Thomas Tuchel will expect Chelsea to mark his 50th Champions League game as a boss with a win at Lille and Juve will be favourites to knock Villarreal out on Wednesday.
There is huge uncertainty at Stamford Bridge after Roman Abramovich put the club up for sale before having his assets frozen by the United Kingdom government, but the London club have won four consecutive games.
The holders travel to Lille for the second leg of the round-of-16 tie with a 2-0 lead courtesy of goals from the in-form Kai Havertz and Christian Pulisic.
Juve and Villarreal will start their showdown at the Allianz Stadium locked at 1-1 after Dani Parejo equalised following Dusan Vlahovic's early strike.
Stats Perform picks out the standout Opta data ahead of the two games.
Lille v Chelsea
Havertz has become the Blues' main man, scoring four goals in his past three matches and six in seven.
Chelsea head coach Tuchel has won 31 of his 49 matches and can set a record for the most victories in his first 50 games as a boss in the competition with another success in Lille, as he is currently level with Zinedine Zidane's tally.
Lille's chances of forcing their way back into the tie appear to be slim, as not only do they trail by two goals, they have lost their past three Champions League games against the Premier League club.
They have also been eliminated from each of their three previous European knockout ties after losing the first leg.
The last side to progress against Champions League holders after failing to score in the opening leg was Arsenal versus Milan in 2007-08, with the first leg a goalless draw.
Each of Chelsea's past 11 wins in the Champions League have come with a clean sheet, 10 of which have come under Tuchel in just 14 matches.
Juventus v Villarreal
January signing Vlahovic set a record for the quickest goal by a Champions League debutant when he was on target after only 32 seconds of the first leg.
Juve are without a win in each of their past seven first-leg games in the Champions League (D3 L4), going on to be eliminated from four of their previous five knockout ties in the competition.
Villarreal have won their past two away games in the Champions League, the same number of victories as they managed across the 15 such matches beforehand.
Juve have only lost three of their previous 23 Champions League matches at home to Spanish sides in this competition, winning 12 and drawing eight.
This will be Villarreal’s first visit to Juventus in any competition as they scent a place in the quarter-finals.
Juan Cuadrado is in line to make his 50th appearance for Bianconeri in the Champions League. He has provided 11 assists for the Serie A giants in the competition, which is the most by any player in the period since he first joined the club in 2015.
PSG made to wait for Ligue 1 title after Monaco overcome Lille
PSG were forced to put their Ligue 1 title celebrations on ice after second-placed Monaco overcame Lille on Wednesday.
Luis Enrique's side swept aside Lorient 4-1 after doubles from Ousmane Dembele and Kylian Mbappe, putting the pressure on the chasing Monaco.
Yet Youssouf Fofana's third league goal of the season edged Adi Hutter's team to a 1-0 victory, delaying PSG's inevitable title success – barring a miraculous collapse.
PSG, who also have a two-legged Champions League semi-final with Borussia Dortmund to come in May, are 11 points clear with just four top-flight games remaining.
Having lost just once in Ligue 1 all season, PSG would secure back-to-back top-flight crowns if they overcome Le Havre on Saturday at Parc des Princes.
Though victory appears likely against relegation-threatened Le Havre, the Parisians would still be crowned champions without victory if Monaco fail to win on their visit to Lyon the following day.
Given the clash with Dortmund comes just four days after meeting Le Havre, Luis Enrique may rest the likes Bradley Barcola, Marquinhos, Achraf Hakimi, Vitinha and Warren Zaire-Emery, as he did against Lorient.
While the title remains in PSG's hands, Monaco at least took a step closer to Champions League qualification with victory over Lille, sitting 10 points clear of fifth-placed Nice.
Xavi commits U-turn and elects to stay at Barcelona
Barcelona head coach Xavi will continue in his role next season after an unexpected reversal of his decision to leave at the end of the 2023-24 campaign, according to widespread reports.
The former Barcelona midfielder announced in January that he would walk away from the job at the end of the current season, even though his contract was due to run until the end of the following term.
Xavi acknowledged the Barcelona role had taken its toll but reportedly changed his plans after a meeting with Blaugrana president Joan Laporta on Wednesday.
The 44-year-old was initially appointed as Barca coach in 2021 before leading the LaLiga giants to the top-flight title in the 2022-23 campaign.
Xavi's initial announcement of his intentions to depart Barcelona came after a tough period following defeats to Girona, Real Madrid and Athletic Club before revealing the news in the aftermath of a 5-3 loss to Villarreal.
The Blaugrana turned their fortunes around after that decision became public, though, going 13 games unbeaten across all competitions.
Unsurprisingly, that run encouraged Laporta, vice president Rafa Yuste and sporting director Deco to plead with Xavi to continue until the end of his agreed contract.
Though that undefeated streak ended with a 4-1 defeat to Paris Saint-Germain that dumped Barcelona out of the Champions League quarter-finals, Xavi has now agreed to stay in his role.
The league title is almost out of reach this term, however, as Real Madrid moved 11 points clear of second-placed Barca with Sunday's 3-2 Clasico victory.
Liverpool line up Feyenoord coach Slot as Klopp replacement
Arne Slot appears to be at the front of the queue to replace Jurgen Klopp as Liverpool manager.
Klopp confirmed in January that he would be leaving the Reds at the end of the season.
Xabi Alonso, who has led Bayer Leverkusen to their first Bundesliga title, was swiftly established as a leading candidate to take the helm at Anfield, where he starred as a player for the Reds between 2004 and 2009.
The 42-year-old, however, is staying put in Germany, and Liverpool's search for Klopp's successor has taken them to Feyenoord's door.
Slot has been previously linked to jobs in the Premier League. Leeds United wanted to appoint him last season before their relegation to the Championship, while he was targeted by Tottenham before they appointed Ange Postecoglou.
The Dutchman intimated when linked with Spurs: "A normal next step would be to go abroad and I've always said that the best league in the world is the Premier League."
Ideally, Liverpool will be aiming for a coach who can come close to replicating Klopp's style of play, and in particular has a flair for working with and developing young players.
Slot has enjoyed fantastic success in Rotterdam. He became Feyenoord head coach in December 2022, after leaving AZ, and went on to win the Eredivisie title in 2022-23, having reached the Europa League final in the previous season.
The 45-year-old has a 64.4 per cent win record from 146 games in charge, winning 94, drawing 29 and losing just 23.
His Feyenoord team have scored 329 goals, an average of 2.2 per match, conceding 147 in return. Slot's points per game is a hugely impressive 2.13.
Feyenoord are, though, set to relinquish their Eredivisie crown, as they trail leaders PSV by nine points. They have, however, won the KNVB Cup this term.
As there is no break clause in the Dutchman's contract, it has been reported that a compensation fee in the region of €10million (£8.5m) could prise him away from Feyenoord.
Sporting CP boss Ruben Amorim is another coach who has been heavily linked with the Liverpool job, albeit he is reportedly in talks with West Ham.
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