Brooklyn Nets head coach Steve Nash insisted his star-studded team must remain humble in their Eastern Conference first-round series against the Boston Celtics.

The second-seeded Nets drew first blood in the NBA playoff series, winning Game 1 104-93 on Saturday.

Boasting Kevin Durant (32 points and 12 rebounds), James Harden (21 points) and Kyrie Irving (29 points), the Nets starred offensively, but they were particularly impressive on defense against the Celtics.

The Celtics carried a six-point lead into half-time but the Nets – behind a strong defensive display – powered past the seventh-ranked Celtics in the second half in Brooklyn.

As the Nets – eyeing their maiden championship – prepare for Tuesday's Game 2, Nash warned against overconfidence on the defensive side.

"If we think that we're the greatest defensive team of all time we're probably asking for a butt-kicking in Game 2," said Nash following Monday's practice.

"If we're humble and hungry and try to stick to our details and our game plan maybe we have a chance to make it difficult for them."

Durant, Harden and Irving combined for 82 of Brooklyn's total points against Boston in Game 1 – 78.8 per cent of the scoring, including 28 of 31 in the third quarter and 48 of 57 in the second half.

"I think that's something that we have the luxury of having those guys that are so difficult to defend in iso situations," Nash added. "But that's not necessarily the way we want to go.

"We were probably more iso heavy the first game because it's all so new, and in default, and Boston switched a lot of stuff. I think that pushed us towards more isos. But it will be interesting to see, it's just all so new that we, like I don't know, if that's going to be something that we dominate the direction we go in or if we're going to be able to get away from that more so and run more action.

"We've got to figure this out as we go so it's hard to answer that question relative to small experience. The luxury is they all are incredible isolation players and it's not the worst thing in the world, but I would like us to get more to where we’re playing off one another."