All-Star Paul George was ruled out with right knee soreness at half-time in the Los Angeles Clippers' game against the San Antonio Spurs on Saturday.
George had scored 21 points, including making five-of-eight from beyond the arc, before being ruled out at half-time, with the Clippers up 64-48.
The knee concern comes in two-time NBA Finals MVP Kawhi Leonard's second game back in the line-up after missing 12 games due to stiffness in his surgically repaired knee.
The Clippers reached the Western Conference Semifinals in the 2020-21 season but missed the 2021-22 playoffs after struggling with injuries, including Leonard being out for the whole campaign with an ACL injury.
Seven-time All-Star George entered Saturday averaging 23.8 points, 6.3 rebounds and 4.5 assists.
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