Scottie Barnes is set to be listed as doubtful for the Toronto Raptors' Game 2 against the Philadelphia 76ers.

The Raptors have confirmed Barnes, who is a Rookie of the Year finalist, sprained his left ankle in the fourth quarter of the series-opening 131-111 loss to the 76ers.

That would put the fourth overall pick's involvement in Monday's game in Philadelphia in significant doubt, as coach Nick Nurse acknowledged.

Gary Trent Jr. is ill, meanwhile, and Thaddeus Young has injured his left thumb.

"Listen, it doesn't look good for any of those guys," Nurse said after Sunday's practice.

"They're all going to be listed as probably doubtful, so it doesn't look good for any of them. We'll evaluate them as we go and see where we end up."