With Manchester City and Liverpool facing off in the FA Cup on Saturday, the Premier League's attention turned to the race for a top-four spot.
Cristiano Ronaldo scored a hat-trick as Manchester United beat Norwich City 3-2, with the Red Devils taking full advantage of 1-0 defeats for Tottenham and Arsenal against Brighton and Hove Albion and Southampton respectively.
Elsewhere, Watford's slim survival hopes were dealt a blow as they suffered a 2-1 defeat to Brentford.
Stats Perform takes a look at some key Opta facts from the day's games.
Manchester United 3-2 Norwich City: Ronaldo racks up yet another treble
Ralf Rangnick's side delivered another disjointed performance at Old Trafford, yet they did enough to secure a 13th win in their past 16 Premier League games against the Canaries.
Ronaldo was the star of the show, the Portuguese superstar plundering the 60th hat-trick of his professional career for club and country.
The 37-year-old has now scored 20 or more goals across all competitions in each of his past 16 seasons at club level – a run that started in the 2006-07 campaign during his first spell at United.
His first goal was teed up by Anthony Elanga, who is 17 years and 81 days younger than Ronaldo. It is the greatest age gap between a United goalscorer and the player who assisted him in Premier League history.
Teemu Pukki had given Norwich hope of a memorable result when he pulled the visitors level at 2-2 from 2-0 down, the Finland international becoming the first Canaries player to score 10 or more goals in two different Premier League campaigns (11 in 2019-20 and 10 in 2021-22).
As is so often the way, though, Ronaldo had the last word.
Tottenham 0-1 Brighton and Hove Albion: Seagulls leave it late to edge out blunt hosts
Spurs missed the chance to strengthen their grip on fourth position as they suffered a third home defeat in their past six home Premier League games – as many as in their previous 14 on home soil.
Despite starting with the in-from trio of Harry Kane, Son Heung-min and Dejan Kulusevski in attack, Spurs did not manage a single shot on target. It was the first time they had failed to do so in 21 Premier League games, since November last year against Everton.
Brighton's winner came in the 90th minute through Leandro Trossard, who has now scored six goals in the top flight this season – his best-ever season return in the competition.
Graham Potter's side have now won consecutive away league games for the first time since September 2021 and are unbeaten in three Premier League games, winning the last two, after losing each of the six before that.
Southampton 1-0 Arsenal: Wasteful Gunners punished by Saints
Arsenal missed the chance to pull level on points with Tottenham after a third consecutive Premier League defeat, having lost just two of their previous 13.
The Gunners dominated at St Mary's, taking 23 shots and enjoying 76 per cent possession. There have been 11 instances of a team failing to score having taken 20 or more shots in a Premier League match this season, with Arsenal responsible for three of those.
They were undone by Jan Bednarek's goal on the stroke of half-time, the first they have conceded from a corner situation in the top flight this season.
Bednarek has now scored four goals in 27 Premier League games this season, which is one more than he scored in his previous four campaigns combined (three in 100 appearances).
Watford 1-2 Brentford: Hornets' miserable home run continues
Pontus Jansson's 95th-minute winner for Brentford meant Watford became only the third team to lose 10 consecutive top-flight home games in a row, after Birmingham City in February 1986 and Sunderland in August 2005.
Alongside Birmingham, they are only the second to do so within a single season.
That run means Hornets boss Roy Hodgson is the first manager to lose his first five home Premier League games in charge of a club since Chris Ramsey with QPR in 2015.
Brentford, meanwhile, have won five of their last six Premier League games (L1) and have won three top-flight games in a row for the first time since September 1946.
Cleverley: Watford 'deserved to win' after improved second half
Tom Cleverley believes Watford "deserved the three points" after an improved second-half display saw them beat Oxford United 1-0.
Vakoun Bayo scored the only goal of the match in the 54th minute after he turned in the rebound of his own saved shot.
It is the fifth goal he has scored in three games, having also netted four times in the Hornets' 6-2 victory over Sheffield Wednesday last weekend.
The hosts registered 12 shots, seven of which were on target, as they upped the pressure after the break. They only had four attempts in the first half, though Ciaron Brown had to clear an in-swinging Watford corner off his own goal line on the stroke of half-time.
The three points lift Watford up to fourth in the Championship table ahead of the rest of the weekend's fixtures, and Cleverley was pleased with the marked improvement he saw in the second 45 minutes.
"I thought the second-half performance was really good until the last five minutes really," he told Sky Sports.
"I thought we didn't manage the game as well as we could do and a few refereeing decisions - dubious one that went against us - meant they could get the ball in our box.
