Manchester City edged closer to the Premier League title, while there was significant change at the bottom of the table on Sunday.
City were eliminated from the Champions League semi-finals in dramatic fashion by Real Madrid in midweek, but saw their domestic hopes boosted when Liverpool dropped points against Tottenham on Saturday.
Pep Guardiola's side subsequently breezed past Newcastle United to move three points clear of the Reds with three games remaining, while West Ham hit relegated Norwich City for four.
Elsewhere, Arsenal continued their charge for Champions League qualification with a narrow victory over 10-man Leeds United, who ended the day in the relegation zone after Everton triumphed at Leicester City.
Here, Stats Perform takes a look at the pick of the Opta data from the day's top-flight fixtures.
Manchester City 5-0 Newcastle United: Sterling provides as title charge continues
Raheem Sterling was at the double as City strengthened their grasp on top spot with a 5-0 rout of Newcastle at the Etihad Stadium.
Sterling and Aymeric Laporte struck in the first half, with Joao Cancelo teeing up the England international's opener as the full-back became the fourth of Guardiola's players to reach 10 assists in all competitions this season (also Kevin de Bruyne with 13, Phil Foden and Gabriel Jesus - both 11).
City are the only team in Europe's big five leagues to have four or more different players reach 10 assists in all competitions this campaign, and Guardiola's men furthered their advantage after the interval.
Rodri then scored following a corner, as Laporte did in the first half, as City managed their 19th and 20th goals from set-piece situations this term in the league, excluding penalties. They have conceded just once from set-pieces themselves, with their plus-19 differential the best figure recorded in a single season in the Premier League since such records are available (2006-07 onwards).
Foden added a fourth before Sterling capped a fine victory with his 51st Premier League goal at the Etihad, becoming only the second player to pass 50 strikes for City at home in the competition after Sergio Aguero (106).
City have beaten Newcastle 28 times in the Premier League (D8 L8), more than they have any other side in the competition. In their league history, they have only beaten Everton (72 times) more often than the Magpies (68 times).
Meanwhile, Eddie Howe has lost all 12 of his Premier League meetings with City – 10 of those against Guardiola – the worst 100 per cent losing record a manager has against a single opponent or against another boss in the competition.
Arsenal 2-1 Leeds United: Ill-tempered Whites fall into relegation zone
An Eddie Nketiah double kept Arsenal on course for Champions League qualification as they triumphed 2-1 against 10-man Leeds, who dropped into the bottom three for the first time since October 30.
Nketiah fired the Gunners into a 2-0 lead as he became just the second Arsenal player to score twice in the opening 10 minutes of a Premier League game after Kanu (versus Sunderland in October 2002).
With Alexandre Lacazette out of favour, Nketiah has stepped up as Mikel Arteta's talisman, scoring four goals in his last four league games – just one fewer than he had managed in his first 52 top-flight appearances.
Luke Ayling was then dismissed for a mindless two-footed lunge on Gabriel Martinelli after 27 minutes, Leeds' earliest red card in the competition since April 1998 (when Lucas Radebe saw red after 17 minutes against Everton).
Tempers continued to flare before the interval as Leeds picked up their 95th and 96th yellow cards of the season, setting a new record for the most bookings for a club within a single Premier League campaign.
Diego Llorente offered Jesse Marsch's visitors brief hope as he poked home with Leeds' first shot on target, which marked the first home league goal Arsenal have conceded from a corner since February 2021 (also against Leeds).
However, Arsenal held on for victory to move four points clear of fifth-placed Tottenham, who they face on Thursday knowing victory will secure Champions League football next campaign.
Leicester City 1-2 Everton: Toffees move out of bottom three
Mason Holgate's second-half header proved the difference as Everton climbed out of the relegation zone with a battling 2-1 victory at Leicester.
Before this game, Leicester had won eight of their last nine top-flight matches against sides starting the day inside the relegation zone (D1), but the Foxes were caught cold by Vitalii Mykolenko's early volley.
That made Mykolenko the first Ukrainian to score a Premier League goal for Everton, the 39th different nationality to find the net in the competition for the Toffees, the sixth most of all clubs.
