Premier League leaders Arsenal went into the international break with an eight-point advantage, and the Gunners will be hoping for a favour from Liverpool on Saturday.
Before Arsenal host strugglers Leeds United, Liverpool travel to the Etihad Stadium to face second-placed Manchester City.
Pep Guardiola's side have a game in hand on Arsenal, but surely they must beat the Reds to give themselves a realistic chance of retaining the title.
Elsewhere, there are more huge fixtures at the bottom of the table, including West Ham v Southampton, while Newcastle United and Manchester United play in a repeat of February's EFL Cup final.
Manchester City v Liverpool
Liverpool, who won the reverse league fixture 1-0, are looking to complete the league double over City for what would be just a second time in the last 17 seasons, previously doing so in Jurgen Klopp's debut campaign in 2015-16.
Mohamed Salah has scored in all three of Liverpool's games against Man City this season, in the Premier League, Community Shield and EFL Cup. The last Liverpool player to score in four different games against an opponent in a single campaign was Ian Rush, netting in five meetings with Everton in 1986-87.
Erling Haaland has scored 42 goals in all competitions for City this season, including six hat-tricks (all at the Etihad). Only two players have scored more in a single campaign for a Premier League club (since 1992-93) – Ruud van Nistelrooy in 2002-03 and Salah in 2017-18 (both 44).
Best bet – City to avoid defeat: City have lost just one of their last 13 Premier League home games against Liverpool (W7 D5), going down 4-1 in November 2015 under Manuel Pellegrini. Guardiola's team have won their last three top-flight games, but have yet to win four in a row this season.
Long shot – Liverpool to win: Liverpool have won more Premier League games against reigning champions than any other side (23). They are aiming to achieve their first such double since 2013-14, beating Manchester United 1-0 at home and 3-0 away. However, they have taken just 12 points from their 13 Premier League away games this season (W3 D3 L7), compared to 30 at home.
Opta prediction: Despite the fierce rivalry over recent years, City are the big favourites for this game, with Opta's supercomputer ranking their chances of victory at 50.9 per cent. The draw is at 26.4 per cent, with Liverpool handed a 22.7 per cent chance of success.
Arsenal v Leeds United
Leeds have won just two of their 23 Premier League games against the league leaders (D9 L12), though both victories came away from home (v Middlesbrough in August 2000 and Man City in April 2021). They have lost all four such games against Arsenal by an aggregate score of 14-2.
Arsenal have won their last six Premier League games, their joint-longest such run under Mikel Arteta. They last won seven in a row between August and October 2018 under Unai Emery.
Arsenal’s top scorer in the Premier League this season is Gabriel Martinelli with 13 goals. The last player to score more while aged 21 or under in a single campaign in the division was Dele Alli in 2016-17 (18).
Best bet – Bukayo Saka to score or assist: Only Erling Haaland (33) and Harry Kane (23) have been involved in more Premier League goals than Saka this season (22), with the winger the only player so far to reach double figures for both goals (12) and assists (10).
Long shot – Leeds to keep a clean sheet: Since a 0-0 draw in their first Premier League away game against Arsenal in February 1993, Leeds have not drawn or kept a clean sheet in any of their subsequent 13 league visits to the Gunners (W3 L10), shipping 31 goals in total.
Opta prediction: Opta do not give Leeds much chance at Emirates Stadium (15.5 per cent). Arsenal are huge favourites, with a 61.6 per cent win probability, while the draw is ranked at 22.9 per cent.
West Ham v Southampton
Coming into this weekend's games, Southampton have picked up the highest share of their Premier League points this season away from home (57 per cent - 13/23). Meanwhile, only Nottingham Forest (77 per cent) have a higher share of points won at home in 2022-23 than West Ham (75 per cent - 18/24).
Southampton have picked up as many points in their six Premier League games under Ruben Selles (8 – W2 D2 L2) as they had in their 17 league matches beforehand (W2 D2 L13).
Sides starting the day bottom of the Premier League have won 11 league matches this season, four more than the whole of last term (seven), and the most in a single campaign in the competition since 2017-18 (12). Southampton have been responsible for three of those victories by bottom-placed sides in 2022-23, a joint-high (also Leicester).
Best bet – James Ward-Prowse to create two chances: Coming into this weekend's games, only Kieran Trippier (49) has created more chances from set plays than Ward-Prowse (35) in the Premier League this season, while the Southampton captain is the only player to create 25+ chances from both open play (27) and set pieces (35) in the division this term.
Long shot – A goalless draw: No other sides have kept fewer clean sheets in the Premier League this season than Southampton (four) and West Ham (five)
Opta prediction: Despite both of these teams struggling, it is West Ham who Opta give 51.4 per cent chance of claiming all the points. Southampton have been responsible for three of the seven victories by the bottom-placed side this season, but the likelihood of them succeeding this time stands at 21.7 per cent.
