LeBron James' status for the Los Angeles Lakers is unclear ahead of their meeting with the Denver Nuggets after he reinjured his right ankle in Sunday's loss to the Toronto Raptors.

Superstar James was playing for just the second time since missing 20 straight games due to a right ankle sprain, the longest injury absence during his career.

He put up 19 points, seven rebounds and six assists but exited with six minutes and 42 seconds remaining in the fourth quarter and did not return to the contest.

James said he has no particular worries over the ankle, but that it is imperative for the team that he is fit and firing ahead of the postseason.

"First half it feels really good, obviously warming up for the game everything is going well," he said.

"The last two games at half-time, at the break, it's gotten a little sore on me, got a little tight, obviously coach decided not to put me back in because of that, that's it.

"I really don't have too much level of concern, but I need to be healthy and make sure my ankle is where it was before my injury.

"I need to be smart with it, talk to my trainer Mike and go over with the coaching staff and some of the players as well, most important thing to me is to be healthy and be at full strength when it really matters.

"It matters now to me because I hate sitting out games and not being out on the floor, but I'm also not helping myself or helping my team when I'm not out there at full strength."

Asked whether it is a case of wait and see for the Denver game, James replied: "That's the plan, the plan is to see how I feel, go from there.

"I definitely want to get healthy, not just for myself but for our team, it's definitely challenging right now, but I'll be fine."

The defending champions are in a lull right now, with the Raptors loss representing a sixth defeat over their previous seven games.

It leaves the Lakers seventh in the Western Conference, a finish that would require them to feature in the play-in tournament to make the playoffs – a concept James clearly has little time for.

"It doesn't matter at the end of the day if I'm not 100 per cent, close to 100 per cent it don't matter where we land," he said.

"That's my mindset, if it happens we end up as sixth, or fifth whatever the case may be, you know the playoff whatever that thing is, whoever came up with that s*** need to be fired, but whatever."

The Lakers have been blighted by injury concerns this season and had starting point guard Dennis Schroder unavailable versus Toronto due to health and safety protocols.

James believes the key to getting the Lakers firing again is having a fully fit roster available.

"Our team is predicated on health, we're a team that we need to be healthy and need to be full, if it's not one thing it's the other," he said.

"Today our starting point guard is not in the line-up, that's the biggest thing down the stretch more than the games we're playing is how healthy we're going to be going into the stretch run."