Phil Foden scored twice as Manchester City leapfrogged Liverpool and kept the Premier League title race in their own hands by thrashing Brighton 4-0.
Foden moved onto 16 league goals for the season with a first-half brace at the Amex Stadium, seeing a free-kick deflect past a wrongfooted Jason Steele before stroking home after some reckless play from the Seagulls.
De Bruyne had earlier given City the lead with what was his 68th Premier League goal but the first with his head, as Pep Guardiola's men made light of Erling Haaland's injury-enforced absence.
Julian Alvarez added a fourth as City pulled two points clear of Liverpool and within one of Arsenal with a game in hand, knowing five further wins will guarantee they retain their crown.
Brighton, meanwhile, stay in the bottom half with 44 points, having been surpassed by Bournemouth on Wednesday.
Nathan Ake could not keep his shot down when presented with the first half-chance after a low-key start, but City went ahead with a brilliant goal after 17 minutes.
Foden slipped Kyle Walker in on the right flank, and De Bruyne watched the full-back's cross all the way before sending a wonderful diving header into the top-right corner.
There was more fortune about City's second, which arrived just nine minutes later as Foden's free-kick deflected in off Pascal Gross amid Brighton complaints about how Foden won the set-piece.
Brighton only had themselves to blame when Foden got his second after 34 minutes, though. Valentin Barco conceded possession cheaply on the edge of his area, and Foden swept the loose ball into the bottom-left corner.
Ederson denied Joao Pedro as Brighton improved in the second half, but City had further daylight just after the hour mark, Walker breaking in behind and beating Steele to a loose ball, with Alvarez on hand to turn home.
Brighton were enraged when Josko Gvardiol avoided conceding a penalty for a clumsy challenge on Pedro, who skewed wide late on as City – who went close to a fifth through Jeremy Doku late on and face struggling Nottingham Forest next – claimed a statement win.
Foden's star still rising
Foden has emerged as the favourite to be crowned Premier League Player of the Season, and he has gone up a gear in the run-in, also scoring a hat-trick on his last league appearance when City thrashed Aston Villa 4-1 earlier this month.
He was in imperious form again on Thursday, even if Brighton's fans were not happy with the way he went down for the free-kick that ultimately resulted in his first goal.
That strike was Foden's 50th in the Premier League, making him just the third player to score 50 top-flight goals under Guardiola while aged 23 or younger, after Lionel Messi and Erling Haaland.
It is no wonder Brighton's fans are sick of the sight of the England man; he has eight goals in his last eight Premier League appearances against the Seagulls, more than he has scored against any other club in the competition.
Seagulls' wings clipped
Hampered by injuries to the likes of Pervis Estupinan, Kaoru Mitoma and Evan Ferguson, Brighton have seen their European hopes falter in recent weeks and now appear to be limping to the finishing line.
Roberto De Zerbi's team are winless in their last five Premier League games (two draws, three defeats) and sit six points adrift of the top seven with matches against Bournemouth, Aston Villa, Newcastle United, Chelsea and Manchester United to come.
Brighton have even seen their supply of goals dry up, scoring just four times in eight league matches since thrashing Sheffield United 5-0 in February.
Guardiola agrees two-year contract extension with Man City
Pep Guardiola will be Manchester City manager for at least two more seasons after 2024-25, after he signed a two-year contract extension on Thursday.
The 53-year-old was coming to the end of his City deal, which was due to expire at the end of the current campaign, but he has opted to remain at the Etihad Stadium.
The deal itself will take Guardiola's tenure at the club to over a decade, making him City's longest-serving manager since Les McDowall in 1963.
There had been suggestions that he may leave at the end of the season following the announcement that director of football Txiki Begiristain was on his way out.
Guardiola was strongly linked with the England job after Gareth Southgate resigned in the wake of their Euro 2024 final defeat, but the Football Association appointed Thomas Tuchel last month.
“Manchester City means so much to me," Guardiola said. “This is my ninth season here; we have experienced so many amazing times together. I have a really special feeling for this football club.
“That is why I am so happy to be staying for another two more seasons.
“Thank you to everyone for continuing to trust and support me – The Owner, The Chairman Khaldoon, Ferran, Txiki, the players and, of course, the fans… everyone connected to Manchester City. It has always been an honour, a pleasure and a privilege to be here.
“I have said this many times before, but I have everything a manager could ever wish for, and I appreciate that so much.
“Hopefully, now we can add more trophies to the ones we have already won. That will be my focus.”
Having been appointed in 2016, Guardiola is by some distance Manchester City's most successful manager of all time, having won 18 major trophies during his time at the club.
That list includes their first-ever Champions League triumph in 2023 and six Premier League titles, including an unprecedented four on the spin.
He also boasts a 72.04% win percentage across all competitions, which is unsurprisingly the highest of any full-time City manager in history.
Longstaff keen to repay Howe's faith for Newcastle
Sean Longstaff says Eddie Howe's trust is allowing him to play his best football as Newcastle United go in search of a third straight Premier League win against West Ham on Monday.