Newcastle United v Manchester United
Following their goalless draw at Old Trafford in the reverse fixture, Newcastle are looking to keep a clean sheet in consecutive Premier League games against United for the first time since May 1997.
No player has scored more winning goals in the Premier League this season than Marcus Rashford, with nine of his 14 strikes being the winner. Only two United players have ever scored more winning goals in a single campaign in the competition – Cristiano Ronaldo (12 in 2007-08) and Wayne Rooney (10 in 2009-10).
Coming into this weekend's fixtures, only Bournemouth (38), Nottingham Forest (32) and Leicester (30) have conceded more away goals in the Premier League this season than United (27). Indeed, only in four different Premier League campaigns have the Red Devils conceded more on the road – 1999-00 (29), 2001-02 (28), 2018-19 (29) and 2021-22 (35).
Best bet – United to win: United have won more Premier League away games against Newcastle than any other side (14). However, they have lost two of their last five such visits (W2 D1), having lost just one of their previous 13 at St James' Park. Newcastle are winless in six Premier League games against Man Utd (D2 L4), though the last two have both been drawn.
Long shot – Rashford and Alexander Isak to score: Rashford has been involved in seven goals in his eight Premier League starts against Newcastle (four goals, three assists) – only against Arsenal and Leicester City (nine each) has he been involved in more. Isak, meanwhile, has scored six goals in 10 Premier League appearances for Newcastle this season, including three in his last two.
Opta prediction: This could prove a big game in the top-four race, with Newcastle only three points behind third-placed United. The visitors are made very slight favourites (36.8 per cent to 34.2 per cent). The draw is given a 29 per cent chance.
Nzonzi: Sevilla's Europa League dominance comparable to Real Madrid's Champions League aura
Sevilla's aura in the Europa League is similar to the fear Real Madrid instil into Champions League opponents, says Steven Nzonzi.
Jose Mourinho's Roma were the latest team to fall foul of Sevilla in a Europa League final as the Andalusian side extended their remarkable record of wins in UEFA's second-tier club competition to seven.
Only five teams – Madrid, Barcelona, Milan, Liverpool and Bayern Munich – have won more major European honours than Sevilla, who beat Roma 4-1 on penalties after a tightly contested 1-1 draw in Budapest.
Nzonzi, who helped Unai Emery's Sevilla beat Liverpool in 2016 to seal a third straight Europa League crown, believes the club have now created such an air of dominance in the tournament that they can be compared to Madrid, who have won the Champions League/European Cup on 14 occasions.
He told Stats Perform: "I don't know if they are the greatest team, it is hard to say but, of course they are one of the best teams to play in that competition.
"I really feel they have that energy that experience going on in that competition and it makes them win, it reminds me of Real Madrid in the Champions League.
"Real Madrid are another level and the won the Champions League more [times] than Sevilla won the Europa League but [Sevilla are] one of those teams when they are in that competition, you feel like anything is possible and they can win it."
Asked why Sevilla are able to sustain such success in the Europa League, Nzonzi replied: "It's really hard to say because sometimes you play against other teams that are better than you.
"They may play better or on paper have better players than you but you are still the one ending the game or winning the competition.
"I think it's the whole vibe, the whole energy going on, in the changing room, in the club there is a confidence because if you already won it one, two, three, four, five, six times, you have the confidence to win it again and feel that you are the superior team in that competition.
"Then there is the fans. I watched the semi-final and when Juventus played in Sevilla, I looked at the fans and I said, 'They [Juve] are not winning, the fans are just so good'. They are just pushing you so much, it is very difficult for the other team to feel confident.
"I think the big thing with Sevilla is the fans. I feel it is a big part of the energy that is happening for them in the Europa league.
"I remember going to the stadium and having a lot of fans not stopping the bus, but following the bus. [In the 2015-16 final] there were much more Liverpool fans in the stadium, but we still could feel the energy of the Sevilla fans."
Sevilla were embroiled in a relegation scrap in LaLiga until Jose Luis Mendilibar replaced Jorge Sampaoli in March, and while they are set for a mid-table finish, their Europa League triumph means Champions League football beckons next term.
"It feels like the Europa League has big things to do with Sevilla, because it is just incredible," Nzonzi added.
"And I think it is even better because they are not qualifying for the Champions League through LaLiga."
Caoimhin Kelleher should leave Liverpool to lift Republic career – Stephen Kenny
Republic of Ireland boss Stephen Kenny has admitted goalkeeper Caoimhin Kelleher needs to leave Liverpool this summer if he is to fulfil his potential.
