Jannik Sinner has booked his place in the Madrid Open quarter-final, going the distance to beat Karen Khachanov 5-7 6-3 6-3 on Tuesday.
The top seed dropped a set for the first time at the tournament as an in-form Khachanov, but he shook off the concerns of a lingering hip injury to make a comeback.
After winning the second set, he then saved both break points he faced in the decider, finishing off a contest that lasted over two hours.
Sinner has reached the quarter-final of the Madrid Open for the first time and will face either Casper Ruud or Felix Auger-Aliassime next.
Data debrief: Sinner overcomes first big test
Not only has the 22-year-old become the only player to reach the quarter-final at all four Master 1000 events in 2024, but he is the first to achieve that feat since Milos Raonic in 2016.
Sinner has also become the first Italian player to make the quarter-finals of all three existing ATP Masters 1000 events on clay, since 2009 when the Madrid Open took the place of the Hamburg Masters.
Swiatek battles back to reach Madrid Open semi-finals
Iga Swiatek has booked her place in the Madrid Open semi-finals after battling back from a set down to defeat Beatriz Haddad Maia.
The top seed, who made it to the final last year, dropped a set for the first time in this tournament before recovering to win 4-6 6-0 6-2 in a match that lasted just short of two-and-a-half hours.
These two players met in the French Open semi-finals last year and 11th seed Haddad Maia was eyeing an upset when she fought back from 4-1 down to claim the opener.
But Swiatek dropped serve just once in the next two sets as she assumed full control and swept to victory, powered by winning eight straight games from the start of the second set.
Data Debrief: Swiatek statistics up there with the best
Up next for Swiatek will be a last-four clash against either Ons Jabeur or Madison Keys, who play later on Tuesday. That will be her 15th WTA 1000 semi-final appearance since 2020, with no other player having made it to double figures (Aryna Sabalenka and Maria Sakkari are the next best on eight each).
Beating Haddad Maia also means Swiatek has equalled Serena Williams and Maria Sharapova as the fastest player to reach 25 WTA 1000 wins on clay, doing so in just 29 matches.
And Swiatek's emphatic second set saw her tie Coco Gauff for the most number of 6-0 sets won so far this year. They both have seven, just ahead of Sabalenka (five).
Defending champion Sabalenka plays Mirra Andreeva in the last eight on Wednesday after battling past Danielle Collins in three sets. All three of her wins so far have been in deciding sets.
The other last-eight clash is between Elena Rybakina and Yulia Putintseva.
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