Stephen Curry is in "good spirits" but will undergo an MRI on the left shoulder injury that forced him out of the Golden State Warriors' 125-119 loss to the Indiana Pacers on Wednesday.

Curry sustained the injury with 2:04 left in the third quarter as he attempted to strip Jalen Smith of the ball, immediately clutching his shoulder but continuing to run down the court.

The Warriors called a timeout where Curry was assessed by training staff, later heading into the locker room and being ruled out in the fourth quarter.

"He's going to get an MRI tomorrow," Warriors head coach Steve Kerr told reporters. "He was ruled out midway through the fourth. Training staff told me he wasn’t going to play the rest of the night. We'll see how he is tomorrow."

On the pain Curry was feeling, Kerr added: "I didn’t ask about that. I trust their judgement and they said he's not going back in. I just checked in with him briefly but haven’t had a chance to go into detail."

Kerr said 34-year-old eight-time All-Star Curry seemed upbeat in their brief interaction.

 "Steph is always a guy with a great outlook on life so he was in good spirits," Kerr said. "We'll hope for the best."

The reigning NBA Finals MVP had 38 points on five-of-10 three-point shooting with seven rebounds and seven assists until the injury ended his game.

Golden State, who slumped to 2-13 on the road this season, had fought back from a 74-54 half-time deficit but could not overcome the Pacers without Curry.

"Just stunning," Kerr said about Curry's performance. "He basically put us on his shoulders for the minutes he was out there.

"He was generating so much offense, he was getting to the line, he was getting the ball to other people, he was absolutely brilliant.

"I thought the guys did a great job of fighting throughout the third quarter before he got hurt and then after."

Curry is averaging 29.6 points on 49.7 per cent field-goal shooting and 43.2 per cent three-point shooting with 6.6 rebounds and 6.8 assists this season.