Defending men's champion Novak Djokovic and women's world number one Iga Swiatek head the seedings for Wimbledon, which starts on Monday.
The championships issued its lists of seeds on Tuesday, with Russian and Belarusian players absent from the line-up after they were excluded from the tournament because of the ongoing invasion of Ukraine.
It means Russia's men's world number one Daniil Medvedev is absent, while Germany's second-ranked Alexander Zverev also misses out, in his case because of an ankle injury.
With Wimbledon sticking to the ATP and WTA rankings, that means world number three Djokovic automatically moves up to the top seeding as he chases a seventh title at the All England Club, and a 21st grand slam win of his career.
Two-time Wimbledon winner Rafael Nadal is the second seed, with the Spaniard having already won the Australian Open and French Open titles this year to nudge two majors ahead of Djokovic and Roger Federer on the all-time men's list. Federer, still battling his way back from knee surgery, will not play Wimbledon this year and turns 41 in August.
Norway's Casper Ruud, fresh from reaching the French Open final, is the third seed, with Greece's Stefanos Tsitsipas fourth. Spanish teenager Carlos Alcaraz is fifth, while Great Britain's Cameron Norrie, ninth on the list, receives his first top-10 seeding at Wimbledon.
Norrie is bumped up from his world ranking of number 12, given world number eight Andrey Rublev, another Russian, is prevented from competing.
The women's reigning champion Ash Barty has retired since capturing the title last July, so her successor as the dominant player on the WTA Tour, Swiatek, assumes the top seeding.
Swiatek has reeled off 35 consecutive match wins, dominating on hardcourts and clay, but she has less of a grass pedigree, albeit the 21-year-old Pole is a former junior Wimbledon champion.
Last year saw Swiatek lose in the fourth round to Tunisian Ons Jabeur, who is the third seed this time. Estonia's Anett Kontaveit is the second seed, with Wimbledon no longer making any allowances for grass-court prowess, as it used to when devising its seeding lists.
Britain's Emma Raducanu, like Norrie, is a Wimbledon top-10 seed for the first time. The shock US Open champion is seeded 10th, one ahead of the American teenager Coco Gauff.
The format means there will be dangerous unseeded players in the draw, notably Nick Kyrgios and two-time champion Andy Murray in the men's singles.
Serena Williams, the seven-time women's champion, is entered on a wildcard and is also unseeded. Williams, 40, has not played singles since abandoning her first-round match at Wimbledon last year due to injury, but entered this week's doubles event at Eastbourne, partnering Jabeur.
Men's top 10: 1. Novak Djokovic, 2. Rafael Nadal, 3. Casper Ruud, 4. Stefanos Tsitsipas, 5. Carlos Alcaraz, 6. Felix Auger-Aliassime, 7. Hubert Hurkacz, 8. Matteo Berrettini, 9. Cameron Norrie, 10. Jannik Sinner
Women's top 10: 1. Iga Swiatek, 2. Anett Kontaveit, 3. Ons Jabeur, 4. Paula Badosa, 5. Maria Sakkari, 6. Karolina Pliskova, 7. Danielle Collins, 8. Jessica Pegula, 9. Garbine Muguruza, 10. Emma Raducanu
Sinner avoids O'Connell upset at US Open
Jannik Sinner beat Australia's Christopher O'Connell in straight sets to reach the fourth round of the US Open on Saturday, avoiding a similar fate to Carlos Alcaraz and Novak Djokovic.
The men's draw at Flushing Meadows has been blown wide open by early exits for Alcaraz and Djokovic, but the top seed remains in the hunt after a composed performance.
He reached the fourth round for a fourth consecutive year with a routine 6-1 6-4 6-2 victory, setting the tone with several huge groundstrokes in the opening set.
O'Connell never looked likely to fight back as Sinner smashed 46 winners in a ruthless performance, wrapping up his win in one hour and 56 minutes.
The Australian Open champion will face either Tommy Paul or Gabriel Diallo for a place in the last eight, and he was relieved to survive an opening week full of surprises.
"Everything can happen in this sport, so I try to stay on my side of the net and I'm trying to take the tournament day by day," Sinner said in his on-court interview after the win.
"Each opponent is a very tough challenge and [I am] also enjoying every moment on the court. There have been already a couple of upsets, so let's see what's coming.
"But I'm very happy to still be here and hopefully I can play as many matches as possible. But as I said, we go day by day and then we'll see how it goes."
Data Debrief: Sinner heating up
Sinner lost his first set of the tournament to Mackenzie McDonald but has been largely untouchable since then.
He has only lost 18 games across his last nine sets of tennis, an average of two per set.
The Italian's winning streak now stands at seven straight matches, meanwhile, following his triumphant Cincinnati Open run.
US Open: Sabalenka overcomes first set scare to progress in late start
Aryna Sabalenka came from a set down to keep her US Open dream alive as she beat Ekaterina Alexandrova in the early hours at Flushing Meadows.
Sabalenka emerged on court at the Arthur Ashe Stadium at seven minutes past midnight following Novak Djokovic's shock exit from the tournament, and consecutive upsets looked to be on the cards.
However, the Belarusian responded from a disappointing opening set as she looks to avenge her defeat in the showpiece match against Coco Gauff a year ago.
The world number two set up a meeting with Belgium's Elise Mertens as she emerged a 2-6 6-1 6-2 victor in one hour and 40 minutes in New York.
"I don't know what I did, I was just trying to stay low, put as many balls as I can back on that side," Sabalenka said.
"She played incredible tennis in the first set. It was really tough to change it."
"I'm really happy I was able to turn around this match and get this really difficult win. Thanks so much for staying that late."
Data Debrief: Sabalenka survives late, late show
Sabalenka's encounter with Alexandrova was the latest starting match at the US Open, beating Gabriela Sabatini and Beverley Bowes' meeting in 1987 that started at midnight.
The Belarusian, however, will be hoping for a much improved performance in the next round, having produced 27 unforced errors throughout the contest and serving four double faults.
US Open: Djokovic played 'worst tennis ever' in Popyrin loss
Defending US Open champion Novak Djokovic suffered a shock exit at Flushing Meadows as he lost in four sets to Alexei Popyrin.
Djokovic arrived at the tournament with confidence following his gold medal triumph at the Paris Olympics, and was tipped to lift a record-extending 25th grand slam title.
However, the Serbian's hopes of a fifth success in New York were dashed as he followed fellow favourite Carlos Alcaraz out of the competition in the third round.
Popyrin emerged victorious in three hours and 18 minutes, prevailing 6-4 6-4 2-6 6-4 to confirm Djokovic's earliest exit from the tournament in 18 years.
"I have played some of the worst tennis I have ever played," Djokovic said.
"Honestly, the way I felt and the way I played from the beginning of this tournament, third round is a success."
"I tried my best, I didn't have any physical issues. I just felt out of gas, and you could see that. From the first match, I just didn't find myself on this court.
"Life moves on. I'll try to recalibrate and look forward to what's next."
Data Debrief: Another one bites the dust
Djokovic was far from his clinical best, serving a career-high 14 double faults in a grand slam match and committing 49 unforced errors.
The Serbian will also end the year without winning a grand slam title, the first time he has done so since 2017.
But the day belonged to Popyrin, saving 12 of the 16 break points he faced against the world number two, finding particular success with his forehand as 31 of his 49 winners came from that shot.
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