Bayer Leverkusen are one victory away from a first Bundesliga title after edging past 10-man Union Berlin.
Florian Wirtz scored the only goal of the 1-0 victory deep in first-half injury time after Robin Gosens was shown a red card.
Union succeeded in keeping it to one but, with Bayern Munich losing again, it was enough to move Xabi Alonso’s side 16 points clear at the top of the table with six games remaining.
Frederik Ronnow had made fine saves from Borja Iglesias and Alex Grimaldo before the game burst into life in first-half injury time.
First Gosens, who had been booked early on, was shown a second yellow card for a foul just outside the box.
The resulting free-kick caused chaos in the Berlin penalty area and, after a VAR check, the referee ruled Christopher Trimmel had handled and pointed to the sport, with Wirtz making no mistake.
Leverkusen had the majority of the play in the second half as they sought a second but Ronnow refused to be beaten again, saving impressively from Nathan Tella and Iglesias.
Real Madrid dealt Vinicius injury blow before Champions League clash at Liverpool
Vinicius Junior is set to miss his side's Champions League clash at Liverpool after sustaining a leg muscle injury, Real Madrid announced.
Reports suggest that Vinicius could be sidelined for at least three weeks, which means he could miss up to seven games in all competitions before the winter break, including against Girona and Athletic Bilbao in LaLiga and a Champions League visit to Atalanta.
The Brazilian played all 90 minutes against Leganes on Sunday, setting up Kylian Mbappe's opener in Madrid's 3-0 win.
In the Champions League, he is the second-highest scorer, having netted four times in four matches, while only Rico Lewis (13) has created more chances than him (12).
"Following tests carried out today on our player Vini Jr by the Real Madrid Medical Services, he has been diagnosed with an injury to the biceps femoris in his left leg. Pending evolution," Madrid said in a statement.
Vinicius is the latest to join the club's lengthy injury list, which includes key players like Rodrygo, Eder Militao, Dani Carvajal, Lucas Vazquez, Aurelien Tchouameni and David Alaba.
Madrid are second in the LaLiga standings on 30 points. However, after two losses in their last three games in the Champions League, Carlo Ancelotti's side could be in trouble with a bad result at Anfield. They are 18th in the 36-team table with six points from four games.
Mbappe position switch works wonders for Ancelotti
Carlo Ancelotti was satisfied his tactical decision to switch Kylian Mbappe's position in attack paid off in Real Madrid's 3-0 win over Leganes.
Mbappe scored his seventh goal of the season to help Madrid to a comfortable victory in LaLiga on Sunday.
However, his position in Madrid's front line has been a topic of debate since he joined the Spanish champions, with Mbappe having often played out wide while at Paris Saint-Germain.
And Ancelotti elected to switch Mbappe out to the left flank against Leganes, with Vinicius Junior spearheading Los Blancos' attack.
"Mbappe played on the left side, where he did well, and Vinicius on the inside," Ancelotti told reporters.
"We have to highlight their play to open the scoring. They did very, very well. Mbappe scored, after a fantastic assist from Vinicius. Little by little, they're both improving.
"Kylian is more used to playing there and today, for the team and for him, it was the best thing.
"Because playing on the outside brings more effort and Vinicius was back on Thursday. Meanwhile, Kylian had been training here for a week and a half, he was fresher."
Mbappe was not called up by France coach Didier Deschamps for this month's Nations League games, despite being Les Bleus' captain.
With an injury crisis at the back and a trip to Anfield to face Premier League and Champions League leaders Liverpool coming up, Ancelotti added he was hopeful of Lucas Vazquez, who has a hamstring strain, and Aurelien Tchouameni, who is recovering from a sprained left ankle, returning to action.
He was also upbeat about the contribution of Federico Valverde, who scored from a free-kick while filling in at right-back.
"The truth is that Fede, at the back, has done very well," said Ancelotti of the Uruguayan, who also wore the captain's armband.
"He's a fantastic fullback. After Dani Carvajal and Lucas Vazquez, the best right-back in the world. His problem is that he can play at this level in many positions and is the coach's problem to choose the best position for the team.
"Let's see if Lucas and Tchouameni can recover. If not, we will make decisions."
Jude Bellingham netted Madrid's other goal as Ancelotti's team closed to within four points of LaLiga leaders Barcelona, who drew 2-2 with Celta Vigo on Saturday.
Madrid also have a game in hand on Hansi Flick's side.
Dortmund got 'fully deserved victory' over Freiburg, says Sahin
Nuri Sahin praised Borussia Dortmund for getting "a fully deserved victory" over nine-man Freiburg in the Bundesliga on Saturday.
Dortmund remained perfect on home soil this season as they cruised to a 4-0 win at Signal Iduna Park after Patrick Osterhage and Junior Adamu were both sent off for the visitors.
Maximilian Bieier and Felix Nmecha scored in the first half before Julian Brandt and Jamie Gittens secured the points in the second during a dominant display as they limited Freiburg to just three shots on target at the other end.
Dortmund have now won 11 home games in a row in all competitions. Since the Bundesliga was founded, they have won more consecutive home matches in a row only once, winning 14 in a row at home in 1994.
Sahin has come under pressure recently for the Black and Yellow's less impressive away form, but he was delighted with the showing he saw from his side.
"We started very well. We controlled the spaces. We allowed very little," Sahin said.
"Overall, it was a mature performance from my boys. We scored great goals, showed good energy.
"We kept them away from our goal throughout. It was a fully deserved victory and I, as a coach, am very satisfied."
Dortmund were, however, without Serhou Guirassy, who is their top scorer in the Bundesliga with six goals, as he pulled out of the game due to a virus.
Next up for Sahin's side is a trip to Dinamo Zagreb in the Champions League, and the head coach is hopeful he will be available for that tie.
"[Saturday] morning again, we got the bad news. Serhou tried everything to play today, but it did not work," Sahin added.
"I hope it will be enough for Zagreb. He is a very important player for us."
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