"So, it felt a bit hands to the pump at the end, but I thought for the first 35 minutes of the second half, we were absolutely fantastic and were unlucky not to make it two, three.
"Understandably flat performance in the first half, probably from both teams with it being such a demanding week.
"But I thought our second-half performance in the main deserved the three points and our supporters helped us through."
Meanwhile, Oxford remain 16th and have now won just one of their last 10 matches in the Championship.
They failed to register a single shot on target in the first half, and are yet to win a game when conceding the opening goal in the league this season, with this the fifth such match they have gone behind.
It was Oxford's sixth defeat of the season and while manager Des Buckingham said there were positives to take, he was left frustrated by their lack of a clinical edge.
"I'm extremely proud but extremely frustrated," he said.
"I'm disappointed we haven't come away with something. I felt we created enough, we just haven't taken them. If we keep playing that way, we will be fine.
"We speak about being a together group. We did well, but Watford took their chance."
'When we get to that level, we're unstoppable' - Shaw hits hat-trick in Man City rout
Khadija Shaw believes Manchester City are "unstoppable" when they raise their level after securing a resounding 4-0 win over Tottenham in the Women's Super League.
Shaw made history, overtaking Vivianne Miedema as the player with the most WSL hat-tricks and becoming the first player in the league to net three separate trebles against the same side.
The Jamaican opened the scoring after just 23 seconds, robbing Clare Hunt of the ball, before adding to her tally in the 15th and 67th minutes to take the match ball home. Jill Roord had added City's third 91 seconds before Shaw wrapped up her hat-trick.
City dominated throughout, with Lauren Hemp also unlucky not to end up on the scoresheet after hitting both posts and the bar with a pacy strike from inside the box.
It was a win that moved City four points clear at the top of the WSL table ahead of Chelsea's match at Liverpool on Sunday.
Shaw was delighted to walk away with the match ball, but especially with the quality that City have shown so far this campaign.
"We really enjoyed that one," Shaw told Sky Sports. "We spoke as a team that we wanted to come out here and be on the front foot.
"Fortunately for me, with my pressing that I've been working on, we managed to get the goal. It was a good night.
"With the players that I have around me, I know that I’m going to get crosses, it's just making the right movements in the box and they will find me. I've just been getting better and growing, so I'm happy.
"At the back end of last season, we just fell short with the goal difference. It's about staying consistent, because we know we have the quality.
"Once we go at every game on the front foot from the first whistle, we're really good at that. We have to keep going and see where we can raise the level even better, so when we get to that level, we're unstoppable."
City have won their last nine matches in all competitions, scoring seven goals without reply in their last two WSL outings.
Despite their emphatic win at the Etihad Stadium on Friday though, Gareth Taylor still believes there is room for improvement from his side, especially with reigning champions Chelsea next up for them in the league.
"I said to them, I think we can be better," Taylor told Sky Sports.
"I thought at times tonight we were a little bit loose. A little bit slow with our play. It's really difficult to be critical because it's a different environment for us."
Guardiola confident Man City can avoid fourth straight loss
Pep Guardiola is facing the prospect of losing four consecutive matches for the first time in his career but is confident Manchester City do not need extra reassurance.
All three of City's recent losses have come in different competitions, first falling to Tottenham in the EFL Cup round of 16 before following it up with defeats to Bournemouth in the Premier League and Sporting CP in the Champions League.
It is the first time the Citizens have been on such a run since doing so between May and August 2021, while in the same season, it is the first time since April 2018.
In the Premier League, Guardiola's men were on a 32-match unbeaten run before their defeat to Bournemouth, and they have only lost two consecutive top-flight matches three times under the Spaniard before.
The Spaniard has been vocal about his team's recent injury struggles, and will once again be without Jack Grealish, despite his recent England call-up, John Stones and Ruben Dias for the trip to Brighton on Saturday.
Bernardo Silva said the team were in a "dark place" after their game at Sporting on Tuesday, but Guardiola does not believe he needs to provide any extra motivation to help get his players back to winning ways.
"I don't think [the players need extra reassurance]. Of course, we are not used to losing three games in three different competitions, but it is football, and it has happened," Guardiola said.
"We know the reason why we struggle, but we are looking forward to this game and after the international break, and after that a few players will be back and recovered. All the little problems we have with players will be solved. I hope.
"There always is a first time [to lose four straight]. Hopefully, it is not the case.
"Twenty minutes against Fulham we were not good, against Bournemouth we were not good, but the rest of the games we were good. We are good. We will see what happens."
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