Mohamed Salah, Thiago Alcantara and Trent Alexander-Arnold were all named among the substitutes for Liverpool's Premier League clash with Newcastle United on Saturday as Jurgen Klopp heavily rotated his side.
The Reds travelled to St James' Park in the early kick-off aiming to pick up the win that would see them overtake Manchester City at the top of the Premier League, albeit having played a game more.
Klopp has complained about the timing of the match, coming three days on from facing Villarreal in the first leg of their Champions League semi-final, with the return fixture to come on Tuesday.
The German coach made five changes to face Newcastle on the back of the 2-0 win over Villarreal, with Premier League top scorer Salah and fellow first-team regulars Thiago and Alexander-Arnold among those to drop out.
Fabinho and Ibrahima Konate were also named on the bench, with James Milner, Naby Keita, Joe Gomez, Joel Matip and Diogo Jota all recalled, the latter making his 50th league appearance for the Reds.
Divock Origi, who starred from the bench in last week's 2-0 win over Everton, was ruled out of the squad due to illness not related to COVID-19.
Newcastle, who had won four in a row heading into the Liverpool match, made three changes as Fabian Schar, Jonjo Shelvey and Miguel Almiron all came into the starting line-up.
Newcastle United XI: Dubravka; Krafth, Schar, Burn, Targett; Bruno Guimaraes, Shelvey, Willock; Almiron, Joelinton, Saint-Maximin.
Subs: Dummett, Lascelles, Ritchie, Manquillo, Wood, Murphy, Darlow, Gayle, Longstaff.
Liverpool XI: Alisson; Gomez, Matip, Van Dijk, Robertson; Henderson, Milner, Keita; Mane, Diaz, Jota.
Subs: Kelleher, Fabinho, Konate, Thiago, Salah, Jones, Tsimikas, Alexander-Arnold, Elliott.