Harlequins will be without Mike Brown for the rest of the Premiership season, with the England international to undergo surgery on a knee injury.

Full-back Brown, who has won 72 caps for England and made over 300 appearances for Harlequins, is expected to be out for between "six to nine months".

The 34-year-old was left out of England's squad for the Rugby World Cup as Eddie Jones' side made it to the final in Japan, where they were defeated by South Africa.

"Losing Mike is a big loss. He's tried hard to train and play over the past few weeks," Harlequins' head of rugby Paul Gustard said.

"Unfortunately his situation worsened, and it would be damaging to his long-term knee health to try and play."

Brown has played five times for Harlequins this term, having initially sustained the knee issue in pre-season.

England coach Eddie Jones has trimmed his squad ahead of the Rugby World Cup warm-up match against Wales, with Ben Te'o and Mike Brown among those dropped.

After a 12-day training camp in Italy, Jones' side begin their World Cup preparations against the Six Nations champions at Twickenham on Sunday.

Te'o, Brown, Alex Dombrandt and Ben Spencer have been cut from the group, while Jack Nowell remains to continue rehabilitation from an injury.

Jones issued a reminder that the players could be recalled at any stage during England's warm-up campaign, which also includes an away game against Wales and meetings with Ireland and Italy.

"We have worked hard and now move into a four-game preparation phase where the development of the team tactically is paramount. We are grateful for the strong opposition to test our game fitness," Jones told England's official website.

"By the time we fly out [to Japan] on the eighth of September we will be ready to win the Rugby World Cup. We are not there yet but we have four games to get ready.

"Players excluded from being involved in this camp are naturally disappointed but may get another opportunity so they must be ready."

 

England squad:

Forwards: Dan Cole, Luke Cowan-Dickie, Tom Curry, Charlie Ewels, Ellis Genge, Jamie George, Maro Itoje, George Kruis, Joe Launchbury, Courtney Lawes, Lewis Ludlam, Joe Marler, Kyle Sinckler, Jack Singleton, Sam Underhill, Billy Vunipola, Mako Vunipola, Harry Williams, Mark Wilson.

Backs: Joe Cokanasiga, Elliot Daly, Owen Farrell, George Ford, Piers Francis, Willi Heinz, Jonathan Joseph, Joe Marchant, Jonny May, Ruaridh McConnochie, Jack Nowell, Henry Slade, Manu Tuilagi, Anthony Watson, Ben Youngs.

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