The Los Angeles Lakers will have to stay afloat without franchise centrepiece Anthony Davis for at least the next few weeks after scans revealed a foot injury that will keep him out indefinitely.

Davis, 28, has been plagued by injuries in recent years, but was enjoying arguably the best season of his career prior to Friday's win against the Denver Nuggets.

Averaging 27.4 points and a career-high 12.1 rebounds per game while playing in 25 of the Lakers' 28 fixtures up to this point, Davis had seemingly rediscovered his best form after only playing a combined 76 games in the past two seasons.

But against the Nuggets, Davis ended up hopping off the floor after a lay-up attempt, briefly returning in the second quarter before sitting out the entire second half.

While the Lakers were hopeful it would only be a minor injury, The Athletic's Shams Charania reported Sunday it will likely cost the eight-time All-Star "at least one month" and that the "Lakers are bracing for an indefinite absence".

With Davis out of the line-up, it remains to be seen if Russell Westbrook returns to the starting group or remains as the designated sixth-man, while backup center Thomas Bryant will undoubtedly see his role expand after impressing with 21 points and six rebounds in 24 minutes after Davis' injury.