Patson Daka restored parity five minutes later, with all five of the striker's Premier League goals coming at the King Power Stadium – only Jamie Vardy (6) has netted more often at home for the club in the top-flight in 2021-22.
Holgate delivered the decisive finish in the 30th minute with his second league goal in his last five matches, one more than he had managed across his previous 109 top-flight appearances beforehand (one).
Brendan Rodgers will be left frustrated by the nature of Holgate's goal, given it was the 15th Premier League strike Leicester have conceded from a corner this campaign – the most by a side in a single campaign since Brighton and Hove Albion in 2017-18 (16).
Victory marked the first away league win in 15 games for Everton, ending a seven-game losing streak on the road as Frank Lampard's side moved a point clear of Leeds and Burnley having played one game fewer.
Norwich City 0-4 West Ham: Bowen and Benrahma on song to down Canaries
Said Benrahma scored twice as West Ham responded to Thursday's Europa League semi-final heartbreak by cruising past relegated Norwich 4-0 at Carrow Road.
Benrahma struck after 12 minutes before Michail Antonio ended his joint-longest goal drought in the top-flight with his fifth Premier League strike against the Canaries, only against Tottenham (six) has he scored more in the competition.
Algeria international Benrahma doubled his tally before the interval, taking him to 21 direct goal contributions in the competition (nine goals, 12 assists). Since his debut in 2020, Jarrod Bowen (30) and Antonio (28) are the only other Hammers to register 20+ top-flight goal involvements.
Bowen assisted both of Benrahma's strikes as the former Hull City man became just the second player for West Ham to register at least 10 goals and 10 assists in a Premier League season, and the first since Paolo Di Canio in 1999-00 (16 goals, 13 assists).
Indeed, only Harry Kane (32) has been involved in more goals among English Premier League players in all competitions than Bowen this season (27 – 16 goals, 11 assists).
Manuel Lanzini's second-half penalty rounded off the victory as West Ham won a Premier League away game by at least a four-goal margin for just the third time, while it was the first time the Hammers have put at least four goals past a side in consecutive league visits since doing so against Tottenham in November 1966.
Meanwhile, Norwich have failed to score in 20 different league games this season, becoming the first side to do so in at least 20 matches in three different Premier League campaigns (also in 1994-95 and 2019-20).
St. Louis City v LA Galaxy: Reus sets sights on silverware after dream start
Marco Reus is desperate to bring silverware to the LA Galaxy after making a flying start to his time in MLS, with St. Louis City the destination for his first road game on Sunday.
Reus registered a goal and an assist on debut last week as the Galaxy beat Atlanta United 2-0, maintaining their grip on top spot in the Western Conference.
The Galaxy are five points clear of local rivals Los Angeles FC at the top of the standings ahead of Sunday's trip to St. Louis, who are 13th and 10 points adrift of the playoff picture.
Reus' arrival in Los Angeles has caused plenty of fanfare, but he is focused solely on the team's collective aims.
"It's not about me, it's about the team," he said. "We want to be champions. So we take it game by game.
"Besides the traffic, it's really amazing. The people are so friendly. The weather, it's really nice. When you wake up in the morning and the sun is shining, you start the day differently.
"So I'm really, really happy every morning I come into the dressing room. I'm just happy and excited."
St. Louis played out a thrilling 4-4 draw with the Portland Timbers last week, twice throwing away a two-goal lead to leave interim coach John Hackworth bewildered.
"Really don't know what to say," Hackworth said. "It's hard to imagine coming to a place like this and scoring four goals, being up, and then just losing one-versus-one defensive battles.
"Sometimes, the number of goals you give up, or the number of goals you score, can hide a lot of the transition moments.
"An easy way to prevent some of these defensive miscues from happening is to just be better with the ball."
PLAYERS TO WATCH
St. Louis City – Eduard Lowen
Lowen scored his fourth goal of the MLS season last time out, converting from the penalty spot as St. Louis drew 4-4 with the Timbers.
Only Joao Klauss, with five goals, has outscored him for St. Louis this term.
LA Galaxy – Marco Reus
Reus is one of 20 players in MLS history to record a goal and an assist on his regular-season debut.