After a difficult period, Newcastle bounced back by beating Arsenal (1-0) and Nottingham Forest (3-1) to enter the international break eighth in the table, one point adrift of third-placed Chelsea.
Longstaff returned to Newcastle's starting lineup for those matches after temporarily losing his place in their midfield, with Joelinton being pushed into the frontline.
"The midfield group is really strong," Longstaff told BBC Radio Newcastle. "When you look around it's all internationals. It's just about trying to bring my strengths to the team.
"I know the manager trusts me which is the biggest thing. No matter what anyone ever says, the fact he trusts me gives me the most confidence."
Longstaff then continued: "The season we qualified for the Champions League, I tried to enjoy it as much as possible.
"Then, last year there was games every three days and with lads being injured, I think the burden of trying to win every game can mean the enjoyment leaves a little bit. I'm just trying to enjoy the games as much as I can and hopefully being a bit freer will help."
Opponents West Ham, meanwhile, are just five points clear of the relegation zone after signing off for the international break with a goalless draw against Everton, a result that followed on from a crushing 3-0 defeat at Forest.
The Hammers' underwhelming start to the campaign has seen Julen Lopetegui's position questioned mere months after he took the reins, and he is demanding a complete performance next time out.
Speaking to BBC Sport after the Everton game, Lopetegui said: "We had more chances than them. In the second half, we had more clear chances to win the game.
"The first half was a gift for them. We lost 45 minutes. In the second half we did better, we were aggressive and had chances to win.
"The matches aren't about 45 minutes. They are 90 minutes and stoppage time. That's why I'm not happy, for sure. I think we can, and have to, do better."
PLAYERS TO WATCH
Newcastle United – Harvey Barnes
Only against Aston Villa (nine) has Barnes been directly involved in more Premier League goals than he has against West Ham (eight – six goals, two assists).
He has either scored or assisted in each of his last four against the Hammers (four goals, one assist), finding the net in each of the last three.
West Ham – Michail Antonio
Only Wolves frontman Jorgen Strand Larsen (16) has made more hold-ups while retaining possession in the Premier League this season than West Ham striker Antonio (15).
Antonio is retaining possession with 71% of his hold-ups in the competition this term (15/21), the highest ratio of any player to attempt 10 or more. Lopetegui's side are likely to spend plenty of time under pressure on Monday, but he could provide them with an outlet.
MATCH PREDICTION – NEWCASTLE UNITED WIN
Newcastle have won their last two Premier League games and are looking to win three in a row for the first time since September 2023 – this is the sixth occasion since then that they have won twice in a row in the league.
They have lost just one of their last 10 Premier League games against West Ham (five wins, four draws) and are unbeaten in all five against the Hammers under Howe (two wins, three draws). They triumphed 4-3 when the sides last met at St James' Park in March.
West Ham, meanwhile, have kept just two clean sheets in their last 28 Premier League away games, conceding 66 goals (2.4 per game).
Indeed, in 2024, they have conceded more away goals in the top-flight (35) than any side.
Lopetegui's men have also failed to score in their last two league games, as many as in their previous 14 beforehand. Only five teams have a worse difference between their expected goals (xG) and expected goals against (xGA) figures than West Ham (-2.97) this term.
OPTA WIN PROBABILITY
Newcastle United – 58.9%
West Ham – 19.7%
Draw – 21.4%
Maresca confirms James will miss Leicester clash with hamstring injury
Enzo Maresca confirmed that Reece James has suffered another hamstring injury and will miss Chelsea's Premier League fixture against Leicester City on Saturday.
James made 11 appearances in all competitions last season before undergoing hamstring surgery, which was designed to help him overcome his series of injuries.
He returned to action in Chelsea's 2-1 defeat to Liverpool last month, completing his first 90 minutes in 569 days a week later against Newcastle United.
Though his latest injury setback is his eighth hamstring problem in four years, while also picking up thigh, ankle and muscle issues along the way.
Maresca played down concerns about a long-term lay-off but confirmed James will miss Saturday's match at the King Power Stadium.
"We have just one injured player and that's Reece, who unfortunately felt something small in training two days ago, and we don't want to take a risk for the weekend," he said.
"It's a hamstring, muscular problem. We will see, we don't know for how long, for sure [we want him fit for longer]. At the moment it is not happening, but we hope it will happen soon.
"He is out this weekend, but hopefully he can be back soon. It's probably difficult that he can be available for the Conference League [next Thursday], but hopefully soon."
Since his debut season in 2019-20, James' most appearances came in the 2020-21 campaign, featuring 47 times in Chelsea's Champions League winning season.
His best run of matches during that time is six in May 2021, but he managed just 482 minutes under Mauricio Pochettino in all competitions last season.
James has, however, managed more minutes (6138) in the Premier League since the 2020-21 season than any other player in the current Chelsea squad, though Enzo Fernandez (4375) is second, despite only joining the club in January 2023.
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