The 24-year-old will meet up with his international colleagues ahead of the Euro 2024 qualifiers against Greece and Gibraltar later this month and resume his battle with Gavin Bazunu for the role of Ireland’s number one.
However, the man who played in the Reds’ 2022 Carabao Cup final victory over Chelsea is still firmly in the shadow of Brazilian star Alisson Becker at Anfield and made just four club appearances for his club last season, and Kenny expects him to seek pastures new before the new campaign gets under way.
He said: “I would fully expect that. It’s not right normally to speak about a player moving, but he’s at the stage where he’s behind probably one of the best goalkeepers in the world and it’s not going to get any easier.
“He can’t afford not playing. He knows that and he’s known that for a while. It’s not easy. There’s a process you go through with a club like that and I think and it wouldn’t be a surprise for him to move in the summer, and he knows that.
“I think he’s ready to go and play regularly because he needs to. It’s hard to leave Liverpool, it’s such an iconic club, but he’s not so young now. He’s 24 and he needs to play and he knows that.”
Kenny faces something of a conundrum with his keepers, with Kelleher, Bazunu and Mark Travers all at Premier League clubs, but struggling for regular football.
Bazunu, 21, lost his place at Southampton as they fought, ultimately unsuccessfully, to stave off relegation, although his international manager is optimistic his confidence will not be affected by that experience.
Kenny said: “He’s done remarkable, really, in a short career, Gavin as well. For one so young, he’s done remarkably well. He’s always looked very confident playing for us.”
Full-back Matt Doherty is another man who has been starved of football this season having made just two brief appearances as a substitute for Atletico Madrid since joining them from Tottenham in January.
Kenny said: “I’m sure when he took that move, he knew he would find it hard for games, but he thought he would play an amount of games, for sure. He couldn’t have envisaged that he wouldn’t play at all. That was frustrating for him and tough mentally to deal with.”
Kenny has been forced to omit Rotherham striker Chiedozie Ogbene from his 25-man squad for the games against Greece in Athens on June 16 and Gibraltar in Dublin three days later after he failed to recover from a hamstring injury.
However, 18-year-old Brighton counterpart Evan Ferguson will report for a nine-day training camp in Antalya full of confidence at the end of his breakthrough season.
Kenny said: “He’s taken everything in his stride, he’s a single-minded individual and nothing has fazed him. He seems to be able to adapt to whatever the occasion demands.”
Fiorentina aim to take out frustration on West Ham in Conference League final
Fiorentina will look to take their Coppa Italia frustrations out on West Ham in next week’s Europa Conference League final.
The Viola, seeking a first major trophy since 2001, have reached two finals this season but missed their first opportunity to end that wait for silverware when they were beaten 2-1 by Inter Milan last week, with Lautaro Martinez’s brace cancelling out an early Nicolas Gonzalez strike.
That has added to Fiorentina’s motivation going into Wednesday’s final against the Hammers in Prague on Wednesday.
Goalkeeper Pietro Terracciano, speaking to Sky Sports Italia at a media day on Thursday, said: “We must face all games in the best way knowing that the final is very important for us and the city. It’s the game of the season in Prague.
“It will be different from the Coppa Italia final. We’ll face a different opponent. But we played a great game against Inter and I am sure the same will happen with West Ham. This is our certainty, we’ll give our all to win the trophy.”
Coach Vincenzo Italiano said the key to success would be cutting out the mistakes that cost Fiorentina against Inter.
“We’ve had a great season, and we deserved the chance to play for this trophy, we are aware of our strength but we know that every error makes the difference in a final,” said Italiano.
“Every detail matters and we want to give joy to our fans.”
Fiorentina sit ninth in Serie A going into their final league fixture away to Sassuolo on Friday night, before all attention turns to West Ham.
Asked about David Moyes’ side, Italiano said: “They haven’t done well in the league, but they have a very competitive team with top-class players and a competent coach. We must focus on ourselves and be free in our minds.”
For last week’s goalscorer Gonzalez, losing to Inter is not the only disappointment he has endured this season.
The 25-year-old midfielder has been capped 22 times by Argentina but missed out on their World Cup squad, watching on from home as his team-mates lifted the trophy in Qatar.
Wednesday’s final gives him a much-needed opportunity to win a medal himself.
“We are experiencing so many emotions, I am happy to have reached two finals,” he said. “We lost the first one, but now there is another big game and we want to win.
“Some things hurt me last year, especially not going to the World Cup. I wasn’t fit, but some thought it was a fake injury. I never did it, I always want to be 100 per cent when I play football. We have 90 minutes and we want to make the difference.”
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