Manchester City sealed the Premier League title in dramatic fashion as they came from behind to beat Aston Villa 3-2.
It meant Liverpool's own comeback win over Wolves was rendered meaningless, as Jurgen Klopp's team finished second, one point off the pace.
Chelsea capped an ultimately underwhelming campaign by beating Watford, who will be joined in the Championship next season by Burnley – the Clarets relegated by a defeat to Newcastle United, while Leeds United beat Brentford to stay up.
Already safe Everton were hammered 5-1 at Arsenal, but the Gunners' big win was not enough to get them into the Champions League as Tottenham thrashed Norwich City.
Elsewhere, Manchester United lost 1-0 to Crystal Palace to end a dismal season for them, but they did at least qualify for the Europa League, as West Ham were beaten 3-1 by Brighton and Hove Albion, meaning David Moyes' team will take a place in next season's Europa Conference League.
For the final time this season, Stats Perform looks at the best facts from across the Premier League's fixtures, using Opta data.
Manchester City 3-2 Aston Villa: Gerrard's dream dashed by Gundogan
Steven Gerrard never managed to win the league with Liverpool but he looked destined to give his old club a huge helping hand when Villa took a 2-0 lead at the Etihad Stadium.
Former Liverpool playmaker Philippe Coutinho put Villa 2-0 up midway through the second half, and he has now scored five goals against City in the Premier League, more than against any other team.
However, substitute Ilkay Gundogan became the first player to score twice from the bench for City since Sergio Aguero did so against Everton on the final day of last season, as he inspired a comeback for the ages.
Gundogan scored either side of Rodri's equaliser – there were just 12 minutes and 22 seconds between City going 2-0 down, and then leading 3-2 in the match.
City have now won a sixth Premier League title, with four of those coming in the past five seasons under Pep Guardiola, while it was the first time the club have come from two goals down to win a top-flight game since February 2005.
Liverpool 3-1 Wolves: Salah seals share of Golden Boot but Reds settle for second
There will be no quadruple for Liverpool, who nevertheless have a Champions League final to look forward to on May 28.
Liverpool have finished the season on 92 points, the second-highest total by a side that did not go on to win the title in English top-flight history, behind only their own 97 in 2018-19.
Sadio Mane cancelled out Pedro Neto's opener (the third-earliest Premier League goal for Wolves, timed at 02:11), with the Senegal star having scored six goals on the final day of the Premier League season for Liverpool, the most of any player at the club – three of those strikes have come against Wolves.
Mohamed Salah finally got Liverpool in front in the 84th minute to take him to 23 goals for the season, meaning he shares the Golden Boot with Son Heung-min. Andrew Robertson added a third, which means Wolves have now lost their last 11 league meetings with the Reds by an aggregate score of 24-3.
Arsenal 5-1 Everton, Norwich City 0-5 Tottenham: North London rivals go big
It has been a frustrating end to the season for Arsenal, who let a Champions League place slip out of their grasp and fall into Tottenham's lap.
The Gunners put five past a much-changed Everton team. Arsenal have now scored more goals against the Toffees than any other side has netted against another team in Premier League history (117).
Arsenal are also unbeaten in their final league game in each of the last 17 seasons (W15 D2), winning the last 11 in a row, while Everton have lost their final league game in five of the last six seasons (D1), conceding at least three goals in each defeat.
Only in 1993-94 (22) have Everton lost more games in a Premier League season than the 21 defeats they have suffered in the competition this term, but they have nevertheless stayed up. Norwich were not so lucky, and their place at the bottom was confirmed by a hammering at home to rampant Spurs.
Tottenham ended the season with 71 points, only in three previous Premier League campaigns have they had more points – 86 in 2016-17, 77 in 2017-18 and 72 in 2012-13.
Son Heung-min is the first Asian player to win the Premier League Golden Boot, while Harry Kane has scored nine goals on the final day of Premier League seasons, the joint-most in the competition's history.
Burnley 1-2 Newcastle United, Brentford 1-2 Leeds United: Another late show caps Whites' survival
Leeds defeated Brentford thanks to a last-gasp Jack Harrison goal, and only City (nine) have netted more goals in the 90th minute than the Whites have this season (eight).
That effort, combined with Burnley's defeat at Newcastle, ensured Leeds avoided the drop and it was Burnley who were relegated.
Burnley netted their 300th Premier League goal, the 32nd side to hit that milestone in the competition, but it was not enough to inspire a comeback after Callum Wilson's double.
The Clarets faced a team in form, with only Liverpool (51), City (43) and Tottenham (41) having picked up more points than Newcastle in 2022.
‘No regrets’ says Pep Guardiola after Manchester City loss in Champions League
Pep Guardiola insisted there were no regrets after Manchester City’s bid to retain their Champions League crown ended in a heartbreaking penalty shoot-out loss to Real Madrid.
The holders were beaten 4-3 on spot-kicks by the Spanish giants after their quarter-final tie ended 4-4 on aggregate – 1-1 on the night – despite a dominant display from Guardiola’s side in the second leg at the Etihad Stadium.
