Juventus have confirmed they intend to appeal against their 15-point deduction as they consider it "a clear injustice towards millions of fans".
The Italian Football Federation (FIGC) confirmed the punishment on Friday following an investigation into the 36-time Italian champions' past transfer dealings.
Juve have slipped from third in Serie A to 10th and are 12 points off the Champions League places with 20 matches left to play.
The FIGC also hit the club's former president Andrea Agnelli and former chief executive Maurizio Arrivabene with two-year bans from Italian football.
Former sporting director Fabio Paratici, who is now at Tottenham, has been given a 30-month ban.
However, the Bianconeri have always denied any wrongdoing and hope the sanctions will be overturned on appeal.
A statement by the club's lawyers read: "Today's acceptance of the appeal for revocation by the Federal Court of Appeal seems to us to constitute a clear unequal treatment to the detriment of Juventus and its managers compared to any other club or registered player.
"We are waiting to carefully read the reasons for presenting the appeal before the Sports Guarantee College. However, we point out, as of now, that only Juventus and its managers are attributed the violation of a rule, which the sports justice itself had repeatedly recognised did not exist.
"We believe that this is a clear injustice also towards millions of fans, which we trust will soon be remedied in the next level of judgement."
Turin Public Prosecutor's Office had been seeking a nine-point deduction following a hearing earlier on Friday.
But the FIGC announced a harsher punishment after Juve were found to have used transfers to artificially boost their balance sheet.
The sanctions come on the back of chairman Agnelli and the rest of the Bianconeri's board resigning en masse last year.
That came in the wake of an investigation being launched into financial violations during their time in charge.
A separate ruling made last year acquitted Juve and other clubs of their financial conduct within Serie A, with a case centred on player values in exchanges and transfers.
But football prosecutors reopened the case against Juve after seeking new documents collected by public prosecutors in Turin surrounding the club's conduct.
Brentford 3-1 Southampton: Bees begin life after Toney with comfortable win
Brentford began life without Ivan Toney with a comfortable 3-1 victory over Southampton.
Bryan Mbeumo’s brace and a Yoane Wissa goal proved to be the difference between the two sides and condemned the Saints to their third straight loss since promotion back to the Premier League.
With departed striker Toney watching in the stands after his move to Al-Ahli in Saudi Arabia, the hosts proved too strong for Russell Martin’s men. They created the superior chances and capitalised on an error-strewn performance from Southampton’s backline.
Mbeumo opened the scoring on the stroke of half-time before doubling the lead halfway through the second period and Wissa then got on the scoresheet moments later to continue Brentford’s strong start to the campaign. Yukinari Sugawara bagged a consolation in injury time for the Saints.
Brentford sit in fifth place ahead of the first international break, while Southampton are second-bottom of the league table with zero points.
Data debrief: Wissa continues to prove effective at home
Wissa now has five goals and two assists in his last seven matches at the Gtech Community Stadium.
Brentford have recorded consecutive home league wins for the first time since last November, and the first time in their opening home games since August 2018.
Brentford 3-1 Southampton: Bees begin life without Toney with comfortable win
Brentford began life without Ivan Toney with a comfortable 3-1 victory over Southampton.
Bryan Mbeumo’s brace and a Yoane Wissa goal proved to be the difference between the two sides and condemned the Saints to their third straight loss since promotion back to the Premier League.
With departed striker Toney watching in the stands after his move to Al-Ahli in Saudi Arabia, the hosts proved too strong for Russell Martin’s men. They created the superior chances and capitalised on an error-strewn performance from Southampton’s backline.
Mbeumo opened the scoring on the stroke of half-time before doubling the lead halfway through the second period and Wissa then got on the scoresheet moments later to continue Brentford’s strong start to the campaign. Yukinari Sugawara bagged a consolation in injury time for the Saints.
Brentford sit in fifth place ahead of the first international break, while Southampton are second-bottom of the league table with zero points.
Data debrief: Wissa continues to prove effective at home
Wissa now has five goals and two assists in his last seven matches at the Gtech Community Stadium.
Brentford have recorded consecutive home league wins for the first time since last November, and the first time in their opening home games since August 2018.
Pirlo sacked as Sampdoria head coach after dismal Serie B start
Andrea Pirlo has been sacked as Sampdoria's head coach after just over a season at the helm.
Pirlo, who managed Juventus for the 2020-21 campaign, has been relieved of his duties after an underwhelming start to their Serie B season.
After finishing seventh in Italy's second tier last term, the 45-year-old was given the green light to try and return to Serie A at the second time of asking.
However, an opening day draw with Frosinone was followed up with back-to-back defeats to Reggiana and Salernitana, leaving them second-bottom in the division.
During his time in charge, Pirlo won 18 of his 45 matches in charge (D10 L17), averaging 1.42 points per game, a total only bettered by his time with Juventus (2.15).
Sampdoria return to the Stadio Luigi Ferraris this weekend in search of their first three points of the season, welcoming Bari to Genoa on Saturday.
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