James Harden will not play for the Brooklyn Nets on Thursday, but the Eastern Conference leaders could see LaMarcus Aldridge make his debut against the Charlotte Hornets.
Harden exited Brooklyn's 120-108 win over his former team the Houston Rockets on Wednesday due to tightness in his right hamstring.
The nine-time All-Star had contributed 17 points, eight rebounds and six assists before his departure with just under five minutes remaining in the third quarter.
"I think he told the trainer when he was on the sideline, and they went back to look at it, and they just decided that it wasn't worth risking it," Nets head coach Steve Nash said after the game.
Harden, as well as Blake Griffin, have now been ruled out for the game with the Hornets.
However, having signed for the franchise on Sunday, Aldridge is available along with Landry Shamet, who has missed the previous five games due to a sprained ankle.
Aldridge has not played since March 1 when he was still with San Antonio. He agreed a contract buyout with the Spurs having averaged 13.7 points in 21 games, making him a free agent.
The 35-year-old joined Brooklyn on a deal for the remainder of the season, adding further depth to a star-studded roster.
Following their triumph over the Rockets, the Nets own a 33-15 record to sit atop the East. They have won eight of their previous 10 outings, despite the continued absence of Kevin Durant due to a hamstring injury that has kept him out since February 13.