He is also the fifth Galaxy player to do so, after Steven Gerrard, Andreas Herzog, Giovani dos Santos and Sasha Victorine. No other team have had more than two players achieve the feat.
MATCH PREDICTION – DRAW
The Galaxy have won 10 of their last 13 regular-season matches, the first time they have done so in a single season since 2011. LA have not recorded 11 wins in a span of 14 matches within a single regular season in the post-shootout era (since 2000).
It would be no surprise to see the points shared in this one, though. All three meetings between St. Louis and the Galaxy have ended level, all with different scorelines (1-1, 2-2, 3-3).
St. Louis have only won one of the last six matches in which they have held the lead in regular-season play dating back to the beginning of June (four draws, one defeat).
OPTA WIN PROBABILITY
St. Louis City – 35.8%
LA Galaxy – 38.1%
Draw – 26.1%
Raphinha hails Barcelona after statement win over Valladolid
Barcelona forward Raphinha believes the team have laid down a statement of their intent by starting the season with four straight wins in LaLiga.
Raphinha scored the first hat-trick of his career and also delivered two assists on Saturday, as Barca crushed Real Valladolid 7-0 at Camp Nou.
Hansi Flick's side already possess a four-point cushion at the top of the table after also recording victories over Valencia, Athletic Bilbao and Rayo Vallecano.
Raphinha believes their results have demonstrated the club got things right in the transfer market, telling Movistar: "Today's game has shown that there is no need for anyone else to come. We are very happy because of that.
"We are in very good shape. The team is working hard. Today's result shows what we are working for.
"We saw that the coach was on the sidelines asking for more goals and that's our mentality.
"We are hungry and want to score as many goals as we can. When we are dominant like we have been, the best way to respect our rivals is not taking the foot off the gas."
Raphinha was one of the players who faced criticism during Barca's trophyless 2023-24 campaign and was rumoured to be on his way out ahead of the new season.
The Blaugrana again battled financial restrictions throughout the window, allowing Ilkay Gundogan to leave in order to secure the registration of new arrival Dani Olmo.
With his future now certain, Raphinha is keen to nail down a starting spot and contribute on a regular basis.
"I don't know if today's was my best game, but it's certainly among my best. I will try to play even better and as much as I can," the Brazilian said.
"I'm very happy to be able to help the team. I feel good. I knew that this season would be very important for me. I'm looking for my best version to help my team-mates and be more confident."
Lazio 2-2 Milan: Leao salvages draw but Rossoneri still winless
Rafael Leao came off the bench to earn Milan a 2-2 draw with Lazio at the Stadio Olimpico on Saturday, but Paulo Fonseca's side are still without a Serie A win this season.
Milan were in front at the break through Strahinja Pavlovic's eighth-minute goal, the Serbian rising highest to power home a header from Christian Pulisic's corner.
However, Lazio hit back in the second half with Valentin Castellanos and Boulaye Dia scoring in quick succession.
Nuno Tavares' first-time ball into the centre was met by the unmarked Castellanos to level in the 62nd minute, then Dia tapped another Tavares cutback home to put the Biancocelesti ahead four minutes later.
Fonseca reacted by sending on four substitutes, and those changes had a swift impact as three of them combined for the leveller.
Theo Hernandez – who joined Leao in being dropped from the start – picked out Tammy Abraham, and his lay-off allowed Leao to escape Tavares to fire past Ivan Provedel.
The game was preceded by an emotional tribute to the man who led Lazio to their last league title, Sven-Goran Eriksson, who died at the age of 76 on Monday.
A Lazio shirt bearing the Swede's name was displayed on the home bench, while a banner held up by the home fans read: "You brought us to the top of the world... Have a good trip Mr. Sven."
Data Debrief: Milan's slow start continues
New Milan boss Fonseca is already under pressure after overseeing a return of two points from his first three league games at the helm.
It is the first time the Rossoneri have drawn two of their opening three matches in a Serie A season since 2011-12, when they also drew two and lost one,
They went on to finish second that season, just four points adrift of champions Juventus. If a title challenge is to take place this term, rapid improvements are needed.
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