City fell behind early to a Rodrygo goal but created a host of chances as they sought to regain control of the tie but Kevin De Bruyne’s 76th-minute equaliser was their only reward.
City manager Guardiola said: “I would have preferred to win but congratulations to Real Madrid, they defended so deep with incredible solidarity and we did everything.
“I don’t have any regrets about what we have done. Always we try to create more chances and concede less, because we believe that helps you to win and we did everything.
“We played exceptionally in all departments and unfortunately we could not win.”
Bernardo Silva and Mateo Kovacic both missed in the shoot-out, with the former’s effort proving a particularly comfortable save for Andriy Lunin.
Guardiola refused to blame the Portuguese for his failure to register.
He said: “Bernardo asked to take it, he’s a reliable player and decided to shoot in that way. What a game he had played. It happens.”
Guardiola also had no complaints about Real’s tactics, with the Spanish side forced to sit back and defend deep for much of the game.
“I don’t judge,” he said. “I’m not here to do this. It’s football. In this competition, that’s the way football happens.”
City’s loss also ended their hopes of winning a second successive treble and they must now pick themselves up for Saturday’s FA Cup semi-final against Chelsea at Wembley.
Guardiola said: “Now we will rest and on Friday we travel to London to play the game.
“We will see how people will react. Of course the recovery is easier when winning, rather than losing, but it is the semi-final of the FA Cup and we will try to compete as much as possible.”
Real manager Carlo Ancelotti admitted the strength of City had forced them to soak up pressure and look to take the tie on penalties.
The veteran Italian said: “We defended really, really well. This was about survival. Madrid is a club based on always fighting to stay in situations where there seems to be no way out – but we always find a way.
“By the time the penalty shoot-out came, we were totally convinced we’d go through.
“This is about the only way you can come to City and win. You work, sacrifice and win however you can.”
Penalty heartache for Manchester City as Real Madrid end Champions League dream
Manchester City’s dreams of retaining the Champions League were shattered after a dramatic penalty shoot-out loss to Real Madrid.
Bernardo Silva and Mateo Kovacic both missed from the spot as City were beaten 4-3 on penalties after their pulsating quarter-final tie ended 4-4 on aggregate.
Rodrygo had given Real an early lead in the second leg at the Etihad Stadium but City otherwise dominated and, after creating a host of chances, finally made it 1-1 on the night through Kevin De Bruyne in the 76th minute.
De Bruyne spurned a good chance to win the tie in normal time and Erling Haaland had earlier hit the crossbar but it was the competition’s record 14-time winners who ultimately prevailed.
It was harsh on City, who had immediately set out their stall to dominate possession.
Despite their control, however, the hosts looked vulnerable to the counter-attack and were caught out after 12 minutes.
Jude Bellingham brilliantly controlled a high ball with the outside of his foot and found Federico Valverde, who in turn fed Vinicius Junior in the box.
Vinicius pulled back for Rodrgyo and, although Ederson did well to beat out his powerful first-time shot, he could do nothing to deny his fellow Brazilian on the rebound.
City stepped up the tempo in response and created a host of chances.
Haaland sent a header against the bar and Silva missed the rebound before De Bruyne forced Andriy Lunin to save from 25 yards.
Jack Grealish twice went close with two efforts deflected wide and De Bruyne had two attempts on goal direct from corners, with Lunin palming both over.
Phil Foden also missed the target as City kept up the pressure but Josko Gvardiol needed to block a Dani Carvajal shot to prevent Real snatching a second on the break.
City started the second half strongly and Nacho needed to scramble clear off the line with Haaland lurking after a mix-up in the Real box.
Yet Foden could only manage a weak shot at Lunin and there were signs of frustration as the game passed the hour mark with Pep Guardiola trying to rouse the crowd.
City pressed on with Grealish shooting at Lunin and their persistence finally paid off as Antonio Rudiger could only half-clear a cross from substitute Jeremy Doku and De Bruyne clipped home the loose ball.
With the crowd energised, City stepped on the accelerator and De Bruyne sent a dipping shot narrowly over before skying an even better chance.
City kept the pressure on until the end of normal time but could not find a way through Real’s stubborn defence.
Haaland was sacrificed for extra time and Foden spurned a good chance when he mis-kicked in front of goal.
Real attacks remained rare but Kyle Walker, underlining an impressive return after injury, raced back to prevent Vinicius escaping and Rudiger put a chance over.
It came down to penalties and, although Ederson lifted City by saving from Luka Modric, Lunin denied both Silva and Kovacic to send Real through.
Aldershot move into play-off places with victory at 10-man Gateshead
Kwame Thomas headed Aldershot into the National League play-off places in a 1-0 win away to a Gateshead side who played almost half the match with a defender deputising in goal.
Gateshead had goalkeeper Nathan Harness sent off in the 47th minute for bringing down James Daly outside the box and, with no stopper on the bench, Louis Storey went between the posts for the rest of the night.
Storey made a good save to keep out Cian Harries’ free-kick in the 51st minute, but could do nothing as the visitors took the lead 10 minutes later.
Thomas got on the end of a looping cross from Josh Barrett to head in, and it proved enough for a win that puts them one point above FC Halifax, who host Oldham on Thursday.
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