Joel Embiid scored 40 points but it was not enough to prevent the Philadelphia 76ers from slumping to a 0-3 start to the new NBA season after a 114-105 home loss to the San Antonio Spurs on Saturday.
James Harden had minimal impact in the second half as Spurs small forward Doug McDermott took control with an eight-point burst, capping his 14 points, which all came in the second half.
The 76ers, who had been beaten by contenders, the Boston Celtics and Milwaukee Bucks, to open their season, squandered Embiid's huge game where he shot 14-of-25 from the field and hauled down 13 rebounds with two blocks.
Harden only added 12 points on four-of-18 shooting, making one-of-six three-point attempts. The former MVP provided 12 assists with nine rebounds and two blocks, but was inconspicuous in the second half with the game up for grabs, with the Spurs defense denying him good looks.
Tyrese Maxey contributed 25 points for the 76ers, including three triples, but Philadelphia slumped to their first 0-3 start since 2016-17.
Devin Vassell (22 points with nine-of-14 field shooting, including four three-pointers) and Keldon Johnson (21 points with eight rebounds) were San Antonio's most productive offensive players.
Mitchell betters LeBron start for Cavs
Donovan Mitchell scored 32 points as he claimed his first win as a Cleveland Cavaliers player in their 128-96 victory over the Chicago Bulls in their home season opener.
Mitchell achieved a feat that not even LeBron James could, becoming the first Cavs player with back-to-back 30-point games to open a season.
The All-Star, who made a high-profile trade from the Utah Jazz to the Cavs in the off-season, landed four-of-six from beyond the arc with nine rebounds and eight assists.
Zach LaVine returned after off-season knee surgery that forced him to miss Chicago's opening two games to top score for the Bulls with 23 points.
Giannis powers Bucks past Rockets
Giannis Antetokounmpo only needed 28 minutes to put on an MVP-like display as the Milwaukee Bucks routed the Houston Rockets 125-105 in their home opener at Fiserv Forum.
Antetokounmpo scored 44 points, shooting 17-of-21 from the field with two three-pointers, along with 12 rebounds and three assists.
The Greek forward became Milwaukee's all-time free throws leader, shooting eight-of-13 from the stripe to exceed Sidney Moncrief's 3,505 record, before sitting out with 8:08 remaining in the fourth quarter.
Jayson Tatum also scored 40 points to lead the 3-0 Boston Celtics past the 0-3 Orlando Magic 126-120, while Paul George had 40 in the Los Angeles Clippers' 111-109 win over the Sacramento Kings.